Works Published in 2017
Displaying all 7 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study
Journal of Allergy and Clinical Immunology, 140(1), 249–256.e14.
Contributors: J. House* , A. Wyss*, J. Hoppin n, M. Richards*, S. Long*, D. Umbach *, P. Henneberger *, L. Beane Freeman
MeSH headings : Aged; Asthma / epidemiology; Case-Control Studies; Environmental Exposure; Farms; Female; Humans; Hypersensitivity, Immediate / blood; Hypersensitivity, Immediate / epidemiology; Immunoglobulin E / blood; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Odds Ratio; Pulmonary Disease, Chronic Obstructive / epidemiology; Smoking / epidemiology
TL;DR:
In a large US farming population, early‐life farm exposures, particularly maternal farming activities while pregnant, were strongly associated with reduced risk of atopy in adults, suggesting that protective associations of early‐ life farming exposures on atopy endure across the life course.
(via Semantic Scholar)
www.jacionline.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: April 11, 2023
2017 journal article
Vagal innervation is required for pulmonary function phenotype in htr4 <sup>–/–</sup> mice
American Journal of Physiology - Lung Cellular and Molecular Physiology, 312(4), L520–L530.
Contributors: J. House* , C. Nichols*, H. Li *, C. Brandenberger *, R. Virgincar*, L. Degraff*, B. Driehuys *, D. Zeldin *, S. London *
MeSH headings : Animals; Genotype; In Vitro Techniques; Lung / innervation; Lung / physiology; Mice, Inbred C57BL; Muscle Contraction / physiology; Phenotype; Pulmonary Ventilation / physiology; Receptors, Serotonin, 5-HT4 / deficiency; Receptors, Serotonin, 5-HT4 / metabolism; Respiration; Respiratory Function Tests; Respiratory Hypersensitivity / physiopathology; Trachea / physiology; Vagotomy; Vagus Nerve / physiology; Vagus Nerve / surgery
TL;DR:
It is reported here that the Htr4-/- phenotype in mouse is dependent on vagal innervation to the lung, and results suggest that HTR4's role in pulmonary function likely relates to neural innervation and control of breathing.
(via Semantic Scholar)
Source: ORCID
Added: April 11, 2023
2017 journal article
Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation
Toxicology and Applied Pharmacology, 329, 249–258.
Contributors: A. Henriquez *, J. House n , D. Miller*, S. Snow *, A. Fisher*, H. Ren*, M. Schladweiler *, A. Ledbetter*, F. Wright n, U. Kodavanti *
MeSH headings : Adrenal Cortex / metabolism; Adrenal Cortex / surgery; Adrenal Medulla / metabolism; Adrenal Medulla / surgery; Adrenalectomy; Animals; Corticosterone / blood; Cytokines / metabolism; Disease Models, Animal; Epinephrine / blood; Gene Expression Regulation; Inflammation Mediators / metabolism; Lung / metabolism; Lung / pathology; Lung Injury / blood; Lung Injury / chemically induced; Lung Injury / genetics; Lung Injury / prevention & control; Male; Neutrophils / metabolism; Oxidative Stress; Ozone; Pneumonia / blood; Pneumonia / chemically induced; Pneumonia / genetics; Pneumonia / pathology; Pneumonia / prevention & control; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats, Inbred WKY; Signal Transduction; Stress, Physiological / genetics; Transcription, Genetic
TL;DR:
It is demonstrated that ozone‐induced lung injury and neutrophilic inflammation require the presence of circulating epinephrine and corticosterone, which transcriptionally regulates signaling mechanisms involved in this response.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Source: ORCID
Added: April 11, 2023
2017 journal article
A pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics
Frontiers in Genetics, 8(NOV).
Contributors: J. House n , F. Grimm*, D. Jima n, Y. Zhou n , I. Rusyn * & F. Wright n
TL;DR:
Using data from induced pluripotent stem cell-derived cardiomyocytes treated with chemicals at varying concentrations, a pipeline is made available for handling expression data generated by TempO-Seq to align reads, clean and normalize raw count data, identify differentially expressed genes, and calculate transcriptomic concentration–response points of departure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2017 journal article
The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: Effects of estradiol and progesterone addback
Translational Psychiatry, 7.
Source: NC State University Libraries
Added: August 6, 2018
2017 review
An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines
[Review of ]. Frontiers in Pharmacology, 8.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Lifetime substance use as a predictor of postpartum mental health
ARCHIVES OF WOMENS MENTAL HEALTH, 20(1), 189–199.
author keywords: Postpartum mental health; Alcohol use; Drug use; Screening
MeSH headings : Adult; Alcohol Drinking / epidemiology; Alcohol Drinking / psychology; Anxiety / epidemiology; Anxiety / psychology; Canada / epidemiology; Depression, Postpartum / diagnosis; Depression, Postpartum / epidemiology; Depression, Postpartum / psychology; Female; Humans; Interviews as Topic; Mood Disorders / epidemiology; Mood Disorders / psychology; Pregnancy; Risk Factors; Stress Disorders, Post-Traumatic / epidemiology; Stress Disorders, Post-Traumatic / psychology; Substance-Related Disorders / epidemiology; Substance-Related Disorders / psychology; Surveys and Questionnaires; Urban Population; Women's Health; Young Adult
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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