Bioinformatics Research Center

Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2026 journal article

In-season yield forecasting using multitemporal remote sensing environmental observations and machine learning: Applications for sweetpotato in North Carolina, USA

European Journal of Agronomy.

By: M. Carbajal, D. Jones, C. Williams & N. Nelson

topics (OpenAlex):
Source: ORCID
Added: September 10, 2025

2025 article

Assessing contamination in DNA extraction kits commonly used for microbiome research

Rabasco, J. T., Kisthardt, S. C., Theriot, C. M., & Callahan, B. J. (2025, September 23).

By: J. Rabasco, S. Kisthardt, C. Theriot & B. Callahan

topics (OpenAlex):
Source: ORCID
Added: September 24, 2025

2025 article

IRIS Integrates Sparse Sequence, Experimental, and AI-Predicted Structures for Protein-RNA Affinity Prediction and Motif Discovery

Rosa, E. C., Zhang, Y., & Lin, X. (2025, September 16).

By: E. Rosa, Y. Zhang & X. Lin

topics (OpenAlex):
Source: ORCID
Added: September 16, 2025

2025 journal article

Organophosphate Flame Retardants Disrupt Autism-Relevant Gene Networks Across Development: A Cross-Species Multi-Omics Study

Environmental Research.

By: Y. Zhou n & G. Sun n

topics (OpenAlex): GDF15 and Related Biomarkers; RNA regulation and disease; RNA Research and Splicing
Source: ORCID
Added: September 15, 2025

2025 journal article

Reliability and Usefulness of Seedling Plant Data in Cassava Breeding

Plants.

By: C. Phumichai, H. Ceballos, P. Pleeprom, T. Chomsuk, P. Kongsil, W. Wannarat, W. Siriwan, T. Jaisuwan ...

topics (OpenAlex):
Source: ORCID
Added: September 12, 2025

2025 article

Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model

Song, Z., Tryndyak, V. P., Willett, R. A., Pogribny, I. P., Rusyn, I., & Wright, F. A. (2025, August 28). TOXICOLOGICAL SCIENCES.

author keywords: liver; steatohepatitis; fibrosis
topics (OpenAlex): Liver Disease Diagnosis and Treatment; Hepatitis B Virus Studies; Endoplasmic Reticulum Stress and Disease
Source: Web Of Science
Added: September 8, 2025

2025 article

Genetic linkage mapping in Megathyrsus maximus (Jacq.) with multiple dosage markers

Gesteira, G. de S., Ferreira, G. C., Mollinari, M., Santos, M. F., Jank, L., Vilela, M. de M., … Garcia, A. A. F. (2025, August 19). G3-GENES GENOMES GENETICS, Vol. 8.

By: G. Gesteira n, G. Ferreira*, M. Mollinari n, M. Santos, L. Jank, M. Vilela, A. Raposo, L. Chiari, Z. Zeng n, A. Garcia*

co-author countries: Brazil 🇧🇷
author keywords: linkage map; polyploid; autotetraploid; guineagrass
topics (OpenAlex): Genetic and phenotypic traits in livestock; Genetic and Environmental Crop Studies; Genetic diversity and population structure
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 journal article

Injection of vocal fold lamina propria-derived hydrogels modulates fibrosis in injured vocal folds

BIOMATERIALS ADVANCES, 178.

By: C. Mora-Navarro n, E. Smith n, Z. Wang n, M. Ramos-Alamo*, L. Collins n, N. Awad*, D. Cruz*, T. Tollison n ...

co-author countries: Puerto Rico 🇵🇷
author keywords: Vocal fold lamina propria; Fibrosis; Extracellular matrix; Hydrogels; TGF-(31
topics (OpenAlex): Voice and Speech Disorders; Dysphagia Assessment and Management; Tissue Engineering and Regenerative Medicine
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 journal article

Two-body triton photodisintegration and Wigner-SU(4) symmetry

PHYSICAL REVIEW C, 112(2).

By: X. Lin & J. Vanasse

topics (OpenAlex): Molecular spectroscopy and chirality; Advanced Chemical Physics Studies
Sources: Web Of Science, NC State University Libraries
Added: August 25, 2025

2025 article

VILMIR is a trans-acting long noncoding RNA that enhances the host interferon response in human epithelial cells

John, K., Smith, E., Istishin, A., Mahmood, N., Diveley, K., Tollison, T. S., … Peng, X. (2025, August 22).

By: K. John, E. Smith, A. Istishin, N. Mahmood, K. Diveley, T. Tollison, S. Carpenter, X. Peng

topics (OpenAlex):
Source: ORCID
Added: August 22, 2025

2025 article

Active regulation of the epidermal growth factor receptor by the membrane bilayer

Srinivasan, S., Lin, X., Chen, X., Regmi, R., Zhang, B., & Schlau-Cohen, G. S. (2025, August 18).

By: S. Srinivasan, X. Lin*, X. Chen, R. Regmi, B. Zhang & G. Schlau-Cohen

topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; HER2/EGFR in Cancer Research
Source: ORCID
Added: August 19, 2025

2025 article

Phased chromosome-level assembly provides insight into the genome architecture of hexaploid sweetpotato

Wu, S., Sun, H., Zhao, X., Hamilton, J. P., Mollinari, M., Gesteira, G. D. S., … Fei, Z. (2025, August 8). NATURE PLANTS, Vol. 8.

co-author countries: China 🇨🇳
topics (OpenAlex): Plant Virus Research Studies; Chromosomal and Genetic Variations; Cocoa and Sweet Potato Agronomy
Sources: Web Of Science, NC State University Libraries
Added: August 18, 2025

2025 article

KeySDL: Sparse Dictionary Learning for Keystone Microbe Identification

Gordon, M., Akyol, T. Y., Amos, B., Andersen, S. U., & Williams, C. (2025, August 11).

By: M. Gordon, T. Akyol, B. Amos, S. Andersen & C. Williams*

topics (OpenAlex): Gut microbiota and health; Bacterial Identification and Susceptibility Testing; Genomics and Phylogenetic Studies
Source: ORCID
Added: August 15, 2025

2025 article

Cervicovaginal microbial features predict <i>Chlamydia trachomatis</i> spread to the upper genital tract of infected women

Jeong, S., Tollison, T., Brochu, H., Chou, H., Huntress, I., Yount, K. S., … Peng, X. (2025, August 12). (M. Raffatellu, Ed.). INFECTION AND IMMUNITY, Vol. 8.

Ed(s): M. Raffatellu

author keywords: cervicovaginal microbiome; <italic>Chlamydia trachomatis</italic>; upper genital tract infection; 16S rRNA sequencing
topics (OpenAlex): Reproductive tract infections research; Pelvic floor disorders treatments; Urinary Tract Infections Management
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 12, 2025

2025 journal article

No more laborious stem counting: AI-powered computer vision enables identification and quantification of solid and hollow alfalfa stems at the pixel level

SMART AGRICULTURAL TECHNOLOGY, 12.

By: B. Weihs, Z. Tang, S. Roy*, Z. Tian, D. Heuschele, Z. Zhang, C. Williams*, Z. Zhang ...

author keywords: YOLO; Computer vision; Alfalfa; Image analysis; Pixel; Stem hollowness
topics (OpenAlex): Industrial Vision Systems and Defect Detection; Smart Agriculture and AI; Spectroscopy and Chemometric Analyses
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 8, 2025

2025 journal article

High-throughput classification and quantification of skinning phenotype in sweet potatoes

PLANT PHENOME JOURNAL, 8(1).

topics (OpenAlex): Postharvest Quality and Shelf Life Management; Plant tissue culture and regeneration; Plant Virus Research Studies
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 4, 2025

2025 journal article

Experimental Evolution of <i>Phytophthora infestans</i> on Tomato Reveals Rapid Genotypic and Phenotypic Adaptation and Dynamic RXLR Genome Variation

Phytopathology®, 115(8), 998–1007.

By: A. Coomber n, D. Rasmussen n & J. Ristaino n

author keywords: adaptation; experimental evolution; genomics; late blight; <italic>Phytophthora</italic>; RXLR; targeted sequencing; tomato
MeSH headings : Phytophthora infestans / genetics; Phytophthora infestans / physiology; Solanum lycopersicum / microbiology; Plant Diseases / microbiology; Plant Diseases / parasitology; Genotype; Phenotype; Genetic Variation; Adaptation, Physiological
topics (OpenAlex): Plant Pathogens and Resistance; Plant Disease Resistance and Genetics; Plant-Microbe Interactions and Immunity
Sources: ORCID, Web Of Science, NC State University Libraries, Crossref
Added: July 31, 2025

2025 article

Genomic Evaluation of Canine Prostatic Carcinomas as a Model for the Human Disease

Thomas, R., Luff, J. A., Dickey, A. N., Dillon, M. N., Livingston, I. G., Schrag, C. A., … Breen, M. (2025, July 23). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 7.

By: R. Thomas n, J. Luff n, A. Dickey n, M. Dillon n, I. Livingston n, C. Schrag n, S. Suter n, M. Breen n

author keywords: adenocarcinoma; DNA copy number variations; dogs; mutation; prostatic neoplasms; urologic neoplasms
topics (OpenAlex): Veterinary Oncology Research; Veterinary Medicine and Surgery; Human-Animal Interaction Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 28, 2025

2025 journal article

Spiner, deep learning-based automated detection of spiral ganglion neurons in intact cochleae

ISCIENCE, 28(7).

By: Y. Cai n, G. Leitz-Najarian*, R. Rosen n, K. Hutson*, A. Moatti n, C. Li n, D. Fitzpatrick*, A. Greenbaum n

topics (OpenAlex): Hearing Loss and Rehabilitation; Hearing, Cochlea, Tinnitus, Genetics; Structural Health Monitoring Techniques
Source: Web Of Science
Added: July 28, 2025

2025 journal article

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

GENOME RESEARCH, 35(7), 1485–1502.

MeSH headings : Humans; Quantitative Trait Loci; Liver / metabolism; Chromatin / genetics; Chromatin / metabolism; Genome-Wide Association Study; Gene Expression Regulation; Transcription Factors / metabolism; Binding Sites; Polymorphism, Single Nucleotide
topics (OpenAlex): Epigenetics and DNA Methylation; Genomics and Chromatin Dynamics; Genetics and Neurodevelopmental Disorders
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Signature gene expression model for quantitative evaluation of MASH-like liver injury in mice☆

TOXICOLOGY AND APPLIED PHARMACOLOGY, 502.

co-author countries: Canada 🇨🇦
author keywords: Mice; MASH; Liver Pathology; Transcriptomics; Machine Leaning Pathologist Assistance
MeSH headings : Animals; Male; Female; Mice; Disease Models, Animal; Diet, High-Fat / adverse effects; Liver / pathology; Liver / metabolism; Transcriptome; Gene Expression Profiling / methods; Collaborative Cross Mice; Fatty Liver / genetics; Fatty Liver / pathology; Fatty Liver / metabolism; Non-alcoholic Fatty Liver Disease / genetics; Non-alcoholic Fatty Liver Disease / pathology
topics (OpenAlex): Liver Disease Diagnosis and Treatment; Endoplasmic Reticulum Stress and Disease; Hepatocellular Carcinoma Treatment and Prognosis
Source: Web Of Science
Added: July 21, 2025

2025 journal article

Spatiotemporal dynamics of NF-κB/Dorsal inhibitor IκBα/Cactus in<i> Drosophila</i> blastoderm embryos

ISCIENCE, 28(7).

By: A. Schloop n, S. Hiremath n, R. Shaikh*, A. Bhakta*, C. Williams n, G. Reeves*, A. Schloop, S. Hiremath ...

topics (OpenAlex): Botanical Research and Applications; Neurobiology and Insect Physiology Research; Bioactive natural compounds
Sources: Web Of Science, NC State University Libraries
Added: July 21, 2025

2025 journal article

Interpretable protein-DNA interactions captured by structure-sequence optimization

ELife.

By: Y. Zhang n, I. Silvernail n, Z. Lin n & X. Lin n

topics (OpenAlex): RNA and protein synthesis mechanisms; Genomics and Chromatin Dynamics; DNA and Nucleic Acid Chemistry
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: July 17, 2025

2025 journal article

NIAGADS: A data repository for Alzheimer's disease and related dementia genomics

ALZHEIMERS & DEMENTIA, 21(6).

By: A. Kuzma*, O. Valladares*, E. Greenfest-Allen*, H. Nicaretta*, M. Kirsch*, Y. Ren*, Z. Katanic*, H. White* ...

author keywords: Alzheimer's disease; Alzheimer's disease and related dementias; Alzheimer's Disease Sequencing Project; bioinformatics; data repository; dementia; genetics; genomics; National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site; open access; qualified access; sequencing
MeSH headings : Humans; Alzheimer Disease / genetics; Genomics; United States; Databases, Genetic; National Institute on Aging (U.S.); Dementia / genetics; Genome-Wide Association Study; Information Dissemination
topics (OpenAlex): Genomics and Rare Diseases; Bioinformatics and Genomic Networks; Epigenetics and DNA Methylation
Sources: Web Of Science, NC State University Libraries
Added: July 17, 2025

2025 journal article

Structural variation detection and association analysis of whole-genome-sequence data from 16,543 Alzheimer's disease sequencing project subjects

ALZHEIMERS & DEMENTIA, 21(6).

By: H. Wang*, B. Dombroski*, P. Cheng*, A. Tucci n, Y. Si n, J. Farrell*, J. Tzeng n, Y. Leung* ...

author keywords: Alzheimer's disease; copy number variation; NCK2; RNA5SP293; structural variation
MeSH headings : Humans; Alzheimer Disease / genetics; Whole Genome Sequencing; Genetic Predisposition to Disease / genetics; LDL-Receptor Related Proteins / genetics; ATP-Binding Cassette Transporters / genetics; Membrane Transport Proteins / genetics; Male; Polymorphism, Single Nucleotide; Female; Linkage Disequilibrium; Amyloid beta-Protein Precursor / genetics; Genome-Wide Association Study
topics (OpenAlex): Genomics and Rare Diseases; RNA Research and Splicing; Genetic Associations and Epidemiology
Sources: Web Of Science, NC State University Libraries
Added: July 17, 2025

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