Works Published in 2010
Displaying works 61 - 80 of 209 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans
Clinical Pharmacology & Therapeutics, 88(1), 45–51.
MeSH headings : Acetaminophen / adverse effects; Acetaminophen / metabolism; Acetaminophen / pharmacology; Adolescent; Adult; Alanine Transaminase / blood; Analgesics, Non-Narcotic / adverse effects; Analgesics, Non-Narcotic / metabolism; Analgesics, Non-Narcotic / pharmacology; Biotransformation; Chemical and Drug Induced Liver Injury / diagnosis; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / urine; Cohort Studies; Data Interpretation, Statistical; Female; Humans; Least-Squares Analysis; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Young Adult
TL;DR:
It is demonstrated that the pattern of endogenous metabolites in urine could predict susceptibility to acetaminophen‐induced liver injury in rats, and this “early‐intervention pharmaco‐metabonomics” approach should now be tested in clinical trials of other potentially hepatotoxic drugs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2010 journal article
An approximate Bayesian approach for quantitative trait loci estimation
Computational Statistics & Data Analysis, 54(2), 565–574.
TL;DR:
This paper presents a Bayesian linkage model that offers directly interpretable posterior densities or Bayes factors for linkage, and employs the Laplace approximation for integration over nuisance parameters in backcross (BC) and F2 intercross designs.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Heterotaxin: A novel TGF-beta signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos
Developmental Biology, 344(1), 526.
TL;DR:
A small molecule screen for left-right asymmetry phenotypes in Xenopus embryos is performed and a novel pyridine analog, heterotaxin, is discovered, which disrupts both cardiovascular and digestive organ laterality and inhibits TGF-β-dependent left- right asymmetric gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2010 journal article
Development and environmental application of a genus-specific quantitative PCR approach for Pseudo-nitzschia species
Marine Biology, 157(5), 1161–1169.
TL;DR:
The method developed here quantifies Pseudo-nitzschia spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 28, 2020
2010 journal article
Harmful algae and their potential impacts on desalination operations off southern California
Water Research, 44(2), 385–416.
author keywords: Harmful algal blooms; Desalination; Red tides; Phytoplankton; Phytotoxins
MeSH headings : California; Environmental Monitoring; Eukaryota / growth & development; Eukaryota / pathogenicity; Geography; Harmful Algal Bloom; Marine Toxins / analysis; Marine Toxins / toxicity; Plankton / growth & development; Plankton / pathogenicity; Seawater / chemistry; Water Pollutants / analysis; Water Pollution / statistics & numerical data; Water Purification / methods
TL;DR:
This review identifies the toxic substances, their known producers, and the present state of knowledge regarding the causes of toxic episodes, with a special focus on the Southern California Bight.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: June 28, 2020
2010 journal article
Phylogenetic Affiliations of Mesopelagic Acantharia and Acantharian-like Environmental 18S rRNA Genes off the Southern California Coast
Protist, 161(2), 197–211.
author keywords: 18S rRNA phylogeny; Acantharea; CARD-FISH; deep-sea protist; novel protistan lineage; sarcodine
MeSH headings : California; Cluster Analysis; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Genes, rRNA; In Situ Hybridization, Fluorescence; Molecular Sequence Data; Phylogeny; RNA, Protozoan / genetics; RNA, Ribosomal, 18S / genetics; Rhizaria / genetics; Rhizaria / isolation & purification; Seawater; Sequence Analysis, DNA
TL;DR:
This analysis demonstrated strong support for two branches of unidentified organisms that are closely related to, but possibly distinct from the Acantharea, and found evidence of acantharian sequences from mesopelagic environments branching within the chaunacanthid clade.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 14, 2020
2010 journal article
Temporal Proteomic Analysis Reveals Continuous Impairment of Intestinal Development in Neonatal Piglets with Intrauterine Growth Restriction
Journal of Proteome Research, 9(2), 924–935.
author keywords: Intrauterine growth restriction; Piglets; Intestine; Development; Temporal proteomic analysis; Histological analysis
MeSH headings : Amino Acids / metabolism; Animals; Animals, Newborn; Apoptosis; Energy Metabolism; Fetal Growth Retardation / physiopathology; Homeostasis; Jejunum / embryology; Lipid Metabolism; Mass Spectrometry; Minerals / metabolism; Oxidation-Reduction; Proteome; Swine; Vitamins / metabolism
TL;DR:
The results of the temporal proteomics analysis reveal continuous impairment of intestinal development in neonatal piglets with IUGR and are expected to provide new strategies to improve their survival and growth.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2010 journal article
Differential composition of proteomes in sow colostrum and milk from anterior and posterior mammary glands1
Journal of Animal Science, 88(8), 2657–2664.
author keywords: anterior mammary gland; colostrum; milk; posterior mammary gland; proteome; sow
MeSH headings : Animals; Animals, Suckling / growth & development; Blotting, Western / veterinary; Colostrum / chemistry; Electrophoresis, Gel, Two-Dimensional / veterinary; Female; Mammary Glands, Animal / physiology; Mass Spectrometry / veterinary; Milk / chemistry; Milk Proteins / analysis; Proteome / chemistry; Swine / metabolism
TL;DR:
Investigation of differential proteomes of colostrum and milk secreted by anterior and posterior mammary glands indicates that in comparison with posterior MG, anterior MG are more active in protein synthesis and produce more immunoglobulins and lactoferrin in colostrums and milk.
(via Semantic Scholar)
semanticscholar.org (repository)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2010 chapter
Plasmon-Resonant gold nanorods as multifunctional agents for diagnostics, imaging and photothermal therapy
In Handbook of Materials for Nanomedicine (pp. 585–631).
Contributors: Q. Wei & A. Wei
Source: ORCID
Added: April 10, 2020
2010 journal article
Variation in ultrafiltered and LMW organic matter fluorescence properties under simulated estuarine mixing transects: 2. Mixing with photoexposure
Journal of Geophysical Research, 115.
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 27, 2020
2010 journal article
Erratum: Overview of the brooklyn traffic real-time ambient pollutant penetration and environmental dispersion (B-TRAPPED) study: Theoretical background and model for design of field experiments (Journal of Environmental Monitoring (2009) 11 (2115-2121) DOI: 10.1039/b907123g)
Journal of Environmental Monitoring, 12(12), 2309.
Contributors: I. Hahn, R. Wiener, J. Richmond-Bryant , L. Brixey & S. Henkle
Source: ORCID
Added: January 13, 2020
2010 journal article
MULTIPLE INTERACTING LOCI CONTROL SEX DETERMINATION IN LAKE MALAWI CICHLID FISH
Evolution, 64(2), 486–501.
author keywords: Sex determination; sexually antagonistic selection; speciation
MeSH headings : Animals; Biological Evolution; Cichlids / genetics; Epistasis, Genetic; Female; Genetic Linkage; Malawi; Male; Sex Determination Processes; Sex Ratio
TL;DR:
The inheritance of sex in 19 fish species from the rapidly evolving flock of cichlids in Lake Malawi, Africa is described and it is found that many of these species have a male heterogametic system on linkage group 7.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2010 journal article
Towards monitoring real-time cellular response using an integrated microfluidics-matrix assisted laser desorption ionisation/nanoelectrospray ionisation-ion mobility-mass spectrometry platform
IET Systems Biology, 4(6), 416–427.
Contributors: J. Enders* , C. Marasco*, A. Kole *, B. Nguyen*, S. Sevugarajan*, K. Seale*, J. Wikswo *, J. McLean*
MeSH headings : Cell Biology / instrumentation; Cell Physiological Phenomena; Cell Separation / instrumentation; Cells / chemistry; Cells / cytology; Humans; Jurkat Cells; Microfluidic Analytical Techniques / methods; Saccharomyces cerevisiae; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Systems Biology / methods
TL;DR:
Preliminary experiments examining peptides in methanol and recording the interactions of yeast and Jurkat cells with their superfusate have identified instrumental set-up and control parameters and online desalting procedures that demonstrate and validate this new instrumental platform.
(via Semantic Scholar)
Source: ORCID
Added: December 11, 2019
2010 book
Structurally selective imaging mass spectrometry by imaging ion mobility-mass spectrometry
In Methods in Molecular Biology (Vol. 656, pp. 363–383).
Contributors: J. McLean*, L. Fenn* & J. Enders*
author keywords: Ion mobility; ion mobility-mass spectrometry; IM-MS; imaging mass spectrometry; IMS; MSI; imaging ion mobility-mass spectrometry; structural separations; MALDI; IM-MS/MS
MeSH headings : Diagnostic Imaging / methods; Ions / chemistry; Lipids / chemistry; Mass Spectrometry / methods; Peptides / chemistry; Proteins / chemistry; Tandem Mass Spectrometry
TL;DR:
This chapter describes the utility of structurally based separations combined with imaging mass spectrometry (MS) by ion mobility-MS (IM-MS) approaches and special emphasis is placed on the use of imaging IM-MS for the analysis of samples in life sciences research.
(via Semantic Scholar)
Source: ORCID
Added: December 11, 2019
2010 journal article
Rhinitis Associated with Pesticide Use Among Private Pesticide Applicators in the Agricultural Health Study
Journal of Toxicology and Environmental Health, Part A, 73(20), 1382–1393.
Contributors: R. Slager*, S. Simpson *, T. Levan*, J. Poole *, D. Sandler * & J. Hoppin*
MeSH headings : Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Animals; Captan; Cohort Studies; Diazinon; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Pesticides / adverse effects; Pesticides / classification; Petroleum; Rhinitis / chemically induced; Rhinitis / epidemiology; Risk Factors; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR:
Specific pesticides may contribute to rhinitis in farmers; agricultural activities did not explain these findings.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Thyroid Disease Among Women in the Agricultural Health Study
American Journal of Epidemiology, 171(4), 455–464.
Contributors: W. Goldner, D. Sandler, F. Yu, J. Hoppin* , F. Kamel & T. Levan
author keywords: agriculture; environmental exposure; hyperthyroidism; hypothyroidism; pesticides; thyroid gland
MeSH headings : Agriculture; Cross-Sectional Studies; Environmental Exposure; Female; Fumigation / adverse effects; Fungicides, Industrial / toxicity; Herbicides / toxicity; Humans; Iowa / epidemiology; Logistic Models; North Carolina / epidemiology; Pesticides / toxicity; Prevalence; Prospective Studies; Spouses; Thyroid Diseases / chemically induced; Thyroid Diseases / epidemiology
TL;DR:
Data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Within-person variability in urinary phthalate metabolite concentrations: Measurements from specimens after long-term frozen storage
Journal of Exposure Science and Environmental Epidemiology, 20(2), 169–175.
Contributors: D. Baird*, T. Saldana*, P. Nepomnaschy*, J. Hoppin* , M. Longnecker*, C. Weinberg *, A. Wilcox *
author keywords: biomarker; phthalate; reproducibility; menstrual cycle; temporal variability
MeSH headings : Cryopreservation; Female; Freezing; Humans; Menstrual Cycle; Phthalic Acids / urine; Reference Standards; Reproducibility of Results
TL;DR:
Results suggest that the measurement of phthalate metabolites after long-term sample storage yield generally similar distributions and temporal reliability as those reported for recently collected specimens, and support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence ofphthalate exposures on later outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2010 journal article
Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study
Journal of Exposure Science and Environmental Epidemiology, 20(2), 119–134.
Contributors: K. Thomas *, M. Dosemeci*, J. Hoppin* , L. Sheldon*, C. Croghan*, S. Gordon*, M. Jones *, S. Reynolds*
author keywords: 2,4-D; chlorpyrifos; exposure measurement; farm applicator; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Humans; Skin / chemistry
Source: ORCID
Added: September 13, 2019
2010 journal article
Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study
Cancer Causes & Control, 21(6), 871–877.
Contributors: M. Bonner *, B. Williams *, J. Rusiecki *, A. Blair*, L. Beane Freeman*, J. Hoppin* , M. Dosemeci*, J. Lubin*, D. Sandler *, M. Alavanja*
author keywords: Cancer incidence; Terbufos; Organophosphate insecticides
MeSH headings : Agriculture; Carcinogens; Data Collection; Humans; Incidence; Insecticides; Iowa / epidemiology; Leukemia / complications; Leukemia / epidemiology; Lymphoma, Non-Hodgkin / complications; Lymphoma, Non-Hodgkin / epidemiology; Male; Neoplasms / complications; Neoplasms / epidemiology; Nervous System Neoplasms / complications; Nervous System Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Organophosphorus Compounds; Organothiophosphorus Compounds; Patients; Pesticides; Surveys and Questionnaires
TL;DR:
C cautious interpretation of these results is warranted by the lack of existing experimental and epidemiologic evidence to support carcinogenic effects of terbufos, but suggestive associations between occupational ter bufos use and several cancer sites are found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Myocardial Infarction Incidence Among Farm Women in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 52(7), 693–697.
Contributors: S. Dayton*, D. Sandler *, A. Blair*, M. Alavanja*, L. Beane Freeman* & J. Hoppin*
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; Myocardial Infarction / chemically induced; Myocardial Infarction / epidemiology; North Carolina / epidemiology; Occupational Exposure; Pesticides / adverse effects; Prospective Studies; Risk Factors; Women's Health; Young Adult
TL;DR:
Pesticides may contribute to MI risk among farm women and six of 27 individual pesticides evaluated were significantly associated with nonfatal MI, including chlorpyrifos, coumaphos, carbofuran, metalaxyl, pendimethalin, and trifluralin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
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