Works Published in 2016
Displaying all 13 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Erratum: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases
Scientific Reports, 6(1), 19384.
TL;DR:
This work catalogueed age-related gene expression changes in nine tissues from nearly two hundred individuals collected by the Genotype-Tissue Expression (GTEx) project, finding the aging gene expression signatures are very tissue specific and enrichment for some well-known aging components such as mitochondrial biology is observed in many tissues.
(via Semantic Scholar)
www.nature.com (publisher PDF)
Source: Crossref
Added: January 4, 2021
2016 journal article
Integrative approaches for large-scale transcriptome-wide association studies
Nature Genetics, 48(3), 245–252.
MeSH headings : Animals; Gene Expression Regulation / genetics; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Mice; Obesity / genetics; Obesity / pathology; Phenotype; Quantitative Trait Loci / genetics; Transcriptome / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 24, 2020
2016 journal article
Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium
PloS One, 11(12), e0167503.
Source: ORCID
Added: October 7, 2019
2016 journal article
Genomic characterization of metformin hepatic response
PLoS Genetics, 12(11), e1006449.
Source: ORCID
Added: October 7, 2019
2016 journal article
Visualization of robust L1PCA
Stat, 5(1), 173–184.
author keywords: L1-norm; outlier; PCA; robustness
TL;DR:
The visual L1 principal component analysis (VL1PCA) is not only robust to outliers but also gives a meaningful population stratification for data even in the presence of special family structure, when other methods fail.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: October 7, 2019
2016 journal article
Estimation of interpretable eQTL effect sizes using a log of linear model
ArXiv Preprint ArXiv:1605.08799.
Source: ORCID
Added: October 7, 2019
2016 conference paper
Poster: risk-based attack surface approximation
Symposium and Bootcamp on the Science of Security, 121–123.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium
PLoS One, 11(12).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives
GREEN CHEMISTRY, 18(16), 4407–4419.
TL;DR:
An experimental and computational approach to categorizing UVCBs according to chemical and biological similarities is presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
The projack: a resampling approach to correct for ranking bias in high-throughput studies
Biostatistics (Oxford, England), 17(1), 54–64.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Integrative approaches for large-scale transcriptome-wide association studies
Nature Genetics, 48(3), 245–252.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Gene expression in major depressive disorder
Molecular Psychiatry, 21(3), 339–347.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Pathway Analysis for RNA-Seq Data Using a Score-Based Approach
BIOMETRICS, 72(1), 165–174.
author keywords: Linear model; Pathway analysis; RNA-seq; Statistical genetics
MeSH headings : Algorithms; Animals; Data Interpretation, Statistical; Data Mining / methods; Databases, Nucleic Acid; Female; High-Throughput Nucleotide Sequencing / methods; Male; Protein Interaction Mapping / methods; Rats; Sequence Analysis, RNA / methods; Sex Factors; Signal Transduction / genetics; Species Specificity; Transcription Factors / genetics
TL;DR:
Transitions to RNA‐Seq data are described to improve power for linear associations with outcome and flexibly handle normalization factors and it is demonstrated that the approach provides appropriate type I error control without actual permutation and is powerful under many settings in comparison to competing approaches.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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