Works Published in 2020
Displaying all 15 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 journal article
Associations between Maternal Cadmium Exposure with Risk of Preterm Birth and Low after Birth Weight Effect of Mediterranean Diet Adherence on Affected Prenatal Outcomes
TOXICS, 8(4).
author keywords: cadmium; heavy metals; birth weight; preterm birth; diet pattern; Mediterranean diet; pregnancy
TL;DR:
The findings suggest that adherence to a Mediterranean dietary pattern during pregnancy may not mitigate cadmium exposure effects, and that larger studies are required to clarify these findings.
(via Semantic Scholar)
www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 19, 2021
2020 journal article
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
GENOME MEDICINE, 12(1).
author keywords: Body mass index; Childhood obesity; DNA methylation; Epigenetics
MeSH headings : Adolescent; Body Mass Index; Child; Child, Preschool; CpG Islands; Cross-Sectional Studies; DNA Methylation; Epigenesis, Genetic; Epigenome; Female; Fetal Blood; Humans; Male; Obesity / genetics; Parturition; Pediatric Obesity / genetics; Pregnancy
TL;DR:
The strength of the associations of DNA methylation at the 187 CpGs previously identified to be associated with adult BMI, increased with advancing age across childhood and adolescence in the authors' analyses, compatible with the hypothesis thatDNA methylation differences are mostly a consequence rather than a cause of obesity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis
TRANSLATIONAL PSYCHIATRY, 10(1).
MeSH headings : Adolescent; Attention Deficit Disorder with Hyperactivity / genetics; Child; Child, Preschool; DNA Methylation; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Pregnancy; Prospective Studies; Schools
TL;DR:
Evidence is found that DNA methylation at birth is associated with ADHD, and future studies are needed to confirm the utility of methylation variation as biomarker and its involvement in causal pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 21, 2020
2020 journal article
Replicated umbilical cord blood DNA methylation loci associated with gestational age at birth
EPIGENETICS, 15(11), 1243–1258.
author keywords: DNA methylation; gene expression; data integration; replication; preterm birth; gestational age at birth; umbilical cord blood; PREG study; NEST study; innate immunity; inflammation
MeSH headings : Adult; CpG Islands; DNA Methylation; Epigenome; Female; Fetal Blood / metabolism; Genetic Loci; Genome-Wide Association Study; Gestational Age; Humans; Immunity, Innate / genetics; Infant, Newborn; Infant, Premature; Male; Premature Birth / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: November 16, 2020
2020 journal article
Maternal Employment and Infant BMI z Score in a US Birth Cohort
OBESITY, 28(12), 2389–2396.
MeSH headings : Adult; Anthropometry; Body Mass Index; Cohort Studies; Employment / methods; Female; Humans; Infant, Newborn; Longitudinal Studies; Male; Mothers; United States
TL;DR:
The purpose of this study was to investigate the association between maternal employment and infant BMI z score.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 9, 2020
2020 journal article
Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing
NUCLEIC ACIDS RESEARCH, 48(15), 8349–8359.
MeSH headings : Animals; Cell Differentiation / genetics; Chromatin / genetics; CpG Islands / genetics; DNA Methylation / genetics; Epigenesis, Genetic; Genome / genetics; Histone Code / genetics; Humans; Promoter Regions, Genetic; Protein Processing, Post-Translational / genetics; Pseudogenes / genetics; RNA Precursors / genetics; RNA Precursors / metabolism; Transcription, Genetic
TL;DR:
It is suggested that iCGI transcription, rather than H3K36me3 or DNA methylation, interfere with host gene transcription and pre-mRNA processing genomewide and contributes to the spatiotemporal diversification of both the transcriptome and proteome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2020
2020 journal article
Metabolite Profiling Reveals Predictive Biomarkers and the Absence of beta-Methyl Amino-L-alanine in Plasma from Individuals Diagnosed with Amyotrophic Lateral Sclerosis
JOURNAL OF PROTEOME RESEARCH, 19(8), 3276–3285.
author keywords: amyotrophic lateral sclerosis; biomarkers; BMAA; CZE-MS/MS; metabolites; plasma
MeSH headings : Alanine; Amyotrophic Lateral Sclerosis / diagnosis; Biomarkers; Female; Humans; Male; Mass Spectrometry; Metabolome
TL;DR:
The plasma metabolome of 134 patients diagnosed with sporadic amyotrophic lateral sclerosis and 118 individuals deemed healthy was profiled, and two models using the metabolite abundances were developed for the separation of ALS and healthy samples and the prediction of disease progression based on the ALS functional rating score.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 14, 2020
2020 journal article
Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina
ENVIRONMENTAL HEALTH PERSPECTIVES, 128(7).
MeSH headings : Adult; Alkanesulfonic Acids; Caprylates; Child; Drinking Water; Environmental Exposure / statistics & numerical data; Female; Fluorocarbons / analysis; Fluorocarbons / blood; Humans; Male; North Carolina; Nutrition Surveys; Rivers; Water Pollutants, Chemical / analysis
TL;DR:
Poorly understood fluoroethers released into the Cape Fear River by a fluorochemical manufacturing facility were detected in blood samples from Wilmington, North Carolina, residents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020
2020 article
Expression of UDP Glucuronosyltransferases2B15and2B17is associated with methylation status in prostate cancer cells
EPIGENETICS.
MeSH headings : DNA Methylation; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase / genetics; Glucuronosyltransferase / metabolism; Humans; Male; Minor Histocompatibility Antigens / genetics; Prostatic Neoplasms / genetics
TL;DR:
The results taken together suggest that hypomethylation of the UGT2B15 and UGT 2B17 genes contributes to increased risk of prostate cancer and may provide a putative biomarker or epigenetic target for chemotherapeutics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 17, 2020
2020 journal article
Effect of Prenatal Smoke Exposure on Birth Weight: The Moderating Role of Maternal Depressive Symptoms
NICOTINE & TOBACCO RESEARCH, 22(1), 40–47.
MeSH headings : Adolescent; Adult; Biomarkers / blood; Birth Weight / drug effects; Cotinine / blood; Depression / complications; Female; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Maternal Exposure / adverse effects; Pregnancy; Prenatal Exposure Delayed Effects / etiology; Prenatal Exposure Delayed Effects / pathology; Prospective Studies; Risk Factors; Tobacco Smoke Pollution / adverse effects; Young Adult
TL;DR:
Prenatal cotinine was a significant predictor of birth weight only in the context of maternal depressive symptoms, suggesting prenatal smoke exposure has a greater negative effect on birth weight for women endorsing co-occurring depressive symptoms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 27, 2020
2020 journal article
Peptide variability and signatures associated with disease progression in CSF collected longitudinally from ALS patients
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(22), 5465–5475.
author keywords: Amyotrophic lateral sclerosis; Cerebrospinal fluid; Longitudinal modeling; Proteomics; Biomarker
MeSH headings : Aged; Amyotrophic Lateral Sclerosis / cerebrospinal fluid; Chromatography, Liquid / methods; Disease Progression; Female; Humans; Longitudinal Studies; Male; Middle Aged; Peptides / cerebrospinal fluid; Proteomics; Tandem Mass Spectrometry / methods
TL;DR:
Overall, the CSF protein abundances are tightly regulated with the intra-individual variability contributing just 4% to the overall variance and the association of inflammation with rate of disease progression is explored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: July 13, 2020
2020 journal article
The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort
CURRENT MEDICAL RESEARCH AND OPINION, 36(6), 1025–1032.
author keywords: Anesthesia; opioid analgesics; asthma; children; sex-specific
MeSH headings : Adult; Anesthesia, Epidural / adverse effects; Anesthesia, Obstetrical / adverse effects; Asthma / etiology; Cesarean Section / adverse effects; Child; Child, Preschool; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Logistic Models; Male; Pregnancy; Retrospective Studies
TL;DR:
The data suggest that peripartum exposure to neuraxial anesthesia may reduce the risk of childhood asthma primarily in males.
(via Semantic Scholar)
Source: Web Of Science
Added: June 22, 2020
2020 journal article
Timing of complementary feeding is associated with gut microbiota diversity and composition and short chain fatty acid concentrations over the first year of life
BMC MICROBIOLOGY, 20(1).
author keywords: Microbiome; Pediatrics; Weaning; Complementary feeding; Butyrate; Metabolites
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; DNA, Bacterial / genetics; DNA, Ribosomal / genetics; Fatty Acids, Volatile / analysis; Feces / chemistry; Feces / microbiology; Female; Gastrointestinal Microbiome; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Mothers; Phylogeny; Prospective Studies; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA / methods; Time Factors
TL;DR:
The findings are consistent with the hypothesis that early (vs. later) introduction to complementary foods is associated with altered gut microbiota composition and butyric acid concentrations measured in stool until at least 1 year of age.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 6, 2020
2020 journal article
Associations between attention deficit hyperactivity disorder symptoms and eating behaviors in early childhood
PEDIATRIC OBESITY, 15(7).
author keywords: ADHD; childhood; eating behaviors; latent change score; self-regulation
MeSH headings : Adolescent; Adult; Attention Deficit Disorder with Hyperactivity / psychology; Child; Child, Preschool; Cross-Sectional Studies; Feeding Behavior / psychology; Female; Humans; Hyperphagia / psychology; Male; Pediatric Obesity / etiology; Pediatric Obesity / prevention & control; Prospective Studies; Young Adult
TL;DR:
Attention‐deficit/hyperactivity disorder symptoms have been linked with eating behaviors and obesity adolescence and young adulthood, but little is known about whether these associations occur during early childhood and few studies have examined these associations prospectively.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: March 23, 2020
2020 journal article
Early Child Care and Weight Status in a Cohort of Predominantly Black Infants in the Southeastern United States
CHILDHOOD OBESITY, 16(2), 122–128.
author keywords: birth cohort; child care; infancy; obesity
MeSH headings : Black or African American / statistics & numerical data; Body Weight / physiology; Female; Humans; Infant; Infant Care / statistics & numerical data; Infant, Newborn; Longitudinal Studies; Male; North Carolina; Pediatric Obesity
TL;DR:
Although the associations of time infants spent in child care, both overall and in different types of care, with weight status at 6 and 12 months were examined, combination care and relative care during infancy were associated with higher weight.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 25, 2019
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