Works Published in 2007
Displaying works 41 - 60 of 166 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2007 journal article
Neuronal nitric oxide synthase and calbindin delineate sex differences in the developing hypothalamus and preoptic area
Developmental Neurobiology, 67(10), 1371–1381.
author keywords: sex differences; hypothalamus; preoptic area; nitric oxide; calbindin
MeSH headings : Animals; Biomarkers / analysis; Biomarkers / metabolism; Calbindins; Calcium-Binding Proteins / metabolism; Female; Hypothalamus / growth & development; Hypothalamus / metabolism; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins / metabolism; Neurons / metabolism; Nitric Oxide / biosynthesis; Nitric Oxide Synthase Type I / metabolism; Preoptic Area / growth & development; Preoptic Area / metabolism; Receptors, Androgen / metabolism; S100 Calcium Binding Protein G; Sex Characteristics; Sex Differentiation / physiology; Sexual Maturation / physiology
TL;DR:
It is suggested that NO as an effector molecule and calbindin as a molecular biomarker illuminate key aspects of sexual differentiation in the developing mouse brain.
(via Semantic Scholar)
europepmc.org (repository)
Source: Crossref
Added: August 28, 2020
2007 journal article
Short birth intervals and uterine cervical cancer risk in Jamaican women
International Journal of Gynecology & Obstetrics, 98(1), 56–57.
author keywords: cervix; neoplasms; parity; risk factors; pregnancy intervals
MeSH headings : Birth Intervals; Case-Control Studies; Female; Humans; Jamaica; Papillomaviridae; Papillomavirus Infections / complications; Parity; Pregnancy; Registries; Risk Factors; Uterine Cervical Neoplasms / epidemiology; Uterine Cervical Neoplasms / ethnology
TL;DR:
Whether short birth-intervals increase CC risk incident cases were identified through the Kingston-St Andrews Jamaica Cancer Registry and controls were identified from cytology log-books of facilities where cases were diagnosed and response rates were 82% and 60% respectively.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2007 journal article
In vitro molecular mechanisms of bisphenol A action
Reproductive Toxicology, 24(2), 178–198.
Contributors: Y. Wetherill*, B. Akingbemi *, J. Kanno *, J. McLachlan*, A. Nadal *, C. Sonnenschein *, C. Watson*, R. Zoeller *, S. Belcher*
author keywords: bisphenol A (BPA, 2,2-bis(4-hydroxyphenyl) propane; endocrine disruption; endocrine disrupting chemical (EDC); rapid signaling; estrogen receptor; androgen receptor; thyroid receptor; thyroid hormone; GPR30; non-classical membrane estrogen receptor; immune system; allergic resonse; in vitro mechanisms; cell specificity; expert panel review
MeSH headings : Animals; Benzhydryl Compounds; Dose-Response Relationship, Drug; Endocrine Disruptors / pharmacokinetics; Endocrine Disruptors / toxicity; Environmental Exposure / analysis; Female; Fertility / drug effects; Humans; Male; Phenols / chemistry; Phenols / pharmacokinetics; Phenols / toxicity; Reproduction / drug effects
TL;DR:
This review is a detailed review of published studies that have focused on the mechanistic basis of BPA action in diverse experimental models and an assessment of the strength of the evidence regarding the published BPA research.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2007 journal article
Blooms of Pseudo-nitzschia and domoic acid in the San Pedro Channel and Los Angeles harbor areas of the Southern California Bight, 2003–2004
Harmful Algae, 6(3), 372–387.
author keywords: domoic acid; harmful algal blooms; Los Angeles; Pseudo-nitzschia; Southern California
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
Degradation of the encephalomyocarditis virus and hepatitis A virus 3C proteases by the ubiquitin/26S proteasome system in vivo
Virology, 360(2), 350–363.
Contributors: P. Schlax*, J. Zhang *, E. Lewis*, A. Planchart* & T. Lawson*
author keywords: 3C protease; encephalornyocarditis; hepatitis A; picornavirus; proteasome; proteolysis; ubiquitin
MeSH headings : 3C Viral Proteases; Animals; Cell Line; Cell Nucleus / chemistry; Cell Survival; Cysteine Endopeptidases / biosynthesis; Cysteine Endopeptidases / genetics; Cysteine Endopeptidases / metabolism; Cytoplasm / chemistry; Encephalomyocarditis virus / enzymology; Fibroblasts / virology; Hepatitis A virus / enzymology; Humans; Mice; Proteasome Endopeptidase Complex / metabolism; Protein Processing, Post-Translational; Ubiquitin / metabolism; Viral Proteins / biosynthesis; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR:
The absence of polyubiquitinated EMCV 3C protease conjugates in nuclear fraction preparations suggests that localization to the nucleus can protect this protein from ubiquitination.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2007 journal article
Destruction of estrogenic activity in water using UV advanced oxidation
Science of The Total Environment, 377(1), 105–113.
author keywords: ultraviolet; water treatment; AOP; YES; endocrine disrupter; kinetics; model
MeSH headings : Endocrine Disruptors / analysis; Endocrine Disruptors / radiation effects; Estrogens, Non-Steroidal / analysis; Estrogens, Non-Steroidal / radiation effects; Oxidation-Reduction; Ultraviolet Rays; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / radiation effects; Water Purification / methods
TL;DR:
These compounds, when considered at environmentally relevant levels, are significantly degraded at much lower UV fluences than previously thought.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
Biological assessments of a mixture of endocrine disruptors at environmentally relevant concentrations in water following UV/H2O2 oxidation
Science of The Total Environment, 376(1-3), 18–26.
author keywords: endocrine disrupting compounds (EDCs); UV/H2O2 oxidation process; yeast estrogen screen (YES); vitellogenin (VTG)
MeSH headings : Animals; Benzhydryl Compounds; Drug Interactions; Endocrine Disruptors / toxicity; Estradiol / toxicity; Estrogens / toxicity; Ethinyl Estradiol / toxicity; Hydrogen Peroxide / chemistry; Male; Oryzias / metabolism; Oxidants / chemistry; Oxidation-Reduction; Phenols / toxicity; Photolysis; Receptors, Estrogen / metabolism; Rivers; Ultraviolet Rays; Vitellogenins / biosynthesis; Water Pollutants, Chemical / toxicity; Water Purification / methods; Yeasts / metabolism
TL;DR:
The removal rates of in vitro and in vivo estrogenic activity of the EDC mixtures were lower than those observed for single compounds, and slower in natural waters, likely due to lower steady-state concentrations of hydroxyl radicals in the presence of *OH scavengers from the water matrix and EDC mixture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
Comparisons of polychromatic and monochromatic UV-based treatments of bisphenol-A in water via toxicity assessments
Chemosphere, 68(6), 1041–1049.
MeSH headings : Animals; Benzhydryl Compounds; Embryo, Nonmammalian / drug effects; Endocrine Disruptors / analysis; Endocrine Disruptors / radiation effects; Endocrine Disruptors / toxicity; Hydrogen Peroxide / chemistry; Oryzias; Oxidation-Reduction / radiation effects; Phenols / analysis; Phenols / radiation effects; Phenols / toxicity; Photolysis / radiation effects; Ultraviolet Rays; Waste Disposal, Fluid / methods
TL;DR:
Results demonstrated that MP-UV direct photolysis more effectively removed BPA and associated estrogenic activity compared to LP-UV lamps, and no significant difference was found between the two lamps under UV/H2O2 oxidation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
Estrogenic modulation of CYP3A38, CYP3A40, and CYP19 in mature male medaka (Oryzias latipes)
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 145(3), 370–378.
author keywords: CYP19; CYP3A; endocrine-disruption; estrogenic modulation; medaka; testosterone
MeSH headings : Animals; Aromatase / biosynthesis; Aromatase / genetics; Cytochrome P-450 CYP3A / biosynthesis; Cytochrome P-450 CYP3A / genetics; Dose-Response Relationship, Drug; Estradiol / pharmacology; Ethinyl Estradiol / pharmacology; Male; Oryzias / metabolism; RNA, Messenger / analysis; Testosterone / metabolism; Vitellogenins / biosynthesis
TL;DR:
Estrogenic exposure induced Vtg production, suppressed CYP3A protein production, downregulated TE metabolism, and enhanced CYP19 activity, which could contribute to Vtg induction in male medaka.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
An in vivo Look at Vertebrate Liver Architecture: Three-Dimensional Reconstructions from Medaka (Oryzias latipes)
The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology, 290(7), 770–782.
author keywords: liver; hepatobiliary; biliary; liver architecture; comparative hepatology; fish; 3-dimensional structure; liver structure and function
MeSH headings : Animals; Biliary Tract / cytology; Biliary Tract / ultrastructure; Computer Simulation; Epithelial Cells / ultrastructure; Fluorescent Dyes; Hepatocytes / ultrastructure; Imaging, Three-Dimensional; Liver / blood supply; Liver / cytology; Liver / ultrastructure; Microscopy, Confocal; Microscopy, Electron, Transmission; Models, Anatomic; Oryzias / anatomy & histology
TL;DR:
The investigations show that hepatobiliary architecture in medaka is based on a polyhedral (hexagonal) structural motif, that the intrahepatic biliary system is an interconnected network of canaliculi and bile‐preductules, and that parenchymal architecture in this lower vertebrate is more related to that of the mammalian liver than previously believed.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2007 journal article
Cadmium Ecophysiology in Seven Stonefly (Plecoptera) Species: Delineating Sources and Estimating Susceptibility
Environmental Science & Technology, 41(20), 7171–7177.
MeSH headings : Animals; Cadmium / pharmacokinetics; Cadmium / toxicity; Environmental Pollutants / pharmacokinetics; Environmental Pollutants / toxicity; Insecta / drug effects; Insecta / physiology; Models, Biological; Species Specificity; Subcellular Fractions / metabolism
TL;DR:
Differences in Cd bioaccumulation between the two families were largely driven by differences in dissolved accumulation rates, which were considerably slower in perlodidsthan in perlids and perlodids, and this variability within a phylogenetic context is discussed.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2007 journal article
Rho GTPase signaling directs the late stage morphogenesis of the Xenopus digestive system
Developmental Biology, 306(1), 441.
Source: Crossref
Added: August 28, 2020
2007 journal article
Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala
NeuroImage, 34(3), 905–923.
MeSH headings : Amygdala / cytology; Amygdala / physiology; Animals; Emotions / physiology; Female; Information Storage and Retrieval / methods; Macaca mulatta; Male; Microscopy, Fluorescence / methods; Models, Anatomic; Models, Neurological; Nerve Net / cytology; Nerve Net / physiology; Neural Pathways / cytology; Neural Pathways / physiology; Neurons / cytology; Neurons / physiology; Prefrontal Cortex / cytology; Prefrontal Cortex / physiology
TL;DR:
Investigation of the largely unknown extent and laminar relationship of prefrontal input-output zones linked with the amygdala using neural tracers injected in the amygdala in rhesus monkeys indicates that the connections between prefrontal cortices and the amygdala follow similar patterns as corticocortical connections.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Remote mass spectrometric sampling of electrospray- and desorption electrospray-generated ions using an air ejector
Journal of the American Society for Mass Spectrometry, 18(10), 1844–1847.
MeSH headings : Air; Environmental Monitoring / instrumentation; Equipment Design; Equipment Failure Analysis; Flow Injection Analysis / instrumentation; Flow Injection Analysis / methods; Rheology / instrumentation; Rheology / methods; Robotics / instrumentation; Specimen Handling / instrumentation; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation
TL;DR:
This work demonstrates the remote analysis of a series of analyte ions that range from small molecules and polymers to polypeptides using the AE-LTQ interface and presents preliminary mass spectrometric data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2007 journal article
Pharmacokinetic Modeling of Manganese. II. Hepatic Processing After Ingestion and Inhalation
Journal of Toxicology and Environmental Health, Part A, 70(18), 1505–1514.
MeSH headings : Administration, Inhalation; Administration, Oral; Animals; Intestinal Absorption; Intestinal Mucosa / metabolism; Liver / metabolism; Male; Manganese / pharmacokinetics; Models, Biological; Rats; Rats, Inbred Strains
TL;DR:
Differences in hepatic processing of blood Mn derived from different dose routes need to be accounted for in more complete PK models for Mn that are intended to support human health risk assessments.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Pharmacokinetic Modeling of Manganese. I. Dose Dependencies of Uptake and Elimination
Journal of Toxicology and Environmental Health, Part A, 70(18), 1493–1504.
MeSH headings : Animals; Bile / chemistry; Dose-Response Relationship, Drug; Intestinal Mucosa / metabolism; Liver / metabolism; Male; Manganese / pharmacokinetics; Mice; Models, Biological; Rats; Rats, Inbred Strains
TL;DR:
D dose dependencies in uptake and elimination are necessary inputs for comprehensive PK models guiding human health risk assessments with Mn, and differential control of absorption in single gavage oral dose studies versus continuous high oral doses in the feed is indicated.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Basal Gene Expression in Male and Female Sprague-Dawley Rat Nasal Respiratory and Olfactory Epithelium
Inhalation Toxicology, 19(11), 941–949.
MeSH headings : Animals; Female; Gene Expression Profiling / methods; Gene Expression Regulation / physiology; Male; Nasal Mucosa / metabolism; Nasal Mucosa / physiology; Nasal Mucosa / ultrastructure; Olfactory Mucosa / metabolism; Olfactory Mucosa / physiology; Olfactory Mucosa / ultrastructure; Rats; Rats, Sprague-Dawley; Xenobiotics / metabolism
TL;DR:
To better understand and predict gender differences in response of the nasal epithelium to inhaled xenobiotics, gene expression profiles from naive male and female Sprague-Dawley rats were constructed and surprisingly, there were few gender Differences in gene expression.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Inhibition and recovery of maternal and foetal cholinesterase enzymes following fenitrothion administration in CD rats
Xenobiotica, 37(1), 19–29.
author keywords: toxicology; pharmacokinetics; fenitrothion; neurotoxicity; esterases; rodent
MeSH headings : Animals; Brain / drug effects; Brain / enzymology; Cholinesterase Inhibitors / administration & dosage; Cholinesterase Inhibitors / blood; Cholinesterase Inhibitors / pharmacokinetics; Cholinesterase Inhibitors / pharmacology; Cholinesterases / metabolism; Female; Fenitrothion / administration & dosage; Fenitrothion / blood; Fenitrothion / pharmacokinetics; Fenitrothion / pharmacology; Fetus / drug effects; Fetus / enzymology; Liver / drug effects; Liver / enzymology; Pregnancy; Rats
TL;DR:
Esterase inhibition occurred at a fenitrothion dose that has not been previously associated with reproductive toxicity, suggesting that esterase inhibition should be considered as the critical effect in risk assessments for this pesticide.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Preliminary investigation of changes in the sexually dimorphic nucleus of the rat medial preoptic area following prenatal exposure to fenitrothion
Journal of Applied Toxicology, 27(6), 631–636.
author keywords: anti-androgen; SDN-POA; fenitrothion; developmental neurotoxicity
MeSH headings : Administration, Oral; Androgen Antagonists / administration & dosage; Androgen Antagonists / toxicity; Animals; Body Weight / drug effects; Cholinesterase Inhibitors / administration & dosage; Cholinesterase Inhibitors / toxicity; Dose-Response Relationship, Drug; Female; Fenitrothion / administration & dosage; Fenitrothion / toxicity; Gait / drug effects; Insecticides / administration & dosage; Insecticides / toxicity; Lacrimal Apparatus / drug effects; Lacrimal Apparatus / metabolism; Litter Size / drug effects; Male; Pilot Projects; Pregnancy; Prenatal Exposure Delayed Effects; Preoptic Area / drug effects; Preoptic Area / growth & development; Preoptic Area / pathology; Rats; Sexual Maturation; Tears / metabolism; Tremor / chemically induced
TL;DR:
There was a dose‐related increase in the SDN‐POA volume in males and a dose-related decrease in SDN-POAVolume in females exposed to fenitrothion, suggesting that fen itrothion may have mixed endocrine effects on the developing brain.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2007 journal article
Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation
American Journal of Industrial Medicine, 50(10), 772–778.
author keywords: parkinsonism; neurochemistry; inhalation; macaca mulatta; manganese
MeSH headings : 3,4-Dihydroxyphenylacetic Acid / metabolism; Animals; Basal Ganglia / drug effects; Basal Ganglia / metabolism; Disease Models, Animal; Dopamine / metabolism; Glutamic Acid / metabolism; Hydroxyindoleacetic Acid / metabolism; Inhalation; Macaca mulatta; Manganese Compounds / analysis; Neurotransmitter Agents / analysis; Neurotransmitter Agents / metabolism; Norepinephrine / metabolism; Parkinsonian Disorders / physiopathology; Serotonin / metabolism; Sulfates / analysis; Sulfates / toxicity; gamma-Aminobutyric Acid / metabolism
TL;DR:
Despite the presence of increased tissue manganese concentrations, high-dose exposure to MnSO4 was associated with relatively few changes in basal ganglial neurotransmitter concentrations.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
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