Works Published in 2006
Displaying works 1 - 20 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2006 journal article
Fatty acid synthase: a novel target for antiglioma therapy
British Journal of Cancer, 95(7), 869–878.
MeSH headings : Animals; Apoptosis / drug effects; Apoptosis / physiology; Astrocytes / drug effects; Base Sequence; Blotting, Western; Brain / enzymology; Brain Neoplasms / drug therapy; Brain Neoplasms / enzymology; Cell Line, Tumor; Cerulenin / pharmacology; Collagen Type XI / drug effects; Collagen Type XI / metabolism; Dose-Response Relationship, Drug; Enzyme Inhibitors / pharmacology; Fatty Acid Synthases / drug effects; Fatty Acid Synthases / genetics; Fatty Acid Synthases / metabolism; Flow Cytometry; Glioma / drug therapy; Glioma / enzymology; Humans; Molecular Sequence Data; Proto-Oncogene Proteins c-bcl-2 / metabolism; RNA, Small Interfering; Radiation Tolerance / drug effects; Rats; Transfection
TL;DR:
It is suggested that FAS might be a novel target for antiglioma therapy after it was found that RNAi-mediated knockdown of FAS leading to reduced FAS enzymatic activity was associated with decreased glioma cell viability.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 2, 2023
2006 journal article
Up-regulation of glucose regulated protein of M-r-78KDa (GRP78) followed by cisplatin treatment leads to mitochondrial mediated apoptosis through caspase-2 activation
Cancer Research. https://publons.com/wos-op/publon/54906422/
Contributors: S. Gaddameedhi , M. Ahmad & S. Chatterjee
Source: ORCID
Added: November 14, 2022
2006 report
Enhancing your waterfront property and aquatic resources
Raleigh, NC: North Carolina State University Press.
Source: NC State University Libraries
Added: September 23, 2022
2006 book
Standard guide for conducting laboratory toxicity tests with freshwater mussels
(Special Technical Report No. ASTM E2455-05). Conshohocken, PA: American Society for Testing and materials (ASTM).
Source: NC State University Libraries
Added: September 23, 2022
2006 journal article
Clam gape sensing equipment for water monitoring
Sea Technology, 3, 28–32.
Source: NC State University Libraries
Added: September 21, 2022
2006 chapter
Biomarker Responses of Unionid Mussels to Environmental Contaminants
In Freshwater Bivalve Ecotoxicology (pp. 257–284).
Sources: Crossref, NC State University Libraries
Added: September 15, 2022
2006 chapter
Toxicokinetics of Environmental Contaminants in Freshwater Bivalves
In Freshwater Bivalve Ecotoxicology (pp. 169–213).
Sources: Crossref, NC State University Libraries
Added: September 15, 2022
2006 journal article
Dynamic Gene Expression Changes Precede Dioxin-Induced Liver Pathogenesis in Medaka Fish
Toxicological Sciences, 89(2), 524–534.
author keywords: medaka; dioxin; liver; aryl hydrocarbon receptor; gene expression; transcription
MeSH headings : Animals; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A2 / genetics; Dose-Response Relationship, Drug; Gene Expression / drug effects; Gene Expression Profiling; Injections, Intraperitoneal; Liver / drug effects; Liver / metabolism; Liver / pathology; Male; Oligonucleotide Array Sequence Analysis; Oryzias; Polychlorinated Dibenzodioxins / toxicity; Receptors, Aryl Hydrocarbon / genetics; Reverse Transcriptase Polymerase Chain Reaction; Time Factors
TL;DR:
The data suggest that the cellular response to dioxin involves both AHRE- and non-AHRE-mediated transcription, and that coupling gene expression profiling with analysis of morphologic pathogenesis is essential for establishing temporal relationships between transcriptional changes, toxicity, and adaptation to hepatic injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 15, 2022
2006 journal article
A unified mixed-model method for association mapping that accounts for multiple levels of relatedness
Nature Genetics, 38(2), 203–208.
MeSH headings : Gene Expression; Genetic Techniques; Genetic Variation; Heredity / genetics; Humans; Models, Genetic; Phenotype; Quantitative Trait, Heritable; Research Design; Zea mays / genetics
TL;DR:
A unified mixed-model approach to account for multiple levels of relatedness simultaneously as detected by random genetic markers is developed and provides a powerful complement to currently available methods for association mapping.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Crossref, ORCID
Added: January 25, 2021
2006 journal article
Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: Implications for modulation of multiple homeostatic systems including feeding and sleep–wake behaviors
Neuroscience, 137(4), 1331–1346.
Contributors: S. Belcher* , A. Zsarnovszky*, P. Crawford*, H. Hemani*, L. Spurling* & T. Kirley *
author keywords: nucleoside triphosphate diphosphohydrolase; NTPDase3; CD39L3; immunohistochemistry; purinergic signaling; orexin/hypocretin co-localization
MeSH headings : Adenosine Triphosphate / metabolism; Amino Acid Sequence; Animals; Brain / enzymology; Brain / physiology; Cloning, Molecular; Feeding Behavior / physiology; Female; Homeostasis; Molecular Sequence Data; Nerve Fibers / enzymology; Ovariectomy; Peptide Fragments / chemistry; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase / metabolism; Pyrophosphatases / genetics; Pyrophosphatases / metabolism; Rats; Sleep / physiology; Wakefulness / physiology
Sources: Crossref, ORCID, NC State University Libraries
Added: January 21, 2021
2006 journal article
shRNA Silencing of AS3MT Expression Minimizes Arsenic Methylation Capacity of HepG2 Cells
Chemical Research in Toxicology, 19(7), 894–898.
MeSH headings : Arsenic / metabolism; Arsenic / toxicity; Base Sequence; Cell Line, Tumor; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Methylation / drug effects; Methyltransferases / antagonists & inhibitors; Methyltransferases / genetics; Methyltransferases / metabolism; Molecular Sequence Data; RNA Interference; RNA, Small Interfering / metabolism; RNA, Small Interfering / pharmacology
TL;DR:
Data suggest that AS3MT is the major enzyme in the oxidative methylation of inorganic arsenic (iAs) in mammalian species, although an As3MT-independent process may contribute to iAs methylation in human hepatic cells.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2006 journal article
The Cation-Responsive Protein NhaR of Escherichia coli Activates pgaABCD Transcription, Required for Production of the Biofilm Adhesin Poly-β-1,6-N-Acetyl-d-Glucosamine
Journal of Bacteriology, 188(23), 8022–8032.
MeSH headings : Adaptation, Physiological; Adhesins, Bacterial / genetics; Adhesins, Bacterial / metabolism; Antigens, Bacterial / genetics; Base Sequence; Biofilms / growth & development; Cations; DNA, Bacterial / genetics; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; DNA-Binding Proteins / physiology; Escherichia coli / genetics; Escherichia coli / physiology; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Gene Expression Regulation, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Operon / genetics; Promoter Regions, Genetic / physiology; Protein Binding; RNA, Bacterial / genetics; RNA, Messenger / genetics; Sodium Chloride / pharmacology; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription Factors / physiology; Transcription, Genetic
TL;DR:
A novel mechanism for regulation of biofilm formation in response to environmental conditions is defined and an expanded role for NhaR is suggested in promoting bacterial survival.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 30, 2020
2006 journal article
Imaginal Discs, the Genetic and Cellular Logic of Pattern Formation. Lewis I Held, Jr. Cambridge University Press. 2005. 461 pages. ISBN 0 521 01835 8. Price £38. (paperback). (ISBN 0521 58445 0. Price £120. (hardback) published 2002)
Genetical Research, 87(3), 219–219.
Source: Crossref
Added: November 22, 2020
2006 journal article
Pesticide Exposure and Self-reported Parkinson's Disease in the Agricultural Health Study
American Journal of Epidemiology, 165(4), 364–374.
author keywords: case-control studies; herbicides; insecticides; Parkinson disease; pesticides
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Child; Environmental Exposure / adverse effects; Female; Follow-Up Studies; Health Surveys; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Parkinson Disease, Secondary / chemically induced; Parkinson Disease, Secondary / epidemiology; Pesticides / adverse effects; Prevalence; Retrospective Studies; Risk Factors
TL;DR:
It is suggested that exposure to certain pesticides may increase PD risk, and findings for specific chemicals may provide fruitful leads for further investigation.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 3, 2020
2006 journal article
Impairment of spatial learning by estradiol treatment in female mice is attenuated by estradiol exposure during development
Hormones and Behavior, 50(5), 693–698.
author keywords: hippocampus; sex differences; phytoestrogens; aromatase; estrogen receptors; Morris water maze; sexual differentiation
MeSH headings : Animals; Animals, Newborn; Aromatase / genetics; Diet; Estradiol / analogs & derivatives; Estradiol / pharmacology; Female; Male; Maze Learning / drug effects; Mice; Mice, Inbred C57BL; Mice, Knockout; Phytoestrogens / pharmacology; Spatial Behavior / drug effects
TL;DR:
Exposure to estradiol during neonatal development can counteract the deleterious effects of EB on adult spatial learning, and female but not male ArKO mice showed impaired learning compared to WT littermates.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
A model for hormone independent development of sex differences in brain and behavior
Frontiers in Neuroendocrinology, 27(1), 96–97.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2006 journal article
New roles for estrogen receptor β in behavior and neuroendocrinology☆
Frontiers in Neuroendocrinology, 27(2), 217–232.
author keywords: sex differences; hypothalamic pituitary-gonadal axis; hypothalamic-pituitary-adrenal axis; sexual differentiation; serotonin; depression; anxiety; reproduction
MeSH headings : Aggression; Animals; Anxiety / physiopathology; Arousal / physiology; Behavior, Animal / physiology; Discrimination Learning / physiology; Estradiol / metabolism; Estrogen Receptor beta / physiology; Female; Hypothalamo-Hypophyseal System / physiology; Male; Mice; Mice, Knockout; Models, Animal; Pituitary-Adrenal System / physiology; Sex Differentiation / physiology
TL;DR:
The data on functions of the estrogen receptor beta (ERbeta) in both behavior and neuroendocrinology are reviewed to suggest a unique function for ERbeta in sexual differentiation; its activation in male neonates may promote defeminization of sexual behavior.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Roles of estrogen receptors α and β in differentiation of mouse sexual behavior
Neuroscience, 138(3), 921–928.
author keywords: sex differences; gender identity; estrogen receptor; lordosis; sexual orientation; development
MeSH headings : Animals; Estradiol / physiology; Estrogen Receptor alpha / physiology; Estrogen Receptor beta / physiology; Female; Gender Identity; Male; Mice; Sex Characteristics; Sexual Behavior, Animal / physiology; Testosterone / physiology
TL;DR:
In sum, estradiol can have selective effects on distinct behavioral processes via selective interactions with its two receptors, estrogen receptor alpha and estrogen receptor beta.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Pmr1, a Golgi Ca2+/Mn2+-ATPase, is a regulator of the target of rapamycin (TOR) signaling pathway in yeast
Proceedings of the National Academy of Sciences, 103(47), 17840–17845.
MeSH headings : Amino Acid Transport Systems / genetics; Amino Acid Transport Systems / metabolism; Antifungal Agents / metabolism; Calcium-Transporting ATPases / genetics; Calcium-Transporting ATPases / metabolism; Epistasis, Genetic; Gene Expression Regulation, Fungal; Golgi Apparatus / enzymology; Molecular Chaperones / genetics; Molecular Chaperones / metabolism; Protein Kinases / genetics; Protein Kinases / metabolism; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Saccharomyces cerevisiae / cytology; Saccharomyces cerevisiae / enzymology; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism; Signal Transduction / physiology; Sirolimus / metabolism; Transcription Factors / metabolism
TL;DR:
The results establish that Pmr1-dependent Ca2+ and/or Mn2+ ion homeostasis is necessary for TOR signaling, and suggest up-regulation of Npr1 function in the absence of Pmr
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2006 journal article
Biological assessment of bisphenol A degradation in water following direct photolysis and UV advanced oxidation
Chemosphere, 65(7), 1094–1102.
author keywords: endocrine disrupting compounds (EDCs); low-pressure (LP) HgUV lamps; yeast estrogen screen (YES); vitellogenin (VTG); medaka (Oryzias latipes)
MeSH headings : Animals; Benzhydryl Compounds; Estrogen Receptor alpha / metabolism; Estrogens / metabolism; Estrogens / toxicity; Hydrogen Peroxide / chemistry; Larva / drug effects; Male; Oryzias; Oxidation-Reduction; Phenols / chemistry; Phenols / radiation effects; Phenols / toxicity; Photolysis; Ultraviolet Rays; Vitellogenins / metabolism; Water Pollutants, Chemical / chemistry; Water Pollutants, Chemical / radiation effects; Water Pollutants, Chemical / toxicity; Water Purification / methods; Yeasts / drug effects; Yeasts / metabolism
TL;DR:
Investigation of the use of direct photolysis with low-pressure Hg UV lamps and UV+hydrogen peroxide and advanced oxidation process (AOP) for the degradation of a prototypic endocrine disrupter, bisphenol A (BPA), in laboratory water demonstrates that UV alone did not effectively degrade BPA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
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