Works (11)

Updated: July 20th, 2023 21:13

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang n, J. Yu n, Y. Zhang n, X. Zhang*, A. Kahkoska *, G. Chen*, Z. Wang*, W. Sun* ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
Source: Web Of Science
Added: August 19, 2019

2017 journal article

Anaerobe-Inspired Anticancer Nanovesicles

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 56(10), 2588–2593.

By: C. Qian n, P. Feng*, J. Yu n, Y. Chen *, Q. Hu n, W. Sun n, X. Xiao*, X. Hu n ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: drug delivery; nanomedicines; photodynamic therapy
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Cell Death / drug effects; Cell Proliferation / drug effects; Clostridium / chemistry; Clostridium / metabolism; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Hypoxia / metabolism; Imidazoles / chemistry; Imidazoles / pharmacology; Nanoparticles / chemistry; Prodrugs / chemistry; Prodrugs / pharmacology; Salmonella / chemistry; Salmonella / metabolism; Tirapazamine / chemistry; Tirapazamine / pharmacology
Source: Web Of Science
Added: August 6, 2018

2017 review

Conjugated polymer nanomaterials for theranostics

[Review of ]. ACTA PHARMACOLOGICA SINICA, 38(6), 764–781.

By: Q. Cheng-gen  n, Y. Chen *, P. Feng*, X. Xiao*, M. Dong*, J. Yu n, Q. Hu n, Q. Shen *, Z. Gu n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: conjugated polymer; theranostics; biomedical imaging; photodynamic therapy; photothermal therapy; stimuli; responsive drug delivery
MeSH headings : Drug Delivery Systems; Nanostructures / chemistry; Photochemotherapy; Polymers / chemistry; Theranostic Nanomedicine
Source: Web Of Science
Added: August 6, 2018

2017 journal article

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery

ACS NANO, 11(1), 613–620.

By: X. Hu n, J. Yu n, C. Qian n, Y. Lu n, A. Kahkoska *, Z. Xie *, X. Jing*, J. Buse *, Z. Gu n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: drug delivery; vesicles; polymersome; glucose-responsive; insulin; diabetes
MeSH headings : Animals; Diabetes Mellitus, Experimental / chemically induced; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems / methods; Glucose / analysis; Glucose / metabolism; Glucose Oxidase / metabolism; Hydrogen Peroxide / chemistry; Hypoglycemia / drug therapy; Insulin / administration & dosage; Insulin / chemistry; Insulin / pharmacology; Kinetics; Male; Mice; Mice, Inbred C57BL; Polymers / chemical synthesis; Polymers / chemistry; Streptozocin; Transdermal Patch
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

NANO LETTERS, 17(2), 733–739.

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: Drug delivery; diabetes; insulin; glucose-responsive; hypoxia-sensitive; H2O2-sensitive
MeSH headings : Animals; Blood Glucose / metabolism; Cell Hypoxia; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Type 1 / drug therapy; Diabetes Mellitus, Type 1 / metabolism; Drug Carriers / chemistry; Drug Liberation; Glucose / metabolism; Glucose Oxidase / metabolism; HeLa Cells; Humans; Hydrogen Peroxide / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Insulin / administration & dosage; Insulin / chemistry; Male; Mice, Inbred C57BL; Nitroimidazoles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy

ADVANCED MATERIALS, 29(13).

By: Q. Hu n, W. Sun n, C. Qian n, H. Bomba n, H. Xin n & Z. Gu n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Biomimetic Materials / chemistry; Blood Vessels / drug effects; Blood Vessels / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cells, Cultured; Dextrans / chemistry; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice, Nude; Microtubules / enzymology; Microtubules / metabolism; Nanostructures / chemistry; Neoplasm Transplantation; Neoplasms / blood supply; Neoplasms / drug therapy; Neoplasms / metabolism; Oligopeptides / chemistry; Paclitaxel / administration & dosage; Paclitaxel / pharmacokinetics; Tumor Necrosis Factor-alpha / chemistry; Tumor Necrosis Factor-alpha / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018

2016 journal article

ATP-Responsive and Near-Infrared-Emissive Nanocarriers for Anticancer Drug Delivery and Real-Time Imaging

THERANOSTICS, 6(7), 1053–1064.

By: C. Qian*, Y. Chen, S. Zhu, J. Yu*, L. Zhang, P. Feng, X. Tang, Q. Hu* ...

author keywords: drug delivery; nanomedicine; stimuli-responsive; ATP-responsive; theranostics; conjugated polymers
MeSH headings : Adenosine Triphosphate / metabolism; Antineoplastic Agents / administration & dosage; Boronic Acids / metabolism; Doxorubicin / administration & dosage; Drug Carriers / administration & dosage; Hep G2 Cells; Humans; Liver Neoplasms / diagnostic imaging; Liver Neoplasms / drug therapy; Nanoparticles / administration & dosage; Optical Imaging / methods; Theranostic Nanomedicine / methods
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

ADVANCED MATERIALS, 28(43), 9573-+.

By: Q. Hu n, C. Qian n, W. Sun n, J. Wang n, Z. Chen n, H. Bomba n, H. Xin n, Q. Shen *, Z. Gu n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

ADVANCED MATERIALS, 28(17), 3313–3320.

By: C. Qian n, J. Yu n, Y. Chen *, Q. Hu n, X. Xiao*, W. Sun n, C. Wang n, P. Feng*, Q. Shen *, Z. Gu n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Cell Hypoxia; Cell Survival / drug effects; Doxorubicin / chemistry; Doxorubicin / pharmacology; Doxorubicin / therapeutic use; Drug Carriers / chemistry; HeLa Cells; Humans; Hydrogen-Ion Concentration; Light; Mice; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles / chemistry; Neoplasms / diagnostic imaging; Neoplasms / drug therapy; Neoplasms / pathology; Optical Imaging; Polyvinyl Alcohol / chemistry; Singlet Oxygen / chemistry; Singlet Oxygen / metabolism; Transplantation, Heterologous
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Transformable DNA nanocarriers for plasma membrane targeted delivery of cytokine

BIOMATERIALS, 96, 1–10.

By: W. Sun n, W. Ji n, Q. Hu n, J. Yu n, C. Wang n, C. Qian n, G. Hochu n, Z. Gu n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Cancer; Protein delivery; DNA structures; Cytokine; Nanomedicine
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Anticancer Platelet-Mimicking Nanovehicles

ADVANCED MATERIALS, 27(44), 7043-+.

By: Q. Hu n, W. Sun n, C. Qian n, C. Wang n, H. Bomba n & Z. Gu n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Biomimetic Materials / chemistry; Blood Platelets / cytology; Cell Line, Tumor; Cell Membrane / chemistry; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Humans; Intracellular Space / metabolism; Mice; Nanomedicine / methods; Nanostructures / chemistry; TNF-Related Apoptosis-Inducing Ligand / chemistry; TNF-Related Apoptosis-Inducing Ligand / metabolism
Source: Web Of Science
Added: August 6, 2018