Works Published in 2017
Displaying works 41 - 60 of 321 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment†
Biology of Reproduction, 96(2), 313–326.
author keywords: progesterone receptor; implantation; uterine receptivity; progesterone signaling; mouse models
MeSH headings : Alleles; Animals; Cloning, Molecular; Down-Regulation; Embryo Implantation; Endometrium; Female; Gene Expression Regulation / physiology; Hedgehog Proteins / genetics; Hedgehog Proteins / metabolism; Male; Mice, Transgenic; Progesterone / metabolism; Receptors, OSM-LIF / genetics; Receptors, OSM-LIF / metabolism; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism; Wnt Proteins / genetics; Wnt Proteins / metabolism
TL;DR:
Downregulation of the PGRA isoform at the window of receptivity is necessary for the attenuation of hedgehog signaling, transcriptional activation of LIF signaling, and modulation of solutes and fluid, producing a receptive environment for the attaching embryo.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2017 journal article
Decidualisation and placentation defects are a major cause of age-related reproductive decline
Nature Communications, 8(1).
MeSH headings : Age Factors; Aging / genetics; Aging / physiology; Animals; Cells, Cultured; Decidua / metabolism; Decidua / physiopathology; Embryonic Development / genetics; Embryonic Development / physiology; Female; Gene Expression Profiling / methods; Humans; Male; Maternal Age; Mice, Inbred C57BL; Placenta / metabolism; Placenta / physiopathology; Placentation / genetics; Pregnancy; Pregnancy Complications / genetics; Pregnancy Complications / physiopathology; Reproduction / genetics; Reproduction / physiology; Uterus / metabolism; Uterus / physiopathology
TL;DR:
It is reported that abnormal embryonic development in aged female mice is associated with severe placentation defects, which result from major deficits in the decidualisation response of the uterine stroma, and rescued by transferring the embryo from an old to a young uterus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2017 chapter
Delivery of Morpholino Antisense Oligonucleotides to a Developing Ovine Conceptus via Luminal Injection into a Ligated Uterine Horn
In Morpholino Oligomers (pp. 241–250).
author keywords: Ovine; Conceptus; Peri-implantation; Uterine ligation; Morpholino antisense oligonucleotide; Endo-Porter
MeSH headings : Animals; Embryonic Development / genetics; Female; Gene Transfer Techniques; Morpholinos / administration & dosage; Morpholinos / genetics; Oligonucleotides, Antisense; Peptides; Uterus
TL;DR:
The method for preparation and surgical delivery of MAO-Endo-Porter complex to developing ovine conceptus on day 8 postmating is described and methods for posttreatment sample recovery on day 16 postmated are outlined.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2017 journal article
Hormone dependent uterine epithelial-stromal communication for pregnancy support
Placenta, 60, S20–S26.
author keywords: Progesterone; Pregnancy; Uterine receptivity
MeSH headings : Animals; Biomedical Research / methods; Biomedical Research / trends; Cell Communication; Cell Transdifferentiation; Embryo Implantation; Endometrium / cytology; Endometrium / physiology; Estrogens / metabolism; Estrogens / physiology; Female; Humans; Ovary / metabolism; Ovary / physiology; Pregnancy; Progesterone / metabolism; Progesterone / physiology; Stromal Cells / cytology; Stromal Cells / physiology; Uterus / cytology; Uterus / physiology
TL;DR:
The molecular mechanisms utilized by steroid hormones that regulate uterine receptivity, as well as the major hormones governing these processes, are discussed, to establish and maintain pregnancy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2017 journal article
Walking the DNA Methylation Tightrope: The Involvement of Intrinsically Disordered Regions of Transcription Factors
Biophysical Journal, 112(3), 207a.
TL;DR:
Data reveals how MBD2 dynamically achieves DNA binding specificity for methylated DNA and supports that the IDR ofMBD2 modulates MBD 2-binding dynamics, and is important for further deciphering the molecular mechanisms of MBD and mCpG epigenetic regulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2017 journal article
Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair
Biophysical Journal, 112(3), 7a.
TL;DR:
How AFM, DREEM, and single-molecule fluorescence can be powerful tools to study the stoichiometries, conformations, and dynamic assembly of multi-component complexes is discussed.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2017 journal article
How predictable is plastic damage at the atomic scale?
Applied Physics Letters, 110(9), 091902.
TL;DR:
This work combines image analysis with molecular dynamics simulation to quantify similarities between atomic structures of plastic damage in a database of strained copper bi-crystals, and shows that a manifold of different outcomes can originate ostensibly from the same initial structure.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2017 journal article
Correlating Local Chemistry and Local Cation Displacements in the Relaxor Ferroelectric PMN
Microscopy and Microanalysis, 23(S1), 1616–1617.
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2017 journal article
Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain
Veterinary Immunology and Immunopathology, 183, 49–59.
author keywords: Biomarker; Immunoassay; Multiplex; Arthritis
MeSH headings : Animals; Cat Diseases / blood; Cat Diseases / physiopathology; Cats; Cytokines / blood; Female; Male; Osteoarthritis / blood; Osteoarthritis / diagnostic imaging; Osteoarthritis / physiopathology; Osteoarthritis / veterinary; Pain / veterinary; Radiography / veterinary
TL;DR:
Evaluating the concentration of cytokines and chemokines in serum samples obtained from cats with and without degenerative joint disease and associated pain showed that cats with higher radiographic degenerative joints disease scores have higher serum concentrations of IL-4 and IL-8, while Cats with higher orthopedic exam pain scores haveHigher concentrations ofIL-8.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Source: Crossref
Added: February 24, 2020
2017 journal article
A Powerful Test for SNP Effects on Multivariate Binary Outcomes Using Kernel Machine Regression
Statistics in Biosciences, 10(1), 117–138.
author keywords: Correlated binary responses; Generalized estimating equations; IBS kernel; Kernel machine; Non-parametric regression
TL;DR:
A score-based test using a non-parametric modeling framework that jointly models the global effect of the marker set and accounts for the non-linear effects and potentially complicated interaction between markers using reproducing kernels is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 21, 2020
2017 journal article
MSiReader v1.0: Evolving Open-Source Mass Spectrometry Imaging Software for Targeted and Untargeted Analyses
Journal of The American Society for Mass Spectrometry, 29(1), 8–16.
author keywords: Mass spectrometry imaging; Mass spectrometry software; Data analysis; Image processing; High mass resolving power; Open-source; Orbitrap
TL;DR:
A major update to the mass spectrometry imaging (MSI) software MSiReader is presented, offering a multitude of newly added features critical to MSI analyses, enabling the MSI community to evaluate their data in greater depth and in less time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2017 journal article
IR-MALDESI Mass Spectrometry Imaging at 50 Micron Spatial Resolution
Journal of The American Society for Mass Spectrometry, 28(10), 2099–2107.
author keywords: Mass spectrometry imaging; IR-MALDESI; Tissue imaging; Spatial resolution; Laser focusing
TL;DR:
This work presents MSI using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) at 50 μm resolution, using an adjustable iris, beam expander, and an aspherical focusing lens to reduce tissue ablation diameters for MSI at high resolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2017 journal article
The scope of Analytical and Bioanalytical Chemistry (ABC)
Analytical and Bioanalytical Chemistry, 410(3), 649–650.
TL;DR:
Assessing whether an application is within the scope of Analytical and Bioanalytical Chemistry, it is recommended that authors consider whether the major focus of the manuscript is to advance another field and whether the work demonstrates an innovative contribution to the field.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2017 journal article
Cover Image
Rapid Communications in Mass Spectrometry, 31(22), i-i.
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2017 journal article
Regulation of cytokinesis during corticogenesis: focus on the midbody
FEBS Letters, 591(24), 4009–4026.
author keywords: abscission; asymmetric; cell division; corticogenesis; cytokinesis; midbody; neurogenesis; symmetric
MeSH headings : Animals; Body Patterning / physiology; Cell Differentiation / physiology; Cell Division / physiology; Cell Movement / physiology; Cerebral Cortex / cytology; Cerebral Cortex / embryology; Cytokinesis / physiology; Humans; Neural Stem Cells / cytology; Neural Stem Cells / physiology; Neurogenesis / physiology
TL;DR:
This review describes the midbody and its constituent proteins, as well as the known consequences of their manipulation during cortical development, and the potential functional relevance of midbody mechanisms is discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 21, 2020
2017 journal article
Cover Image, Volume 73, Issue 3
Pest Management Science, 73(3), i-i.
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2017 journal article
Changes in vaginal community state types reflect major shifts in the microbiome
Microbial Ecology in Health and Disease, 28(1), 1303265.
TL;DR:
The results show that the CST concept is useful for studying microbiome dynamics, with healthy subjects persist in a CST for two to three weeks or more on average, while those with evidence of dysbiosis tend to change more often.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: Crossref
Added: February 5, 2020
2017 journal article
The impact of rare variation on gene expression across tissues
Nature, 550(7675), 239–243.
MeSH headings : Bayes Theorem; Female; Gene Expression Profiling; Genetic Variation / genetics; Genome, Human / genetics; Genomics; Genotype; Humans; Male; Models, Genetic; Organ Specificity / genetics; Sequence Analysis, RNA
TL;DR:
It is demonstrated that rare variants contribute to large gene expression changes across tissues and provide an integrative method for interpretation of rare variants in individual genomes.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2017 journal article
Dynamic landscape and regulation of RNA editing in mammals
Nature, 550(7675), 249–254.
MeSH headings : Adenosine Deaminase / genetics; Adenosine Deaminase / metabolism; Animals; Female; Genotype; HEK293 Cells; Humans; Male; Mice; Muscles / metabolism; Nuclear Proteins / metabolism; Organ Specificity / genetics; Primates / genetics; Proteolysis; RNA Editing / genetics; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Spatio-Temporal Analysis; Species Specificity; Transcriptome / genetics
TL;DR:
This work curated an extensive set of ADAR1 and ADAR2 targets and showed that many editing sites display distinct tissue-specific regulation by the ADAR enzymes in vivo, suggesting stronger cis-directed regulation of RNA editing for most sites, although the small set of conserved coding sites is under stronger trans-regulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
2017 journal article
A Two-Stage Hidden Markov Model Design for Biomarker Detection, with Application to Microbiome Research
Statistics in Biosciences, 10(1), 41–58.
author keywords: Biomarker; False discovery rates; Hidden Markov model; Metagenomics; Metatranscriptomics; PCR
TL;DR:
This paper studies an efficient HMM–FDR-based two-stage design, using a simple integrated analysis procedure across the stages, and proposes a power analysis method that shows excellent performance when compared to available methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 25, 2020
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.