Works Published in 2009
Displaying works 21 - 40 of 165 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Disruption of the Arsenic (+3 Oxidation State) Methyltransferase Gene in the Mouse Alters the Phenotype for Methylation of Arsenic and Affects Distribution and Retention of Orally Administered Arsenate
Chemical Research in Toxicology, 22(10), 1713–1720.
MeSH headings : Administration, Oral; Animals; Arsenates / administration & dosage; Arsenates / pharmacokinetics; Arsenates / urine; Arsenic Poisoning; Arsenicals / metabolism; Arsenicals / urine; Female; Genotype; Humans; Male; Methyltransferases / genetics; Methyltransferases / metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Tissue Distribution
TL;DR:
A central role for As3mt in the metabolism of inorganic arsenic is confirmed and phenotypes for arsenic retention and distribution are markedly affected by the null genotype for arsenic methylation, indicating a close linkage between the metabolism and retention of arsenicals.
(via Semantic Scholar)
europepmc.org (repository)
Source: Crossref
Added: January 21, 2021
2009 journal article
Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions
Toxicology and Applied Pharmacology, 239(2), 200–207.
author keywords: Arsenic-skin lesion; AS3MT polymorphism; Arsenic metabolism
MeSH headings : Adolescent; Adult; Arsenic / toxicity; Arsenic / urine; Case-Control Studies; Cross-Sectional Studies; DNA / genetics; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Gene Frequency; Genotype; Humans; Male; Methyltransferases / genetics; Mexico / epidemiology; Middle Aged; Mouth Mucosa / cytology; Polymorphism, Single Nucleotide; Precancerous Conditions / chemically induced; Precancerous Conditions / enzymology; Precancerous Conditions / epidemiology; Precancerous Conditions / genetics; Skin Neoplasms / chemically induced; Skin Neoplasms / enzymology; Skin Neoplasms / epidemiology; Skin Neoplasms / genetics; Water Pollutants, Chemical / toxicity; Water Pollutants, Chemical / urine; Young Adult
TL;DR:
Findings indicate that Met287Thr influences the susceptibility to premalignant As skin lesions and might be at increased risk for other adverse health effects of iAs exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Crossref
Added: January 21, 2021
2009 journal article
Metabolism of arsenic in human liver: the role of membrane transporters
Archives of Toxicology, 84(1), 3–16.
author keywords: Arsenic; Human liver; Membrane transport
MeSH headings : Aged; Aged, 80 and over; Animals; Arsenic / metabolism; Cell Membrane / metabolism; Cells, Cultured; Female; Glucose Transporter Type 2 / metabolism; Humans; Liver / metabolism; Male; Membrane Transport Proteins / metabolism; Methylation; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins / metabolism
TL;DR:
The results show that the retention of iAs and methylarsenic metabolites (MAs) by hepatocytes exposed to sub-micromolar concentrations of arsenite correlates negatively with MRP2 expression, and suggest that MRP 2 plays an important role in the efflux of DMAs, thus, regulating kinetics of the methylation reactions and accumulation of i as and MAs by human hepatocytes.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2009 chapter
Sources of Measurement Error, Misclassification Error, and Bias in Auditory Avian Point Count Data
In Modeling Demographic Processes In Marked Populations (pp. 237–254).
TL;DR:
The objectives are to: identify the factors that influence detection probability on auditory point counts, quantify the bias and precision of current sampling methods, and find new applications of sampling theory and methodologies that produce practical improvements in the quality of bird census data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
14. Life Below Water
(Web of Science)
15. Life on Land
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: September 15, 2020
2009 journal article
Occupational Risk Factors for Rhinitis Among Farmers in the Agricultural Health Study
Journal of Allergy and Clinical Immunology, 123(2), S266–S266.
TL;DR:
Handling hays and grains as well as farm maintenance activities may increase the risk of rhinitis in farmers.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2009 journal article
Cancer Incidence Among Pesticide Applicators Exposed to Methyl Bromide in the AHS
Annals of Epidemiology, 19(9), 662–663.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2009 journal article
Proceedings of the First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES-2007)
BMC Proceedings, 3(S2).
TL;DR:
A collection of articles as proceedings of the conference and an in-depth topical review of the utility of bioinformatics in the fields of toxicogenomics and environmental genomics are compiled.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2009 journal article
Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 20(2), 119–134.
author keywords: 2,4-D; chlorpyrifos; exposure measurement; farm applicator; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Humans; Skin / chemistry
Sources: Crossref, NC State University Libraries
Added: September 2, 2020
2009 journal article
Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage
Journal of Exposure Science & Environmental Epidemiology, 20(2), 169–175.
author keywords: biomarker; phthalate; reproducibility; menstrual cycle; temporal variability
MeSH headings : Cryopreservation; Female; Freezing; Humans; Menstrual Cycle; Phthalic Acids / urine; Reference Standards; Reproducibility of Results
TL;DR:
Results suggest that the measurement of phthalate metabolites after long-term sample storage yield generally similar distributions and temporal reliability as those reported for recently collected specimens, and support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence ofphthalate exposures on later outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020
2009 journal article
Assessment of a pesticide exposure intensity algorithm in the agricultural health study
Journal of Exposure Science & Environmental Epidemiology, 20(6), 559–569.
author keywords: 2,4-D; chlorpyrifos; exposure measurement; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Agriculture; Air Pollutants, Occupational / analysis; Air Pollutants, Occupational / urine; Algorithms; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Cohort Studies; Environmental Exposure / analysis; Environmental Monitoring / methods; Gas Chromatography-Mass Spectrometry; Humans; Iowa; Linear Models; North Carolina; Occupational Exposure / analysis; Pesticides / analysis; Pesticides / urine; Risk Assessment / methods; Skin Absorption; Surveys and Questionnaires
TL;DR:
The results of the measurements support the use of the algorithm for estimating questionnaire-based exposure intensities in the AHS for liquid pesticide products and refine the algorithm may be possible using the results from this and other measurement studies.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020
2009 journal article
Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice
Hormones and Behavior, 56(2), 254–263.
author keywords: Male copulatory behavior; Sexual behavior; Partner preference; B6D2F1 hybrid mice; Libido; Androgen receptors; Aromatase; Estrogen receptors
MeSH headings : Androgen Antagonists / pharmacology; Androgen Receptor Antagonists; Androgens / metabolism; Animals; Aromatase / metabolism; Aromatase Inhibitors / pharmacology; Copulation / drug effects; Copulation / physiology; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Estrogen Receptor alpha / antagonists & inhibitors; Estrogen Receptor alpha / metabolism; Estrogens / metabolism; Female; Flutamide / pharmacology; Fulvestrant; Letrozole; Male; Mating Preference, Animal / drug effects; Mating Preference, Animal / physiology; Mice; Nitriles / pharmacology; Orchiectomy; Preoptic Area / drug effects; Preoptic Area / physiology; RNA, Messenger / metabolism; Receptors, Androgen / metabolism; Septal Nuclei / drug effects; Septal Nuclei / physiology; Triazoles / pharmacology
TL;DR:
It is suggested that non-gonadal androgens and estrogens do not maintainCopulatory behavior in B6D2F1 mice which display copulatory behavior after castration, and this preference persisted after long-term castration in persistent copulators.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Regulation of progestin receptors in medial amygdala: Estradiol, phytoestrogens and sex
Physiology & Behavior, 97(2), 146–150.
author keywords: Phytoestrogens; Environmental estrogens; Endocrine disrupting compounds; Progestin receptor; Medial amygdala; Sex differences; Sexual differentiation; Soy
MeSH headings : Amygdala / cytology; Amygdala / metabolism; Analysis of Variance; Animals; Aromatase / deficiency; Castration / methods; Cell Count / methods; Estradiol / pharmacology; Estrogens / pharmacology; Female; Gene Expression Regulation / drug effects; Gene Expression Regulation / genetics; Gene Expression Regulation / physiology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons / drug effects; Neurons / metabolism; Phytoestrogens / pharmacology; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism
TL;DR:
It is hypothesized that both aromatization of androgens to estrogens and dietary sources of additional estrogens are part of the normal requirement for sex differences in the rodent brain.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Irc15 Is a Microtubule-Associated Protein that Regulates Microtubule Dynamics in Saccharomyces cerevisiae
Current Biology, 19(6), 472–478.
MeSH headings : Chromosomes, Fungal / genetics; Conserved Sequence; Cytoplasm / physiology; Dihydrolipoamide Dehydrogenase / genetics; Genes, Reporter; Glycolysis; Homeostasis; Microtubule-Associated Proteins / genetics; Microtubule-Associated Proteins / physiology; Microtubules / physiology; Microtubules / ultrastructure; Mutation; Saccharomyces cerevisiae / cytology; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / physiology; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / physiology; Stress, Mechanical
TL;DR:
Evidence is presented that Irc15 regulates microtubule dynamics in vivo and loss of IRC15 function leads to delayed mitotic progression, resulting from failure to establish tension between sister kinetochores.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
Identification of chromosome 7 inversion breakpoints in an autistic family narrows candidate region for autism susceptibility
Autism Research, 2(5), 258–266.
author keywords: molecular genetics; paracentric inversion; fluorescent in situ hybridization (FISH); genome-wide association study (GWAS)
MeSH headings : Autistic Disorder / genetics; Child; Child, Preschool; Chromosome Inversion / genetics; Chromosomes, Human, Pair 7 / genetics; Comparative Genomic Hybridization / methods; DNA Copy Number Variations / genetics; Family; Female; Follow-Up Studies; Genetic Markers / genetics; Genetic Predisposition to Disease / genetics; Humans; In Situ Hybridization, Fluorescence / methods; Male; Oligonucleotide Array Sequence Analysis / methods; Polymorphism, Single Nucleotide / genetics
TL;DR:
The chromosomal abnormality in this family strengthens the case for an autism susceptibility gene in the chromosome 7q22‐31 region and targets a candidate region for further investigation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Predictors of Variation in Serum IGFI and IGFBP3 Levels in Healthy African American and White Men
Journal of the National Medical Association, 101(7), 711–716.
author keywords: insulin; race/ethnicity
MeSH headings : Adult; Black or African American / statistics & numerical data; Alleles; Body Mass Index; Genetic Variation; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Proteins / genetics; Insulin-Like Growth Factor Binding Proteins / metabolism; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Life Style; Linear Models; Male; Predictive Value of Tests; Promoter Regions, Genetic; Smoking / epidemiology; Socioeconomic Factors; United States / epidemiology; White People / statistics & numerical data
TL;DR:
If successfully replicated in larger studies, these findings would add to recent evidence, suggesting known genetic and lifestyle chronic disease risk factors influence IGF1 and IGFBP3 circulating levels differently in African Americans and whites.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Exercise and Prostate Cancer Risk in a Cohort of Veterans Undergoing Prostate Needle Biopsy
Journal of Urology, 182(5), 2226–2231.
author keywords: prostatic neoplasms; exercise; risk factors
MeSH headings : Aged; Biopsy, Needle; Exercise; Humans; Male; Middle Aged; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / pathology; Prostatic Neoplasms / prevention & control; Risk Factors
TL;DR:
Moderate exercise was associated with a lower risk of prostate cancer and in men with cancer, lower grade disease, the first evidence of an association between exercise and prostate cancer risk as well as grade at diagnosis in men scheduled to undergo prostate biopsy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
70: Epigenetic orchestration of circulating insulin-like growth factor-2 levels in cord blood
American Journal of Obstetrics and Gynecology, 201(6), S39.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2009 journal article
Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster
Genetics Research, 91(6), 373–382.
MeSH headings : Animals; Drosophila melanogaster / genetics; Epistasis, Genetic; Genome, Insect; Mutation; Phenotype; Quantitative Trait Loci; Reflex, Startle / genetics; Selection, Genetic
TL;DR:
A partial glimpse of the complex genetic network underlying the genetic architecture of startle behaviour is provided and empirical support is provided for the hypothesis that suppressing epistasis is the mechanism underlying genetic canalization of traits under strong stabilizing selection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Crossref
Added: August 28, 2020
2009 journal article
Understanding the neurogenetics of sleep: progress from Drosophila
Trends in Genetics, 25(6), 262–269.
MeSH headings : Animals; Drosophila / genetics; Drosophila / metabolism; Sleep / genetics; Sleep / physiology
TL;DR:
Drosophila melanogaster exhibits all the behavioral characteristics of mammalian sleep, enabling the use of powerful genetic approaches to dissect conserved fundamental neurogenetic aspects of sleep.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 24, 2020
2009 journal article
Time course of changes in Gambel's white-crowned sparrow song behavior following transitions in breeding condition
Hormones and Behavior, 55(1), 217–227.
author keywords: Gambel's white-crowned sparrow; Zonotrichia leucophrys gambelii; Testosterone; Birdsong; Songbird; Seasonal plasticity; Photoperiod
MeSH headings : Analysis of Variance; Animals; Cues; Male; Photoperiod; Radioimmunoassay; Seasons; Sexual Behavior, Animal / drug effects; Sparrows / physiology; Stereotyped Behavior / drug effects; Testosterone / administration & dosage; Testosterone / blood; Vocalization, Animal / drug effects
TL;DR:
It is suggested that while song rate changes quickly, song phonology changes more slowly, generally following or in parallel with previously investigated changes in the neural substrate.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
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