Works Published in 2018
Displaying works 121 - 140 of 252 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Editorial overview: Omics
Current Opinion in Chemical Biology, 42, A1–A2.
Contributors: P. Barran* & E. Baker*
MeSH headings : Genomics / methods; Humans; Ion Mobility Spectrometry / methods; Lipid Metabolism; Mass Spectrometry / methods; Metabolomics / methods; Proteomics / methods
Source: ORCID
Added: December 5, 2019
2018 journal article
An algorithm to correct saturated mass spectrometry ion abundances for enhanced quantitation and mass accuracy in omic studies
International Journal of Mass Spectrometry, 427, 91–99.
Contributors: A. Bilbao *, B. Gibbons*, G. Slysz*, K. Crowell*, M. Monroe *, Y. Ibrahim *, R. Smith *, S. Payne *, E. Baker*
author keywords: Mass spectrometry; Detector saturation; Analog-to-digital converter saturation; Saturation correction; Isotopic envelope; Isotopic ratios; Quantitation
TL;DR:
The isotopic envelope for each observed ion above the saturation threshold is compared to its expected theoretical isotopic distribution and the most intense isotopic peak for which saturation does not occur is utilized to re-calculate the precursor m/z and correct the intensity, resulting in both higher mass accuracy and greater dynamic range.
(via Semantic Scholar)
europepmc.org (repository)
Source: ORCID
Added: December 5, 2019
2018 journal article
A Customizable Flow Injection System for Automated, High Throughput, and Time Sensitive Ion Mobility Spectrometry and Mass Spectrometry Measurements
Analytical Chemistry, 90(1), 737–744.
Contributors: D. Orton *, M. Tfaily *, R. Moore *, B. Lamarche*, X. Zheng *, T. Fillmore *, R. Chu*, K. Weitz *
MeSH headings : Escherichia coli / chemistry; Escherichia coli Proteins / chemistry; Flow Injection Analysis / instrumentation; Flow Injection Analysis / methods; Hydrogen-Ion Concentration; Ion Mobility Spectrometry / instrumentation; Ion Mobility Spectrometry / methods; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Soil / chemistry
TL;DR:
An automated, customizable FIA system capable of operating at a range of flow rates to accommodate both low- and high-flow MS ionization sources and showing a highly robust and reproducible platform capable of providing consistent performance over many days without carryover.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Guest editor's personal foreward
International Journal of Mass Spectrometry, 427, 1–3.
Contributors: E. Baker* & R. Ogorzalek Loo*
Source: ORCID
Added: December 5, 2019
2018 journal article
Distinguishing enantiomeric amino acids with chiral cyclodextrin adducts and structures for lossless ion manipulations
Electrophoresis, 39(24), 3148–3155.
Contributors: G. Nagy *, C. Chouinard *, I. Attah *, I. Webb *, S. Garimella *, Y. Ibrahim *, E. Baker* , R. Smith *
author keywords: Chiral separations; Cyclodextrins; Enantiomers; Ion mobility-mass spectrometry; Structures for lossless ion manipulations
MeSH headings : Amino Acids / analysis; Amino Acids / chemistry; Amino Acids / isolation & purification; Cyclodextrins / chemistry; Ions; Mass Spectrometry / methods; Models, Molecular; Stereoisomerism
TL;DR:
The SLIM was used to accumulate much larger ion populations than previously feasible for evaluation and therefore allow enantiomeric measurements of higher sensitivity, with gains in resolution from the ultralong path separation capabilities, than previously reported by any other IM–based approach.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey
PLoS ONE, 13(2).
Contributors: J. Horney *, G. Casillas *, E. Baker* , K. Stone *, K. Kirsch *, K. Camargo*, T. Wade *, T. McDonald *
MeSH headings : Cyclonic Storms; Environmental Pollutants / analysis; Gas Chromatography-Mass Spectrometry; Polycyclic Aromatic Hydrocarbons / analysis; Residence Characteristics; Texas
TL;DR:
A small longitudinal study to assess domestic exposure to PAHs among residents of Manchester, an environmental justice neighborhood located in the East End of Houston, TX, found evidence of redistribution ofPAHs due to extreme flooding associated with Hurricane Harvey.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Cell type-resolved human lung lipidome reveals cellular cooperation in lung function
Scientific Reports, 8(1).
Contributors: J. Kyle *, G. Clair *, G. Bandyopadhyay *, R. Misra *, E. Zink *, K. Bloodsworth *, A. Shukla *, Y. Du *
MeSH headings : Databases, Protein; Female; Humans; Lipid Metabolism / physiology; Lung / cytology; Lung / physiology; Male
TL;DR:
Lipidomics analyses showed significant variations in the lipidome across major human lung cell types, with differences most evident at the subclass and intra-subclass level, and lipidomic signatures revealed an overarching posture of high cellular cooperation within the human lung to support critical functions.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Application of multiplexed ion mobility spectrometry towards the identification of host protein signatures of treatment effect in pulmonary tuberculosis
Tuberculosis, 112, 52–61.
Contributors: K. Kedia *, J. Wendler*, E. Baker* , K. Burnum-Johnson *, L. Jarsberg*, K. Stratton *, A. Wright *, P. Piehowski *
author keywords: Ion mobility spectrometry; Proteomics; Tuberculosis; Antibiotic treatment
MeSH headings : Adolescent; Adult; Antitubercular Agents / therapeutic use; Biomarkers / blood; Blood Proteins / metabolism; Child; Child, Preschool; Chromatography, Liquid; Drug Therapy, Combination; Female; High-Throughput Screening Assays; Host-Pathogen Interactions; Humans; Infant; Infant, Newborn; Ion Mobility Spectrometry; Male; Mass Spectrometry; Middle Aged; North America; Predictive Value of Tests; Prospective Studies; Protein Interaction Maps; Proteomics / methods; South Africa; Spain; Time Factors; Treatment Outcome; Tuberculosis, Pulmonary / blood; Tuberculosis, Pulmonary / diagnosis; Tuberculosis, Pulmonary / drug therapy; Tuberculosis, Pulmonary / microbiology; Uganda; Young Adult
TL;DR:
If validated in cohorts with long term follow-up to capture failure and relapse of TB, these protein markers could be developed for monitoring of treatment in clinical trials and in patient care.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
Quantitative self-assembly prediction yields targeted nanomedicines
Nature Materials.
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Carriers / pharmacokinetics; Endocytosis; Indoles / chemistry; Mice; Nanomedicine / methods; Nanoparticles / chemistry; Particle Size; Tissue Distribution
TL;DR:
A targeted drug delivery system that is accurately and quantitatively predicted to self-assemble into nanoparticles based on the molecular structures of precursor molecules, which are the drugs themselves.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 27, 2019
2018 journal article
The secondary structures of PEG-functionalized random copolymers derived from (R)- and (S)- families of alkyne polycarbodiimides
Polymer Chemistry.
Source: ORCID
Added: August 27, 2019
2018 journal article
Composite Ferroelectric and Plasmonic Particles for Hot Charge Separation and Photocatalytic Hydrogen Gas Production
ACS APPLIED ENERGY MATERIALS, 1(9), 4606–4616.
author keywords: Pt-end-capped gold nanorods; ferroelectrics; surface plasmon resonance; hot electrons; photocatalysts; H-2 production
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2019
2018 journal article
Charge generation dynamics in polymer nonfullerene solar cells with low energy loss
JOURNAL OF PHOTONICS FOR ENERGY, 8(3).
author keywords: nonfullerene acceptors; charge transfer; charge separation; energy loss; heterojunction
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 11, 2019
2018 journal article
Using 3D printed physical models to monitor knowledge integration in biochemistry
CHEMISTRY EDUCATION RESEARCH AND PRACTICE, 19(4), 1199–1215.
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Source: Web Of Science
Added: February 4, 2019
2018 journal article
Re-sensitizing Multidrug Resistant Bacteria to Antibiotics by Targeting Bacterial Response Regulators: Characterization and Comparison of Interactions between 2-Aminoimidazoles and the Response Regulators BfmR from Acinetobacter baumannii and QseB from Francisella spp.
FRONTIERS IN MOLECULAR BIOSCIENCES, 5.
author keywords: biofilms; antibiotic resistance; two-component systems; response regulators; Acinetobacter baumannii; Francisella
TL;DR:
This work investigates the response regulator/2-AI interaction and looks at a wider library of 2-AI compounds, and establishes that Francisella tularensis/novicida, encoding for only three known response regulators, can be a model system to study the interaction between 2-AIs and response regulators.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: January 28, 2019
2018 journal article
Engineering enzymatic assembly lines for the production of new antimicrobials
Current Opinion in Microbiology, 45, 140–148.
MeSH headings : Anti-Infective Agents / chemical synthesis; Anti-Infective Agents / chemistry; Anti-Infective Agents / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Metabolic Engineering; Peptide Synthases / chemistry; Peptide Synthases / genetics; Peptide Synthases / metabolism; Polyketide Synthases / chemistry; Polyketide Synthases / genetics; Polyketide Synthases / metabolism; Synthetic Biology
TL;DR:
The field is likely nearing the ability to design and build new biosynthetic pathways de novo, with various recent approaches taken towards this goal, focusing on the installation of new substrates, the swapping of enzymatic domains and modules, and the impact of metabolic engineering and synthetic biology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: January 21, 2019
2018 journal article
Low-Dimensional Magnetic Properties of Natural and Synthetic Mixite (Bi,Ca)Cu-6(OH)(6)(AsO4)(3)center dot nH(2)O (n approximate to 3) and Goudeyite YCu6(OH)(6)(AsO4)(3)center dot nH(2)O (n approximate to 3)
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE, 644(24), 1782–1790.
author keywords: Cu minerals; Mixite; Goudeyite; Magnetic properties; Low-dimensional antiferromagnet; Alternating Heisenberg chain
Source: Web Of Science
Added: January 14, 2019
2018 journal article
Activating the Growth of High Surface Area Alumina Using a Liquid Galinstan Alloy
ACS OMEGA, 3(12), 16409–16415.
TL;DR:
A correlation between the initial concentration of aluminum in the alloy and the surface area of the alumina product was found to peak at ∼30% Al, suggesting a novel route to the formation of amorphous alumina aerogel-type materials.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
7. Affordable and Clean Energy
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 14, 2019
2018 journal article
Extender Unit Promiscuity and Orthogonal Protein Interactions of an Aminomalonyl-ACP Utilizing Trans-Acyltransferase from Zwittermicin Biosynthesis
ACS Chemical Biology, 13(12), 3361–3373.
MeSH headings : Acyl Carrier Protein / chemistry; Acyl Carrier Protein / genetics; Acyl Carrier Protein / metabolism; Acyltransferases / chemistry; Acyltransferases / genetics; Acyltransferases / metabolism; Bacillus thuringiensis / enzymology; Bacillus thuringiensis / genetics; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Catalytic Domain; Coenzyme A Ligases / metabolism; Escherichia coli / genetics; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Polyketide Synthases / chemistry; Polyketide Synthases / genetics; Polyketide Synthases / metabolism; Protein Binding; Protein Engineering / methods; Rhizobium / enzymology; Substrate Specificity; Transferases (Other Substituted Phosphate Groups) / metabolism
TL;DR:
A method to access a panel of non-natural and non-native ACP-linked extender units was developed and used to probe the promiscuity of ZmaF, revealing one of the most promiscuous ATs characterized to date.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 14, 2019
2018 journal article
A Nonlinear, “Sticky” Web of Study for Chemistry: A Graphical Curricular Tool for Teaching and Learning Chemistry Built upon the Interconnection of Core Chemical Principles
Journal of Chemical Education, 95(12), 2134–2140.
author keywords: High School/Introductory Chemistry; First-Year Undergraduate/General; Curriculum; Inquiry-Based/Discovery Learning; Problem Solving/Decision Making; Learning Theories; Standards National/State
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: January 14, 2019
2018 article
Red and near-infrared fluorophores inspired by chlorophylls. Consideration of practical brightness in multicolor flow cytometry and biomedical sciences
(S. Achilefu & R. Raghavachari, Eds.). REPORTERS, MARKERS, DYES, NANOPARTICLES, AND MOLECULAR PROBES FOR BIOMEDICAL APPLICATIONS X, Vol. 10508.
Contributors: M. Taniguchi n , G. Hu n, R. Liu n, H. Du n & J. Lindsey n
Ed(s): S. Achilefu & R. Raghavachari
author keywords: Bacteriochlorophyll; Chlorophyll; Flow cytometry; Fluorophores; Multicolor; Near infrared; Stokes shift; Tandem dye
TL;DR:
The spectroscopic features of (bacterio)chlorins are evaluated quantitatively to illustrate practical brightness for this novel class of fluorophores in a prospective 8-color panel.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 14, 2019
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