Works Published in 2005
Displaying works 41 - 60 of 148 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Feasibility of using subject-collected dust samples in epidemiological and clinical studies of indoor allergens
Journal of Allergy and Clinical Immunology, 115(2), S97.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2005 journal article
Characteristics of the Structure of Minor Variants of External Transcribed Spacers of Ribosomal DNA of the Cockroach Blattella germanica
Doklady Biological Sciences, 404(1-6), 348–351.
MeSH headings : Animals; Base Sequence; Blattellidae / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; Molecular Sequence Data; Transcription, Genetic
TL;DR:
The suggested models con-ceptually agree with the postulates of thegenetic monomorphism theory, according to which theformation of a new species is regarded as the result of large-scale genetic reorganization marked by mono-morphic signs rather than a gradual probabilistic pro-cess taking place at the population level.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2005 journal article
Discovery of retrotransposons of the cockroach Blattella germanica
Doklady Biochemistry and Biophysics, 401(1-6), 104–107.
MeSH headings : Amino Acid Sequence; Animals; Blattellidae / genetics; Molecular Sequence Data; Open Reading Frames / genetics; Retroelements / genetics
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2005 journal article
Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism
Proceedings of the National Academy of Sciences, 102(42), 15018–15023.
author keywords: disulfide; flavoprotein; selenocysteine; selenoprotein
MeSH headings : Animals; Binding Sites; Crystallography, X-Ray; Homeostasis; Isoenzymes / chemistry; Isoenzymes / metabolism; Mice; Mitochondria / enzymology; Models, Molecular; NADP / metabolism; Oxidation-Reduction; Protein Structure, Quaternary; Protein Subunits / chemistry; Protein Subunits / metabolism; Thioredoxin Reductase 2; Thioredoxin-Disulfide Reductase / chemistry; Thioredoxin-Disulfide Reductase / metabolism
TL;DR:
Detailed analysis of the structural data in conjunction with a model of the unusual C-terminal selenenylsulfide suggests molecular details of the reaction mechanism and highlights evolutionary adaptations among reductases.
(via Semantic Scholar)
www.pnas.org (publisher PDF)
Source: Crossref
Added: August 28, 2020
2005 journal article
Tertiary amide chemistry at the Ge(100)-2×1 surface
Surface Science, 599(1-3), 41–54.
author keywords: density functional calculations; vibrational spectroscopies; germanium; organic molecules; organo-functionalization of surfaces; desorption; amide; Ge(100)
Source: Crossref
Added: August 28, 2020
2005 journal article
A previously uncharacterized role for estrogen receptor : Defeminization of male brain and behavior
Proceedings of the National Academy of Sciences, 102(12), 4608–4612.
author keywords: developmental neurobiology; neuroendocrinology; sexual differentiation
MeSH headings : Animals; Brain / physiology; Estrogen Receptor beta / deficiency; Estrogen Receptor beta / genetics; Estrogen Receptor beta / physiology; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Neurological; Orchiectomy; Sex Characteristics; Sexual Behavior, Animal / physiology; Smell / physiology; Testis / physiology
TL;DR:
It is hypothesized that ERbeta is involved in defeminization of brain and behavior, and this aspect of ERbeta function may lead to developments in the understanding of neural-based sexually dimorphic human behaviors.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Effects of galanin-like peptide (GALP) on locomotion, reproduction, and body weight in female and male mice
Hormones and Behavior, 48(2), 141–151.
author keywords: sexual behavior; energy balance; motor control; coordination; exploration; luteinizing hormone; gonadotropin-releasing hormone
MeSH headings : Animals; Body Weight / drug effects; Energy Metabolism / drug effects; Female; Galanin-Like Peptide / pharmacology; Gonadotropin-Releasing Hormone / physiology; Injections, Intraventricular; Luteinizing Hormone / blood; Male; Mice; Mice, Inbred C57BL; Motor Activity / drug effects; Ovariectomy; Postural Balance / drug effects; Reproduction / drug effects; Sexual Behavior, Animal / drug effects; Stereotaxic Techniques
TL;DR:
Data indicate that in female mice, GALP stimulates LH release via GnRH, and decreases body weight, motor control, and locomotor activity via Gn RH-independent pathways, and species-specific differences in the mechanism and/or location of GALp action in the brains of rats and mice are suggested.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Lack of functional estrogen receptor β influences anxiety behavior and serotonin content in female mice
Physiology & Behavior, 84(1), 157–163.
author keywords: SSRI; menopause; estrogen receptor; depression; anxiety; serotonin
MeSH headings : Analysis of Variance; Animals; Anxiety / genetics; Anxiety / metabolism; Anxiety / physiopathology; Behavior, Animal; Biogenic Monoamines / metabolism; Brain Chemistry / drug effects; Brain Chemistry / genetics; Chromatography, High Pressure Liquid / methods; Estradiol / pharmacology; Estrogen Receptor beta / deficiency; Estrogen Receptor beta / genetics; Exploratory Behavior / drug effects; Female; Genotype; Maze Learning / drug effects; Mice; Mice, Knockout; Ovariectomy / methods; Serotonin / metabolism; Time Factors
TL;DR:
It is hypothesized that ERbeta is required during development to modulate the effects of estrogen on anxiety and catecholamine concentrations in female mouse brains in the absence of functional ERbeta.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Dopamine D5 receptor modulates male and female sexual behavior in mice
Psychopharmacology, 180(2), 206–214.
author keywords: sexual behavior; dopamine; conditioned place preference; drugs; motivation; knockout mice; reward; attention deficit hyperactivity disorder
MeSH headings : Animals; Apomorphine / pharmacology; Conditioning, Psychological; Estradiol / pharmacology; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Progesterone / pharmacology; Reward; Sexual Behavior, Animal
TL;DR:
The work suggests that the D5 receptor mediates dopamine’s action on sexual behavior in both sexes, perhaps via a reward pathway.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Pain predicts non-adherence to pap smear screening among middle-aged African American women
Preventive Medicine, 41(2), 439–445.
author keywords: cervix neoplasms; screening; pap tests; African Americans; middle-aged; barriers; pain
MeSH headings : Black or African American / statistics & numerical data; Aged; Cross-Sectional Studies; Female; Focus Groups; Humans; Logistic Models; Middle Aged; Pain / etiology; Papanicolaou Test; Patient Acceptance of Health Care; United States; Uterine Cervical Neoplasms / prevention & control; Vaginal Smears / adverse effects; Vaginal Smears / statistics & numerical data
TL;DR:
Data suggest that, among middle-aged African American women, future interventions addressing pain during a Pap test will likely increase acceptability of and adherence to cervical cancer screening.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Anthropometric Measurements and Epithelial Ovarian Cancer Risk in African–American and White women
Cancer Causes & Control, 16(8), 955–963.
author keywords: body height; body mass index; etiology; ovarian neoplasms
MeSH headings : Adult; Black or African American / classification; Aged; Anthropometry; Body Height; Body Mass Index; Case-Control Studies; Confounding Factors, Epidemiologic; Female; Humans; Middle Aged; North Carolina / ethnology; Odds Ratio; Ovarian Neoplasms / ethnology; Risk Factors; White People / classification
TL;DR:
The hypothesis that obesity is an important risk factor of ovarian cancer among African–Americans and Whites is supported and height may be a risk factor specific to African–American women is suggested.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Genetic Modifiers of Lung Disease in Cystic Fibrosis
New England Journal of Medicine, 353(14), 1443–1453.
MeSH headings : Adolescent; Adult; Child; Cystic Fibrosis / classification; Cystic Fibrosis / genetics; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; DNA Replication; Female; Forced Expiratory Volume; Genotype; Humans; Linkage Disequilibrium; Logistic Models; Lung Diseases / classification; Lung Diseases / genetics; Lung Diseases / physiopathology; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Severity of Illness Index; Transforming Growth Factor beta / genetics
TL;DR:
Genetic variation in the 5' end of TGFbeta1 or a nearby upstream region modifies disease severity in cystic fibrosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Group A Streptococcus Transcriptome Dynamics during Growth in Human Blood Reveals Bacterial Adaptive and Survival Strategies
The American Journal of Pathology, 166(2), 455–465.
MeSH headings : DNA, Complementary / metabolism; Female; Flow Cytometry; Gene Expression Regulation, Bacterial; Humans; Male; Models, Biological; Mutation; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; RNA / metabolism; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections / blood; Streptococcal Infections / metabolism; Streptococcus / metabolism; Time Factors
TL;DR:
Investigation of the transcriptome of a wild-type serotype M1 GAS strain in human blood reinforced the hypothesis that CovR-CovS has an important role linking key biosynthetic, catabolic, and virulence functions during transcriptome restructuring.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Mutations in Serac1 or Synj2 cause proximal t haplotype-mediated male mouse sterility but not transmission ratio distortion
Proceedings of the National Academy of Sciences, 102(9), 3342–3347.
Contributors: J. Schimenti *, J. Reynolds * & A. Planchart*
MeSH headings : Animals; Base Sequence; Chromosomes, Artificial, Bacterial; DNA; Haplotypes; Infertility, Male / genetics; Male; Mice; Molecular Sequence Data; Mutation; Nerve Tissue Proteins / genetics; Phosphoric Monoester Hydrolases / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
Results uncouple the proximal t haplotype sterility locus, S1, from TRD, demonstrating that S1 and the proximate distorter loci, D1, are not the same gene.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2005 journal article
Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?
Marine Pollution Bulletin, 51(8-12), 635–648.
MeSH headings : Animals; Animals, Genetically Modified / metabolism; Carcinogenicity Tests / methods; Ecology / methods; Endocrine Disruptors / metabolism; Environmental Pollutants / metabolism; Models, Animal; Oligonucleotide Array Sequence Analysis / methods; Toxicology / methods; Toxicology / trends
TL;DR:
Studies resolving mechanisms of toxicity are reviewed and ways to address biocomplexity, mixtures of contaminants, and the need to relate individual level responses to populations and communities are discussed.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Functional characterization of medaka CYP3A38 and CYP3A40: Kinetics and catalysis by expression in a recombinant baculovirus system
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 141(4), 338–348.
author keywords: medaka; CYP3A; baculovirus; cytochrome P450; kinetics; testosterone; BFC; metabolism
MeSH headings : Amino Acid Sequence; Animals; Baculoviridae / genetics; Catalysis; Cytochrome P-450 CYP3A / chemistry; Cytochrome P-450 CYP3A / metabolism; Kinetics; Molecular Sequence Data; Oryzias / metabolism; Oxazines / metabolism; Recombinant Proteins / metabolism; Testosterone / metabolism
TL;DR:
Describing the catalytic and kinetic activities of two medaka CYP3A paralogs with benzyloxyresorufin (BFC), a fluorescent 3A-selective substrate, and testosterone suggests that differences in kinetics and catalytic activities are a result of amino acid substitutions in SRS regions 1, 3 and 5 within the CYP1A38 and CYP2A40 protein sequence.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Differences in Dissolved Cadmium and Zinc Uptake among Stream Insects: Mechanistic Explanations
Environmental Science & Technology, 39(2), 498–504.
MeSH headings : Animals; Biological Availability; Cadmium / pharmacokinetics; Insecta; Kinetics; Solubility; Tissue Distribution; Water Pollutants / pharmacokinetics; Zinc / pharmacokinetics
TL;DR:
Comparing dissolved Cd and Zn uptake rates in several aquatic insect species demonstrated that species vary widely in these processes, suggesting that these metals are transported by similar mechanisms.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Mapping Sites of Protein Phosphorylation by Mass Spectrometry Utilizing a Chemical-Enzymatic Approach: Characterization of Products from α-S1Casein Phosphopeptides
Journal of Proteome Research, 4(2), 424–434.
author keywords: chemical-enzymatic; phosphorylation; 2-aminoethanethiol; isotope dilution mass spectrometry; phosphoproteins; phosphopeptides; quantification
MeSH headings : Amino Acid Sequence; Animals; Caseins / metabolism; Cattle; Molecular Sequence Data; Peptide Fragments / metabolism; Phosphopeptides / metabolism; Phosphorylation; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
ESI-TOF mass spectrometry was used to characterize products from the chemical-enzymatic cleavage of specific phosphorylation sites in bovine alpha-S1 casein and synthetic phosphopeptides containing substitutions at a single phosphorylated site.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Protein expression profiling of CLL B cells using replicate off-line strong cation exchange chromatography and LC–MS/MS
Journal of Chromatography B, 819(1), 33–39.
author keywords: CLL; 2D-LC-MS/MS; B cell; expression profiling; off-line SCX; reproducibility
MeSH headings : Antigens, CD / isolation & purification; B-Lymphocytes / metabolism; Blood Proteins / isolation & purification; Cell Fractionation; Cell Membrane / chemistry; Chromatography, Ion Exchange / methods; Chromatography, Liquid / methods; Gene Expression Profiling / methods; Humans; Leukemia, Lymphocytic, Chronic, B-Cell / metabolism; Mass Spectrometry / methods; Neoplasm Proteins / blood
TL;DR:
Examination of crude membranes from B cells derived from a patient with chronic lymphocytic leukemia to examine the protein expression profile of CLL B cells shows an overlap of 64% between proteins identified in replicate runs was achieved for this system.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2005 journal article
Déjà Vu All Over Again: Skin Cap Still Contains a High-Potency Glucocorticosteroid
Archives of Dermatology, 141(6).
MeSH headings : Administration, Topical; Adrenal Cortex Hormones / adverse effects; Adrenal Cortex Hormones / chemistry; Adrenal Cortex Hormones / therapeutic use; Chemistry, Pharmaceutical; Dermatologic Agents / adverse effects; Dermatologic Agents / pharmacology; Dermatologic Agents / therapeutic use; Female; Humans; Male; Materials Testing; Psoriasis / diagnosis; Psoriasis / drug therapy; Risk Assessment; Sensitivity and Specificity
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
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