Jennifer Holmes

Works (6)

Updated: October 29th, 2024 05:04

2024 journal article

Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 327(4), G513–G530.

By: J. Gookin n , J. Holmes n, L. Clarke *, S. Stauffer n, B. Meredith n, M. Vandewege n, N. Torres-Machado n, S. Friedenberg* ...

author keywords: comparative; electrogenic ion transport; epithelium; immunofluorescence; mucus
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2024

2024 journal article

Immunization of turkeys with <i>Clostridium septicum</i> alpha toxin-based recombinant subunit proteins can confer protection against experimental Clostridial dermatitis

PLOS ONE, 19(4).

By: F. John n, V. Criollo n, C. Gaghan n, A. Armwood n , J. Holmes n, A. Thachil*, R. Crespo n , R. Kulkarni  n

Ed(s): Y. Chang

UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 1, 2024

2024 journal article

Myeloid cell MHC I expression drives CD8<SUP>+</SUP> T cell activation in nonalcoholic steatohepatitis

FRONTIERS IN IMMUNOLOGY, 14.

By: V. Adams n, L. Collins n , T. Williams n , J. Holmes n, P. Hess n , H. Atkins n, G. Scheidemantle n, X. Liu n ...

Contributors: T. Williams n , V. Adams n, L. Collins n , J. Holmes n, P. Hess n , H. Atkins n, G. Scheidemantle n, X. Liu n ...

Ed(s): T. Williams n , L. Collins n  & A. Kennedy n 

author keywords: liver; NASH; fibrosis; H2Kb; CD8(+) T cells; immunopeptidome
TL;DR: Activated hepatic CD8+ T cells are dependent on myeloid cell MHC class I expression in diet induced NASH to promote inflammation and fibrosis and a role of NADPH oxidase in the production of Ncf2 peptide generation is suggested. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2024

2022 journal article

Long‐term effects of ciclosporin and oclacitinib on mediators of tolerance, regulatory T‐cells, <scp>IL</scp>‐10 and <scp>TGF</scp>‐β, in dogs with atopic dermatitis

Veterinary Dermatology, 34(2), 107–114.

By: I. Herrmann n , L. Mamo n, J. Holmes n, J. Mohammed n, K. Murphy  n & P. Bizikova n

author keywords: canine atopic dermatitis; ciclosporin; oclacitinib; T regulatory cell
MeSH headings : Dogs; Animals; Cyclosporine / therapeutic use; T-Lymphocytes, Regulatory; Interleukin-10; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / veterinary; Transforming Growth Factor beta1 / therapeutic use; Transforming Growth Factor beta / therapeutic use; Immune Tolerance; Dog Diseases / drug therapy
TL;DR: Lower Treg cell percentages in the CSA-treated dogs suggest an impact of this drug on this cell population; however, it does not necessarily mean that it diminishes tolerance. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 3, 2023

2021 journal article

Dog leukocyte antigen-88*034:01 presents nonamer peptides from canine distemper virus hemagglutinin, large polymerase, and matrix proteins

HLA, 97(5), 428–434.

By: P. Nemec n, J. Holmes n & P. Hess n 

author keywords: distemper virus; canine; dogs; epitopes; major histocompatibility complex; peptides; T-lymphocytes; cytotoxic
MeSH headings : Alleles; Animals; Distemper Virus, Canine / genetics; Dogs; Hemagglutinins; Leukocytes; Peptides
TL;DR: The allomorph's binding motif is experimentally confirmed by developing an MHC surface stabilization assay, which adds new tools for studying neoepitope‐specific CTL in Boxers to foster canine comparative oncology. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 4, 2021

2021 article

High-resolution characterization of the structural features and genetic variation of six feline leukocyte antigen class I loci via single molecule, real-time (SMRT) sequencing

Holmes, J. C., Scholl, E. H., Dickey, A. N., & Hess, P. R. (2021, June 27). IMMUNOGENETICS, Vol. 6.

By: J. Holmes n, E. Scholl n, A. Dickey n & P. Hess n 

author keywords: Cats; Class I genes; High-throughput DNA sequencing; Major histocompatibility complex; Polymorphism
MeSH headings : Animals; Cats; Exons; Genes, MHC Class I / genetics; Genetic Variation; Haplotypes; High-Throughput Nucleotide Sequencing; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Sequence Analysis, DNA / methods
TL;DR: A targeted approach to FLAI genotyping, using the single-molecule real-time (SMRT) platform, which allows full-length (3.4-kb) reads without assembly, is developed, which could allow highly accurate allele surveys in large cat cohorts. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 6, 2021

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.