Works Published in 2013

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Displaying works 1 - 20 of 230 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 journal article

Methods for Facilitating Microbial Growth on Pulp Mill Waste Streams and Characterization of the Biodegradation Potential of Cultured Microbes

Journal of Visualized Experiments, 12(82).

By: S. Mathews n, A. Ayoub n, J. Pawlak n & A. Grunden n

TL;DR: Methods for the collection and modification of black liquor for microbial growth are aimed at utilization of this pulp waste to convert the lignin, organic acids, and polysaccharide degradation byproducts into valuable chemicals. (via Semantic Scholar)
Source: ORCID
Added: April 8, 2024

2013 journal article

A Genomic Survey of Reb Homologs Suggests Widespread Occurrence of R-Bodies in Proteobacteria

G3 Genes|Genomes|Genetics, 3(3), 505–516.

UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: April 4, 2024

2013 journal article

Manipulating or Superseding Host Recombination Functions: A Dilemma That Shapes Phage Evolvability

PLoS Genetics, 9(9), e1003825.

Ed(s): J. Casadesús

UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: April 4, 2024

2013 journal article

Multiplexed temporal coding of electric communication signals in mormyrid fishes

Journal of Experimental Biology, 216(13), 2365–2379.

TL;DR: The mormyrid electric communication pathway is a powerful model for integrating mechanistic studies of temporal coding with evolutionary studies of correlated differences in brain and behavior to investigate neural mechanisms for processing temporal codes. (via Semantic Scholar)
Source: ORCID
Added: November 14, 2023

2013 chapter

NEDD9

In J. L. Marshall (Ed.), Cancer Therapeutic Targets.

Ed(s): J. Marshall

Sources: Crossref, NC State University Libraries
Added: March 1, 2023

2013 journal article

Cilia and cilia-associated proteins in cancer

Drug Discovery Today: Disease Mechanisms, 10(3-4), e135–e142.

By: T. Seeger-Nukpezah*, J. Little*, V. Serzhanova* & E. Golemis*

TL;DR: Mechanisms by which changes in cilia can contribute to the formation and growth of tumors are discussed, and the cancer-relevance of cilia-dependent signaling pathways and proteins including mTOR, VHL, TSC, WNT, Aurora-A, NEDD9, and Hedgehog are emphasized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 1, 2023

2013 journal article

DNA Damage-Specific Control of Cell Death by Cryptochrome in p53-Mutant Ras-Transformed Cells

Cancer Research.

Contributors: J. Lee*, S. Gaddameedhi*, N. Ozturk*, R. Ye & A. Sancar*

MeSH headings : Animals; Cell Death / genetics; Cell Line; Cell Transformation, Neoplastic / genetics; Circadian Rhythm / genetics; Cryptochromes / genetics; Cryptochromes / physiology; DNA Damage; DNA-Binding Proteins / genetics; Doxorubicin / toxicity; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagens / toxicity; Mutation; Nuclear Proteins / genetics; Organoplatinum Compounds / toxicity; Oxaliplatin; Tumor Protein p73; Tumor Suppressor Proteins / genetics; Ultraviolet Rays / adverse effects
TL;DR: These findings establish distinct roles for cryptochromes in intrinsic apoptosis induced by UV mimetic and radiomimetic agents and Ras-transformed p53- and Cry-null mouse skin fibroblasts are more sensitive than p53 mutants to apoptotic cell death initiated by agents that activate either the intrinsic or the extrinsic apoptosis pathways. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 14, 2022

2013 journal article

Transposable elements re-wire and fine-tune the transcriptome.

9(1), 1003234.

MeSH headings : DNA Transposable Elements / genetics; Evolution, Molecular; Gene Expression Regulation; Genetic Variation; Humans; RNA, Messenger / genetics; Transcription, Genetic; Transcriptome / genetics
TL;DR: How TEs—particularly retrotransposons—contribute to transcript diversity and consider their potential significance as a source of small RNAs that regulate host gene transcription are explored. (via Semantic Scholar)
Source: ORCID
Added: September 28, 2022

2013 report

A Set of Scientific Issues Being Considered by the Environmental Protection Agency Regarding: Proposed Endocrine Disruptor Screening Program (EDSP) Tier 2 Ecotoxicity Tests

(SAP Minutes No. 2013-04). Environmental Protection Agency.

By: S. Kullman

Source: NC State University Libraries
Added: September 16, 2022

2013 journal article

Beliefs of science educators who teach pesticide risk to farmworkers

International Journal of Environmental and Science Education, 8(4), 587–609.

By: C. LePrevost, M. Blanchard & W. Cope

Source: NC State University Libraries
Added: September 16, 2022

2013 journal article

Short-Term Effects of Small Dam Removal on a Freshwater Mussel Assemblage

Freshwater Mollusk Biology and Conservation, 16(1), 41–52.

By: R. Heise*, W. Cope n, T. Kwak* & C. Eads n

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 15, 2022

2013 speech

Biofilms and Bioremediation

Presented at the BIT 100: Topics in Biotechnology, North Carolina State University, Raleigh, NC.

By: C. Goller

Event: BIT 100: Topics in Biotechnology, North Carolina State University at Raleigh, NC on September 4, 2013

Source: NC State University Libraries
Added: June 3, 2022

2013 speech

What/how do scientists and engineers write to learn?

Presented at the Campus Writing & Speaking Program’s Brown Bag Lunch, North Carolina State University, Raleigh NC.

By: C. Goller

Event: Campus Writing & Speaking Program’s Brown Bag Lunch, North Carolina State University at Raleigh NC on November 18, 2013

Source: NC State University Libraries
Added: June 3, 2022

2013 conference paper

Uncovering the biodiversity in Lake Raleigh utilizing bioinformatics and deep sequencing

Poster presented at the State of North Carolina Undergraduate Research and Creativity Symposium, Charlotte, NC.

By: M. Zinter & C. Goller

Event: State of North Carolina Undergraduate Research and Creativity Symposium at Charlotte, NC on November 16, 2013

Source: NC State University Libraries
Added: June 3, 2022

2013 speech

What I write

Goller, C. C. (2013, September). Presented at the ENG 101, Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University, Raleigh, NC.

By: C. Goller

Event: ENG 101, Featuring Scientists and Engineers in the Writing Class Program, North Carolina State University at Raleigh, NC on September 25, 2013

Source: NC State University Libraries
Added: June 3, 2022

2013 journal article

MazF6 toxin of Mycobacterium tuberculosis demonstrates antitoxin specificity and is coupled to regulation of cell growth by a Soj-like protein

BMC Microbiology, 13(1).

By: M. Ramirez*, C. Dawson*, R. Crew*, K. England* & R. Slayden*

author keywords: Mycobacterium tuberculosis; Cell cycle; MazF; Toxin:antitoxin; Soj(Mtb)
MeSH headings : Amino Acid Sequence; Animals; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Cell Cycle; Female; Gene Expression Regulation, Bacterial; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Molecular Sequence Data; Mycobacterium tuberculosis / genetics; Mycobacterium tuberculosis / growth & development; Mycobacterium tuberculosis / ultrastructure; Sequence Alignment
TL;DR: The first evidence of a coupled regulatory system in which cell cycle regulation via SojMtb is linked to downstream adaptations that are facilitated through the activity of the MazEF6 TA pair is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 30, 2022

2013 journal article

O-mannosylation of the Mycobacterium tuberculosis Adhesin Apa Is Crucial for T Cell Antigenicity during Infection but Is Expendable for Protection

PLoS Pathogens, 9(10), e1003705.

By: S. Nandakumar*, S. Kannanganat*, K. Dobos*, M. Lucas*, J. Spencer*, S. Fang*, M. McDonald*, J. Pohl* ...

Contributors: M. Ramirez*

Ed(s): P. Salgame

MeSH headings : Adhesins, Bacterial / genetics; Adhesins, Bacterial / immunology; Adhesins, Bacterial / metabolism; Animals; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Antigens, Bacterial / metabolism; Female; Glycosylation; Humans; Male; Mannose / genetics; Mannose / immunology; Mice; Mice, Inbred BALB C; Mycobacterium bovis / genetics; Mycobacterium bovis / immunology; Mycobacterium tuberculosis / genetics; Mycobacterium tuberculosis / immunology; Mycobacterium tuberculosis / metabolism; T-Lymphocytes / immunology; T-Lymphocytes / metabolism; Tuberculosis / genetics; Tuberculosis / immunology; Tuberculosis / metabolism; Tuberculosis / prevention & control; Tuberculosis Vaccines / genetics; Tuberculosis Vaccines / immunology
TL;DR: O-mannosylation of Apa is required for antigenicity but appears to be dispensable for its immunogenicity and protective efficacy in mice, which has implications for the development of subunit vaccines using post-translationally modified proteins such as glycoproteins against infectious diseases like tuberculosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 30, 2022

2013 journal article

Updating and curating metabolic pathways of TB

Tuberculosis, 93(1), 47–59.

By: R. Slayden*, M. Jackson*, J. Zucker*, M. Ramirez*, C. Dawson*, R. Crew*, N. Sampson*, S. Thomas* ...

author keywords: Metabolic pathways; Cell envelope; Outer membrane proteins; Cholesterol; Cell division; Regulation; Toxin antitoxin; Reannotation; Curate; Bioinformatics; Mycobacterium tuberculosis
MeSH headings : Bacterial Outer Membrane Proteins / physiology; Computational Biology / methods; Genes, Bacterial; Humans; Metabolic Networks and Pathways / genetics; Mycobacterium tuberculosis / genetics; Mycobacterium tuberculosis / metabolism; Open Reading Frames / genetics; Tuberculosis / metabolism
TL;DR: The Tuberculosis Community Annotation Project (TBCAP) jamboree exercise began the reannotation effort by providing additional information for previous annotations, and refining and substantiating the functional assignment of ORFs and genes within metabolic pathways. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 30, 2022

2013 journal article

Nucleotide excision repair in human cells: fate of the excised oligonucleotide carrying DNA damage in vivo.

The Journal of Biological Chemistry.

Contributors: J. Hu*, J. Choi*, S. Gaddameedhi*, M. Kemp*, J. Reardon* & A. Sancar*

MeSH headings : Animals; Cell Line; DNA Damage; DNA Repair / radiation effects; DNA-Binding Proteins / metabolism; Humans; Models, Biological; Mutation / genetics; Oligonucleotides / metabolism; Pyrimidine Dimers / metabolism; Transcription Factor TFIIH / metabolism; Transcription, Genetic / radiation effects; Ultraviolet Rays
TL;DR: It is demonstrated that dual incisions occur in vivo identical to the in vitro reaction, and the congruence of in vivo and in vitro data on nucleotide excision repair in humans is shown. (via Semantic Scholar)
Source: ORCID
Added: December 24, 2021

2013 journal article

Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells.

Nucleic Acids Research.

Shobhan Gaddameedhi

MeSH headings : Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; Humans; Kinetics; Luminescent Measurements / methods; Oligonucleotides; Pyrimidine Dimers / analysis; Ultraviolet Rays
TL;DR: The novel approach is robust, with essentially no signal in the absence of UV or a functional excision repair system, and allows for the sensitive detection of excision products within minutes following UV irradiation and does not require additional enrichment steps such as immunoprecipitation. (via Semantic Scholar)
Source: ORCID
Added: December 24, 2021

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