Works Published in 2014
Displaying works 61 - 80 of 259 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 conference paper
Tradeoffs in Public Acceptance and Water Savings in Using Reclaimed Water for Irrigation Applications
World Environmental and Water Resources Congress 2014. Presented at the World Environmental and Water Resources Congress 2014.
Event: World Environmental and Water Resources Congress 2014
Sources: Crossref, NC State University Libraries
Added: June 6, 2020
2014 journal article
Sensitivity of blood lead-air lead slope factors to particle size distribution of ambient air lead
Environmental Science and Technology, 48, 1263–1270.
Source: NC State University Libraries
Added: May 8, 2020
2014 journal article
Temporal proteomic analysis reveals defects in small-intestinal development of porcine fetuses with intrauterine growth restriction
The Journal of Nutritional Biochemistry, 25(7), 785–795.
author keywords: Intrauterine growth restriction; Fetus; Intestine; Development; Pig
MeSH headings : Animals; Animals, Newborn; Female; Fetal Growth Retardation / metabolism; Gestational Age; Intestinal Mucosa / metabolism; Intestine, Small / embryology; Intestine, Small / metabolism; Pregnancy; Proteome / metabolism; Swine
TL;DR:
These findings provide the first evidence for altered proteomes in the small intestine of IUGR fetuses, thereby predisposing the gut to metabolic defects during gestation and neonatal periods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Putrescine Stimulates the mTOR Signaling Pathway and Protein Synthesis in Porcine Trophectoderm Cells
Biology of Reproduction, 91(5).
author keywords: mTOR; placental cells; protein synthesis; putrescine
MeSH headings : Animals; Cell Proliferation / drug effects; Cells, Cultured; Ectoderm / drug effects; Ectoderm / metabolism; Eflornithine / pharmacology; Female; Pregnancy; Protein Biosynthesis / drug effects; Putrescine / pharmacology; Signal Transduction / drug effects; Swine; TOR Serine-Threonine Kinases / metabolism; Trophoblasts / drug effects; Trophoblasts / metabolism; Up-Regulation / drug effects
TL;DR:
Results indicate that putrescine promotes cell proliferation and protein synthesis in a dose- and time-dependent manner, which was inhibited by difluoro-methylornithine (an inhibitor of ornithine decarboxylase), and reveals a novel and important role for putresCine in regulating the mTOR signaling pathway in porcine placental cells.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Arginine Decarboxylase and Agmatinase: An Alternative Pathway for De Novo Biosynthesis of Polyamines for Development of Mammalian Conceptuses
Biology of Reproduction, 90(4).
author keywords: agmatine; development; polyamines; sheep; trophectoderm
MeSH headings : Agmatine / metabolism; Animals; Carboxy-Lyases / metabolism; Cationic Amino Acid Transporter 1 / genetics; Cationic Amino Acid Transporter 1 / metabolism; Citrulline / metabolism; Embryo Implantation / physiology; Embryonic Development / physiology; Female; Mammals; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Ornithine / metabolism; Ornithine Decarboxylase / genetics; Ornithine Decarboxylase / metabolism; Pregnancy; Pregnancy, Animal / physiology; Putrescine / biosynthesis; Sheep; Spermidine / biosynthesis; Spermine / biosynthesis; Ureohydrolases / metabolism
TL;DR:
It is concluded that the majority of polyamine synthesis is by the conventional ODC1-dependent pathway (arginine-ornithine-putrescine) and that deficiencies in O DC1 result in increased activity of the rescue ADC/AGMAT-dependent route for production of polyamines.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Functional role of arginine during the peri‐implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm
The FASEB Journal, 28(7), 2852–2863.
author keywords: development; sheep; morpholino
MeSH headings : Amino Acids / genetics; Amino Acids / metabolism; Animals; Arginine / genetics; Arginine / metabolism; Cationic Amino Acid Transporter 1 / genetics; Cationic Amino Acid Transporter 1 / metabolism; Embryo Implantation / genetics; Embryo Implantation / physiology; Endometrium / metabolism; Endometrium / physiology; Female; Gene Expression Regulation, Developmental / genetics; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Ornithine Decarboxylase / genetics; Ornithine Decarboxylase / metabolism; Polyamines / metabolism; Pregnancy; RNA, Messenger / genetics; Sheep / genetics; Sheep / metabolism; Uterus / metabolism; Uterus / physiology
TL;DR:
An in vivo morpholino antisense oligonucleotide (MAO)‐mediated knockdown of SLC7A1 mRNA, the arginine transporter in ovine conceptus trophectoderm (Tr), resulted in retarded conceptus development and abnormal function compared to MAO control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Functional Role of Arginine During the Peri-implantation Period of Pregnancy. II. Consequences of Loss of Function of Nitric Oxide Synthase NOS3 mRNA in Ovine Conceptus Trophectoderm
Biology of Reproduction, 91(3).
author keywords: development; morpholino; nitric oxide; nitric oxide synthase
MeSH headings : Animals; Animals, Inbred Strains; Arginine / metabolism; Blastocyst / cytology; Blastocyst / drug effects; Blastocyst / metabolism; Blastocyst / pathology; Cationic Amino Acid Transporter 1 / metabolism; Embryo Implantation / drug effects; Embryo, Mammalian / cytology; Embryo, Mammalian / drug effects; Embryo, Mammalian / metabolism; Embryo, Mammalian / pathology; Embryonic Development / drug effects; Extraembryonic Membranes / cytology; Extraembryonic Membranes / drug effects; Extraembryonic Membranes / metabolism; Extraembryonic Membranes / pathology; Female; Fetal Growth Retardation / chemically induced; Fetal Growth Retardation / metabolism; Fetal Growth Retardation / pathology; Immunohistochemistry; Interferon Type I / metabolism; Morpholinos / pharmacology; Nitric Oxide Synthase Type III / antagonists & inhibitors; Nitric Oxide Synthase Type III / genetics; Nitric Oxide Synthase Type III / metabolism; Pregnancy; Pregnancy Maintenance / drug effects; Pregnancy Proteins / metabolism; RNA, Messenger / antagonists & inhibitors; RNA, Messenger / metabolism; Sheep, Domestic; Texas
TL;DR:
The data suggest that NOS3 is the key enzyme for NO production by conceptus Tr and that this protein also regulates the availability of arginine in conceptus tissues for synthesis of polyamines that are essential for conceptus survival and development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Analysis of polyamines in biological samples by HPLC involving pre-column derivatization with o-phthalaldehyde and N-acetyl-l-cysteine
Amino Acids, 46(6), 1557–1564.
author keywords: Polyamines; Derivatization; o-Phthalaldehyde; N-Acetyl-L-cysteine; HPLC
MeSH headings : Acetylcysteine / chemistry; Animals; Cells, Cultured / chemistry; Chromatography, High Pressure Liquid / methods; Plants / chemistry; Polyamines / analysis; Reproducibility of Results; Spectrometry, Fluorescence / methods; o-Phthalaldehyde / chemistry
TL;DR:
The HPLC method is highly sensitive, specific, accurate, easily automated, and capable for the analysis of samples with different characteristics and small volume/amount, and provides a useful research tool for studying the biochemistry, physiology, and pharmacology of polyamines and related substances.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Environmental factors affecting pregnancy: Endocrine disrupters, nutrients and metabolic pathways
Molecular and Cellular Endocrinology, 398(1-2), 53–68.
author keywords: Arginine; Glucose; Secreted phosphoprotein 1; Pregnancy; Endocrine Disrupter
MeSH headings : Agmatine / metabolism; Animals; Arginine / metabolism; Embryo Implantation; Embryonic Development; Endocrine Disruptors / adverse effects; Environment; Environmental Exposure / adverse effects; Estrogens / adverse effects; Female; Gene Expression Regulation, Developmental; High Fructose Corn Syrup / adverse effects; Humans; Infertility / chemically induced; Insulin Resistance; Metabolic Diseases / chemically induced; Nitric Oxide / biosynthesis; Phosphoproteins / metabolism; Polyamines / metabolism; Pregnancy; Prenatal Exposure Delayed Effects; Progestins / adverse effects
TL;DR:
Uterine adenogenesis, a unique post-natal event in mammals, is vulnerable to endocrine disruption by estrogens and progestins resulting in infertility or reduced prolificacy, and novel pathways for nutrient metabolism during pregnancy can improve survival and growth.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Improving amino acid nutrition to prevent intrauterine growth restriction in mammals
Amino Acids, 46(7), 1605–1623.
author keywords: Amino acids; Fetus; Intervention; IUGR; Nutrition; Placenta; Pregnancy
MeSH headings : Amino Acids / metabolism; Amino Acids / pharmacology; Animals; Arginine / metabolism; Arginine / pharmacology; Female; Fetal Growth Retardation / metabolism; Fetal Growth Retardation / prevention & control; Fetal Growth Retardation / veterinary; Mammals; Maternal Nutritional Physiological Phenomena; Placental Circulation; Pregnancy
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 4, 2020
2014 journal article
Mercury bioaccumulation in Southern Appalachian birds, assessed through feather concentrations
Ecotoxicology, 23(2), 304–316.
author keywords: Mercury; Songbirds; Appalachian Mountains; Nitrogen-15 stable isotope; Trophic position; Terrestrial
MeSH headings : Animals; Birds; Environmental Monitoring / methods; Environmental Pollutants / analysis; Feathers / chemistry; Female; Linear Models; Male; Mercury / analysis
TL;DR:
It is demonstrated that mercury is biomagnifying in birds within this terrestrial mountainous system, and further research is warranted for animals foraging at higher trophic levels, particularly those associated with aquatic environments downslope from montane areas receiving high mercury deposition.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2014 journal article
TAK1 kinase switches cell fate from apoptosis to necrosis following TNF stimulation
The Journal of Cell Biology, 204(4), 607–623.
MeSH headings : Adaptor Proteins, Signal Transducing / physiology; Animals; Apoptosis / drug effects; Blotting, Western; Cell Cycle; Chemical and Drug Induced Liver Injury / metabolism; Chemical and Drug Induced Liver Injury / pathology; Flow Cytometry; Humans; Immunoprecipitation; Integrases / metabolism; Lipopolysaccharides / toxicity; MAP Kinase Kinase Kinases / physiology; Mice; Mice, Knockout; Necrosis; Phosphorylation; RNA, Small Interfering / genetics; Receptor-Interacting Protein Serine-Threonine Kinases / antagonists & inhibitors; Receptor-Interacting Protein Serine-Threonine Kinases / physiology; Signal Transduction; Tumor Necrosis Factor-alpha / pharmacology
TL;DR:
Activation of the TAK1 kinase drives RIPK3-dependent necrosis and inhibits apoptosis downstream of TNF-α stimulation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 24, 2020
2014 journal article
Aerosolized MANS and BIO-11006 Peptides Inhibit Lung Cancer Metastasis in SCID Mice
International Journal of Radiation Oncology*Biology*Physics, 90(5), S51.
TL;DR:
Almost 50% of lung adenocarcinoma of all stages harbored an identifiable driver mutation, and amongst the authors' cases, AA patients had a higher frequency of dual mutations than in other patient populations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 21, 2020
2014 journal article
A microarray for assessing transcription from pelagic marine microbial taxa
The ISME Journal, 8(7), 1476–1491.
author keywords: marine; microbial; microarray; transcription; molecular
MeSH headings : Alphaproteobacteria / classification; Alphaproteobacteria / genetics; Aquatic Organisms; Archaea / classification; Archaea / genetics; Genetic Markers; Genetic Variation; Iron / metabolism; Metagenome; Microbial Consortia; Oceans and Seas; Oligonucleotide Array Sequence Analysis; Phylogeny; Prochlorococcus / classification; Prochlorococcus / genetics; Synechococcus / classification; Synechococcus / genetics; Transcription, Genetic; Viruses / classification; Viruses / genetics
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2014 journal article
Gammaproteobacterial diazotrophs and nifH gene expression in surface waters of the South Pacific Ocean
The ISME Journal, 8(10), 1962–1973.
author keywords: Crocosphaera; diel cycle; nifH; nitrogen cycle; transcription; UCYN-A
MeSH headings : Cyanobacteria / genetics; Gammaproteobacteria / genetics; Gammaproteobacteria / metabolism; Gene Dosage; Gene Expression; Nitrogen Fixation / genetics; Oxidoreductases / genetics; Oxidoreductases / metabolism; Pacific Ocean; Phylogeny; Seawater / microbiology; Temperature; Water Microbiology
TL;DR:
It is suggested that γ-24774A11 could be one of the most important heterotrophic (or photoheterotrophic) diazotrophs and may need to be considered in future N budget estimates and models.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2014 journal article
Heritability and genomics of gene expression in peripheral blood
Nature Genetics, 46(5), 430–437.
MeSH headings : Blood / metabolism; Gene Expression Profiling; Gene Expression Regulation / genetics; Genotype; Humans; Inheritance Patterns / genetics; Likelihood Functions; Netherlands; Polymorphism, Single Nucleotide / genetics; Quantitative Trait Loci / genetics
TL;DR:
Gen expression profiles in 2,752 twins were assessed, using a classic twin design, to quantify expression heritability and quantitative trait loci (eQTLs) in peripheral blood, providing a new resource toward understanding the genetic control of transcription.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 5, 2020
2014 journal article
Hierarchical Genetic Analysis of German Cockroach (Blattella germanica) Populations from within Buildings to across Continents
PLoS ONE, 9(7), e102321.
Ed(s): Z. Adelman
MeSH headings : Animals; Bayes Theorem; Blattellidae / genetics; Cluster Analysis; DNA, Mitochondrial / genetics; Genetic Variation; Housing; Microsatellite Repeats / genetics; Spatial Analysis; Species Specificity
TL;DR:
The German cockroach (Blattella germanica) is a widespread urban invader that can actively disperse within buildings but is spread solely by human-mediated dispersal over longer distances; however, its population structure is poorly understood.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities
(OpenAlex)
15. Life on Land
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 28, 2020
2014 journal article
Sugar aversion: A newly-acquired adaptive change in gustatory receptor neurons in the German cockroach
Hikaku Seiri Seikagaku(Comparative Physiology and Biochemistry), 31(4), 220–230.
Sources: Crossref, NC State University Libraries
Added: January 28, 2020
2014 journal article
In Vitro Neutrophil Migration Requires Protein Kinase C-Delta (δ-PKC)-Mediated Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Phosphorylation
Inflammation, 38(3), 1126–1141.
author keywords: neutrophil; chemotaxis; adhesion; migration; innate immunity; PKC signaling
MeSH headings : Acetophenones / pharmacology; Benzopyrans / pharmacology; Cell Adhesion / immunology; Cell Movement; Cells, Cultured; Enzyme Inhibitors / pharmacology; Humans; Inflammation / immunology; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; N-Formylmethionine Leucyl-Phenylalanine / metabolism; Neutrophil Activation / immunology; Neutrophil Infiltration / immunology; Neutrophils / immunology; Phosphorylation; Protein Isoforms / antagonists & inhibitors; Protein Isoforms / metabolism; Protein Kinase C-delta / antagonists & inhibitors; Protein Kinase C-delta / metabolism
TL;DR:
It is concluded that δ-PKC-mediated MARCKS phosphorylation is essential for human neutrophil migration and adhesion in vitro, and this results implicate €1,000,000 phosphorylated actin binding protein and protein kinase C (PKC) as a key step in the inflammatory response of neutrophils.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 19, 2020
2014 journal article
Variance estimation and kriging prediction for a class of non-stationary spatial models
Statistica Sinica.
author keywords: Bandwidth selection; heteroscedasticity; K-fold cross-validation; local polynomial regression; rates of convergence; variance function
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
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