Works Published in 2020
Displaying works 21 - 32 of 32 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 review
The Use and Misuse of Historical Controls in Regulatory Toxicology: Lessons from the CLARITY-BPA Study
[Review of ]. ENDOCRINOLOGY, 161(5).
author keywords: adenocarcinoma; Food and Drug Administration; gavage; lymphocyte infiltration; National Toxicology Program; obesity
MeSH headings : Animals; Benzhydryl Compounds / poisoning; Benzhydryl Compounds / toxicity; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / poisoning; Endocrine Disruptors / toxicity; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Guidelines as Topic; Humans; National Institute of Environmental Health Sciences (U.S.); Phenols / poisoning; Phenols / toxicity; Toxicity Tests / methods; Toxicity Tests / standards; United States; United States Food and Drug Administration
TL;DR:
Using FDA-proposed historical control data, an aspect of "guideline" studies, the use of so-called "historical controls", which are essentially control data borrowed from prior studies to aid in the interpretation of current findings are examined.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020
2020 journal article
Analysis of neurotransmitters in rat placenta exposed to flame retardants using IR-MALDESI mass spectrometry imaging
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(15), 3745–3752.
author keywords: IR-MALDESI; Mass spectrometry imaging; Neurotransmitters; Exposomics
MeSH headings : Animals; Female; Flame Retardants / adverse effects; Infrared Rays; Neurotransmitter Agents / analysis; Optical Imaging / instrumentation; Optical Imaging / methods; Placenta / chemistry; Placenta / diagnostic imaging; Pregnancy; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR:
Changes in the abundance and spatial distribution of neurotransmitters in rat placenta following chemical exposure could be determined using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) mass spectrometry imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020
2020 journal article
The basic reproductive number for disease systems with multiple coupled heterogeneities
Mathematical Biosciences.
author keywords: Disease transmission model; Heterogeneity; Basic reproductive number; Coupled heterogeneities
MeSH headings : Basic Reproduction Number; Humans; Models, Biological
doi.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: May 14, 2020
2020 article
Bidirectional contact tracing dramatically improves COVID-19 control
Bradshaw, W. J., Alley, E. C., Huggins, J. H., Lloyd, A. L., & Esvelt, K. M. (2020, May 10). (Vol. 5). Vol. 5.
TL;DR:
It is shown that “bidirectional” tracing to identify infector individuals and their other infectees robustly improves outbreak control, reducing the effective reproduction number (Reff) by at least ∼0.3 while dramatically increasing resilience to low case ascertainment and test sensitivity.
(via Semantic Scholar)
Source: ORCID
Added: May 11, 2020
2020 journal article
Chimera: A Massively Parallel Code for Core-collapse Supernova Simulations
The Astrophysical Journal Supplement Series.
author keywords: Core-collapse supernovae; Computational methods; Reaction rates; Radiative transfer simulations; Supernova neutrinos; Hydrodynamical simulations; Nucleosynthesis
TL;DR:
The Chimera code, a code developed to model core collapse supernovae (CCSNe) in multiple spatial dimensions, is detail here the current version of the code, from which future improvements will stem, which can be described as needed in future publications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
Source: ORCID
Added: May 1, 2020
2020 journal article
Optimizing the deployment of ultra-low volume and targeted indoor residual spraying for dengue outbreak response
PLOS Computational Biology, 16(4), e1007743.
Ed(s): M. Pascual
MeSH headings : Aedes / physiology; Animals; Computational Biology / methods; Computer Simulation; Dengue / epidemiology; Dengue / prevention & control; Dengue / transmission; Disease Outbreaks; Humans; Incidence; Insecticides; Models, Theoretical; Mosquito Control / methods; Mosquito Vectors; Zika Virus Infection / epidemiology; Zika Virus Infection / prevention & control; Zika Virus Infection / transmission
TL;DR:
Although spraying twice each year is likely to avert the most infections, the results indicate that a threshold-based strategy can become an alternative to better balance the translation of spraying effort into impact, particularly if used with a residual insecticide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: April 21, 2020
2020 journal article
Temporal and bidirectional influences of estradiol on voluntary wheel running in adult female and male rats
HORMONES AND BEHAVIOR, 120.
author keywords: Estradiol; Sex differences; Voluntary wheel running; Locomotion; Motivation
MeSH headings : Animals; Behavior, Animal / drug effects; Estradiol / analogs & derivatives; Estradiol / pharmacology; Female; Male; Motivation / drug effects; Motor Activity / drug effects; Rats; Rats, Sprague-Dawley; Running / physiology; Sex Characteristics; Time Factors
TL;DR:
Findings indicate that estradiol rapidly, non-rapidly, and bidirectionally modulates wheel running in a sex-responsive manner, and that rapid est radiol action is modulated by non-Rapid Estradiol action.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020
2020 journal article
Quaternary drainage network reorganization in the Colombian Eastern Cordillera plateau
EARTH SURFACE PROCESSES AND LANDFORMS, 45(8), 1789–1804.
author keywords: drainage evolution; fluvial capture; cosmogenic nuclides; chi analysis; Eastern Cordillera of Colombia
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: April 14, 2020
2020 journal article
Landslide development within 3 years after the 2015 M-w 7.8 Gorkha earthquake, Nepal
LANDSLIDES, 17(5), 1251–1267.
author keywords: 2015 Gorkha earthquake; Nepal; Himalaya; Landsliding; Ground-based investigation; UAV photography; Remote sensing
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: March 16, 2020
2020 review
Achieving CLARITY on bisphenol A, brain and behaviour
[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 32(1).
author keywords: amygdala; anxiety; EDC; endocrine disrupting chemical; hypothalamus; oxytocin
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Brain / drug effects; Endocrine Disruptors / toxicity; Female; Humans; Male; Neurons / drug effects; Phenols / toxicity; Pregnancy; Sex Differentiation / drug effects; United States; United States Food and Drug Administration
TL;DR:
Evidence of altered neuroendocrine development, including age‐ and sex‐specific expression of oestrogen receptor (ER)α and ERβ, and the abrogation of brain and behavioural sexual dimorphisms, supports the conclusion that developmental BPA exposure, even at doses below what regulatory agencies regard as “safe” for humans, contribute to brain and behaviour change.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 17, 2020
2020 journal article
Metabotropic glutamate receptor subtype 5 (mGlu(5)) is necessary for estradiol mitigation of light-induced anxiety behavior in female rats
PHYSIOLOGY & BEHAVIOR, 214.
author keywords: Estradiol; Metabotropic glutamate receptor 5; Female; Anxiety; Estrogen
MeSH headings : Animals; Anxiety / prevention & control; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Excitatory Amino Acid Antagonists / pharmacology; Female; Light; Locomotion / drug effects; Ovariectomy; Pyridines / pharmacology; Rats; Receptor, Metabotropic Glutamate 5 / metabolism
TL;DR:
Novel findings indicate that mGlu5 activation is necessary for estradiol mitigation of anxiety-related behaviors induced by an acute stressor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 10, 2020
2020 journal article
Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification
NATURE REVIEWS ENDOCRINOLOGY, 16(1), 45–57.
MeSH headings : Animals; Consensus; Endocrine Disruptors / adverse effects; Environmental Exposure / adverse effects; Environmental Exposure / prevention & control; Environmental Pollutants / adverse effects; Environmental Pollutants / metabolism; Humans; Receptors, Corticotropin / metabolism
TL;DR:
This Expert Consensus Statement reflects on how these ten KCs can be used to identify, organize and utilize mechanistic data when evaluating chemicals as EDCs, and uses diethylstilbestrol, bisphenol A and perchlorate as examples to illustrate this approach.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: December 30, 2019
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