Works Published in 2017
Displaying works 21 - 40 of 248 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Genetic effects on gene expression across human tissues
Nature, 550(7675), 204–213.
Ed(s): A. Battle *, C. Brown *, B. Engelhardt * & S. Montgomery *
MeSH headings : Alleles; Chromosomes, Human / genetics; Disease / genetics; Female; Gene Expression Profiling; Gene Expression Regulation / genetics; Genetic Variation; Genome, Human / genetics; Genotype; Humans; Male; Organ Specificity / genetics; Quantitative Trait Loci / genetics
TL;DR:
It is found that local genetic variation affects gene expression levels for the majority of genes, and inter-chromosomal genetic effects for 93 genes and 112 loci are identified, enabling a mechanistic interpretation of gene regulation and the genetic basis of disease.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 27, 2021
2017 content posted
Cadmium Disrupts Vestibular Function by Interfering with Otolith Formation
TL;DR:
It is demonstrated that the addition of calcium rescues otolith malformation and reduces circling behavior but has no ameliorating effect on hyperactivity, suggesting that hyperactivity and balance disorders in human populations exposed to Cd are manifestations of separate underlying molecular pathways.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 17, 2021
2017 journal article
Gestational high-fat diet and bisphenol A exposure heightens mammary cancer risk
Endocrine-Related Cancer, 24(7), 365–378.
Contributors: Y. Leung*, V. Govindarajah *, A. Cheong*, J. Veevers*, D. Song *, R. Gear*, X. Zhu *, J. Ying *
author keywords: breast cancer; developmental origin of health and disease (DOHaD); RNA-seq; transcriptomics; DNA methylation; patient survival; TCGA; windows of susceptibility; in utero exposure; bisphenol A; high-butter fat diet; non-monotonic response
MeSH headings : Animals; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Diet, High-Fat; Female; Mammary Glands, Animal / drug effects; Mammary Neoplasms, Experimental / chemically induced; Mammary Neoplasms, Experimental / etiology; Mammary Neoplasms, Experimental / pathology; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Risk
TL;DR:
Concurrent HBF dietary and a low-dose BPA exposure during pregnancy increases mammary tumor incidence in offspring, accompanied by alterations in mammary gland development and gene expression, and possibly through epigenetic reprogramming.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 5, 2021
2017 book
Endocrine Disruptors, Brain, and Behavior
In Oxford Scholarship Online.
Source: ORCID
Added: March 5, 2021
2017 journal article
Using QIIME to Interpret Environmental Microbial Communities in an Upper Level Metagenomics Course
CourseSource, 4.
TL;DR:
Students first familiarize themselves with the format of QIIME commands with a worksheet that deconstructs a command to help students understand the input, output, and arguments, and build student confidence in their ability to analyze high-throughput sequencing results of metagenomic datasets with the open-source QIime pipeline.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2017 journal article
What is Recklessness in Scientific Research? The Frank Sauer Case
Accountability in Research, 24(8), 497–502.
author keywords: Collaboration; data management; misconduct in research; research ethics; research integrity; science policy
MeSH headings : Ethics, Research; Research Support as Topic / ethics; Research Support as Topic / legislation & jurisprudence; Scientific Misconduct / legislation & jurisprudence; United States; United States Office of Research Integrity / legislation & jurisprudence
TL;DR:
The case raises some interesting and important questions concerning research integrity because it focused on the legal issue of what constitutes recklessness in scientific research.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2017 journal article
Unique Down to Our Microbes—Assessment of an Inquiry-Based Metagenomics Activity †
Journal of Microbiology & Biology Education, 18(2).
TL;DR:
An inquiry-based activity designed for introductory life science majors and nonmajors, students perform an investigation of the bacterial communities inhabiting the human belly button and associated metagenomics data collected through a citizen science project and visualized using an open-access bioinformatics tool.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2017 article
Barriers to Integration of Bioinformatics into Undergraduate Life Sciences Education
Williams, J., Drew, J., Galindo-Gonzalez, S., Robic, S., Dinsdale, E., Morgan, W., … Pauley, M. (2017, October 19). (Vol. 10). Vol. 10.
TL;DR:
An extensive survey of life sciences faculty in the United States found that the cohort of faculty with the most recently awarded PhD degrees reported the most training but were teaching bioinformatics at a lower rate than faculty who earned their degrees in previous decades.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2020
2017 journal article
Metabolomic profiles of arsenic (+3 oxidation state) methyltransferase knockout mice: effect of sex and arsenic exposure
Archives of Toxicology, 91(1), 189–202.
author keywords: Arsenic; Metabolomics; As3mt knockout; Mice; Urine; Plasma
MeSH headings : Amino Acids / metabolism; Animals; Arsenic / blood; Arsenic / metabolism; Arsenic / toxicity; Arsenic / urine; Arsenic Poisoning / blood; Arsenic Poisoning / enzymology; Arsenic Poisoning / metabolism; Arsenic Poisoning / urine; Arsenicals / blood; Arsenicals / metabolism; Arsenicals / urine; Biomarkers / blood; Biomarkers / urine; Biotransformation; Carbohydrate Metabolism / drug effects; Drug Resistance; Energy Metabolism / drug effects; Female; Lipid Metabolism / drug effects; Male; Metabolome / drug effects; Methylation; Methyltransferases / genetics; Methyltransferases / metabolism; Mice, Inbred C57BL; Mice, Knockout; Sex Characteristics; Toxicokinetics; Water Pollutants, Chemical / blood; Water Pollutants, Chemical / metabolism; Water Pollutants, Chemical / toxicity; Water Pollutants, Chemical / urine
TL;DR:
It is suggested that As3mt KO alters major metabolic pathways in a sex-specific manner, independent of iAs treatment, and that As 3mt may be involved in other cellular processes beyond iAs methylation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Crossref
Added: December 21, 2020
2017 journal article
MP92-09 Implications of Regionalizing Care in the Developing World: Impact of Distance to Referral Center on Compliance to Biopsy Recommendations in a Brazilian Prostate Cancer Screening Cohort
Journal of Urology, 197(4S).
TL;DR:
GI and urine complications represent the majority of drivers resulting in 30 day readmission and measures to specifically reduce these by appropriate patient education and close postdischarge surveillance may represent a high impact opportunity for quality improvement efforts after RP.
(via Semantic Scholar)
Source: Crossref
Added: December 7, 2020
2017 report
Resilience of diversity-disease risk interactions following wildfire disturbance
In Proceedings of the Sudden Oak Death Sixth Science Symposium [Tech. Rep. GTR-PSW-255.]. https://www.fs.usda.gov/treesearch/pubs/53990
Source: NC State University Libraries
Added: December 4, 2020
2017 journal article
Occupancy and abundance of Eleutherodactylus wightmanae and E. brittoni along elevational gradients in west-central Puerto Rico
Caribbean Naturalist, 40, 1–18.
Source: NC State University Libraries
Added: December 4, 2020
2017 journal article
Human identification and global patterns of craniofacial variation
La Revue De Médecine Légale, 8(4), 180.
UN Sustainable Development Goal Categories
10. Reduced Inequalities
(OpenAlex)
Source: Crossref
Added: November 21, 2020
2017 journal article
Interviewing neuroscientists for an undergraduate honors project
Journal of Undergraduate Neuroscience Education, 16(1), A89–A94.
Source: NC State University Libraries
Added: November 7, 2020
2017 weblog post
The value of science is reflected in your everyday decisions
Le Blanc, G. A. (2017, March 31). https://news.ncsu.edu/2017/03/the-value-of-science-leblanc-2017/
Source: NC State University Libraries
Added: October 30, 2020
2017 journal article
Transcriptomic analysis links gene expression to unilateral pollen-pistil reproductive barriers.
BMC Plant Biology, 4.
author keywords: Interspecific reproductive barriers; Interpopulation interactions; Plant mating system; Pollen-pistil transcriptomes; Self-incompatibility; Solanum habrochaites; Unilateral incompatibility; Wild tomato species
MeSH headings : Flowers / genetics; Flowers / physiology; Gene Expression; Gene Expression Profiling; Genes, Plant; Pollen / genetics; Pollen / physiology; Solanum / genetics; Solanum / physiology
TL;DR:
Gene expression analysis of reproductive tissues allowed us to better understand the molecular basis of interpopulation incompatibility at the level of pollen-pistil interactions and highlighted specific genes, including those in ROS signaling pathways that warrant further study in investigations of UI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 15, 2020
2017 journal article
Topological features of a gene co-expression network predict patterns of natural diversity in environmental response
Proceedings of the Royal Society B: Biological Sciences, 284(1856), 20170914.
author keywords: gene by environment interaction; gene regulatory network; Arabidopsis thaliana; abiotic stress; drought; cold
MeSH headings : Adaptation, Physiological / genetics; Arabidopsis / genetics; Arabidopsis / physiology; Cold Temperature; Droughts; Gene Expression Regulation, Plant; Gene Regulatory Networks
TL;DR:
This work investigated the network topology of genes putatively involved in local adaptation to two abiotic stressors—drought and cold—in Arabidopsis thaliana and suggested that the gene-interaction topologies for both cold and drought stress response are non-random.
(via Semantic Scholar)
Source: ORCID
Added: September 15, 2020
2017 journal article
Speciation as a Sieve for Ancestral Polymorphism
Molecular Ecology, 8.
author keywords: allopatric speciation; balancing selection; differential gene flow; genomic divergence
MeSH headings : Alleles; Gene Flow; Gene Frequency; Genetic Speciation; Genetics, Population; Genomics; Models, Genetic; Polymorphism, Genetic
TL;DR:
How ancestral balanced polymorphisms can be “sieved” by the speciation process, which sorts them unequally across descendant lineages is discussed.
(via Semantic Scholar)
Source: ORCID
Added: September 15, 2020
2017 journal article
Pervasive antagonistic interactions among hybrid incompatibility loci
PLOS Genetics, 13(6), e1006817.
Ed(s): C. Köhler
MeSH headings : Chromosome Mapping; Chromosomes, Plant / genetics; Epistasis, Genetic; Fertility / genetics; Genotype; Hybridization, Genetic; Solanum lycopersicum / genetics; Solanum lycopersicum / growth & development; Models, Genetic; Phenotype; Plant Infertility / genetics; Pollen / genetics; Quantitative Trait Loci / genetics; Reproductive Isolation; Seeds / genetics; Species Specificity
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: September 15, 2020
2017 journal article
Occupancy and Abundance of Eleutherodactylus Frogs in Coffee Plantations in Puerto Rico
Herpetologica, 73(4), 297.
author keywords: Acoustic surveys; Caribbean; Colonization rates; Habitat selection; Land use change
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 15, 2020
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