Center for Human Health and the Environment

Works Published in 2014

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Displaying works 41 - 60 of 259 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 conference paper

A quantitative sustainability assessment: Effectiveness of green-blue infrastructure in a shrinking city

Cities in Europe, cities in the world: Proceedings of the 12th International Conference on Urban History. Presented at the 12th International Conference on Urban History, Lisbon, Portugal.

By: C. Freixas, P. Fernandez & J. Hipp

Event: 12th International Conference on Urban History at Lisbon, Portugal on September 3-6, 2014

Source: NC State University Libraries
Added: November 3, 2020

2014 chapter

Hooking up with some helminths

In E. A. Stone & C. Dewey (Eds.), Sick! Curious tales of pests and parasites we share with animals (pp. 162–166). Guelph, Ontario: Ontario Veterinary College, University of Guelph.

By: J. Gookin

Ed(s): E. Stone & C. Dewey

Source: NC State University Libraries
Added: October 21, 2020

2014 chapter

Update on treatment of T. foetus and Giardia infections

In J. D. Bonagura & D. C. Twedt (Eds.), Kirk's Current Veterinary Therapy XV (15th ed., p. 528). St. Louis, MO: Elsevier/Saunders.

By: J. Gookin & M. Lappin

Ed(s): J. Bonagura & D. Twedt

Source: NC State University Libraries
Added: October 21, 2020

2014 journal article

Fractional hot deck imputation for robust inference under item nonresponse in survey sampling

Survey Methodology, 40(2), 211–230. https://lib.dr.iastate.edu/stat_las_pubs/116/

By: J. Kim & S. Yang

Source: NC State University Libraries
Added: September 27, 2020

2014 journal article

Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation

Cell, 158(1), 110–120.

MeSH headings : Chromatin / metabolism; Gene Expression Regulation, Fungal; Gene Regulatory Networks; Genes, Reporter; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / chemistry; Saccharomyces cerevisiae Proteins / metabolism; Transcription, Genetic
TL;DR: A synthetic biology approach to decipher the complexity of chromatin regulation by studying emergent transcriptional behaviors from engineered combinatorial, spatial, and temporal patterns of individual CRs. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Loss of estrogen-mediated immunoprotection underlies female gender bias in experimental Crohn’s-like ileitis

Mucosal Immunology, 7(5), 1255–1265.

By: W. Goodman*, R. Garg*, B. Reuter*, B. Mattioli*, E. Rissman* & T. Pizarro*

MeSH headings : Animals; Crohn Disease / drug therapy; Crohn Disease / immunology; Crohn Disease / physiopathology; Disease Models, Animal; Estrogens / pharmacology; Female; Flow Cytometry; Ileitis / drug therapy; Ileitis / physiopathology; Male; Mice; Sex Factors; T-Lymphocytes, Regulatory / drug effects
TL;DR: Hormone signaling influences the expansion and function of GALT Tregs in an ER-dependent manner and contributes to gender-based differences in experimental CD. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Reprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich et al.

Hormones and Behavior, 65(2), 190–193.

By: A. Gore*, J. Balthazart*, D. Bikle*, D. Carpenter*, D. Crews*, P. Czernichow*, E. Diamanti-Kandarakis*, R. Dores* ...

MeSH headings : Animals; Endocrine Disruptors / toxicity; Humans
Source: Crossref
Added: August 28, 2020

2014 journal article

Mouse model systems to study sex chromosome genes and behavior: Relevance to humans

Frontiers in Neuroendocrinology, 35(4), 405–419.

author keywords: Klinefelter syndrome; Turner syndrome; Four core genotypes; Sex differences; Behavior; Sexual differentiation
MeSH headings : Animals; Behavior, Animal / physiology; Disease Models, Animal; Genes, sry / genetics; Humans; Mice; Sex Characteristics; Sex Chromosomes / genetics; Y Chromosome / genetics
TL;DR: It is concluded that many social and cognitive behaviors are modified by sex chromosome complement, and the implications for human research are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2014 journal article

Reprint of: Policy decisions on endocrine disruptors should be based on science across disciplines: A response to Dietrich, et al.

Frontiers in Neuroendocrinology, 35(1), 2–5.

By: A. Gore, J. Balthazart, D. Bikle, D. Carpenter, D. Crews, P. Czernichow, E. Diamanti-Kandarakis, R. Dores ...

Source: Crossref
Added: August 28, 2020

2014 journal article

Dietary phytoestrogens inhibit experimental aneurysm formation in male mice

Journal of Surgical Research, 188(1), 326–338.

author keywords: Phytoestrogen; Aortic aneurysm; Mouse AAA model; Aneurysm phenotype; Inflammatory cytokine; MMP
MeSH headings : Animals; Aorta, Abdominal / metabolism; Aorta, Abdominal / pathology; Aortic Aneurysm, Abdominal / pathology; Aortic Aneurysm, Abdominal / prevention & control; Cytokines / metabolism; Dietary Supplements; Female; Inflammation / diet therapy; Male; Matrix Metalloproteinase 9 / metabolism; Mice; Mice, Inbred C57BL; Phytoestrogens / blood; Phytoestrogens / therapeutic use
TL;DR: The results suggest that dietary phytoestrogens inhibit experimental aortic aneurysm formation in male mice via a reduction of the inflammatory response in the aorta wall. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Do early paternal exposures to lifestyle factors such as smoking increase the risk of chronic diseases in the offspring?

European Journal of Human Genetics, 22(12), 1341–1342.

By: A. Soubry*, G. Verbeke* & C. Hoyo n

MeSH headings : Adiposity; Female; Humans; Male; Paternal Exposure; Puberty; Smoking / adverse effects
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020

2014 journal article

PD31-11 CARBOHYDRATE INTAKE, GLYCEMIC INDEX AND PROSTATE CANCER RISK

Journal of Urology, 191(4S).

By: A. Vidal, C. Williams, E. Allott, L. Howard, D. Grant, M. McPhail, K. Sourbeer, P. Boffetta*, C. Hoyo*, S. Freedland

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2014 journal article

The association between race and prostate cancer risk on initial biopsy in an equal access, multiethnic cohort

Cancer Causes & Control, 25(8), 1029–1035.

By: A. Gaines*, E. Turner*, P. Moorman*, S. Freedland*, C. Keto*, M. McPhail, D. Grant*, A. Vidal*, C. Hoyo*

author keywords: Prostate cancer; Risk; Initial biopsy; Race; Equal access
MeSH headings : Aged; Biopsy, Needle; Black People / statistics & numerical data; Cohort Studies; Health Services Accessibility; Humans; Male; Middle Aged; North Carolina; Prostatic Neoplasms / ethnology; Prostatic Neoplasms / pathology; Retrospective Studies; Veterans / statistics & numerical data; White People / statistics & numerical data
TL;DR: In an equal access healthcare facility, black race was associated with greater risk of PC detection on initial biopsy and of high-grade PC after adjusting for clinical characteristics and mechanisms linking black race and PC risk and PC aggressiveness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2014 journal article

A paternal environmental legacy: Evidence for epigenetic inheritance through the male germ line

BioEssays, 36(4), 359–371.

By: A. Soubry*, C. Hoyo*, R. Jirtle* & S. Murphy*

author keywords: developmental origins of health and disease (DOHaD); environment; epigenetics; imprinted genes; offspring; paternal exposures; spermatogenesis; transgenerational effects
MeSH headings : Animals; DNA Methylation; Diet; Epigenesis, Genetic; Gene-Environment Interaction; Genomic Imprinting; Histones / metabolism; Humans; Life Style; Male; Obesity / genetics; Paternal Exposure; RNA, Untranslated; Radiation, Ionizing; Spermatogenesis / physiology; Spermatozoa / physiology; Zygote
TL;DR: This essay suggests the existence of epigenetic windows of susceptibility to environmental insults during sperm development and suggests changes in DNA methylation, histone modification, and non‐coding RNAs are viable mechanistic candidates for a non‐genetic transfer of paternal environmental information, from maturing germ cell to zygote. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

The American Journal of Human Genetics, 94(2), 233–245.

By: L. Lange, Y. Hu, H. Zhang, C. Xue, E. Schmidt, Z. Tang, C. Bizon, E. Lange ...

MeSH headings : Adult; Aged; Apolipoproteins E / blood; Apolipoproteins E / genetics; Cholesterol, LDL / genetics; Cohort Studies; Dyslipidemias / blood; Dyslipidemias / genetics; Exome; Female; Follow-Up Studies; Gene Frequency; Genetic Code; Genome-Wide Association Study; Genotype; Humans; Lipase / genetics; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Proprotein Convertase 9; Proprotein Convertases / genetics; Receptors, LDL / genetics; Sequence Analysis, DNA; Serine Endopeptidases / genetics
TL;DR: This large whole-exome-sequencing study for LDL-C identified a gene not known to be implicated in LDL- C and provides unique insight into the design and analysis of similar experiments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2014 journal article

Bisphenol A and cardiometabolic risk factors in obese children

Science of The Total Environment, 470-471, 726–732.

Contributors: N. Khalil*, J. Ebert*, L. Wang*, S. Belcher*, M. Lee*, S. Czerwinski*, K. Kannan*

author keywords: Bisphenol A; Endocrine disruptor; Non-monotonic dose response; Childhood obesity; Nonalcoholic fatty liver disease; Spline analysis
MeSH headings : Anthropometry; Aspartate Aminotransferases / blood; Benzhydryl Compounds / blood; Body Mass Index; Child; Endocrine Disruptors / blood; Fatty Liver / blood; Fatty Liver / epidemiology; Female; Humans; Insulin Resistance; Male; Non-alcoholic Fatty Liver Disease; Obesity / blood; Obesity / epidemiology; Ohio / epidemiology; Phenols / blood; Risk Factors
TL;DR: Urinary BPA in obese children, at least in males is associated with adverse liver and metabolic effects, and high diastolic blood pressure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2014 journal article

Classical nuclear hormone receptor activity as a mediator of complex concentration response relationships for endocrine active compounds

Current Opinion in Pharmacology, 19, 112–119.

By: C. Cookman & S. Belcher*

Contributors: C. Cookman & S. Belcher*

MeSH headings : Animals; Cell Survival / drug effects; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Humans; Receptors, Cytoplasmic and Nuclear / metabolism
TL;DR: Evidence suggests that ligand selectivity, activation of multiple molecular targets, concerted regulation of multiple opposing endpoints, and multiple ligand binding sites within nuclear receptors also contribute to nonmonotonic concentration response relationships of endocrine active ligands. (via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2014 journal article

Solution-state conformation and stoichiometry of yeast Sir3 heterochromatin fibres

Nature Communications, 5(1).

MeSH headings : Algorithms; Heterochromatin / chemistry; Heterochromatin / metabolism; Microscopy, Atomic Force; Monte Carlo Method; Nucleosomes / chemistry; Nucleosomes / genetics; Nucleosomes / metabolism; Protein Multimerization; Silent Information Regulator Proteins, Saccharomyces cerevisiae / chemistry; Silent Information Regulator Proteins, Saccharomyces cerevisiae / genetics; Silent Information Regulator Proteins, Saccharomyces cerevisiae / metabolism; Ultracentrifugation
TL;DR: Sygert et al. show that Sir3 - a key factor in the formation of heterochromatin - promotes a chromatin structure distinct from the canonical 30 nm fibre. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Zebrafish: A Marvel of High-Throughput Biology for 21st Century Toxicology

Current Environmental Health Reports, 1(4), 341–352.

By: S. Bugel*, R. Tanguay* & A. Planchart n

TL;DR: Advances in automation, high-throughput screening, and analysis that leverage the power of the zebrafish embryo model for unparalleled advances in the authors' understanding of how chemicals in their environment affect their health and wellbeing are highlighted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2014 conference paper

Empirical Acceptance-Resistance Agent-Based Modeling Approach for Simulating the Adoption of Water Reuse

World Environmental and Water Resources Congress 2014. Presented at the World Environmental and Water Resources Congress 2014.

By: V. Kandiah n, E. Berglund n & A. Binder n

Event: World Environmental and Water Resources Congress 2014

Sources: Crossref, NC State University Libraries
Added: June 6, 2020

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