Center for Human Health and the Environment

Works Published in 2006

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Displaying works 61 - 80 of 134 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2006 journal article

Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants

Journal of Exposure Science and Environmental Epidemiology, 16(1), 39–48.

Contributors: J. Hoppin*, R. Ulmer*, A. Calafat*, D. Barr*, S. Baker*, H. Meltzer*, K. Rønningen*

Source: ORCID
Added: September 13, 2019

2006 journal article

Pesticides associated with Wheeze among Commercial Pesticide Applicators in the Agricultural Health Study

American Journal of Epidemiology, 163(12), 1129–1137.

By: J. Hoppin*, D. Umbach, S. London, C. Lynch, M. Alavanja & D. Sandler

Contributors: J. Hoppin*, D. Umbach, S. London, C. Lynch, M. Alavanja & D. Sandler

author keywords: agriculture; insecticides; occupational exposure; organophosphates; pesticides; signs and symptoms; respiratory; sulfonylurea compounds
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Cross-Sectional Studies; Dose-Response Relationship, Drug; Female; Humans; Iowa / epidemiology; Male; Middle Aged; Occupational Exposure / adverse effects; Organophosphorus Compounds / adverse effects; Pesticides / adverse effects; Pyrimidines / adverse effects; Respiratory Sounds; Risk Factors; Sulfonylurea Compounds / adverse effects
TL;DR: The results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Fertility and exposure to solvents among families in the Agricultural Health Study

Occupational and Environmental Medicine, 63(7), 469–475.

By: M. Sallmén*, D. Baird, J. Hoppin*, A. Blair & D. Sandler

Contributors: M. Sallmén*, D. Baird, J. Hoppin*, A. Blair & D. Sandler

MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Cross-Sectional Studies; Female; Finland; Humans; Infertility / chemically induced; Male; Middle Aged; Occupational Exposure / adverse effects; Odds Ratio; Regression Analysis; Risk Factors; Solvents / toxicity
TL;DR: Investigating the impact of solvent exposure on subfertility among families of male licensed pesticide applicators in the Agricultural Health Study cohort found solvents may impair fertility of either gender, though the evidence for female effects is stronger than for male effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Phorate Exposure and Incidence of Cancer in the Agricultural Health Study

Environmental Health Perspectives, 114(8), 1205–1209.

By: R. Mahajan*, M. Bonner*, J. Hoppin* & M. Alavanja*

Contributors: R. Mahajan*, M. Bonner*, J. Hoppin* & M. Alavanja*

author keywords: agriculture; insecticides; neoplasms; occupational exposure; organophosphorus compounds; organothiophosphorus compounds; pesticides; prostate; phorate
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Alcohol Drinking / epidemiology; Cohort Studies; Follow-Up Studies; Humans; Insecticides / adverse effects; Insecticides / analysis; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Phorate / adverse effects; Phorate / analysis; Prostatic Neoplasms / epidemiology; Socioeconomic Factors; Surveys and Questionnaires; Zea mays
TL;DR: The observed statistical interaction suggests a gene–environment interaction between family history and phorate exposure in the incidence of prostate cancer, but other explanations are also possible. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Pesticides and Adult Respiratory Outcomes in the Agricultural Health Study

Annals of the New York Academy of Sciences, 1076(1), 343–354.

Contributors: J. Hoppin*, D. Umbach*, S. London*, C. Lynch*, M. Alavanja* & D. Sandler*

author keywords: farmers; occupational exposure; organophosphates; pesticide applicators
MeSH headings : Adult; Agriculture; Animals; Female; Humans; Male; Middle Aged; Pesticides / toxicity; Respiratory Tract Diseases / chemically induced
TL;DR: The results of the wheeze study are consistent with recent animal models that support a role for organophosphates and respiratory outcomes, and are also consistent with the results of previous studies on grain and animal exposures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Reduced Fertility Among Overweight and Obese Men

Epidemiology, 17(5), 520–523.

By: M. Sallm??n, D. Sandler, J. Hoppin*, A. Blair & D. Baird

Contributors: M. Sallmén, D. Sandler, J. Hoppin*, A. Blair & D. Baird

MeSH headings : Adult; Agriculture / statistics & numerical data; Body Mass Index; Epidemiologic Studies; Humans; Infertility, Male / epidemiology; Infertility, Male / etiology; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Obesity / epidemiology; Odds Ratio; United States / epidemiology
TL;DR: There was a dose–response relationship, and the BMI effect was stronger when the data were limited to couples with the highest-quality infertility data, suggesting that erectile dysfunction in older men does not explain the association. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Fonofos Exposure and Cancer Incidence in the Agricultural Health Study

Environmental Health Perspectives, 114(12), 1838–1842.

By: R. Mahajan*, A. Blair*, C. Lynch*, P. Schroeder*, J. Hoppin*, D. Sandler*, M. Alavanja*

Contributors: R. Mahajan*, A. Blair*, C. Lynch*, P. Schroeder*, J. Hoppin*, D. Sandler*, M. Alavanja*

author keywords: agriculture; fonofos; insecticides; neoplasms; occupational exposure; organophosphorus compounds; organothiophosphorus compounds; pesticides
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Cohort Studies; Family Health; Female; Fonofos / analysis; Fonofos / poisoning; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Neoplasms / genetics; North Carolina / epidemiology; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Exposure / statistics & numerical data; Organophosphate Poisoning; Organophosphorus Compounds / analysis; Organothiophosphorus Compounds / analysis; Organothiophosphorus Compounds / poisoning; Pesticides / analysis; Pesticides / poisoning; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Prostatic Neoplasms / genetics; Regression Analysis; Risk Factors; Surveys and Questionnaires
TL;DR: Although prostate cancer risk was unrelated to fonofos use overall, among applicators with a family history of prostate cancer, the authors observed a significant dose–response trend for lifetime exposure-days, a measure that takes into account factors that modify pesticide exposure. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Environmental Exposure Assessment of Pesticides in Farmworker Homes

Environmental Health Perspectives, 114(6), 929–935.

By: J. Hoppin*, J. Adgate*, M. Eberhart*, M. Nishioka* & P. Ryan*

Contributors: J. Hoppin*, J. Adgate*, M. Eberhart*, M. Nishioka* & P. Ryan*

author keywords: dust sampling; fiarmworkers; pesticides
MeSH headings : Agriculture; Environmental Exposure; Family; Food Analysis; Food Contamination; Humans; Pesticides / toxicity; Population Surveillance; Water Supply / analysis
TL;DR: This mini-monograph discusses the strategies used to assess pesticide exposures, presents limitations in the available data for farmworkers, and suggests research needs for future studies of pesticide exposure among farmworker families. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Farmworker Exposure to Pesticides: Methodologic Issues for the Collection of Comparable Data

Environmental Health Perspectives, 114(6), 923–928.

author keywords: biomonitoring; data collection; environmental assessment; farmworker; health outcomes; pesticide exposure
MeSH headings : Agriculture; Biomarkers; Data Collection / methods; Data Collection / standards; Humans; Occupational Exposure; Pesticides / toxicity
TL;DR: The Farmworker Pesticide Exposure Comparable Data Conference assembled 25 scientists from diverse disciplinary and organizational backgrounds to develop methodologic consensus in four areas of farmworker pesticide exposure research: environmental exposure assessment, biomarkers, personal and occupational predictors of exposure, and health outcomes of exposure. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study

International Journal of Cancer, 118(12), 3118–3123.

By: J. Rusiecki*, L. Hou*, W. Lee*, A. Blair*, M. Dosemeci*, J. Lubin*, M. Bonner*, C. Samanic* ...

Contributors: J. Rusiecki*, L. Hou*, W. Lee*, A. Blair*, M. Dosemeci*, J. Lubin*, M. Bonner*, C. Samanic* ...

author keywords: metolachlor; cancer; pesticides; herbicides; applicators
MeSH headings : Acetamides / adverse effects; Adult; Colonic Neoplasms / epidemiology; Colonic Neoplasms / etiology; Female; Follow-Up Studies; Hematologic Neoplasms / epidemiology; Hematologic Neoplasms / etiology; Herbicides / adverse effects; Humans; Incidence; Iowa / epidemiology; Life Style; Lung Neoplasms / epidemiology; Lung Neoplasms / etiology; Male; Middle Aged; Mouth Neoplasms / epidemiology; Mouth Neoplasms / etiology; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Registries; Risk Assessment; Risk Factors; Surveys and Questionnaires
TL;DR: Evaluated the incidence of cancer among pesticide applicators exposed to metolachlor in the Agricultural Health Study, a prospective cohort study of licensed pesticides applicators in Iowa and North Carolina, finding no clear risk for any cancer subtype for exposure to metlachlor. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Cancer Incidence among Pesticide Applicators Exposed to Cyanazine in theAgricultural Health Study

Environmental Health Perspectives, 114(8), 1248–1252.

By: S. Lynch*, J. Rusiecki*, A. Blair*, M. Dosemeci*, J. Lubin*, D. Sandler*, J. Hoppin*, C. Lynch*, M. Alavanja*

Contributors: S. Lynch*, J. Rusiecki*, A. Blair*, M. Dosemeci*, J. Lubin*, D. Sandler*, J. Hoppin*, C. Lynch*, M. Alavanja*

author keywords: Agricultural Health Study; cancer; cyanazine; farming; herbicide; pesticides; triazine herbicide
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Cohort Studies; Colonic Neoplasms / epidemiology; Female; Follow-Up Studies; Hematologic Neoplasms / epidemiology; Herbicides / adverse effects; Humans; Lung Neoplasms / epidemiology; Lymphoma / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Poisson Distribution; Prospective Studies; Prostatic Neoplasms / epidemiology; Risk Assessment; Triazines / adverse effects
TL;DR: It was found that there were no clear, consistent associations between cyanazine exposure and any cancer analyzed, and the number of sites was small for certain cancers, limiting any conclusion with regard to ovarian, breast, and some other cancers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Cancer Incidence among Pesticide Applicators Exposed to Dicamba in the Agricultural Health Study

Environmental Health Perspectives, 114(10), 1521–1526.

By: C. Samanic*, J. Rusiecki*, M. Dosemeci*, L. Hou*, J. Hoppin*, D. Sandler*, J. Lubin*, A. Blair*, M. Alavanja*

Contributors: C. Samanic*, J. Rusiecki*, M. Dosemeci*, L. Hou*, J. Hoppin*, D. Sandler*, J. Lubin*, A. Blair*, M. Alavanja*

author keywords: cancer incidence; farming; neoplasms; pesticides; United States
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Dicamba / toxicity; Humans; Incidence; Middle Aged; Neoplasms / chemically induced; Neoplasms / classification; Neoplasms / epidemiology; North Carolina / epidemiology; Pesticides / toxicity; Registries
TL;DR: Associations between exposure and lung and colon cancer were observed, but clear evidence for an association between dicamba exposure and cancer risk was not found. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Depression and Pesticide Exposures in Female Spouses of Licensed Pesticide Applicators in the Agricultural Health Study Cohort

Journal of Occupational and Environmental Medicine, 48(10), 1005–1013.

By: C. Beseler*, L. Stallones*, J. Hoppin*, M. Alavanja*, A. Blair*, T. Keefe*, F. Kamel*

Contributors: C. Beseler*, L. Stallones*, J. Hoppin*, M. Alavanja*, A. Blair*, T. Keefe*, F. Kamel*

MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / psychology; Agrochemicals / toxicity; Case-Control Studies; Depression / chemically induced; Depression / epidemiology; Environmental Exposure / adverse effects; Female; Health Surveys; Humans; Iowa / epidemiology; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pesticides / toxicity; Risk Factors; Spouses
TL;DR: Pesticide poisoning may contribute to risk of depression among women who had physician-diagnosed depression requiring medication and lifetime pesticide use was categorized as never mixed/applied pesticides, low exposure, high exposure, and a history of diagnosed pesticide poisoning. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Causes of Mortality and Risk Factors for Injury Mortality Among Children in the Agricultural Health Study

Journal of Agromedicine, 11(3-4), 47–59.

By: K. Flower*, J. Hoppin*, D. Shore, C. Lynch*, A. Blair*, C. Knott*, M. Alavanja*, D. Sandler*

Contributors: K. Flower*, J. Hoppin*, D. Shore, C. Lynch*, A. Blair*, C. Knott*, M. Alavanja*, D. Sandler*

TL;DR: Parent and child characteristics associated with child injury mortality could be used to target farm safety interventions in Iowa and North Carolina between 1975 and 1998. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2006 journal article

Neonatal genistein or bisphenol-A exposure alters sexual differentiation of the AVPV☆

Neurotoxicology and Teratology, 28(1), 111–118.

By: H. Patisaul*, A. Fortino & E. Polston

author keywords: phytoestrogens; ER alpha; tyrosine hydroxylase; rat; development; hypothalamus
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds; Cell Count; Cell Differentiation / drug effects; Cell Differentiation / physiology; Disease Models, Animal; Estradiol / metabolism; Estradiol / pharmacology; Estradiol Congeners / toxicity; Estrogen Receptor alpha / drug effects; Estrogen Receptor alpha / metabolism; Estrogens, Non-Steroidal / adverse effects; Female; Genistein / toxicity; Growth Inhibitors / toxicity; Male; Nervous System Malformations / chemically induced; Nervous System Malformations / pathology; Nervous System Malformations / physiopathology; Phenols / toxicity; Pregnancy; Preoptic Area / abnormalities; Preoptic Area / drug effects; Preoptic Area / physiopathology; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Differentiation / drug effects; Sex Differentiation / physiology; Tyrosine 3-Monooxygenase / drug effects; Tyrosine 3-Monooxygenase / metabolism
TL;DR: It is hypothesized that exposure to EACs during this critical period could alter the sexually dimorphic expression of TH and the overall expression of estrogen receptor alpha (ERalpha) in the AVPV and identified a population of neurons co-expressing TH and ERalpha located primarily in the medial region of the A VPV. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019

2006 journal article

The Comparative Toxicogenomics Database: A Cross-Species Resource for Building Chemical-Gene Interaction Networks

Toxicological Sciences, 92(2), 587–595.

By: C. Mattingly*, M. Rosenstein, A. Davis, G. Colby, J. Forrest & J. Boyer

author keywords: CTD; chemicals; environment; GO; toxicology; pathways; interactions
MeSH headings : Animals; Databases, Factual; Environmental Health; Humans; Toxicogenetics
TL;DR: New CTD features include integrated cross-links to microarray data from chemicals, genes, and sequences in CTD, a reference set related to chemical-gene and protein interactions identified by an information retrieval system, and a "Chemicals in the News" initiative that provides links from CTD chemicals to environmental health articles from the popular press. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019

2006 journal article

The Comparative Toxicogenomics Database (CTD): a resource for comparative toxicological studies

Journal of Experimental Zoology Part A: Comparative Experimental Biology, 305A(9), 689–692.

By: C. Mattingly*, M. Rosenstein*, G. Colby*, J. Forrest Jr & J. Boyer*

MeSH headings : Animals; Databases, Factual; Humans; Toxicogenetics; Xenobiotics / toxicity
TL;DR: The publicly available Comparative Toxicogenomics Database (CTD) is developed to promote understanding about the effects of environmental chemicals on human health and identifies interactions between chemicals and genes and facilitates cross-species comparative studies of these genes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019

2006 journal article

The role of neuregulin-ErbB4 interactions on the proliferation and organization of cells in the subventricular zone

Proceedings of the National Academy of Sciences, 103(6), 1930–1935.

author keywords: adult neurogenesis; rostral migratory stream; schizophrenia
MeSH headings : Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Enzyme Activation; ErbB Receptors / deficiency; ErbB Receptors / genetics; ErbB Receptors / metabolism; Ligands; Mice; Neuregulins / metabolism; Olfactory Bulb / cytology; Olfactory Bulb / metabolism; Prosencephalon / cytology; Prosencephalon / metabolism; Protein Binding; Receptor, ErbB-4; Time Factors
TL;DR: NRG2 is identified as a factor capable of promoting SVZ proliferation, leading to the formation of new neurons in vivo, indicating that different NRG ligands affect distinct populations of differentiating neural precursors in the neurogenic regions of the mature forebrain. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

2006 journal article

Conditional Transgene and Gene Targeting Methodologies in Zebrafish

Zebrafish, 3(4), 415–429.

By: A. Deiters n & J. Yoder n

TL;DR: The focus of this review is to summarize the pros and cons of the currently available systems for functional genomics in zebrafish, and to discuss the need for future methodologies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2006 journal article

Potential therapy for mucus hypersecretion in chronic obstructive pulmonary disease [translated into Chinese].

404nOtfound, 86, 2890–2892.

Source: NC State University Libraries
Added: August 6, 2018

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