Works Published in 1985
Displaying 1 work
Sorted by most recent date added to the index first, which may not be the same as publication date order.
1985 journal article
Effect of ascorbate on covalent binding of benzene and phenol metabolites to isolated tissue preparations
Toxicology and Applied Pharmacology, 77(2), 334–343.
MeSH headings : Animals; Ascorbic Acid / physiology; Benzene / metabolism; Binding Sites; Binding, Competitive; Bone Marrow / metabolism; Glutathione / physiology; Guinea Pigs; In Vitro Techniques; Lung / metabolism; Male; Microsomes, Liver / metabolism; NAD(P)H Dehydrogenase (Quinone); Phenols / metabolism; Quinone Reductases / physiology
TL;DR:
The results indicate that different metabolites are responsible for a portion of the covalent binding depending upon the substrate employed, and how the dietary intake of ascorbate can result in a differential response to a potentially toxic event in vitro.
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Added: April 9, 2022
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