Works Published in 2002
Displaying works 21 - 40 of 64 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2002 journal article
CEPH family 1362 STR database: An online resource for characterization of PCR products using electrospray ionization mass spectrometry
Journal of the American Society for Mass Spectrometry, 13(1), 89–90.
MeSH headings : DNA, Complementary / chemistry; Databases, Genetic; Genetic Markers; Humans; Internet; Polymerase Chain Reaction / methods; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Repeat Sequences / genetics
TL;DR:
An online database has been established in order to validate electrospray ionization mass spectrometry (ESI-MS) for genotyping and to publicize the procedures developed in the laboratory for the characterization of PCR products by ESI-MS.
(via Semantic Scholar)
link.springer.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2002 journal article
Saltatory Changes in the Structure of the Ribosomal DNA External Transcribed Spacer during the Evolution of Cockroaches of Genus Blattella
Doklady Biological Sciences, 387(1/6), 549–552.
MeSH headings : Animals; Base Sequence; Cockroaches / genetics; DNA, Complementary / metabolism; DNA, Ribosomal / chemistry; DNA, Ribosomal Spacer; Electrophoresis, Polyacrylamide Gel; Evolution, Molecular; Gene Deletion; Genetic Variation; Models, Genetic; Molecular Sequence Data; RNA, Ribosomal / genetics; Species Specificity; Transcription, Genetic
TL;DR:
The functional importance of the spacer sequences is confirmed by recent experimental data and may serve as enhancers and/or sequences responsible for binding to the regulatory protein factors; i.e., they play the key role in regulation of the rRNA gene promoter activity.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 5, 2020
2002 journal article
In the (adsorption) competition between NOM and MIB, who is the winner, and why?
Water Science and Technology: Water Supply, 2(2), 59–67.
Contributors: G. Newcombe*, J. Morrison, C. Hepplewhite & D. Knappe n
author keywords: activated carbon; adsorption; MIB; tastes and odours
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, ORCID
Added: August 28, 2020
2002 journal article
OLFACTORY TRANSPORT: A DIRECT ROUTE OF DELIVERY OF INHALED MANGANESE PHOSPHATE TO THE RAT BRAIN
Journal of Toxicology and Environmental Health, Part A, 65(20), 1493–1511.
MeSH headings : Administration, Inhalation; Analysis of Variance; Animals; Autoradiography; Axonal Transport; Brain / metabolism; Linear Models; Male; Manganese / administration & dosage; Manganese / pharmacokinetics; Nasal Mucosa / metabolism; Olfactory Bulb / metabolism; Rats; Spectrometry, Gamma
TL;DR:
The results demonstrate that the olfactory route contributes to 54 Mn delivery to the rat Olfactory bulb and tubercle, however, this pathway does not significantly contribute to striatal 54 Mn concentrations following a single, short-term inhalation exposure to54 MnHPO 4.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2002 journal article
Response Selectivity for Species-Specific Calls in the Inferior Colliculus of Mexican Free-Tailed Bats is Generated by Inhibition
Journal of Neurophysiology, 88(4), 1941–1954.
MeSH headings : Acoustic Stimulation; Animals; Bicuculline / pharmacology; Chiroptera / physiology; Discrimination Learning / drug effects; Discrimination Learning / physiology; GABA Antagonists / pharmacology; Inferior Colliculi / cytology; Inferior Colliculi / physiology; Neural Inhibition / drug effects; Neural Inhibition / physiology; Neurons / physiology; Pitch Perception / drug effects; Pitch Perception / physiology; Species Specificity; Vocalization, Animal / physiology
TL;DR:
The inhibition evoked by each call can shape a unique pattern of activity in the IC population and that pattern may be important for both the identification of a particular call and for discriminating it from other calls and other signals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2002 journal article
Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis
Proceedings of the National Academy of Sciences, 99(3), 1521–1526.
MeSH headings : Adenoma / pathology; Adenomatous Polyposis Coli / genetics; Animals; Carcinoma / pathology; Colonic Neoplasms / pathology; Crosses, Genetic; Disease Models, Animal; ErbB Receptors / antagonists & inhibitors; ErbB Receptors / deficiency; ErbB Receptors / genetics; ErbB Receptors / physiology; Homozygote; Humans; Intestinal Neoplasms / pathology; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mice, Nude; Signal Transduction; Transplantation, Heterologous; Tumor Cells, Cultured
TL;DR:
It is suggested that normal Egfr activity is required for establishment of intestinal tumors in the ApcMin model between initiation and subsequent expansion of initiated tumors, suggesting that Egfr inhibitors may be useful for advanced colorectal cancer treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2002 journal article
Lipophorin-facilitated hydrocarbon uptake by oocytes in the German cockroach Blattella germanica (L.)
JOURNAL OF EXPERIMENTAL BIOLOGY, 205(6), 781–790.
Contributors: Y. Fan, J. Chase, V. Sevala & C. Schal
Source: ORCID
Added: December 30, 2019
2002 journal article
Reproducibility of urinary phthalate metabolites in first morning urine samples.
Environmental Health Perspectives, 110(5), 515–518.
Contributors: J. Hoppin* , J. Brock*, B. Davis * & D. Baird*
author keywords: biologic markers; environmental exposure; phthalates; reliability; urine; women's health
MeSH headings : Adult; Biomarkers / analysis; Chromatography, High Pressure Liquid; Environmental Exposure; Female; Half-Life; Humans; Middle Aged; Phthalic Acids / urine; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Urinalysis
TL;DR:
The results suggest that even with the short half-lives of phthalates, women's patterns of exposure may be sufficiently stable to assign an exposure level based on a single first morning void urine measurement.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2019
2002 journal article
Prevalence of exposure to solvents, metals, grain dust, and other hazards among farmers in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 12(6), 418–426.
Contributors: J. Coble*, J. Hoppin* , L. Engel *, O. Elci *, M. Dosemeci*, C. Lynch *, M. Alavanja*
author keywords: confounding; exposure; farmers; pesticides
MeSH headings : Agriculture; Confounding Factors, Epidemiologic; Dust; Epidemiologic Studies; Female; Humans; Iowa / epidemiology; Male; Metals, Heavy / adverse effects; Metals, Heavy / analysis; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Occupational Health; Pesticides / adverse effects; Pesticides / analysis; Prevalence; Risk Assessment; Solvents / adverse effects; Solvents / analysis
TL;DR:
The associations between the use of pesticides and the frequency with which the farmers in the AHS reported performing various types of specific farming activities were assessed to evaluate potential confounding, suggesting the magnitude of bias due to confounding is likely to be minimal.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Potential for selection bias with tumor tissue retrieval in molecular epidemiology studies
Annals of Epidemiology, 12(1), 1–6.
Contributors: J. Hoppin* , P. Tolbert, J. Taylor, J. Schroeder & E. Holly
author keywords: molecular epidemiology; selection bias; tumor tissue
MeSH headings : Aged; California / epidemiology; Female; Humans; Male; Middle Aged; Molecular Epidemiology; Pancreatic Neoplasms / diagnosis; Pancreatic Neoplasms / epidemiology; Pancreatic Neoplasms / pathology; SEER Program; Selection Bias
TL;DR:
The potential for bias associated with differential availability of tumor blocks is discussed including consideration of tumor, patient, and hospital characteristics and the determinants of selection are described in all studies using tumor tissue.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2002 journal article
Chemical Predictors of Wheeze among Farmer Pesticide Applicators in the Agricultural Health Study
American Journal of Respiratory and Critical Care Medicine, 165(5), 683–689.
Contributors: J. Hoppin* , D. Umbach *, S. London *, M. Alavanja* & D. Sandler *
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Asthma / chemically induced; Asthma / epidemiology; Causality; Cohort Studies; Female; Humans; Iowa; Male; Middle Aged; North Carolina; Pesticides / adverse effects; Respiratory Sounds / etiology; Risk Factors
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: September 13, 2019
2002 journal article
Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: A population-based, case-control study in the Southeastern United States
Arthritis & Rheumatism, 46(7), 1840–1850.
Contributors: C. Parks, G. Cooper, L. Nylander-French, W. Sanderson, J. Dement, P. Cohen, M. Dooley, E. Treadwell
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Educational Status; Female; Humans; Logistic Models; Lupus Erythematosus, Systemic / chemically induced; Lupus Erythematosus, Systemic / epidemiology; Male; Middle Aged; Occupational Exposure; Prevalence; Racial Groups; Silicon Dioxide / adverse effects; Southeastern United States / epidemiology
TL;DR:
It is suggested that crystalline silica exposure may promote the development of SLE in some individuals and additional research is recommended in other populations.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 12(5), 313–318.
Contributors: J. Hoppin* , F. Yucel*, M. Dosemeci* & D. Sandler *
author keywords: accuracy; farmers; pesticides; pesticide registration; questionnaire
MeSH headings : Epidemiologic Studies; Humans; Mental Recall; Occupational Exposure; Pesticides / chemistry; Pesticides / classification; Quality Control; Reproducibility of Results; Retrospective Studies; Time Factors
TL;DR:
The quality of the self-reported pesticide product use history of 57,311 licensed pesticide applicators in the Agricultural Health Study is compared to the year the pesticide active ingredient was first registered for use to suggest participants provide plausible information regarding their pesticide use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
A Quantitative Approach for Estimating Exposure to Pesticides in the Agricultural Health Study
The Annals of Occupational Hygiene, 46(2), 245–260.
Contributors: M. Dosemeci*, M. Alavanja, A. Rowland, D. Mage, S. Hoar Zahm, N. Rothman, J. Lubin, J. Hoppin* , D. Sandler, A. Blair
author keywords: exposure assessment; pesticide exposure; agricultural exposures; farmers; pesticide applicators; occupational exposures
MeSH headings : Accidents, Occupational; Agriculture; Algorithms; Humans; Iowa; North Carolina; Occupational Exposure; Pesticides / poisoning; Prospective Studies; Protective Clothing; Risk Assessment / methods; Surveys and Questionnaires
TL;DR:
A quantitative method to estimate long-term chemical-specific pesticide exposures in a large prospective cohort study of more than 58000 pesticide applicators in North Carolina and Iowa found that the take-home questionnaire sub-cohort of applicators is representative of the entire cohort in terms of exposure.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2002 journal article
Neurobehavioral actions of coumestrol and related isoflavonoids in rodents
Neurotoxicology and Teratology, 24(1), 47–54.
author keywords: phytoestrogens; coumestrol; isoflavones; genistein; daidzein; endocrine disrupters; estrogen; sex behavior; ER alpha; ER beta
MeSH headings : Animals; Animals, Suckling; Coumestrol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression / drug effects; Isoflavones / pharmacology; Male; Mice; Rats; Receptors, Estrogen / genetics; Sexual Behavior, Animal / drug effects
TL;DR:
It is shown that even small, physiologically relevant exposure levels can alter estrogen-dependent gene expression in the brain and complex behavior, and that, in spite of their preferential affinity for ERbeta, isoflavonoids act through both ER(alpha) and ERbeta.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2002 journal article
Genistein Affects ERβ- But Not ERα-Dependent Gene Expression in the Hypothalamus
Endocrinology, 143(6), 2189–2197.
MeSH headings : Animals; Autoradiography; Brain Chemistry / drug effects; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens / blood; Estrogens, Non-Steroidal / blood; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression Regulation / drug effects; Genistein / blood; Genistein / pharmacology; Hypothalamus / drug effects; Hypothalamus / metabolism; In Situ Hybridization; Male; RNA, Messenger / biosynthesis; Radioimmunoassay; Rats; Rats, Long-Evans; Receptors, Estrogen / biosynthesis; Receptors, Estrogen / genetics; Receptors, Oxytocin / drug effects; Receptors, Oxytocin / metabolism; Sexual Behavior, Animal / drug effects; Sexual Maturation / physiology; Uterus / drug effects; Uterus / growth & development
TL;DR:
The impact of the soy isoflavone genistein, a major component of the supplement, on estrogen-dependent female sexual behavior and ERα- and ERβ-dependent gene expression in the rat brain is examined.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 18, 2019
2002 review
Zebrafish as an immunological model system
[Review of ]. MICROBES AND INFECTION, 4(14), 1469–1478.
author keywords: mutation screens; zebrafish genome project; transgenesis; developmental immunology; novel immune-type genes
MeSH headings : Animals; Fish Diseases / immunology; Immunity, Active / genetics; Immunity, Innate / physiology; Killer Cells, Natural / immunology; Models, Animal; Models, Immunological; Mutagenesis; Transgenes; Zebrafish / genetics; Zebrafish / immunology
TL;DR:
Two decades of research have established the zebrafish as a significant model system for studying vertebrate development and gene structure-function relationships and recent advances in mutation screening, the creation of genomic resources, and the development of efficient transgenesis procedures make this model increasingly attractive for immunological study.
(via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Cloning novel immune-type inhibitory receptors from the rainbow trout, Oncorhynchus mykiss
Immunogenetics, 54(9), 662–670.
TL;DR:
A comprehensive, phylogenetic analysis of NITRs from rainbow trout and three other major lineages of bony fish defines conserved families of N ITRs and suggests an ancient lineage of distinct groups of genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 journal article
BIVM, a Novel Gene Widely Distributed among Deuterostomes, Shares a Core Sequence with an Unusual Gene in Giardia lamblia
Genomics, 79(6), 750–755.
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Chromosome Mapping; Chromosomes, Human, Pair 13; Conserved Sequence; Gene Transfer, Horizontal; Genome, Human; Giardia lamblia / genetics; Humans; Immunoglobulins / genetics; Mice; Molecular Sequence Data; Organ Specificity; Protozoan Proteins; Vertebrates / genetics
TL;DR:
Characterization of BIVM in representative species demonstrates significant conservation throughout deuterostomes; however, an unusual gene has been identified in the protozoan pathogen Giardia lamblia that is similar to the core sequence of B IVM, suggesting the possibility of a horizontal gene transfer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2002 article
IL-13 induces intracellular translocation and release of TGF? in human bronchial epithelial cells in vitro.
American Journal of Respiratory and Critical Care Medicine, Vol. 165, p. A814.
Source: NC State University Libraries
Added: August 6, 2018
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