Aryssa Simpson

College of Engineering

Works (4)

Updated: April 25th, 2025 19:40

2024 journal article

A Functional RNA-Origami as Direct Thrombin Inhibitor with Fast-acting and Specific Single-Molecule Reversal Agents in vivo model

Molecular Therapy, 5.

By: A. Krissanaprasit*, E. Mihalko*, K. Meinhold n, A. Simpson*, J. Sollinger*, S. Pandit*, D. Dupont *, J. Kjems *, A. Brown* , T. LaBean*

MeSH headings : Animals; Mice; Humans; Aptamers, Nucleotide / pharmacology; Aptamers, Nucleotide / chemistry; Thrombin / metabolism; Blood Coagulation / drug effects; Tissue Distribution; RNA; Disease Models, Animal; Liver / metabolism; Liver / drug effects; Anticoagulants / pharmacology; Anticoagulants / chemistry; Antithrombins / pharmacology; Antidotes / pharmacology; Antidotes / chemistry
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; RNA Interference and Gene Delivery; Bacteriophages and microbial interactions; Extracellular vesicles in disease
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: May 17, 2024

2024 journal article

Peptide ligands for the universal purification of exosomes by affinity chromatography

Biotechnology and Bioengineering, 121(11), 3484–3501.

By: R. Kilgore n, B. Moore n, S. Sripada n, W. Chu n, S. Shastry n, E. Barbieri n, S. Hu n , W. Tian * ...

Contributors: R. Kilgore n, B. Moore n, S. Sripada n, W. Chu n, S. Shastry n, E. Barbieri n, S. Hu n , . al.

author keywords: affinity chromatography; bioseparations; exosomes; gene delivery; peptide ligands
MeSH headings : Exosomes / chemistry; Exosomes / metabolism; Chromatography, Affinity / methods; Ligands; Humans; Peptides / chemistry; Peptides / metabolism; Peptides / isolation & purification
topics (OpenAlex): Extracellular vesicles in disease; RNA Interference and Gene Delivery; Inhalation and Respiratory Drug Delivery; Lipid Membrane Structure and Behavior
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 14, 2024

2024 journal article

Utilizing multiscale engineered biomaterials to examine TGF‐β‐mediated myofibroblastic differentiation

Wound Repair and Regeneration, 3.

By: A. Simpson n, A. Krissanaprasit n, D. Chester n, C. Koehler n, T. LaBean n & A. Brown n 

author keywords: biomaterials; DNA origami; fibrosis; mechanotransduction; microgel; TGF-beta
MeSH headings : Cell Differentiation; Biocompatible Materials / pharmacology; Myofibroblasts / metabolism; Myofibroblasts / physiology; Transforming Growth Factor beta / metabolism; Extracellular Matrix / metabolism; Humans; Signal Transduction; Receptors, Transforming Growth Factor beta / metabolism; Cells, Cultured; Tissue Engineering / methods; Viscosity
topics (OpenAlex): Cellular Mechanics and Interactions; Cell Adhesion Molecules Research; 3D Printing in Biomedical Research
TL;DR: It is found that highly viscous materials with non-fixed TGF-β-R spacing promoted increased TGF-β signalling and myofibroblastic differentiation, likely due to the ability of cells to better cluster receptors on these surfaces. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 18, 2024

2022 journal article

Biomaterials for Hemostasis

Annual Review of Biomedical Engineering, 24(1), 111–135.

By: A. Simpson n, A. Shukla * & A. Brown n 

author keywords: hemostasis; trauma; clotting; sealant; synthetic blood product; layer-by-layer assembly
MeSH headings : Biocompatible Materials; Hemorrhage; Hemostasis; Hemostatics; Humans
topics (OpenAlex): Hemostasis and retained surgical items; Surgical Sutures and Adhesives; Polymer Surface Interaction Studies
TL;DR: This review article provides an overview of classes of materials used for topical hemostat and newer developments in the area of injectable hemostats for use in emergency medicine. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: July 11, 2022

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.