Bioinformatics Research Center

Recent Works

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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2026 article

MetaStrainer : Accurate reconstruction of bacterial strain genotypes from short-read metagenomic samples

Sharaf, H., & Bobay, L.-M. (2026, March 3).

topics (OpenAlex): Genomics and Phylogenetic Studies; Microbial Community Ecology and Physiology; Gut microbiota and health
Source: ORCID
Added: March 4, 2026

2026 article

A polygenic growth score and risk for large for gestational age birth weight

Aamir, M., Feghali, M., Yee, L., Silver, R. M., Durnwald, C., Steller, J. G., … Scifres, C. M. (2026, February 5). Journal of the Endocrine Society, Vol. 2.

By: M. Aamir n, M. Feghali*, L. Yee*, R. Silver*, C. Durnwald*, J. Steller*, D. Haas*, U. Reddy*, R. Guerrero n, C. Scifres*

topics (OpenAlex): Pregnancy and preeclampsia studies; Gestational Diabetes Research and Management; Birth, Development, and Health
Sources: NC State University Libraries, NC State University Libraries
Added: March 4, 2026

2026 article

BPS2026 – Integrating sparse sequence, experimental, and AI-predicted structures for protein-nucleic acid interaction predictions

Zhang, Y., Cisneros, E., Silvernail, I., Li, R., Thornton, T., & Lin, X. (2026, February 1). Biophysical Journal.

topics (OpenAlex): Protein Structure and Dynamics; Bioinformatics and Genomic Networks; Computational Drug Discovery Methods
Source: NC State University Libraries
Added: March 4, 2026

2026 article

Computational Framework for Therapeutic Target Discovery via Perturbation Simulation: Application to Cystic Fibrosis Airway Disease

Sun, G., & Zhou, Y.-H. (2026, March 3).

By: G. Sun & Y. Zhou

Source: ORCID
Added: March 4, 2026

2026 article

Fruit Composition Diversity among the North Carolina Strawberry Core Germplasm Collection

Haynes, B., Fernandez, G., Iorizzo, M., Ma, G., Ashrafi, H., & Perkins-Veazie, P. (2026, February 12). HortScience, Vol. 2.

By: B. Haynes n, G. Fernandez n, M. Iorizzo n, G. Ma n, H. Ashrafi n & P. Perkins-Veazie n

topics (OpenAlex): Berry genetics and cultivation research; Phytochemicals and Antioxidant Activities; Botanical Research and Applications
Sources: NC State University Libraries, NC State University Libraries
Added: March 4, 2026

2026 article

Quantitative Biology

Conant, G. (2026, January 5). CRC Press.

By: G. Conant*

topics (OpenAlex): Genetics, Bioinformatics, and Biomedical Research; Gene Regulatory Network Analysis; Evolution and Science Education
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: ORCID
Added: March 4, 2026

2026 article

KeySDL: sparse dictionary learning for keystone microbe identification from steady-state observations using a dynamical-systems model

Gordon, M., Akyol, T. Y., Amos, B., Andersen, S. U., & Williams, C. (2026, February 19). BioData Mining, Vol. 2.

By: M. Gordon n, T. Akyol*, B. Amos n, S. Andersen* & C. Williams n

co-author countries: Denmark 🇩🇰
topics (OpenAlex): Gene Regulatory Network Analysis; Gaussian Processes and Bayesian Inference; Model Reduction and Neural Networks
Sources: NC State University Libraries, NC State University Libraries
Added: March 2, 2026

2026 article

Hierarchical Multi-Omics Trajectory Prediction for Fecal Microbiota Transplantation: A Novel Machine Learning Framework for Small-Sample Longitudinal Multi-Omics Integration

Zhou, Y.-H., & Sun, G. (2026, February 23).

By: Y. Zhou n & G. Sun*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Gut microbiota and health; Barrier Structure and Function Studies
Source: ORCID
Added: February 23, 2026

2026 article

Cross-Species Exome Sequencing Reveals Recurrent Genomic Alterations in California Sea Lion (Zalophus californianus) Urogenital Carcinoma and Highlights a Recurrent PD-L1 Variant

Livingston, I. G., Wise, C. F., Dickey, A. N., Thomas, R., Deming, A. C., Halaska, B., … Breen, M. (2026, February 10). Genes, Vol. 2.

By: I. Livingston n, C. Wise n, A. Dickey n, R. Thomas n, A. Deming*, B. Halaska*, F. Gulland*, K. Colegrove*, P. Duignan*, M. Breen

topics (OpenAlex): Veterinary Oncology Research; Marine animal studies overview; Turtle Biology and Conservation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: February 12, 2026

2026 article

Recruitment of bifunctional regulator thermospermine to methylated ribosomes directs xylem fate

Ko, D., Ruonala, R., Faille, A., Hellmann, E., Help, H., Liu, H., … Helariutta, Y. (2026, February 12). Science.

By: D. Ko*, R. Ruonala*, A. Faille, E. Hellmann*, H. Help*, H. Liu*, R. Nielsen*, A. Haakonsson* ...

co-author countries: China 🇨🇳 Czechia 🇨🇿 Denmark 🇩🇰 Estonia 🇪🇪 Spain 🇪🇸 Finland 🇫🇮 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Poland 🇵🇱 Sweden 🇸🇪
MeSH headings : Ribosomes / metabolism; Methylation; Xylem / cytology; Xylem / metabolism; Xylem / growth & development; Arabidopsis / metabolism; Arabidopsis / genetics; Arabidopsis / cytology; Arabidopsis / growth & development; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Arabidopsis Proteins / chemistry; Methyltransferases / metabolism; Methyltransferases / genetics; Spermine / analogs & derivatives; Spermine / metabolism; RNA, Ribosomal / metabolism; Protein Biosynthesis; Polyamines / metabolism; RNA, Transfer / metabolism; Gene Expression Regulation, Plant
topics (OpenAlex): Polyamine Metabolism and Applications; RNA modifications and cancer; Cancer-related gene regulation
Source: ORCID
Added: February 12, 2026

2026 article

A biophysical framework for accurately identifying antigen single-amino acid escape variants and corresponding variant-specific compensatory TCR sequences

Ghoreyshi, Z. S., Levine, H., Lin, X., Onuchic, J. N., & George, J. T. (2026, February 5). (Vol. 2). Vol. 2.

By: Z. Ghoreyshi*, H. Levine*, X. Lin n, J. Onuchic* & J. George*

topics (OpenAlex): vaccines and immunoinformatics approaches; Monoclonal and Polyclonal Antibodies Research; T-cell and B-cell Immunology
Sources: NC State University Libraries, NC State University Libraries
Added: February 7, 2026

2026 article

A deep-learning-based score to evaluate multiple sequence alignments

Serok, N., Polonsky, K., Ashkenazy, H., Mayrose, I., Thorne, J. L., & Pupko, T. (2026, February 5).

By: N. Serok*, K. Polonsky*, H. Ashkenazy*, I. Mayrose*, J. Thorne n & T. Pupko*

co-author countries: Germany 🇩🇪 Israel 🇮🇱
topics (OpenAlex): Genomics and Phylogenetic Studies; Evolution and Paleontology Studies; Genome Rearrangement Algorithms
Source: NC State University Libraries
Added: February 7, 2026

2026 article

Discovery of a major QTL for resistance to Fusarium wilt ( Fusarium oxysporum f. sp. batatas ) in the hexaploid Covington sweetpotato

Fraher, S., Kinczyk, J., Siqueira Gesteira, G., Heim, C., Williamson, S., Olukolu, B. A., … Yencho, G. C. (2026, January 1). Crop Science, Vol. 1.

By: S. Fraher n, J. Kinczyk n, G. Siqueira Gesteira n, C. Heim n, S. Williamson n, B. Olukolu*, G. Silva Pereira*, M. Mollinari n ...

co-author countries: Brazil 🇧🇷
topics (OpenAlex): Plant Pathogens and Fungal Diseases; Plant Pathogenic Bacteria Studies; Plant Pathogens and Resistance
Sources: NC State University Libraries, NC State University Libraries
Added: February 2, 2026

2026 article

Active regulation of the epidermal growth factor receptor by the membrane bilayer

Srinivasan, S., Lin, X., Chen, X., Regmi, R., Zhang, B., & Schlau-Cohen, G. S. (2026, January 20).

topics (OpenAlex): Lipid Membrane Structure and Behavior; Caveolin-1 and cellular processes; Protein Kinase Regulation and GTPase Signaling
Source: ORCID
Added: February 1, 2026

2026 article

Pathogenic bacterial species and the microbiome of cat fleas (Ctenocephalides felis) inhabiting flea-infested homes

Gin, T. E., Moore, C. O., Tomlinson, T., Wilson, G., Gray, A., Sutherland, C., … Callahan, B. (2026, January 30). PLoS ONE, Vol. 1.

By: T. Gin n, C. Moore n, T. Tomlinson*, G. Wilson*, A. Gray*, C. Sutherland*, K. Miller*, K. Li* ...

MeSH headings : Animals; Cats; Ctenocephalides / microbiology; Microbiota / genetics; Dogs; RNA, Ribosomal, 16S / genetics; Flea Infestations / veterinary; Flea Infestations / parasitology; Flea Infestations / microbiology; Bacteria / genetics; Bacteria / classification; Bacteria / isolation & purification; Phylogeny; Cat Diseases / parasitology; Bartonella / genetics; Bartonella / isolation & purification
topics (OpenAlex): Bartonella species infections research; Vector-borne infectious diseases; Vector-Borne Animal Diseases
Sources: NC State University Libraries, NC State University Libraries
Added: February 1, 2026

2026 article

Prevalence and Evolutionary Implications of Genome Rearrangements in Bacteria

Martinez-Gutierrez, C. A., Huang, Y., & Bobay, L.-M. (2026, January 14). (R. Hershberg, Ed.). Genome Biology and Evolution.

Ed(s): R. Hershberg

topics (OpenAlex): Genome Rearrangement Algorithms; Bacterial Genetics and Biotechnology; Genomics and Phylogenetic Studies
Source: ORCID
Added: January 15, 2026

2026 article

Genetic variation in a plant-parasitic nematode is associated with gene expression changes conserved across evolutionarily distant host plants

Nielsen, D. M. (2026, January 12).

By: D. Nielsen n

topics (OpenAlex): Nematode management and characterization studies; Plant Parasitism and Resistance; Plant nutrient uptake and metabolism
Source: ORCID
Added: January 12, 2026

2026 article

Inferring toxicant susceptibility in global populations from gene-environment interactions involving the Aryl Hydrocarbon Receptor

Chimeh, U. S., Rogers, M. C., & Aylor, D. L. (2026, January 10).

topics (OpenAlex): Genetic Associations and Epidemiology; Toxic Organic Pollutants Impact; Carcinogens and Genotoxicity Assessment
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: NC State University Libraries, ORCID
Added: January 12, 2026

2025 article

An approach to uncover significant direct and mediated relationships in multi-dimensional new approach methods (NAMs) data: A case study of hazard evaluation of petroleum UVCBs

Zhou, Y.-H., Gallins, P. J., Rusyn, I., & Wright, F. A. (2025, May 28). The Science of The Total Environment.

MeSH headings : Petroleum / toxicity; Petroleum / analysis; Humans; Polycyclic Aromatic Hydrocarbons / analysis; Polycyclic Aromatic Hydrocarbons / toxicity; Environmental Monitoring / methods; Hazardous Substances / toxicity; Hazardous Substances / analysis; Transcriptome
topics (OpenAlex): Atmospheric and Environmental Gas Dynamics; Oil Spill Detection and Mitigation; Microbial bioremediation and biosurfactants
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
Source: NC State University Libraries
Added: March 4, 2026

2025 article

BPS2025 - Advanced deep learning model to predict DNA-DNA binding interactions

Matange, K. R., Brihadiswaran, G., Tomek, K. J., Tuck, J. M., & Keung, A. J. (2025, February 1). Biophysical Journal, Vol. 2.

topics (OpenAlex): Computational Drug Discovery Methods
Sources: NC State University Libraries, NC State University Libraries
Added: March 4, 2026

2025 article

Selective Enrichment and Functional Preservation of Treg Cells during IL-2 Mutein-Mediated Expansion and Contraction

Schiliró, D., Sun, M., Lopez, J., Tollison, T., Smith, E., Tunbridge, M., … Kwun, J. (2025, August 1). American Journal of Transplantation.

By: D. Schiliró*, M. Sun*, J. Lopez*, T. Tollison n, E. Smith n, M. Tunbridge*, A. Martinino*, J. O'Neil* ...

topics (OpenAlex): Immune Cell Function and Interaction; T-cell and B-cell Immunology; Immunotherapy and Immune Responses
Source: NC State University Libraries
Added: March 4, 2026

2025 article

Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and bis-N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice

Moran, E., Goodman, S., Wright, F. A., Evans, R., Tretyakova, N. Y., & Rusyn, I. (2025, October 3). Toxics.

topics (OpenAlex): Carcinogens and Genotoxicity Assessment; Effects and risks of endocrine disrupting chemicals; Toxic Organic Pollutants Impact; Indoor Air Quality and Microbial Exposure
Source: NC State University Libraries
Added: March 4, 2026

2025 article

A Reference-Quality NLRome for the Hexaploid Sweetpotato and Diploid Wild Relatives

Parada-Rojas, C. H., Childs, K. L., Soto, M. F., Salcedo, A., Pecota, K., Yencho, G. C., … Quesada-Ocampo, L. M. (2025, January 1). Molecular Plant-Microbe Interactions.

co-author countries: France 🇫🇷
MeSH headings : Ipomoea batatas / genetics; Ipomoea batatas / immunology; Diploidy; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Polyploidy; Genome, Plant / genetics; NLR Proteins / genetics; NLR Proteins / metabolism; Genotype; Plant Diseases / immunology; Genetic Variation
topics (OpenAlex): Plant Virus Research Studies; Plant Pathogenic Bacteria Studies; Plant-Microbe Interactions and Immunity
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: ORCID
Added: March 2, 2026

2025 article

Mesopolyploidy as a taxonomic clade marker for Brassica and relatives (tribe Brassiceae)

Thomas, S. K., Abrahams, R. S., Kick, D. R., Walden, N., Conant, G., McKain, M. R., … Pires, J. C. (2025, August 2). Annals of Botany.

co-author countries: Austria 🇦🇹 Colombia 🇨🇴 Czechia 🇨🇿 Germany 🇩🇪 Ecuador 🇪🇨 Netherlands 🇳🇱
topics (OpenAlex): Chromosomal and Genetic Variations; Nitrogen and Sulfur Effects on Brassica; Plant Diversity and Evolution
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: ORCID
Added: March 2, 2026

2025 article

Missing mate pairs reported as poly-G reads can confound analyses of rare members of microbial assemblages

Dhillon, A. K., Workman, A., Kuehn, L. A., Earley, B., Cosby, S. L., Powell, A. J., … Conant, G. C. (2025, August 22). Ecological Genetics and Genomics.

By: A. Dhillon n, A. Workman*, L. Kuehn*, B. Earley*, S. Cosby, A. Powell*, T. McDaneld*, G. Conant n

co-author countries: France 🇫🇷 Ireland 🇮🇪
topics (OpenAlex): Gut microbiota and health; Microbial Community Ecology and Physiology; Genomics and Phylogenetic Studies
Source: ORCID
Added: March 2, 2026

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