Bioinformatics Research Center

Works Published in 2023

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Displaying all 5 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2023 journal article

Interlocus Gene Conversion, Natural Selection, and Paralog Homogenization

MOLECULAR BIOLOGY AND EVOLUTION, 40(9).

author keywords: interlocus gene conversion; paralog homogenization; teleost genome duplication
Source: Web Of Science
Added: April 1, 2024

2023 journal article

Yearly variation coupled with social interactions shape the skin microbiome in free-ranging rhesus macaques

MICROBIOLOGY SPECTRUM, 11(5).

author keywords: skin microbiome; rhesus macaques; social behavior; year-to-year environment; Cayo Santiago; primates; microbial diversity; 16S rRNA
TL;DR: The findings indicate that social dynamics interact with yearly environmental changes to shape the skin microbiota in rhesus macaques, with potential implications for understanding the factors affecting the microbiome in humans, which share many biological and social characteristics with these animals. (via Semantic Scholar)
Source: Web Of Science
Added: January 2, 2024

2023 journal article

Cytoplasmic male sterility and abortive seed traits generated through mitochondrial genome editing coupled with allotopic expression of atp1 in tobacco

FRONTIERS IN PLANT SCIENCE, 14.

By: R. Dewey n, D. Selote n, H. Griffin n, A. Dickey n, D. Jantz*, J. Smith*, A. Matthiadis*, J. Strable n, C. Kestell n, W. Smith n

author keywords: hybrid seed systems; allotopic expression; stenospermocarpy; atp1; transgene containment; substoichiometric shifting; mitoarcus; custom-designed meganucleases
TL;DR: Should the results reported here in tobacco prove to be translatable to other crop species, then multiple applications of allotopic expression of an essential mitochondrial gene followed by its elimination through genome editing can be envisaged. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: October 16, 2023

2023 article

Scalable Bayesian Divergence Time Estimation With Ratio Transformations

Ji, X., Fisher, A. A., Su, S., Thorne, J. L., Potter, B., Lemey, P., … Suchard, M. A. (2023, July 17). SYSTEMATIC BIOLOGY.

author keywords: Bayesian inference; divergence time estimation; effective sample size; Hamiltonian Monte Carlo; pathogens; phylogenetics; ratio transformation
TL;DR: A ratio transformation is explored that maps the original N-1 internal node heights into a space of one height parameter and N-2 ratio parameters and improves inference efficiency by at least 5-fold and makes it computationally feasible to incorporate mixed-effects molecular clock models for the Ebola virus example. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: September 5, 2023

2023 journal article

Analysis of reproducibility and robustness of a renal proximal tubule microphysiological system OrganoPlate 3-lane 40 for in vitro studies of drug transport and toxicity

TOXICOLOGICAL SCIENCES.

By: C. Sakolish*, H. Moyer*, H. Tsai*, L. Ford*, A. Dickey n, F. Wright n, G. Han*, P. Bajaj* ...

author keywords: kidney; in vitro models; validation
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: September 5, 2023

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