College of Veterinary Medicine Administration

Works Published in 2010

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Displaying works 21 - 40 of 40 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Passive transfer of maternal immunoglobulin isotype antibodies against tetanus and influenza and their effect on the response of foals to vaccination

Equine Veterinary Journal, 33(7), 644–650.

By: W. Wilson*, J. Mihalyi*, S. Hussey* & D. Lunn*

author keywords: horse; foals; vaccination; maternal antibodies; immunoglobulin; influenza; tetanus
MeSH headings : Adjuvants, Immunologic / administration & dosage; Animals; Animals, Newborn / immunology; Animals, Suckling / immunology; Antibodies, Bacterial / blood; Antibodies, Viral / blood; Colostrum / immunology; Female; Horse Diseases / immunology; Horse Diseases / microbiology; Horse Diseases / virology; Horses; Immunity, Maternally-Acquired; Immunoglobulin G / analysis; Immunoglobulin G / blood; Influenza Vaccines / administration & dosage; Influenza Vaccines / immunology; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / veterinary; Pregnancy; Tetanus / immunology; Tetanus / veterinary; Tetanus Toxoid / administration & dosage; Tetanus Toxoid / immunology; Time Factors; Vaccination / methods; Vaccination / veterinary; Vaccines, Inactivated / administration & dosage; Vaccines, Inactivated / immunology
TL;DR: Based on the finding that maternal antibodies exert a significant inhibitory effect on the response of foals to tetanus toxoid and inactivated influenza antigens, it is recommended that primary immunisation of foal born to vaccinated mares should not commence before age 6 months. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

A new modified live equine influenza virus vaccine: phenotypic stability, restricted spread and efficacy against heterologous virus challenge

Equine Veterinary Journal, 33(7), 630–636.

By: T. Chambers*, R. Holland*, L. Tudor*, H. Townsend*, A. Cook*, J. Bogdan*, D. Lunn*, S. Hussey* ...

author keywords: horse; intranasal; antigenic drift; backpassage; challenge; cold-adapted; modified-live virus
MeSH headings : Administration, Intranasal; Animals; Female; Horse Diseases / prevention & control; Horse Diseases / transmission; Horses; Influenza A virus / immunology; Influenza Vaccines / administration & dosage; Influenza Vaccines / immunology; Influenza Vaccines / standards; Male; Nebulizers and Vaporizers / veterinary; Orthomyxoviridae Infections / prevention & control; Orthomyxoviridae Infections / transmission; Orthomyxoviridae Infections / veterinary; Phenotype; Safety; Serial Passage; Time Factors; Treatment Outcome; Vaccination / veterinary; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / immunology; Vaccines, Attenuated / standards; Virus Shedding
TL;DR: Results demonstrate that Flu Avert IN vaccine is safe and phenotypically stable, has low spontaneous transmissibility and is effective in protecting horses against challenge viruses representative of those in circulation worldwide. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Onset of immunoglobulin production in foals

Equine Veterinary Journal, 35(6), 620–622.

By: D. Holznagel*, S. Hussey*, J. Mihalyi*, W. Wilson* & D. Lunn*

author keywords: horse; foal; IgG subclass; antibody; maternal antibody
MeSH headings : Animals; Animals, Newborn / blood; Animals, Newborn / immunology; Colostrum / immunology; Horses / blood; Horses / immunology; Immunity, Maternally-Acquired; Immunoglobulin A / biosynthesis; Immunoglobulin A / blood; Immunoglobulin G / biosynthesis; Immunoglobulin G / blood; Immunoglobulins / biosynthesis; Immunoglobulins / blood
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Report of the Second Havemeyer EHV-1 Workshop, Steamboat Springs, Colorado, USA, September 2008

Equine Veterinary Journal, 42(6), 572–575.

By: J. Kydd*, J. Slater*, N. Osterrieder*, D. Antczak* & D. Lunn*

author keywords: horse; EHV-1; report; Havemeyer Foundation; equine herpesvirus myeloencephalopathy
MeSH headings : Animals; Colorado; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid; Horse Diseases / epidemiology; Horse Diseases / virology; Horses
TL;DR: This report summarises the findings of the Second Havemeyer EHV-1 Workshop, which was held in Steamboat Springs, Colorado, USA in September 2008 and summarizes the key advances identified during and since the meeting. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Control of EHV-1 viremia and nasal shedding by commercial vaccines

Vaccine, 28(32), 5203–5211.

By: L. Goehring*, B. Wagner*, R. Bigbie*, S. Hussey*, S. Rao*, P. Morley*, D. Lunn*

author keywords: EHV-1; Horses; Immunity; Vaccination
MeSH headings : Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; Antibody Formation; Female; Herpesviridae Infections / immunology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / immunology; Horse Diseases / immunology; Horse Diseases / prevention & control; Horses / immunology; Immunization Schedule; Neutralization Tests; Nose / immunology; Single-Blind Method; Viral Vaccines / immunology; Viremia / prevention & control; Viremia / veterinary; Virus Shedding
TL;DR: It is demonstrated that both commercial vaccines significantly suppressed EHV-1 disease and nasal viral shedding, and one vaccine suppressed days of viremia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Onset and duration of immunity to equine influenza virus resulting from canarypox-vectored (ALVAC®) vaccination

Veterinary Immunology and Immunopathology, 135(1-2), 100–107.

By: G. Soboll*, S. Hussey*, J. Minke*, G. Landolt*, J. Hunter, S. Jagannatha*, D. Lunn*

author keywords: ALVAC (R)-influenza vaccination; Horse; Influenza virus
MeSH headings : Animals; Antibodies, Viral / blood; Antibody Formation / immunology; Canarypox virus; Horse Diseases / immunology; Horse Diseases / prevention & control; Horse Diseases / virology; Horses / immunology; Influenza A Virus, H3N8 Subtype / immunology; Influenza Vaccines / immunology; Influenza Vaccines / therapeutic use; Male; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / prevention & control; Orthomyxoviridae Infections / veterinary; Vaccines, Synthetic / immunology; Vaccines, Synthetic / therapeutic use; Virus Shedding / immunology
TL;DR: The results of this study clearly demonstrate the early onset, and 6-month duration of protective immunity resulting from ALVAC-influenza vaccination against challenge with American lineage equine influenza viruses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Vaccination of ponies with the IE gene of EHV-1 in a recombinant modified live vaccinia vector protects against clinical and virological disease

Veterinary Immunology and Immunopathology, 135(1-2), 108–117.

By: G. Soboll*, C. Breathnach*, J. Kydd*, S. Hussey*, R. Mealey* & D. Lunn*

author keywords: EHV-1; Horses; Immediate early gene; Vaccination; IFN gamma
MeSH headings : Animals; Antibodies, Neutralizing / blood; Female; Genes, Immediate-Early / genetics; Genes, Immediate-Early / immunology; Genotype; Herpesviridae Infections / immunology; Herpesviridae Infections / prevention & control; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / genetics; Herpesvirus 1, Equid / immunology; Herpesvirus Vaccines / genetics; Herpesvirus Vaccines / immunology; Herpesvirus Vaccines / therapeutic use; Horse Diseases / immunology; Horse Diseases / prevention & control; Horses / immunology; Horses / virology; Interferon-gamma / blood; Male; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology; Vaccines, Synthetic / therapeutic use; Vaccinia; Viremia / immunology; Viremia / veterinary
TL;DR: This is an important study showing that vaccination of ponies with the EHV-1 IE protein provides not only reduction in clinical disease but also reduction of cell associated viremia, which is a prerequisite for the prevention of abortion and neurological disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Immune responses of Asian elephants (Elephas maximus) to commercial tetanus toxoid vaccine

Veterinary Immunology and Immunopathology, 133(2-4), 287–289.

By: W. Lindsay, E. Wiedner, R. Isaza*, H. Townsend*, M. Boleslawski* & D. Lunn*

author keywords: Asian elephant; Elephas maximus; Tetanus toxoid; Vaccination; Vaccine titer; Immunosenescence
MeSH headings : Age Factors; Animal Husbandry / methods; Animals; Animals, Zoo / immunology; Antibodies, Bacterial / biosynthesis; Antibodies, Bacterial / blood; Clostridium tetani / immunology; Elephants / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Immunization Schedule; Immunization, Secondary / veterinary; Male; Species Specificity; Tetanus / immunology; Tetanus / prevention & control; Tetanus / veterinary; Tetanus Toxoid / administration & dosage; Time Factors
TL;DR: The great majority of elephants had titers prior to booster vaccination, and following revaccination all elephants demonstrated anamnestic increases in titers, indicating that this species does respond to tetanus vaccination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

The Effect of Age on the Immune Response of Horses to Vaccination

Journal of Comparative Pathology, 142, S85–S90.

By: T. Muirhead*, J. McClure*, J. Wichtel*, H. Stryhn*, R. Markham*, D. McFarlane*, D. Lunn*

author keywords: geriatric; horse; immunosenescence; vaccination
MeSH headings : Age Factors; Aging / immunology; Animals; Horse Diseases / immunology; Horses / immunology; Immunization, Secondary; Immunologic Memory / immunology; Influenza A Virus, H3N8 Subtype / immunology; Influenza Vaccines / immunology; Orthomyxoviridae Infections / immunology; Rabies Vaccines / immunology; Vaccination / veterinary
TL;DR: Healthy aged horses mounted a primary immune response to rabies vaccine that was similar to that of younger adult horses, however, aged horses had a significantly reduced anamnestic response to influenza vaccination in comparison with the younger adult Horses, even though the pre-vaccination antibody titres of aged horses were higher. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

Molecular Investigation of the Viral Kinetics of Equine Herpesvirus-1 in Blood and Nasal Secretions of Horses after Corticosteroid-Induced Recrudescence of Latent Infection

Journal of Veterinary Internal Medicine, 24(5), 1153–1157.

By: N. Pusterla*, S. Hussey*, S. Mapes*, C. Johnson*, J. Collier*, J. Hill*, D. Lunn*, W. Wilson*

author keywords: EHV-1; Reactivation; Transmission
MeSH headings : Adrenal Cortex Hormones / pharmacology; Animals; Dexamethasone / pharmacology; Herpesvirus 1, Equid / physiology; Horse Diseases / blood; Horse Diseases / immunology; Horse Diseases / virology; Horses; Male; Mucus / virology; Time Factors; Virus Latency / drug effects; Virus Replication / physiology
TL;DR: EHV-1 was successfully reactivated after corticosteroid administration in latently infected horses, however, transmission of reactivated virus to sentinel horses was unsuccessful. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: July 27, 2019

2010 journal article

The prevalence of albuminuria in dogs and cats in an ICU or recovering from anesthesia

JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 20(5), 479–487.

author keywords: microalbuminuria; urine albumin
MeSH headings : Albuminuria / veterinary; Anesthesia / veterinary; Anesthesia Recovery Period; Animals; Cat Diseases / urine; Cats; Dog Diseases / urine; Dogs; Intensive Care Units
TL;DR: The prevalence of albuminuria in animals admitted to the ICU or recovering from anesthesia is higher than reported previously and transient in some patients, and the presence ofalbuminuria may be a negative prognostic indicator in this population of animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Randomised controlled clinical trial for the use of deracoxib during intense rehabilitation exercises after tibial plateau levelling osteotomy

VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY, 23(5), 332–335.

By: W. Gordon-Evans, D. Dunning*, A. Johnson & K. Knap

author keywords: NSAID; non-steroidal anti-inflammatory drugs; rehabilitation; exercise; TPLO; tibial plateau levelling osteotomy
MeSH headings : Animals; Anterior Cruciate Ligament / surgery; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Dog Diseases / surgery; Dogs; Osteotomy / adverse effects; Osteotomy / veterinary; Physical Conditioning, Animal / methods; Posterior Cruciate Ligament / surgery; Range of Motion, Articular; Rehabilitation / methods; Stress, Mechanical; Sulfonamides / therapeutic use
TL;DR: It was showed that treatment with deracoxib did not provide better outcomes when dogs were subjected to intense rehabilitation after tibial plateau levelling osteotomy, and each patient should be evaluated individually to determine if administration of derac oxib is appropriate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Learning-Style Profiles of 150 Veterinary Medical Students

JOURNAL OF VETERINARY MEDICAL EDUCATION, 37(4), 347–352.

By: J. Neel n & C. Grindem*

Contributors: J. Neel n & C. Grindem*

author keywords: learning styles; education; veterinary
MeSH headings : Cognition; Education, Veterinary; Humans; Learning; Models, Psychological; North Carolina; Psychological Tests; Psychology, Educational; Schools, Veterinary; Students, Health Occupations / psychology
TL;DR: The results show that although people have dominant learning-style preference and patterns, they have significant minor preferences and patterns across all dimensions with moderate to strong preferences on each scale, indicating that a balanced approach to teaching is essential to allow all students to learn optimally. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Outcome assessment of a computer-animated model for learning about the regulation of glomerular filtration rate

ADVANCES IN PHYSIOLOGY EDUCATION, 34(2), 97–105.

author keywords: medical education; veterinary; interactive; renal physiology
MeSH headings : Computer Simulation; Education, Veterinary / methods; Glomerular Filtration Rate / physiology; Humans; Physiology / education; Problem-Based Learning / methods
TL;DR: It is suggested that the animated model is a useful, effective, and well-received tool for learning and creating a visual memory of the regulatory mechanisms of GFR. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Francisella philomiragia Septicemia in a Dog

JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(4), 969–972.

By: M. Cora n, J. Neel n, J. Tarigo n, K. Post* & J. Barnes n

Contributors: M. Cora n, J. Neel n, J. Tarigo n, K. Post* & J. Barnes n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents / therapeutic use; Dog Diseases / blood; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Francisella / classification; Gram-Negative Bacterial Infections / drug therapy; Gram-Negative Bacterial Infections / microbiology; Gram-Negative Bacterial Infections / veterinary; Male; Prednisone / therapeutic use; Sepsis / blood; Sepsis / drug therapy; Sepsis / microbiology; Sepsis / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(9), 4437–4446.

By: J. Harned n, J. Ferrell n, M. Lall n, L. Fleisher n, S. Nagar n, M. Goralska n, M. McGahan n

MeSH headings : Animals; Apoferritins / genetics; Apoferritins / metabolism; Cell Nucleus / metabolism; Cells, Cultured; Culture Media, Conditioned / pharmacology; Cystine / pharmacokinetics; Dogs; Epithelial Cells / cytology; Epithelial Cells / metabolism; Glutathione / metabolism; Homeostasis / physiology; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A / metabolism
TL;DR: Iron storage in ferritin was greatly reduced by FHsiRNA, resulting in increased iron availability, as noted by a decrease in transferrin receptor levels and iron uptake from transferrin, and profound effects clearly demonstrate that maintenance of a specific H:L ratio is part of a basic cellular homeostatic mechanism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 article

MARCKS-related peptide modulates in vivo the secretion of airway Muc5ac (Retracted article. See vol. 309, pg. L 750, 2015)

Foster, W. M., Adler, K. B., Crews, A. L., Potts, E. N., Fischer, B. M., & Voynow, J. A. (2010, September). AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol. 299, pp. L345–L352.

By: W. Foster*, K. Adler n, A. Crews n, E. Potts*, B. Fischer* & J. Voynow*

author keywords: myristoylated alanine-rich C kinase substrate; airway hyperresponsiveness; elastase; serotonin
MeSH headings : Aerosols; Animals; Bronchoalveolar Lavage Fluid / chemistry; Cytokines / metabolism; Goblet Cells / pathology; Inflammation / prevention & control; Inflammation Mediators / metabolism; Intracellular Signaling Peptides and Proteins / antagonists & inhibitors; Leukocyte Elastase / pharmacology; Lung / drug effects; Lung / physiopathology; Male; Membrane Proteins / antagonists & inhibitors; Metaplasia / chemically induced; Methacholine Chloride / administration & dosage; Mice; Mice, Inbred BALB C; Mucin 5AC / antagonists & inhibitors; Mucin 5AC / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Peptide Fragments / pharmacology; Respiratory Hypersensitivity / chemically induced; Respiratory Hypersensitivity / physiopathology; Respiratory System / drug effects; Respiratory System / metabolism; Serotonin
TL;DR: The concept that even in airway epithelia remodeled with goblet cell metaplasia and in a state of mucin hypersecretion, exogenous attenuation of function of MARCKS protein via the MANS peptide decreases airway mucin secretion, inflammation, and hyperreactivity is supported. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

MARCKS and Related Chaperones Bind to Unconventional Myosin V Isoforms in Airway Epithelial Cells

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 43(2), 131–136.

By: K. Lin n, S. Fang n, J. Park n, A. Crews n & K. Adler n

author keywords: airway; mucin; MARCKS; chaperones; myosin
MeSH headings : Bronchi / pathology; Epithelial Cells / cytology; Gene Expression Regulation; HSP70 Heat-Shock Proteins / chemistry; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Models, Biological; Molecular Chaperones; Mucins / metabolism; Myosin Heavy Chains / chemistry; Myosin Type V / chemistry; Myristoylated Alanine-Rich C Kinase Substrate; Protein Binding; Protein Isoforms; Tetradecanoylphorbol Acetate / chemistry; Transfection
TL;DR: It is reported that myristoylated alanine-rich C kinase substrate (MARCKS) also interacts with unconventional myosin isoforms within these cells, and further molecular interactions between MARCKS and these chaperones/cytoskeletal proteins are elucidated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 article

What is your diagnosis? Nasal discharge from a dog

Piperisova, I., Neel, J. A., & Tarigo, J. (2010, March). VETERINARY CLINICAL PATHOLOGY, Vol. 39, pp. 121–122.

Contributors: I. Piperisova*, J. Neel* & J. Tarigo n

author keywords: Capillariasis; cytology; eggs; Eucoleus boehmi; nasal discharge
MeSH headings : Animals; Anthelmintics / therapeutic use; Capillaria / isolation & purification; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Enoplida Infections / diagnosis; Enoplida Infections / drug therapy; Enoplida Infections / pathology; Enoplida Infections / veterinary; Fenbendazole / therapeutic use; Male; Nose Diseases / drug therapy; Nose Diseases / parasitology; Nose Diseases / pathology; Nose Diseases / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

The hemodynamic effects of medetomidine continuous rate infusions in the dog

VETERINARY ANAESTHESIA AND ANALGESIA, 37(3), 197–206.

author keywords: cardiac output; CRI; medetomidine
MeSH headings : Analgesics, Non-Narcotic / administration & dosage; Analgesics, Non-Narcotic / pharmacology; Animals; Blood Gas Analysis / veterinary; Blood Pressure / drug effects; Cardiac Output / drug effects; Dogs; Dose-Response Relationship, Drug; Heart Rate / drug effects; Hemodynamics / drug effects; Infusions, Intravenous / veterinary; Medetomidine / administration & dosage; Medetomidine / pharmacology; Stroke Volume / drug effects; Vascular Resistance / drug effects
TL;DR: The demonstrated decrease in CO is largely because of bradycardia and the degree of cardiovascular depression appears to be dose-dependent, consistent with previously described hemodynamic changes with single bolus administration of medetomidine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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