Center for Human Health and the Environment

Works Published in 2016

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Displaying works 81 - 100 of 284 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 journal article

Webcams, Crowdsourcing, and Enhanced Crosswalks: Developing a Novel Method to Analyze Active Transportation

Frontiers in Public Health, 4.

By: J. Hipp n, A. Manteiga*, A. Burgess*, A. Stylianou* & R. Pless*

author keywords: crowdsourcing; active transportation; webcams; built environment; crosswalks; pedestrian detection; bicyclist detection
TL;DR: A novel method of active transportation research using webcams and crowdsourcing was developed and presented to determine if crosswalk enhancement was associated with changes in active transportation rates, including across a variety of weather conditions. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 28, 2019

2016 journal article

Does Availability of Worksite Supports for Physical Activity Differ by Industry and Occupation?

American Journal of Health Promotion, 32(3), 517–526.

author keywords: health promotion; occupation; physical activity; worksite
MeSH headings : Adult; Aged; Bicycling; Cross-Sectional Studies; Environment Design; Exercise; Female; Health Promotion / organization & administration; Humans; Industry / statistics & numerical data; Leisure Activities; Logistic Models; Male; Middle Aged; Occupational Health / statistics & numerical data; Occupations / statistics & numerical data; Transportation / statistics & numerical data; Walking; Workplace / organization & administration; Young Adult
TL;DR: Various combinations of WSS may increase the likelihood that employees will meet PA recommendations, including flexible time for exercise and maps of worksite-adjacent walk/bike routes. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref
Added: September 23, 2019

2016 journal article

Exploring associations between perceived home and work neighborhood environments, diet behaviors, and obesity: Results from a survey of employed adults in Missouri

Preventive Medicine Reports, 4, 591–596.

Contributors: R. Tabak*, J. Hipp n, E. Dodson*, L. Yang, D. Adlakha* & R. Brownson*

TL;DR: Investigating whether perceptions of built environment factors related to eating in the residential neighborhood will have different, independent associations with BMI and dietary behaviors than perceived built environment Factors in the worksite neighborhood found few associations after adjustment, and none were identified with the workplace neighborhood environment. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 23, 2019

2016 journal article

Urinary Concentrations of Phthalate Metabolites and Bisphenol A and Associations with Follicular-Phase Length, Luteal-Phase Length, Fecundability, and Early Pregnancy Loss

Environmental Health Perspectives, 124(3), 321–328.

By: A. Jukic*, A. Calafat*, D. McConnaughey*, M. Longnecker*, J. Hoppin n, C. Weinberg*, A. Wilcox*, D. Baird* ...

MeSH headings : Abortion, Spontaneous / chemically induced; Abortion, Spontaneous / urine; Adult; Benzhydryl Compounds / toxicity; Benzhydryl Compounds / urine; Environmental Pollutants / toxicity; Environmental Pollutants / urine; Female; Fertility / drug effects; Follicular Phase / drug effects; Humans; Luteal Phase / drug effects; Phenols / toxicity; Phenols / urine; Phthalic Acids / toxicity; Phthalic Acids / urine; Pregnancy; Pregnancy Trimester, First
TL;DR: Menstrual cycle–specific estimates of urinary BPA and phthalate metabolites were not associated with detrimental alterations in follicular-phase length, time to pregnancy, or early pregnancy loss, and in fact, DEHP [di(2-ethylhexyl)phthalate] metabolites and ΣDEHP were associated with reduced early loss. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 17, 2019

2016 journal article

High pesticide exposure events and DNA methylation among pesticide applicators in the agricultural health study

Environmental and Molecular Mutagenesis, 58(1), 19–29.

By: J. Rusiecki*, L. Beane Freeman*, M. Bonner*, M. Alexander*, L. Chen*, G. Andreotti*, K. Barry*, L. Moore* ...

author keywords: DNA methylation; pesticides; exposure; Agricultural Health Study; epigenetics
MeSH headings : Air Pollutants, Occupational / toxicity; Antigens, CD; Cadherins / genetics; DNA / blood; DNA Methylation / drug effects; DNA Methylation / genetics; DNA Modification Methylases / genetics; DNA Repair Enzymes / genetics; Farmers; Glutathione S-Transferase pi / genetics; Humans; Iowa; Male; North Carolina; Occupational Exposure / adverse effects; Occupational Exposure / analysis; Occupational Health; Pesticides / toxicity; Promoter Regions, Genetic; Prospective Studies; Surveys and Questionnaires; Tumor Suppressor Proteins / genetics
TL;DR: Evaluated association between experiencing unusually high pesticide exposure events (HPEEs) and DNAm among pesticide applicators in the Agricultural Health Study, a prospective study of applicators from Iowa and North Carolina found non‐specific HPEEs may contribute to increasedDNAm in GSTp1, and in some groups, reduced DNAm in MGMT and LINE‐1. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref
Added: September 13, 2019

2016 journal article

Greater Coronary Heart Disease Risk With Lower Intensity and Longer Duration Smoking Compared With Higher Intensity and Shorter Duration Smoking: Congruent Results Across Diverse Cohorts

Nicotine & Tobacco Research, 19(7), ntw290.

By: J. Lubin*, D. Albanes*, J. Hoppin n, H. Chen*, C. Lerro*, S. Weinstein*, D. Sandler*, L. Beane Freeman*

MeSH headings : Aged; Cohort Studies; Coronary Disease / epidemiology; Coronary Disease / mortality; Double-Blind Method; Finland / epidemiology; Humans; Male; Middle Aged; Risk Factors; Smoking / epidemiology; Smoking Cessation / methods; Time Factors; Tobacco Products / statistics & numerical data
TL;DR: In inverse smoking intensity effects in multiple cohorts with differing smoking patterns and other characteristics are observed, suggesting a common underlying phenomenon that offers clues to better understanding biological mechanisms and reinforces the importance of cessation rather than smoking less to reduce CHD risk. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: NC State University Libraries, Crossref
Added: September 13, 2019

2016 journal article

Genital morphology and allometry differ by species and sex in Malawi cichlid fishes

Hydrobiologia, 791(1), 127–143.

author keywords: Genital morphology; Cichlid fishes; Sexual dimorphism; Anogenital distance; Genital papilla
TL;DR: It is found that the most sexually distinct morphology is in the Lake Malawi rock cichlids and the least sexual dimorphism in the riverine outgroup; additionally, diversity in metrics within genus indicates that these traits are recently evolving. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: NC State University Libraries, Crossref
Added: September 11, 2019

2016 journal article

Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours

Proceedings of the Nutrition Society, 76(2), 130–144.

By: H. Patisaul n

author keywords: Soya; Isoflavones; Genistein; Equol; Endocrine disruption; Oestrogen; ER; ER; Brain; Hypothalamus
MeSH headings : Animals; Benzhydryl Compounds / adverse effects; Diet; Disease Models, Animal; Endocrine Disruptors / adverse effects; Humans; Isoflavones / adverse effects; Neurosecretory Systems / drug effects; Phenols / adverse effects; Phytoestrogens / adverse effects; Reproduction / drug effects; Sexual Behavior / drug effects; Sexual Behavior, Animal / drug effects; Soybeans / chemistry
TL;DR: As oestrogen receptor partial agonists with molecular and cellular properties similar to anthropogenic endocrine disruptors such as bisphenol A, the soya phyto-oestrogens provide an interesting model for how attitudes about what is ‘synthetic’ v. what is‘natural,’ shapes understanding and perception of what it means for a compound to be endocrine disrupting and/or potentially harmful. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 17, 2019

2016 journal article

Erratum: Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons

Nature Genetics, 48(6), 700–700.

By: I. Braasch, A. Gehrke, J. Smith, K. Kawasaki, T. Manousaki, J. Pasquier, A. Amores, T. Desvignes ...

TL;DR: The draft spotted gar genome sequence is made publicly available, the assembly LepOcu1 publicly available from NCBI since 13 January 2012 under accession code GCA000242695. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019

2016 journal article

Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish

The Journal of Experimental Medicine, 213(6), 979–992.

By: F. Moore*, E. Garcia*, R. Lobbardi*, E. Jain*, Q. Tang*, J. Moore*, M. Cortes*, A. Molodtsov* ...

MeSH headings : Amino Acid Substitution; Animals; DNA-Binding Proteins / genetics; DNA-Binding Proteins / immunology; Hematopoiesis / genetics; Hematopoiesis / immunology; Hematopoietic Stem Cells / immunology; Hematopoietic Stem Cells / pathology; Killer Cells, Natural / immunology; Killer Cells, Natural / pathology; Mutation, Missense; Neoplastic Stem Cells / immunology; Neoplastic Stem Cells / pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology; Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology; T-Lymphocytes / immunology; T-Lymphocytes / pathology; Transcription, Genetic / genetics; Transcription, Genetic / immunology; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR: The first single-cell gene expression analysis in zebrafish blood is reported to distinguish major blood lineages, identify new cell types, and delineate heterogeneity in T cell leukemia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019

2016 journal article

Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure

Data in Brief, 6, 989–997.

author keywords: Inhalation; Iron; Manganese; Monkey
TL;DR: Liver manganese and iron levels were linearly correlated although only the intermediate mangansese exposure level (0.3 mg Mn/m3) led to a statistically significant increase in liver iron levels. (via Semantic Scholar)
Source: Crossref
Added: July 21, 2019

2016 conference paper

Single DNA imaging and length quantification through a mobile phone microscope

Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 9699.

By: Q. Wei*, W. Luo*, S. Chiang*, T. Kappel*, C. Mejia*, D. Tseng*, R. Chan*, E. Yan* ...

Contributors: Q. Wei*, W. Luo*, S. Chiang*, T. Kappel*, C. Mejia*, D. Tseng*, R. Chan*, E. Yan* ...

author keywords: mobile phone microscopy; fluorescence; DNA imaging; point of care; mobile health; single-molecule imaging; telemedicine; mobile health
TL;DR: A mobile-phone integrated fluorescence microscopy platform that allows imaging and sizing of single DNA molecules that are stretched on a chip and can be very useful for various diagnostic applications including the detection of disease-specific genes and quantification of copy-number-variations at POC settings. (via Semantic Scholar)
Source: ORCID
Added: March 21, 2019

2016 journal article

Mobile Phone-Based Microscopy, Sensing, and Diagnostics

IEEE Journal on Selected Topics in Quantum Electronics, 22(3).

By: J. Contreras-Naranjo*, Q. Wei* & A. Ozcan*

Contributors: J. Contreras-Naranjo*, Q. Wei* & A. Ozcan*

author keywords: Diagnostics; mobile health; telemedicine; microscopy; sensing
TL;DR: Recent advances in the use of mobile phone-based imaging and sensing techniques for point of care applications, including microscopy and diagnostic testing are focused on. (via Semantic Scholar)
Source: ORCID
Added: March 21, 2019

2016 journal article

The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes.

http://europepmc.org/abstract/med/26801775

By: I. Rodriguez-Nunez, D. Wcisel, R. Litman, G. Litman, J. Yoder & Immunogenetics

Source: ORCID
Added: February 13, 2019

2016 journal article

Angiopellosis as an Alternative Mechanism of Cell Extravasation

STEM CELLS, 35(1), 170–180.

By: T. Allen n, D. Gracieux n, M. Talib n, D. Tokarz n, M. Hensley n, J. Cores n, A. Vandergriff n, J. Tang n ...

author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
TL;DR: In injected cardiac and mesenchymal stem cells, the vascular wall undergoes an extensive remodeling to allow the cell to exit the lumen, while the injected cell remains distinctively passive in activity. (via Semantic Scholar)
Sources: ORCID, NC State University Libraries, Crossref
Added: February 13, 2019

2016 journal article

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish

Protein Science, 25(11), 2076–2088.

By: M. Tucker n, S. MacKenzie n, J. Maciag n, H. Dirscherl Ackerman, P. Swartz n, J. Yoder n, P. Hamilton n, A. Clay Clark*

author keywords: phage display substrate library; substrate recognition; Danio rerio; apoptosis
MeSH headings : Allosteric Regulation; Animals; Caspase 3 / chemistry; Crystallography, X-Ray; Molecular Dynamics Simulation; Peptide Library; Substrate Specificity; Zebrafish
TL;DR: The structure of zebrafish Casp3a is determined to 2.28Å resolution by X‐ray crystallography, and the results suggest that a limited number of amino acid substitutions near the active site result in plasticity of the S4 sub‐site by increasing flexibility of one active site loop and by affecting hydrogen‐bonding with substrate. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 13, 2019

2016 journal article

Digital image quantification of siderophores on agar plates

Data in Brief, 6, 890–898.

By: M. Andrews n, C. Santelli* & O. Duckworth n

Contributors: M. Andrews n, C. Santelli* & O. Duckworth n

TL;DR: Visual image data and detailed methodology for the use of a new method for quantifying the exudation of siderophores during fungal growth are presented and protocols for making CAS assay layer plates are provided. (via Semantic Scholar)
Source: ORCID
Added: February 5, 2019

2016 journal article

Occurrence of Host-Associated Fecal Markers on Child Hands, Household Soil, and Drinking Water in Rural Bangladeshi Households

Environmental Science & Technology Letters, 3(11), 393–398.

TL;DR: Evidence of widespread ruminant and avian fecal contamination in the compound environment is found; non-human fecal marker occurrence scaled with animal ownership and strategies for controlling non- human fecal waste should be considered when designing interventions to reduce exposure to fecal contaminations in low-income settings. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: January 30, 2019

2016 journal article

Hand- and Object-Mouthing of Rural Bangladeshi Children 3-18 Months Old

International Journal of Environmental Research and Public Health, 13(6).

author keywords: non-dietary ingestion; child behavior; mouthing; exposure factors; rural; Bangladesh
MeSH headings : Bangladesh; Environmental Exposure / analysis; Environmental Exposure / statistics & numerical data; Environmental Pollutants; Ethnicity; Female; Hand; Humans; Infant; Male; Motor Activity; Mouth; Risk Assessment; United States
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 30, 2019

2016 journal article

Negative Control Outcomes: A Tool to Detect Bias in Randomized Trials

JAMA, 316(24), 2597–2598.

MeSH headings : Bias; Biomedical Research / methods; Biomedical Research / statistics & numerical data; Confounding Factors, Epidemiologic; Intention to Treat Analysis; Randomized Controlled Trials as Topic; Selection Bias
TL;DR: A formal approach has recently been suggested for its use to detect confounding, selection, and measurement bias in epidemiological studies. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 30, 2019

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