Works Published in 2019

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Displaying works 161 - 180 of 225 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 journal article

Robust and Accurate Inference via a Mixture of Gaussian and Student's t Errors

JOURNAL OF COMPUTATIONAL AND GRAPHICAL STATISTICS, 28(2), 415–426.

author keywords: Gaussian process; Gibbs sampling; Hierarchical model; Huber's M-estimator; Linear mixed model; Outlier; Time series
TL;DR: A mixture error assumption is proposed that selectively converts Gaussian errors into Student's t errors according to latent outlier indicators, leveraging the best of the Gaussian and Student’s t errors; a parameter estimation can be not only robust but also accurate. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 15, 2019

2019 review

A Review and Tutorial of Machine Learning Methods for Microbiome Host Trait Prediction

[Review of ]. FRONTIERS IN GENETICS, 10.

By: Y. Zhou n & P. Gallins n

author keywords: disease; phenotype; modeling; machine learning; prediction
TL;DR: The most commonly used machine learning methods are explored, and their prediction accuracy as applied to microbiome host trait prediction is evaluated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 15, 2019

2019 journal article

Cheminformatics approach to exploring and modeling trait-associated metabolite profiles

JOURNAL OF CHEMINFORMATICS, 11.

author keywords: Metabolomics; Data mining; Cheminformatics; Molecular fragmentation; Statistics; Visualization; Chemical structure
TL;DR: A novel cheminformatics-based approach capable of identifying predictive, interpretable, and reproducible trait-metabolite relationships that could ultimately facilitate biological understanding and advance research based on metabolomics data, especially with respect to the identification of novel biomarkers. (via Semantic Scholar)
Source: Web Of Science
Added: July 15, 2019

2019 journal article

Asymptotic analysis of non-periodical cointegration with high seasonals

BOLETIN DE LA SOCIEDAD MATEMATICA MEXICANA, 25(2), 443–459.

author keywords: Cointegration; Asymptotic approximation; Periodicity; Nonstationarity
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 8, 2019

2019 journal article

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

NATURE COMMUNICATIONS, 10.

By: M. Menden*, D. Wang*, M. Mason*, B. Szalai*, K. Bulusu*, Y. Guan*, T. Yu*, J. Kang* ...

MeSH headings : ADAM17 Protein / antagonists & inhibitors; Antineoplastic Combined Chemotherapy Protocols / pharmacology; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Benchmarking; Biomarkers, Tumor / genetics; Cell Line, Tumor; Computational Biology / methods; Computational Biology / standards; Datasets as Topic; Drug Antagonism; Drug Resistance, Neoplasm / drug effects; Drug Resistance, Neoplasm / genetics; Drug Synergism; Genomics / methods; Humans; Molecular Targeted Therapy / methods; Mutation; Neoplasms / drug therapy; Neoplasms / genetics; Pharmacogenetics / methods; Pharmacogenetics / standards; Phosphatidylinositol 3-Kinases / genetics; Phosphoinositide-3 Kinase Inhibitors; Treatment Outcome
TL;DR: A large drug combination screen across cancer cell lines is provided to benchmark crowdsourced methods and to computationally predict drug synergies, and genomic rationale for synergy predictions are identified. (via Semantic Scholar)
Source: Web Of Science
Added: July 1, 2019

2019 journal article

FSEM: Functional Structural Equation Models for Twin Functional Data

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 114(525), 344–357.

author keywords: Covariance function; Genetic and environmental effects; Weighted likelihood ratio test
TL;DR: A novel class of functional structural equation models (FSEMs) for dissecting functional genetic and environmental effects on twin functional data, while characterizing the varying association between functional data and covariates of interest are developed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019

2019 journal article

COMPLETE SPATIAL MODEL CALIBRATION

ANNALS OF APPLIED STATISTICS, 13(2), 746–766.

By: Y. Huang, B. Reich*, M. Fuentes* & A. Sankarasubramanian

author keywords: Bayesian methods; calibration; spatial statistics
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019

2019 article

Discussion of "Penalized Spline of Propensity Methods for Treatment Comparison" by Zhou, Elliott, and Little

Yang, S., & Zeng, D. (2019, January 2). JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, Vol. 114, pp. 31–32.

By: S. Yang n & D. Zeng*

TL;DR: The article proposes a novel estimation of the average causal effects of the treatment strategies in the presence of timedependent confounding by indication, and extends the penalized spline of propensity methods in handling missing data to causal inference incorporating a temporal element into consideration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2019

2019 journal article

Bayesian mode and maximum estimation and accelerated rates of contraction

BERNOULLI, 25(3), 2330–2358.

By: W. Yoo* & S. Ghosal n

author keywords: anisotropic Holder space; credible set; maximum value; mode; nonparametric regression; posterior contraction; sequential; tensor-product B-splines; two-stage
TL;DR: This work proposes a Bayesian two-stage estimation procedure, where a second stage posterior is built based on samples collected within a credible set constructed from a first stage posterior, and can accelerate optimal contraction rates from the fixed-in-advanced setting to the minimax sequential rates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 1, 2019

2019 journal article

Empirical Likelihood for a Long Range Dependent Process Subordinated to a Gaussian Process

JOURNAL OF TIME SERIES ANALYSIS, 40(4), 447–466.

By: S. Lahiri n, U. Das* & D. Nordman*

author keywords: Geweke-Porter-Hudak estimator; long memory; M-estimators; non-central limit theorems; Wiener-Ito integrals
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: July 1, 2019

2019 journal article

The role of cellular contact and TGF-beta signaling in the activation of the epithelial mesenchymal transition (EMT)

CELL ADHESION & MIGRATION, 13(1), 63–75.

By: K. Gasior n, N. Wagner n, J. Cores n, R. Caspar n, A. Wilson n, S. Bhattacharya*, M. Hauck n

author keywords: EMT; TGF-; cellular adhesion; epithelial; mesenchymal; breast carcinoma; colon carcinoma
MeSH headings : Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Cell Adhesion; Cell Movement; Colorectal Neoplasms / metabolism; Colorectal Neoplasms / pathology; Epithelial-Mesenchymal Transition / drug effects; Female; Humans; Signal Transduction; Transforming Growth Factor beta / pharmacology; Tumor Cells, Cultured
TL;DR: Examination of the dual influence of the TGF-β pathway and intercellular contact on the activation of EMT in colon (SW480) and breast (MCF7) carcinoma cells highlights that, while EMT is induced by the synergy of multiple signals, this activation varies across cell types. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 24, 2019

2019 article

Interdisciplinarity of Ph.D. students across the Atlantic. A Case of Interdisciplinary Research Team Building at the Student Level

DESIGN JOURNAL, Vol. 22, pp. 1453–1466.

By: J. Park n, B. Kim n, B. Lee*, D. Hands* & T. Rider n

Source: Web Of Science
Added: June 24, 2019

2019 journal article

Minimal auxiliary Markov chains through sequential elimination of states

COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION, 48(4), 1040–1054.

By: D. Martin n

author keywords: completion strings; failure states; Markov chain embedding; minimal deterministic finite automaton; spaced seed coverage; structured motifs
TL;DR: A characterization of equivalent states is given so that extraneous states are deleted during the process of forming the state space, improving computational efficiency. (via Semantic Scholar)
Source: Web Of Science
Added: June 24, 2019

2019 journal article

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse

CHEMICAL RESEARCH IN TOXICOLOGY, 32(5), 887–898.

By: L. Lewis*, B. Borowa-Mazgaj*, A. Conti*, G. Chappell*, Y. Luo*, W. Bodnar*, K. Konganti*, F. Wright n ...

MeSH headings : Animals; Butadienes / toxicity; Carcinogens, Environmental / toxicity; DNA Adducts / chemistry; DNA Adducts / genetics; DNA Adducts / metabolism; DNA Methylation / drug effects; Epigenesis, Genetic / drug effects; Guanine / analogs & derivatives; Guanine / chemistry; Histones / metabolism; Kidney / drug effects; Liver / drug effects; Lung / drug effects; Male; Mice; Mutagens / toxicity
TL;DR: 1,3-butadiene is used to demonstrate how the Collaborative Cross mouse population can be used to identify the mechanisms for and quantify the degree of interindividual variability in tissue-specific effects that are relevant to chemically induced carcinogenesis. (via Semantic Scholar)
Source: Web Of Science
Added: June 17, 2019

2019 journal article

PERTURBATION BOOTSTRAP IN ADAPTIVE LASSO

ANNALS OF STATISTICS, 47(4), 2080–2116.

By: D. Das n, K. Gregory n & S. Lahiri n

author keywords: Alasso; naive perturbation bootstrap; modified perturbation bootstrap; second-order correctness; oracle
TL;DR: A modification to the perturbation bootstrap objective function is proposed and it is shown that a suitably studentized version of the modified perturbations bootstrap Alasso estimator achieves second-order correctness even when the dimension of the model is allowed to grow to infinity with the sample size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 17, 2019

2019 journal article

On an algorithm for solving Fredholm integrals of the first kind

STATISTICS AND COMPUTING, 29(4), 645–654.

author keywords: Brownian motion first passage time; Convergence; Expectation-maximization; Iterative algorithm; Mixture model
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 17, 2019

2019 journal article

Determining Normal Precipitation Ranges for Hydric Soil Assessments

SOIL SCIENCE SOCIETY OF AMERICA JOURNAL, 83(2), 503–510.

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 17, 2019

2019 review

Application of a sequential multiple assignment randomized trial (SMART) design in older patients with chronic lymphocytic leukemia

[Review of ]. ANNALS OF ONCOLOGY, 30(4), 542–550.

By: A. Ruppert*, J. Yin, M. Davidian n, A. Tsiatis n, J. Byrd*, J. Woyach*, S. Mandrekar

author keywords: SMART; CLL; design strategies; adaptive interventions; randomized clinical trials
MeSH headings : Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols / therapeutic use; Data Analysis; Disease Progression; Feasibility Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy; Leukemia, Lymphocytic, Chronic, B-Cell / mortality; Progression-Free Survival; Randomized Controlled Trials as Topic; Research Design; Sample Size
TL;DR: SMART design strategies can be used in cancer clinical trials with adaptive interventions to identify optimal treatment strategies and are appropriate when comparing adaptive interventions, which are defined by an individual's sequence of treatment decisions and guided by intermediate outcomes. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019

2019 journal article

Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with Bisphenol A and S

TOXICOLOGY, 420, 66–72.

author keywords: Bisphenol; Metabolism; Fat; BPF; Alternatives to BPA; Diabetes
MeSH headings : 3T3-L1 Cells; Adipocytes / drug effects; Adipocytes / metabolism; Adipogenesis / drug effects; Adipogenesis / genetics; Animals; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Phenols / toxicity; Sulfones / toxicity; Time Factors; Weight Gain / drug effects
TL;DR: The results suggest that BPS has a strong potential to be obesogenic while effects of BPF are subtler and potentially in the opposite direction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 17, 2019

2019 journal article

ON TESTING CONDITIONAL QUALITATIVE TREATMENT EFFECTS

ANNALS OF STATISTICS, 47(4), 2348–2377.

By: C. Shi n, R. Song n & W. Lu n

TL;DR: The proposed definition of CQTE does not assume any parametric form for the optimal treatment rule and plays an important role for assessing the incremental value of a set of new variables in optimal treatment decision making conditional on an existing set of prescriptive variables. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 17, 2019

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