Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2025 journal article

Co-occurrence is associated with horizontal gene transfer across marine bacteria independent of phylogeny

The ISME Journal.

co-author countries: Canada 🇨🇦 France 🇫🇷
topics (OpenAlex):
Source: ORCID
Added: December 15, 2025

2025 article

Efficient RNA Folding Simulation via a Structure-Based Single-Site-Per-Nucleotide Model

Thornton, T., & Lin, X. (2025, December 14).

By: T. Thornton & X. Lin

topics (OpenAlex):
Source: ORCID
Added: December 15, 2025

2025 article

Assessing the effect of spaceflight stress on DNA sequence mutation using RNA-sequencing data

By: M. Knight n, C. Doherty n & D. Nielsen n

topics (OpenAlex):
Sources: NC State University Libraries, NC State University Libraries
Added: December 14, 2025

2025 article

MetaStrainer: Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples.

By: H. Sharaf n & L. Bobay n

topics (OpenAlex):
Sources: NC State University Libraries, NC State University Libraries
Added: December 12, 2025

2025 article

MetaStrainer: Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples.

By: H. Sharaf n & L. Bobay n

topics (OpenAlex):
Sources: NC State University Libraries, NC State University Libraries
Added: December 12, 2025

2025 article

Linking chemical data from the Comparative Toxicogenomics Database with adverse outcome pathways from the AOP-Wiki: a mechanistic data-oriented approach to help inform environmental health

By: A. Davis*, T. Wiegers*, D. Sciaky*, F. Barkalow*, B. Wyatt*, J. Wiegers*, R. McMorran*, S. Abrar* ...

topics (OpenAlex): Autism Spectrum Disorder Research; Health, Environment, Cognitive Aging; Click Chemistry and Applications
Sources: NC State University Libraries, NC State University Libraries
Added: November 19, 2025

2025 article

mIDEA: An Interpretable Structure–Sequence Model for Methylation-Dependent Protein–DNA Binding Sensitivity

Zhang, Y., Li, R., Zhong, J., & Lin, X. (2025, November 16).

topics (OpenAlex): Epigenetics and DNA Methylation; Cancer-related gene regulation; Machine Learning in Bioinformatics
Source: ORCID
Added: November 16, 2025

2025 journal article

Introgression impacts the evolution of bacteria, but species borders are rarely fuzzy

Nature Communications.

co-author countries: Canada 🇨🇦
topics (OpenAlex): Evolution and Genetic Dynamics; Microbial Community Ecology and Physiology; Bacterial Genetics and Biotechnology
Source: ORCID
Added: November 13, 2025

2025 article

Active regulation of the epidermal growth factor receptor by the membrane bilayer

Srinivasan, S., Lin, X., Chen, X., Regmi, R., Zhang, B., & Schlau-Cohen, G. S. (2025, October 13).

topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HER2/EGFR in Cancer Research; Receptor Mechanisms and Signaling
Source: ORCID
Added: October 13, 2025

2025 article

Active regulation of the epidermal growth factor receptor by the membrane bilayer

Srinivasan, S., Lin, X., Chen, X., Regmi, R., Zhang, B., & Schlau-Cohen, G. S. (2025, October 13).

topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HER2/EGFR in Cancer Research; Receptor Mechanisms and Signaling
Source: ORCID
Added: October 13, 2025

2025 article

IRIS Integrates Sparse Sequence, Experimental, and AI-Predicted Structures for Protein-RNA Affinity Prediction and Motif Discovery

Rosa, E. C., Zhang, Y., & Lin, X. (2025, September 16).

By: E. Rosa, Y. Zhang & X. Lin*

topics (OpenAlex): Machine Learning in Bioinformatics; RNA and protein synthesis mechanisms; Genomics and Phylogenetic Studies
Source: ORCID
Added: September 16, 2025

2025 article

Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model

Song, Z., Tryndyak, V. P., Willett, R. A., Pogribny, I. P., Rusyn, I., & Wright, F. A. (2025, August 28). TOXICOLOGICAL SCIENCES.

author keywords: liver; steatohepatitis; fibrosis
topics (OpenAlex): Liver Disease Diagnosis and Treatment; Hepatitis B Virus Studies; Endoplasmic Reticulum Stress and Disease
Source: Web Of Science
Added: September 8, 2025

2025 journal article

Two-body triton photodisintegration and Wigner-SU(4) symmetry

PHYSICAL REVIEW C, 112(2).

By: X. Lin & J. Vanasse

topics (OpenAlex): Molecular spectroscopy and chirality; Advanced Chemical Physics Studies
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 article

Active regulation of the epidermal growth factor receptor by the membrane bilayer

Srinivasan, S., Lin, X., Chen, X., Regmi, R., Zhang, B., & Schlau-Cohen, G. S. (2025, August 18).

topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HER2/EGFR in Cancer Research; Receptor Mechanisms and Signaling; Lipid Membrane Structure and Behavior
Source: ORCID
Added: August 19, 2025

2025 article

Genomic Evaluation of Canine Prostatic Carcinomas as a Model for the Human Disease

Thomas, R., Luff, J. A., Dickey, A. N., Dillon, M. N., Livingston, I. G., Schrag, C. A., … Breen, M. (2025, July 23). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.

By: R. Thomas n, J. Luff n, A. Dickey n, M. Dillon n, I. Livingston n, C. Schrag n, S. Suter n, M. Breen n

author keywords: adenocarcinoma; DNA copy number variations; dogs; mutation; prostatic neoplasms; urologic neoplasms
topics (OpenAlex): Veterinary Oncology Research; Veterinary Medicine and Surgery; Human-Animal Interaction Studies; Urological Disorders and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 28, 2025

2025 journal article

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

GENOME RESEARCH, 35(7), 1485–1502.

MeSH headings : Humans; Quantitative Trait Loci; Liver / metabolism; Chromatin / genetics; Chromatin / metabolism; Genome-Wide Association Study; Gene Expression Regulation; Transcription Factors / metabolism; Binding Sites; Polymorphism, Single Nucleotide
topics (OpenAlex): Epigenetics and DNA Methylation; Genomics and Chromatin Dynamics; Genetics and Neurodevelopmental Disorders
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice☆

TOXICOLOGY AND APPLIED PHARMACOLOGY, 502.

co-author countries: Canada 🇨🇦
author keywords: Mice; MASH; Liver Pathology; Transcriptomics; Machine Leaning Pathologist Assistance
MeSH headings : Animals; Male; Female; Mice; Disease Models, Animal; Diet, High-Fat / adverse effects; Liver / pathology; Liver / metabolism; Transcriptome; Gene Expression Profiling / methods; Collaborative Cross Mice; Fatty Liver / genetics; Fatty Liver / pathology; Fatty Liver / metabolism; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / pathology
topics (OpenAlex): Liver Disease Diagnosis and Treatment; Endoplasmic Reticulum Stress and Disease; Hepatocellular Carcinoma Treatment and Prognosis
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Interpretable protein-DNA interactions captured by structure-sequence optimization

ELife.

By: Y. Zhang n, I. Silvernail n, Z. Lin n & X. Lin n

topics (OpenAlex): RNA and protein synthesis mechanisms; Genomics and Chromatin Dynamics; DNA and Nucleic Acid Chemistry
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: July 17, 2025

2025 journal article

Conditional knockout of C/EBPβ in epidermis results in dysregulated lipid biosynthesis and a defect in skin barrier function

PLOS ONE, 20(6).

By: K. Mills n, M. Doyle n, J. House n, J. Witherspoon n, D. Krakko n, W. Stutts n, J. Chappel n, J. Hall n, E. Baker n, R. Smart n

Ed(s): S. Raza

MeSH headings : Animals; Epidermis / metabolism; Mice; Mice, Knockout; Lipid Metabolism / genetics; Lipids / biosynthesis; CCAAT-Enhancer-Binding Proteins / genetics; CCAAT-Enhancer-Binding Proteins / metabolism; Keratinocytes / metabolism; Lipogenesis / genetics; Lipidomics
topics (OpenAlex): melanin and skin pigmentation; Retinoids in leukemia and cellular processes; Plant Molecular Biology Research
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 25, 2025

2025 journal article

Characterizing DNA recognition preferences of transcription factors using global couplings and high-throughput sequencing

NUCLEIC ACIDS RESEARCH, 53(12).

MeSH headings : Transcription Factors / metabolism; Humans; Binding Sites; DNA / metabolism; DNA / chemistry; High-Throughput Nucleotide Sequencing / methods; Chromatin Immunoprecipitation Sequencing; Protein Binding; SELEX Aptamer Technique; Genome, Human; Sequence Analysis, DNA
topics (OpenAlex): Genomics and Chromatin Dynamics; RNA and protein synthesis mechanisms; RNA Research and Splicing
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 15, 2025

2025 journal article

HAP-SAMPLE2: data-based resampling for association studies with admixture

BIOINFORMATICS, 41(6).

By: G. Sun n, B. Ting n, F. Wright n & Y. Zhou n

Ed(s): J. Kelso

MeSH headings : Software; Humans; Genome-Wide Association Study / methods; Genotype; Genetic Association Studies / methods; Polymorphism, Single Nucleotide; Genetics, Population; Phenotype
topics (OpenAlex): Data Mining Algorithms and Applications
Sources: ORCID, Web Of Science
Added: June 11, 2025

2025 article

Interpretable Protein-DNA Interactions Captured by Structure-Sequence Optimization

Zhang, Y., Silvernail, I., Lin, Z., & Lin, X. (2025, June 9).

By: Y. Zhang n, I. Silvernail n, Z. Lin n & X. Lin n

topics (OpenAlex): RNA and protein synthesis mechanisms; Genomics and Chromatin Dynamics; RNA modifications and cancer
Source: ORCID
Added: June 9, 2025

2025 journal article

Asian diversity in human immune cells

CELL, 188(8).

co-author countries: France 🇫🇷 India 🇮🇳 Italy 🇮🇹 Japan 🇯🇵 Korea (Republic of) 🇰🇷 Singapore 🇸🇬 Thailand 🇹🇭
MeSH headings : Humans; Asian People / genetics; Single-Cell Analysis; Female; Male; Genetic Variation; Asia; Adult; Middle Aged
topics (OpenAlex): Immune Cell Function and Interaction; Immune responses and vaccinations; T-cell and B-cell Immunology
Source: Web Of Science
Added: May 27, 2025

2025 journal article

The integration of quantitative trait locus mapping and transcriptome studies reveals candidate genes for water stress response in St. Augustinegrass

BMC Plant Biology, 25(1).

author keywords: QTL mapping; Transcriptome; Drought stress; St. Augustinegrass
MeSH headings : Quantitative Trait Loci / genetics; Chromosome Mapping; Transcriptome; Droughts; Genes, Plant; Gene Expression Profiling; Polymorphism, Single Nucleotide; Stress, Physiological / genetics; Genotype
topics (OpenAlex): Turfgrass Adaptation and Management; Plant and Fungal Interactions Research; Plant Disease Resistance and Genetics
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: May 27, 2025

2025 journal article

Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes

International Journal of Molecular Sciences.

MeSH headings : Cytochrome P-450 Enzyme Inhibitors / pharmacology; Cytochrome P-450 Enzyme Inhibitors / chemistry; Humans; Cytochrome P-450 Enzyme System / metabolism; Cytochrome P-450 Enzyme System / chemistry; Small Molecule Libraries / pharmacology; Small Molecule Libraries / chemistry
topics (OpenAlex): Pharmacogenetics and Drug Metabolism; Cancer Treatment and Pharmacology; Computational Drug Discovery Methods
Source: ORCID
Added: May 22, 2025

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