Works Published in 2012
Displaying works 81 - 100 of 202 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2012 journal article
Epidemiology and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus Strains of Porcine Origin
Journal of Clinical Microbiology, 50(11), 3687–3693.
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Carrier State / epidemiology; Carrier State / microbiology; Carrier State / veterinary; Cluster Analysis; Electrophoresis, Gel, Pulsed-Field; Genotype; Meat / microbiology; Methicillin-Resistant Staphylococcus aureus / classification; Methicillin-Resistant Staphylococcus aureus / genetics; Methicillin-Resistant Staphylococcus aureus / isolation & purification; Microbial Sensitivity Tests; Micrococcal Nuclease / genetics; Molecular Epidemiology; Multilocus Sequence Typing; Multiplex Polymerase Chain Reaction; Nasal Mucosa / microbiology; Ohio / epidemiology; Penicillin-Binding Proteins; Perineum / microbiology; Prevalence; Staphylococcal Infections / epidemiology; Staphylococcal Infections / microbiology; Staphylococcal Infections / veterinary; Swine
TL;DR:
The results of this study confirm that MRSA, including LA-MRSA, is common in herds of swine in Ohio and is shown to persist in the farm to processing and retail continuum.
(via Semantic Scholar)
jcm.asm.org (publisher PDF)
Source: Crossref
Added: July 21, 2019
2012 journal article
Surgical treatment of a pulmonary artery vascular hamartoma in a dog
Journal of the American Veterinary Medical Association, 240(7), 858–862.
MeSH headings : Animals; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Hamartoma / surgery; Hamartoma / veterinary; Male; Pulmonary Artery / pathology; Pulmonary Artery / surgery; Vascular Neoplasms / pathology; Vascular Neoplasms / surgery; Vascular Neoplasms / veterinary
TL;DR:
Computed tomography was helpful in predicting the resectability of the intracardiac mass in this dog, and treatment with arteriotomy under inflow occlusion and mild hypothermia resulted in a favorable outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: July 21, 2019
2012 journal article
Uropathogenic E. coli Promote a Paracellular Urothelial Barrier Defect Characterized by Altered Tight Junction Integrity, Epithelial Cell Sloughing and Cytokine Release
Journal of Comparative Pathology, 147(1), 11–19.
author keywords: cytokine; tight junction; urinary tract infection; urothelial permeability
MeSH headings : Animals; Cell Membrane Permeability / physiology; Cytokines / metabolism; Diffusion Chambers, Culture; Dogs; Electric Conductivity; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Epithelial Cells / pathology; Tight Junctions / pathology; Tight Junctions / ultrastructure; Tissue Culture Techniques; Urinary Bladder / metabolism; Urinary Bladder / microbiology; Urinary Bladder / pathology; Uropathogenic Escherichia coli / physiology; Urothelium / metabolism; Urothelium / microbiology; Urothelium / pathology
TL;DR:
A potential role for IL-15 is pointed to in UTI-induced urothelial injury after changes in both tissue ultrastructure and TER indicated that uropathogenic E. coli infection promotes a paracellular permeability defect associated with the failure of umbrella cell tight junction formation and umbrella cell sloughing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 21, 2019
2012 journal article
Deficient Plakophilin-1 Expression Due to a Mutation in PKP1 Causes Ectodermal Dysplasia-Skin Fragility Syndrome in Chesapeake Bay Retriever Dogs
PLoS ONE, 7(2), e32072.
Ed(s): J. Brandner
MeSH headings : Animals; DNA Primers / genetics; Desmosomes / metabolism; Disease Models, Animal; Dogs; Ectodermal Dysplasia / genetics; Gene Expression Regulation; Keratins / chemistry; Microscopy, Electron / methods; Microscopy, Electron, Transmission / methods; Mutation; Phenotype; Plakophilins / biosynthesis; Plakophilins / genetics; Sequence Analysis, DNA / methods; Skin / pathology; Skin Diseases / genetics; Skin Diseases / metabolism
TL;DR:
The clinical and pathological findings, along with the PKP1 mutation, were consistent with the diagnosis of ectodermal dysplasia-skin fragility syndrome with plakophilin-1 deficiency, a novel congenital acantholytic dermatosis that developed in Chesapeake Bay retriever dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Crossref
Added: July 21, 2019
2012 journal article
Bilaterally Symmetrical Alopecia With Reticulated Hyperpigmentation
Veterinary Pathology, 50(4), 682–685.
author keywords: alopecia; autoimmunity; dog diseases; hair follicle; lupus
MeSH headings : Alopecia / immunology; Alopecia / pathology; Alopecia / veterinary; Animals; Autoimmunity; Biopsy; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Folliculitis / immunology; Folliculitis / pathology; Folliculitis / veterinary; Hair Follicle / pathology; Hyperpigmentation / immunology; Hyperpigmentation / pathology; Hyperpigmentation / veterinary; Lupus Erythematosus, Discoid / immunology; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Lupus Erythematosus, Systemic / immunology; Lupus Erythematosus, Systemic / pathology; Lupus Erythematosus, Systemic / veterinary; Male; Skin / pathology
TL;DR:
An adult castrated male Doberman Pinscher was presented with a 6-month history of well-demarcated alopecic patches with reticulated hyperpigmentation and fine peripheral scaling, eventually associated with the development of systemic lupus erythematosus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 21, 2019
2012 journal article
Cost effective and time efficient measurement of CD4, CD8, major histocompatibility complex Class II, and macrophage antigen expression in the lungs of chickens
Veterinary Immunology and Immunopathology, 146(3-4), 225–236.
author keywords: imageJ; Chicken; Marek's disease; Lung; CD4; CD8; Major histocompatibility complex Class II; Macrophages
MeSH headings : Animals; Antigens, Viral / immunology; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Chickens; Herpesvirus 2, Gallid / genetics; Herpesvirus 2, Gallid / immunology; Histocompatibility Antigens Class II / immunology; Image Processing, Computer-Assisted / methods; Image Processing, Computer-Assisted / standards; Immunohistochemistry / veterinary; Lung Diseases / diagnosis; Lung Diseases / immunology; Lung Diseases / veterinary; Macrophages, Alveolar / chemistry; Macrophages, Alveolar / immunology; Marek Disease / diagnosis; Marek Disease / immunology; Marek Disease / virology; Poultry Diseases / diagnosis; Poultry Diseases / immunology; Poultry Diseases / virology; RNA, Viral / chemistry; RNA, Viral / genetics; Random Allocation; Real-Time Polymerase Chain Reaction / veterinary; Retrospective Studies; Specific Pathogen-Free Organisms
TL;DR:
Using imageJ as described eliminates the need for subjective and less reproducible methods for measuring expression of these antigens, and is faster and more reproducible than manual counting in cases (CD4 and CD8) where the number of positive cells is low enough for manual counts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 21, 2019
2012 journal article
Standardization of a model to study revaccination against Marek's disease under laboratory conditions
Avian Pathology, 41(1), 59–68.
MeSH headings : Animals; Chickens; DNA Primers / genetics; Female; Immunization, Secondary / methods; Immunization, Secondary / veterinary; Lymphoid Tissue / pathology; Male; Marek Disease / prevention & control; Marek Disease Vaccines; Models, Animal; Real-Time Polymerase Chain Reaction / veterinary
TL;DR:
The results show that revaccination protocols might aid in solving major drawbacks associated with various highly protective experimental MD vaccines; that is, lymphoid organ atrophy and residual virulence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 21, 2019
2012 journal article
The length scale of selection in protein evolution
Fly, 6(1), 16–20.
author keywords: molecular evolution; epistasis; fitness landscape; protein; correlation function; length scale; Drosophila; positive selection; molecular clock; overdispersion
MeSH headings : Animals; Drosophila; Drosophila Proteins / chemistry; Drosophila Proteins / genetics; Drosophila melanogaster; Evolution, Molecular; Selection, Genetic
TL;DR:
The evidence presented in the study supporting a substantial role for epistasis in the process of molecular evolution is focused on, and the implications of this widespread epistasis on the overdispersion of the molecular clock and the efficacy of common tests for positive selection are discussed.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: July 21, 2019
2012 journal article
Proteasome Inhibition of Pathologic Shedding of Enterocytes to Defend Barrier Function Requires X-Linked Inhibitor of Apoptosis Protein and Nuclear Factor κB
Gastroenterology, 143(1), 133–144.e4.
author keywords: Protozoan; Intestine; Parasitic Infection; Cell Death
MeSH headings : Animals; Apoptosis; Caspase 3 / metabolism; Cryptosporidiosis / metabolism; Cryptosporidium parvum; Disease Models, Animal; Enterocytes / metabolism; Enterocytes / microbiology; Ileum / microbiology; Ileum / physiopathology; Intestinal Mucosa / metabolism; NF-kappa B / metabolism; Proteasome Endopeptidase Complex / metabolism; Signal Transduction; Swine; X-Linked Inhibitor of Apoptosis Protein / metabolism
TL;DR:
A pathway by which villus epithelial cells are maintained during C parvum infection is identified, which might be used to promote clearance of minimally invasive enteropathogens, such as by increasing the rate of migration of epithelial Cells from the crypt to the villus tip.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID, NC State University Libraries
Added: July 20, 2019
2012 journal article
Administration of Fozivudine Tidoxil as a Single-Agent Therapeutic during Acute Feline Immunodeficiency Virus Infection Does Not Alter Chronic Infection
Viruses, 4(6), 954–962.
author keywords: acquired immunodeficiency syndrome; lentivirus; FIV; antiretroviral therapy (ART); Zidovudine; Fozivudine
MeSH headings : Animals; Anti-HIV Agents / administration & dosage; CD4-CD8 Ratio; Cat Diseases / drug therapy; Cats; Feline Acquired Immunodeficiency Syndrome / drug therapy; Feline Acquired Immunodeficiency Syndrome / virology; Lipids / administration & dosage; Lymphocyte Count; Treatment Outcome; Viral Load; Viremia / virology; Zidovudine / administration & dosage; Zidovudine / analogs & derivatives
TL;DR:
It is suggested that treatment with a single agent anti-retroviral drug during acute lentivirus infection does not significantly alter viral load and immune function during the chronic, asymptomatic stage of infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: July 20, 2019
2012 journal article
Evaluation of Cyclooxygenase Protein Expression in Traumatized Versus Normal Tissues from Eastern Box Turtles (Terrapene Carolina Carolina)
Journal of Zoo and Wildlife Medicine, 43(2), 289–295.
author keywords: Chelonian; eastern box turtle; Terrapene carolina; cyclooxygenase-1; cyclooxygenase-2; nonsteroidal anti-inflammatory drug
MeSH headings : Animals; Cyclooxygenase 1 / genetics; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Gene Expression Regulation, Enzymologic / physiology; Muscle, Skeletal / enzymology; Turtles; Wounds and Injuries / metabolism; Wounds and Injuries / veterinary
TL;DR:
Traditional nonsteroidal anti-inflammatory drugs that block both COX isoforms might be more efficacious than COX-2–selective drugs, and NSAIDs should be evaluated for potential liver and kidney toxicity in turtles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 20, 2019
2012 journal article
Bartonellaspp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region
Emerging Infectious Diseases, 18(5).
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Arthritis / microbiology; Bacteremia / diagnosis; Bacteremia / epidemiology; Bacteremia / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Lyme Disease / epidemiology; Male; Middle Aged; Molecular Typing; Serotyping; Surveys and Questionnaires; Young Adult
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: July 20, 2019
2012 journal article
A Case of Enzootic Nasal Adenocarcinoma in a Ewe
Case Reports in Veterinary Medicine, 2012, 1–4.
TL;DR:
An approximately 2-year-old open Suffolk ewe presented to the North Carolina State University College of Veterinary Medicine Veterinary Health Complex for evaluation of a left nasal mass, and IHC and RT-PCR identified the presence of enzootic nasal tumor virus and confirmed the final diagnosis of enzooting nasal adenocarcinoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019
2012 chapter
Vitamin A deficiency and the neonatal immune system: possible effects of vitamin A supplementation at birth
In Report: WHO technical consultation on vitamin A in newborn health: mechanistic studies. Geneva: World Health Organization.
Source: NC State University Libraries
Added: June 20, 2019
2012 journal article
Unilateral Epididymitis Associated with Salmonella Bacteremia in a Dog
Clinical Theriogenology, 4(1), 61–65.
Source: NC State University Libraries
Added: February 18, 2019
2012 journal article
phenoypical characterization and isolation of a subpopulation of myeloid cells from swine peripheral blood: new method to isolate plasmacytoid dendritic cells: p0920
Immunology, 137, 482.
Source: ORCID
Added: February 11, 2019
2012 journal article
Virus-like particles: the new frontier of vaccines for animal viral infections.
Veterinary Immunology and Immunopathology, 148(3-4), 211–225.
author keywords: Virus-like particles (VLPs); Animal vaccines; Vaccine vectors
MeSH headings : Animals; Chickens / immunology; Chickens / virology; Poultry Diseases / prevention & control; Poultry Diseases / virology; Swine / immunology; Swine / virology; Swine Diseases / prevention & control; Swine Diseases / virology; Vaccines, Virus-Like Particle / immunology; Vaccines, Virus-Like Particle / therapeutic use; Virus Diseases / immunology; Virus Diseases / prevention & control; Virus Diseases / veterinary
TL;DR:
The current status of VLPs as a vaccine technology in the veterinary field is reviewed, and the potential advantages and challenges of this technology are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2012 journal article
Immunomodulatory properties of beta-sitosterol in pig immune responses.
International Immunopharmacology, 13(3), 316–321.
author keywords: Phytosterols; Immunomodulator; PRRSV; Swine
MeSH headings : Animal Feed; Animals; Apolipoprotein A-I / blood; Dendritic Cells / drug effects; Dendritic Cells / immunology; Female; Immunologic Factors / administration & dosage; Immunologic Factors / pharmacology; In Vitro Techniques; Leukocyte Count; Lymphocyte Activation / drug effects; Male; Porcine respiratory and reproductive syndrome virus / immunology; Sitosterols / administration & dosage; Sitosterols / pharmacology; Spain; Sus scrofa / blood; Sus scrofa / immunology; Viral Vaccines / administration & dosage
TL;DR:
The data in this report show that BSS can be considered an immunomodulator in pigs after vaccination with porcine reproductive and respiratory syndrome virus (PRRSV) modified life vaccine (MLV).
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2012 journal article
Immunogenic properties of calicivirus-like particles as vaccine vectors
Source: ORCID
Added: February 11, 2019
2012 journal article
Chimeric calicivirus-like particles elicit specific immune responses in pigs
Vaccine, 30(14), 2427–2439.
author keywords: RHDV-VLPs; Vaccine vector; 3A; FMDV; Pigs
MeSH headings : Acute-Phase Proteins / metabolism; Amino Acid Sequence; Animals; Antibodies, Viral / immunology; Antibody Specificity; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / metabolism; Epitopes, T-Lymphocyte / chemistry; Epitopes, T-Lymphocyte / immunology; Hemorrhagic Disease Virus, Rabbit / immunology; Humans; Immunity; Immunity, Cellular; Male; Molecular Sequence Data; Swine / immunology; Vaccines, Virus-Like Particle / immunology; Viral Proteins / chemistry; Viral Proteins / immunology
TL;DR:
This is the first immunological report on the potential use of chimeric R HDV-VLPs as antigen carriers in pigs and the adjuvanted group exhibited the highest IFN-γ-secreting cell numbers and lymphoproliferative specific T cell responses against 3A epitope and RHDV-VLP.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 11, 2019
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