Center for Human Health and the Environment

Works Published in 2012

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Displaying works 81 - 100 of 221 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 journal article

IL-17A-mediated STAT6 Independent Mucus Production in Mice

Journal of Allergy and Clinical Immunology, 129(2), AB199.

By: M. Boswell*, D. Newcomb*, K. Goleniewska*, S. Reiss*, K. Adler n & R. Peebles*

Source: Crossref
Added: February 21, 2020

2012 journal article

Tu1855 Tritrichomonas Foetus ADHERE to Intestinal Epithelium by Sialic Acid and Cysteine Protease-Dependent Mechanisms

Gastroenterology, 142(5), S-861-S-862.

By: K. Tolbert & J. Gookin*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 12, 2020

2012 journal article

Mo1784 The In Vivo Transcriptional Response of Intestinal Epithelium to C. Parvum Infection is Dominated by Interferon-Alpha Signaling Pathways

Gastroenterology, 142(5), S-684.

By: D. Foster, D. Nielsen, S. Stauffer & J. Gookin*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 12, 2020

2012 journal article

Air pollution retention within a complex of urban street canyons: A two-city comparison

Atmospheric Environment, 49, 24–32.

By: J. Richmond-Bryant* & A. Reff*

Contributors: J. Richmond-Bryant* & A. Reff*

author keywords: Air quality; Air pollution; Dispersion; Epidemiology; Street canyon; Urban
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Source: ORCID
Added: January 13, 2020

2012 journal article

'Corrigendum to "A literature review of concentrations and size distributions of ambient airborne Pb-containing particulate matter" [Atmos. Environ. 45 (28) (2011) 5005-5015]'

Atmospheric Environment, 60, 680–681.

By: S. Cho, J. Richmond-Bryant*, J. Thornburg, J. Portzer, R. Vanderpool, K. Cavender, J. Rice

Contributors: S. Cho, J. Richmond-Bryant*, J. Thornburg, J. Portzer, R. Vanderpool, K. Cavender, J. Rice

Source: ORCID
Added: January 13, 2020

2012 journal article

Risk of Total and Aggressive Prostate Cancer and Pesticide Use in the Agricultural Health Study

American Journal of Epidemiology, 177(1), 59–74.

By: S. Koutros*, L. Beane Freeman, J. Lubin, S. Heltshe, G. Andreotti, K. Barry, C. DellaValle, J. Hoppin* ...

author keywords: aggressive prostate cancer; cohort study; farming; organophosphate insecticides; pesticide exposure; prostate cancer
MeSH headings : Age Factors; Aged; Agriculture / statistics & numerical data; Health Behavior; Herbicides / toxicity; Humans; Insecticides / toxicity; Male; Middle Aged; Organophosphorus Compounds / toxicity; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / physiopathology; Racial Groups; Severity of Illness Index
TL;DR: This analysis has overcome several limitations of previous studies with the inclusion of a large number of cases with relevant exposure and detailed information on use of specific pesticides at 2 points in time, and for the first time specific pesticides are implicated as risk factors for aggressive prostate cancer. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

Pesticide use and fatal injury among farmers in the Agricultural Health Study

International Archives of Occupational and Environmental Health, 86(2), 177–187.

By: J. Waggoner*, P. Henneberger*, G. Kullman*, D. Umbach*, F. Kamel*, L. Beane Freeman*, M. Alavanja*, D. Sandler*, J. Hoppin*

author keywords: Pesticides; Mortality; Wounds and injuries
MeSH headings : Accidents, Occupational / mortality; Accidents, Occupational / statistics & numerical data; Adult; Aged; Agriculture; Confidence Intervals; Gloves, Protective; Health Surveys; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Pesticides / adverse effects; Proportional Hazards Models; Risk Factors; Surveys and Questionnaires; Time Factors
TL;DR: The association between application of pesticides, particularly certain herbicides, and fatal injuries among farmers should be interpreted cautiously but deserves further evaluation, with particular focus on understanding timing of pesticide use and fatal injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

Seasonal Changes in Patterns of Gene Expression in Avian Song Control Brain Regions

PLoS ONE, 7(4), e35119.

By: C. Thompson*, J. Meitzen*, K. Replogle*, J. Drnevich*, K. Lent*, A. Wissman*, F. Farin*, T. Bammler* ...

Ed(s): S. Yamazaki

MeSH headings : Animals; Brain / metabolism; Breeding; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation; Hormones / blood; Male; Molecular Sequence Annotation; Molecular Sequence Data; Reproducibility of Results; Seasons; Sparrows / genetics; Telencephalon / metabolism; Vocalization, Animal
TL;DR: Changing the hormonal and photoperiodic conditions in seasonally-breeding Gambel's white-crowned sparrows and extracting RNA from the telencephalic song control nuclei reveals categorical differences in the kinds of genes regulated in HVC and RA, and provides insights into the complex molecular pathways that underlie adult neural plasticity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

The Organizational and Aromatization Hypotheses Apply to Rapid, Nonclassical Hormone Action: Neonatal Masculinization Eliminates Rapid Estradiol Action in Female Hippocampal Neurons

Endocrinology, 153(10), 4616–4621.

By: J. Meitzen*, D. Grove* & P. Mermelstein*

MeSH headings : Animals; Aromatase / metabolism; Cells, Cultured; Cyclic AMP Response Element-Binding Protein / metabolism; Dihydrotestosterone / metabolism; Dihydrotestosterone / pharmacology; Estradiol / metabolism; Estradiol / pharmacology; Female; Hippocampus / cytology; Hippocampus / drug effects; Hippocampus / metabolism; Neurons / cytology; Neurons / drug effects; Neurons / metabolism; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate / metabolism; Signal Transduction / drug effects; Testosterone / metabolism; Testosterone / pharmacology
TL;DR: Findings indicate that testosterone aromatization to estradiol leads to a masculinization/defeminization process whereby hippocampal neurons fail to exhibit rapidEstradiol signaling to CREB, extending the organizational and aromatized hypotheses to rapid, nonclassical hormone action. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

A Small Number of Genes Underlie Male Pigmentation Traits in Lake Malawi Cichlid Fishes

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 318(3), 199–208.

By: C. O'Quin, A. Drilea, R. Roberts* & T. Kocher*

MeSH headings : Animals; Cichlids / genetics; Male; Pigmentation / genetics
TL;DR: This work quantified the number of pigment cells on the body and fins of two species of the genus Metriaclima and their hybrids and used the Castle-Wright equation to estimate that differences in individual pigmentation traits between these species are controlled by one to four genes each. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

Origins of Shared Genetic Variation in African Cichlids

Molecular Biology and Evolution, 30(4), 906–917.

author keywords: cichlid; evolution; hybridization; ancestral polymorphism; single nucleotide polymorphism; genetic differentiation
MeSH headings : Adaptation, Biological / genetics; Africa; Animals; Bayes Theorem; Cichlids / genetics; Genetic Loci; Genetic Speciation; Genotype; Lakes; Models, Genetic; Phylogeny; Phylogeography; Polymorphism, Single Nucleotide; Principal Component Analysis; Rivers; Selection, Genetic; Sequence Analysis, DNA
TL;DR: Bayesian and principal component analyses of genetic structure in the data demonstrate that the Lake Malawi endemic flock is not monophyletic and that river species have likely contributed significantly to Malawi genomes, and coalescent simulations support the hypothesis that river cichlids have transported polymorphism between lake assemblages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 journal article

Spatial interactions between organizations and the symbolic landscapes created by their public information campaigns

Water Policy, 15(1), 61–78.

By: B. Cutts*

author keywords: Arizona; Geographic information systems; Information; Phoenix; Public inclusion; Water governance
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2012 entry reference

Multidimensional Separations by Ion Mobility-Mass Spectrometry

By: K. Hines*, J. Enders* & J. McLean*

TL;DR: The unique advantages of IM-MS in biological fields ranging from systems biology to structural biology are introduced, the context of which is introduced by a historical perspective of key advances accomplished over the last century. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 4, 2020

2012 journal article

Target Population Involvement in Urban Ciclovias: A Preliminary Evaluation of St. Louis Open Streets

Journal of Urban Health, 90(6), 1010–1015.

By: J. Hipp*, A. Eyler* & J. Kuhlberg*

author keywords: Ciclovia; Recreation; Health communication; Minority populations
MeSH headings : Adult; Age Factors; Exercise; Female; Health Promotion / organization & administration; Holidays; Humans; Male; Marketing; Missouri; Recreation; Residence Characteristics; Sex Factors; Socioeconomic Factors; Travel
TL;DR: Ciclovias are active street events when roads are open to walkers, cyclists, and families and closed to automobiles and cities must work with residents to increase low-income minority population participation in ciclovia-based physical activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 4, 2020

2012 journal article

A Dual-Column Solid Phase Extraction Strategy for Online Collection and Preparation of Continuously Flowing Effluent Streams for Mass Spectrometry

Analytical Chemistry, 84(20), 8467–8474.

By: J. Enders*, C. Marasco*, J. Wikswo* & J. McLean*

Contributors: J. Enders*, C. Marasco*, J. Wikswo* & J. McLean*

MeSH headings : Bioreactors; Equipment Design; Mass Spectrometry / instrumentation; Microfluidic Analytical Techniques / instrumentation; Salts / isolation & purification; Solid Phase Extraction / instrumentation
TL;DR: This work demonstrates that this dual-column online solid phase extraction (SPE) approach may be used for flow rates as low as 500 nL/min, with temporal resolving power on the order of 3 min, with analyte loadings ranging from femtomoles to picomoles for metabolites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 11, 2019

2012 journal article

Uropathogenic E. coli Promote a Paracellular Urothelial Barrier Defect Characterized by Altered Tight Junction Integrity, Epithelial Cell Sloughing and Cytokine Release

Journal of Comparative Pathology, 147(1), 11–19.

By: M. Wood n, E. Breitschwerdt n, S. Nordone n, K. Linder n & J. Gookin n

author keywords: cytokine; tight junction; urinary tract infection; urothelial permeability
MeSH headings : Animals; Cell Membrane Permeability / physiology; Cytokines / metabolism; Diffusion Chambers, Culture; Dogs; Electric Conductivity; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Epithelial Cells / pathology; Tight Junctions / pathology; Tight Junctions / ultrastructure; Tissue Culture Techniques; Urinary Bladder / metabolism; Urinary Bladder / microbiology; Urinary Bladder / pathology; Uropathogenic Escherichia coli / physiology; Urothelium / metabolism; Urothelium / microbiology; Urothelium / pathology
TL;DR: A potential role for IL-15 is pointed to in UTI-induced urothelial injury after changes in both tissue ultrastructure and TER indicated that uropathogenic E. coli infection promotes a paracellular permeability defect associated with the failure of umbrella cell tight junction formation and umbrella cell sloughing. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 16, 2019

2012 journal article

Proteasome Inhibition of Pathologic Shedding of Enterocytes to Defend Barrier Function Requires X-Linked Inhibitor of Apoptosis Protein and Nuclear Factor κB

Gastroenterology, 143(1), 133–144.e4.

By: D. Foster n, S. Stauffer n, M. Stone n & J. Gookin n

author keywords: Protozoan; Intestine; Parasitic Infection; Cell Death
MeSH headings : Animals; Apoptosis; Caspase 3 / metabolism; Cryptosporidiosis / metabolism; Cryptosporidium parvum; Disease Models, Animal; Enterocytes / metabolism; Enterocytes / microbiology; Ileum / microbiology; Ileum / physiopathology; Intestinal Mucosa / metabolism; NF-kappa B / metabolism; Proteasome Endopeptidase Complex / metabolism; Signal Transduction; Swine; X-Linked Inhibitor of Apoptosis Protein / metabolism
TL;DR: A pathway by which villus epithelial cells are maintained during C parvum infection is identified, which might be used to promote clearance of minimally invasive enteropathogens, such as by increasing the rate of migration of epithelial Cells from the crypt to the villus tip. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: November 16, 2019

2012 journal article

Supplementary material for: Empirical Pathway Analysis, Without Permutation

By: Y. Zhou, W. Barry, F. Wright & C. Hill

Source: ORCID
Added: October 7, 2019

2012 journal article

Simple and accurate trend tests using a permutation approximation

By: Y. Zhou & F. Wright

Source: ORCID
Added: October 7, 2019

2012 journal article

Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model

Toxicological Sciences.

By: E. Lock, N. Abdo, R. Huang, M. Xia, O. Kosyk, S. O’Shea, Y. Zhou, A. Sedykh ...

Source: ORCID
Added: October 7, 2019

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