Works Published in 2011
Displaying works 121 - 140 of 608 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
Permeability control in stimulus-responsive colloidosomes
Soft Matter, 7(5), 1948–1956.
Contributors: A. Miguel * & S. Behrens *
TL;DR:
A novel class of aqueous core colloidosomes that combine the benefit of low capsule permeability (good cargo retention) with the option of a stimulus-triggered fast release in a target environment is presented.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2011 journal article
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering”
Correction to “Correlating Aggregation Kinetics and Stationary Diffusion in Protein–Sodium Salt Systems Observed with Dynamic Light Scattering.” The Journal of Physical Chemistry B, 115(36), 10778–10778.
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2011 journal article
An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells
Molecular Therapy, 19(4), 667–675.
MeSH headings : Animals; Cells, Cultured; Chromatography; Dependovirus / genetics; Female; Fluorescent Antibody Technique; Gene Transfer Techniques; Neural Stem Cells / virology; Polymerase Chain Reaction; Rats; Rats, Inbred F344
TL;DR:
This work applied directed evolution to create a "designer" AAV vector with enhanced delivery efficiency for neural stem cells (NSCs), and a novel AAV variant, carrying an insertion of a selected peptide sequence on the surface of the threefold spike within the heparin-binding site, emerged from this evolution.
(via Semantic Scholar)
doi.org (publisher)
Source: Crossref
Added: August 28, 2020
2011 journal article
Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells
STEM CELLS, 29(11), 1886–1897.
author keywords: Neural stem cells; Cellular mechanotransduction; Rho GTP-binding proteins; Adipose stem cells; Extracellular matrix; Elastic modulus
MeSH headings : Animals; Apoptosis / genetics; Apoptosis / physiology; Cell Differentiation / genetics; Cell Differentiation / physiology; Cell Proliferation; Cells, Cultured; Extracellular Matrix / metabolism; Female; Fluorescent Antibody Technique; Mechanotransduction, Cellular / genetics; Mechanotransduction, Cellular / physiology; Microscopy, Atomic Force; Neural Stem Cells / cytology; Neural Stem Cells / metabolism; Neurogenesis / genetics; Neurogenesis / physiology; Rats; Rats, Inbred F344; cdc42 GTP-Binding Protein / genetics; cdc42 GTP-Binding Protein / metabolism; rho GTP-Binding Proteins / genetics; rho GTP-Binding Proteins / metabolism; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism
TL;DR:
These results establish Rho GTPase‐based mechanotransduction and cellular stiffness as biophysical regulators of NSC fate in vitro and RhoA as an important regulatory protein in the hippocampal stem cell niche.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Additive effects of herbivory, nectar robbing and seed predation on male and female fitness estimates of the host plant Ipomopsis aggregata
Oecologia, 166(3), 681–692.
author keywords: Herbivory; Ipomopsis aggregata; Nectar robbing; Nectar; Phenology; Pollination; Pollen deposition; Seed predation; Trait-based approach
MeSH headings : Animals; Bees / physiology; Birds / physiology; Colorado; Deer / physiology; Diptera / physiology; Feeding Behavior; Food Chain; Genetic Fitness; Magnoliopsida / physiology; Plant Nectar / physiology; Pollination; Reproduction; Seeds / physiology; Sex Characteristics
TL;DR:
The results suggest that the effects of multiple antagonists on estimates of plant fitness can be additive, and investigating which traits respond to damage can provide insight into how antagonists shape plant performance.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Behavioral epigenetics: A new frontier in the study of hormones and behavior
Hormones and Behavior, 59(3), 277–278.
MeSH headings : Animals; Behavior, Animal / physiology; Epigenesis, Genetic; Epigenomics / methods; Hormones / genetics
TL;DR:
In this special issue of Hormones & Behavior, the diverse and innovative approaches to addressing this challenge of establishing the link between epigenetic effects, the experience of environmental variation, and the variety of phenotypic outcomes that emerge are highlighted.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
The role of Bisphenol A in shaping the brain, epigenome and behavior
Hormones and Behavior, 59(3), 296–305.
author keywords: Bisphenol A; Epigenetics; Social behavior; DNA methylation; Endocrine disrupting compound
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds; Brain / drug effects; Epigenesis, Genetic / drug effects; Estrogens, Non-Steroidal / pharmacology; Female; Humans; Learning / drug effects; Maternal Behavior / drug effects; Phenols / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects; Sex Characteristics
TL;DR:
An updated review of BPA's action on the brain and behavior is presented, discussing its role as both an endocrine active compound and an agent that alters DNA methylation.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
NTP-CERHR expert panel report on the developmental toxicity of soy infant formula
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 92(5), 421–468.
author keywords: endocrine disrupters; nutrition; safety assessment
MeSH headings : Animals; Female; Humans; Infant; Infant Formula / chemistry; Infant, Newborn; Isoflavones / adverse effects; Isoflavones / pharmacokinetics; Isoflavones / toxicity; Male; Mice; Phytoestrogens / adverse effects; Phytoestrogens / pharmacokinetics; Phytoestrogens / toxicity; Rats; Soy Foods / adverse effects; Soybean Proteins / chemistry; Soybean Proteins / pharmacology; Soybean Proteins / toxicity
TL;DR:
This updated evaluation of soy infant formula does not include an assessment on the potential reproductive toxicity of genistein following exposures during adulthood as was carried out in the 2006 evaluation, and focuses only on Soy infant formula and the potential developmental toxicity of its major isoflavone components.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10
Nature, 469(7331), 534–538.
MeSH headings : Alleles; Animals; Behavior, Animal / physiology; Central Nervous System / embryology; Female; GRB10 Adaptor Protein / genetics; GRB10 Adaptor Protein / metabolism; Gene Expression Regulation, Developmental; Genomic Imprinting / genetics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Social Dominance
TL;DR:
It is demonstrated that within the brain Grb10 is expressed from the paternal allele from fetal life into adulthood and that ablation of this expression engenders increased social dominance specifically among other aspects of social behaviour, a finding supported by the observed increase in allogrooming by paternal Grb 10-deficient animals.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2011 journal article
Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches
Chemical Research in Toxicology, 24(8), 1251–1262.
MeSH headings : Animals; Chemical and Drug Induced Liver Injury / metabolism; Chemical and Drug Induced Liver Injury / pathology; Databases, Factual; Hepatocyte Nuclear Factor 4 / metabolism; Male; Models, Statistical; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Small Molecule Libraries / chemistry; Small Molecule Libraries / toxicity; Toxicogenetics
TL;DR:
Results suggest that concurrent exploration of the chemical features and acute treatment-induced changes in transcript levels will both enrich the mechanistic understanding of subchronic liver injury and afford models capable of accurate prediction of hepatotoxicity from chemical structure and short-term assay results.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2
Nature Genetics, 43(6), 539–546.
MeSH headings : Adolescent; Adult; Child; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 20; Cystic Fibrosis / genetics; Female; Genetic Linkage; Genome-Wide Association Study; Humans; Lung Diseases / genetics; Male; Phenotype; Quantitative Trait Loci
TL;DR:
The authors' findings provide insight into the causes of variation in lung disease severity in cystic fibrosis and suggest new therapeutic targets for this life-limiting disorder.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
MicroRNA expression in the livers of inbred mice
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 714(1-2), 126–133.
author keywords: MicroRNA; Liver; Mouse; Gene expression
MeSH headings : Animals; Gene Expression; Liver / metabolism; Mice; Mice, Inbred Strains / genetics; MicroRNAs / metabolism; Polymorphism, Single Nucleotide
TL;DR:
The stability of mouse liver miRNA expression in a genetically diverse population suggests that treatment-induced disruptions in liver mi RNA expression may indicate an important mechanism for the disturbance of normal liver function, and may prove to be a useful genetic background-independent biomarker of toxicant effect.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies
Pediatric Pulmonology, 46(9), 857–869.
author keywords: forced expiratory volume; age effects; severity of illness index
MeSH headings : Adolescent; Child; Chronic Disease; Clinical Trials as Topic; Cystic Fibrosis / genetics; Cystic Fibrosis / mortality; Female; Humans; Male; Multicenter Studies as Topic; Phenotype; Respiratory Function Tests; Severity of Illness Index; Survival Analysis
TL;DR:
Genetic studies of lung disease in cystic fibrosis are hampered by the lack of a severity measure that accounts for chronic disease progression and mortality attrition and combining analyses across studies requires common phenotypes that are robust to study design and patient ascertainment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Large-Scale Asymmetric Synthesis of the Bioprotective Agent JP4-039 and Analogs
Organic Letters, 13(9), 2318–2321.
MeSH headings : Amines / chemistry; Esters / chemistry; Models, Molecular; Molecular Structure; Nitrogen Oxides / chemical synthesis; Stereoisomerism
TL;DR:
JP4-039 is a novel nitroxide conjugate capable of crossing lipid bilayer membranes and scavenging reactive oxygen species (ROS) and an efficient and scalable one-pot hydrozirconation-transmetalation-imine addition methodology has been developed for its asymmetric preparation.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2011 journal article
Rac/JNK/dub regulates intercellular adhesive dynamics during gut morphogenesis
Developmental Biology, 356(1), 141.
TL;DR:
It is shown that the activity of Jun N-terminal kinase (JNK) is required for Xenopus gut morphogenesis, and data suggest that a Rac/JNK/dub pathway orchestrates tissue-elongating endoderm cell rearrangements during gut Morphogenesis by regulating intercellular adhesive dynamics.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2011 journal article
Complex genetic architecture of Drosophila aggressive behavior
Proceedings of the National Academy of Sciences, 108(41), 17070–17075.
MeSH headings : Aggression / physiology; Animals; Behavior, Animal / physiology; Brain / anatomy & histology; Crosses, Genetic; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Evolution, Molecular; Female; Gene Expression; Gene Regulatory Networks; Genes, Insect; Male; Mutation; Phenotype
TL;DR:
The transcriptional signatures of homozygous and double heterozygous genotypes derived from the six mutations imply a large mutational target for aggressive behavior and point to evolutionarily conserved genetic mechanisms and neural signaling pathways affecting this universal fitness trait.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Crossref
Added: August 28, 2020
2011 journal article
Characterization and application of small RNAs and RNA silencing mechanisms in fungi
Fungal Biology Reviews, 25(4), 172–180.
TL;DR:
This review summarizes important classes of eukaryotic small RNAs and provides a current analysis of the RNA silencing machinery based on available fungal genome sequences and discusses opportunities for exploiting knowledge of smallRNAs andRNA silencing for practical application such as engineering plants resistant to fungal pathogens.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2011 journal article
New approach for the study of mite reproduction: The first transcriptome analysis of a mite, Phytoseiulus persimilis (Acari: Phytoseiidae)
Journal of Insect Physiology, 57(1), 52–61.
author keywords: Mite; Acari; Phytoseiidae; Transcriptome; 454; Vitellogenin; Vitellin; Yolk protein; Vitellogenin receptor; Yolk protein receptor; Tick; Female reproduction
MeSH headings : Animals; Female; Gene Expression Profiling / methods; Gene Expression Regulation; Male; Mites / classification; Mites / genetics; Mites / growth & development; Mites / physiology; Molecular Sequence Data; Phylogeny; Proteins / genetics; Proteins / metabolism
TL;DR:
The objective of this project was to obtain DNA-sequence information of expressed genes from P. persimilis with special interest in sequences corresponding to vitellogenin (Vg) and the viteLLogenin receptor (VGR) which are critical to the understanding ofvitellogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: August 28, 2020
2011 journal article
Diameter thresholds for distinguishing between red wolf and other canid scat
Wildlife Society Bulletin, 35(4), 416–420.
author keywords: Canis latrans; Canis rufus; coyote; DNA genotyping; hybrid; red wolf; scat
TL;DR:
These upper and lower thresholds of scat diameters are suggested to be used in concert with other methods to monitor for red wolf, coyote, and hybrid activity to help conserve a lone, free- ranging population of wild red wolves.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020
2011 journal article
Differential response in foliar chemistry of three ash species to emerald ash borer adult feeding
Journal of Chemical Ecology, 37(1), 29–39.
Contributors: Y. Chen*, J. Whitehill *, P. Bonello * & T. Poland *
author keywords: Agrilus planipennis; Fraxinus; Plant defense; Phenolics; Volatile organic compounds; VOCs; Coleoptera; Buprestidae
MeSH headings : Animals; Chromatography, High Pressure Liquid; Coleoptera / physiology; Feeding Behavior; Female; Fraxinus / chemistry; Fraxinus / parasitology; Plant Leaves / chemistry; Plant Leaves / parasitology; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Volatile Organic Compounds / analysis
TL;DR:
Although levels of total phenolics from black and green ash foliage were not affected by EAB adult feeding, they decreased significantly in white ash, and the possible ecological implications of these findings are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: August 24, 2020
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