Bioinformatics Research Center

Works Published in 2022

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 journal article

Correlations between alignment gaps and nucleotide substitution or amino acid replacement

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(34).

TL;DR: A test of the null hypothesis that nucleotide substitution or amino acid replacement processes are independent of gap locations within sequence alignments is introduced, demonstrating the need for modifying the conventional approach of basing evolutionary inferences upon single optimal alignments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: July 31, 2023

2022 article

Convergent evolution of polyploid genomes from across the eukaryotic tree of life

Hao, Y., Fleming, J., Petterson, J., Lyons, E., Edger, P. P., Pires, J. C., … Conant, G. C. (2022, May 10). G3-GENES GENOMES GENETICS.

author keywords: polyploidy; convergent evolution; reciprocal gene loss; evolutionary model
MeSH headings : Diploidy; Eukaryota; Evolution, Molecular; Humans; Phylogeny; Polyploidy
TL;DR: By modeling the homoeologous gene losses that occurred in 50 genomes deriving from ten distinct polyploidy events, it is shown that the evolutionary forces acting on polyploids are remarkably similar, regardless of whether they occur in flowering plants, ciliates, fishes, or yeasts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: May 23, 2022

2022 journal article

Exome sequencing of hepatocellular carcinoma in lemurs identifies potential cancer drivers A pilot study

EVOLUTION MEDICINE AND PUBLIC HEALTH, 10(1), 221–230.

By: E. Gunady*, K. Ware*, S. Plumlee*, N. Devos*, D. Corcoran*, J. Prinz*, H. Misetic*, F. Ciccarelli* ...

author keywords: liver cancer; mutation; prosimians; non-human primates; TP53; ARID1A; CTNNB1
TL;DR: This pilot study suggests that human exome capture reagents are a promising tool for genomic studies of cancer in lemurs and other non-human primates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: May 23, 2022

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