Center for Human Health and the Environment

Works Published in 2005

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Displaying works 21 - 40 of 148 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 conference paper

Characterization of Salmonella Isolates From A Commercial Laying Hen Complex by Serotype, Antibiotic Susceptibility Test and PFGE

Li, X., Levine, J., & Sheldon, B. (2005, July). Presented at the Poultry Science Association Annual Meeting, Auburn, Alabama.

By: X. Li, J. Levine & B. Sheldon

Event: Poultry Science Association Annual Meeting at Auburn, Alabama

Source: NC State University Libraries
Added: September 30, 2021

2005 conference paper

In vitro Sensitivity and Specificity Analysis of Spring Viremia of Carp Virus Diagnostic Tests

Shivappa, R., Kozlowicz, S., Corsin, F., & Levine, J. F. (2005, June). Presented at the 30th Annual Eastern Fish Health Workshop, Shepardstown, West Virginia.

By: R. Shivappa, S. Kozlowicz, F. Corsin & J. Levine

Event: 30th Annual Eastern Fish Health Workshop at Shepardstown, West Virginia

Source: NC State University Libraries
Added: September 30, 2021

2005 journal article

‘Close-fitting sleeves’: DNA damage recognition by the UvrABC nuclease system

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 577(1-2), 92–117.

By: B. Van Houten*, D. Croteau*, M. DellaVecchia*, H. Wang* & C. Kisker*

author keywords: protein-DNA interaction; bacterial nucleotide excision repair; DNA damage recognition
MeSH headings : DNA Damage; Endodeoxyribonucleases / chemistry; Endodeoxyribonucleases / genetics; Endodeoxyribonucleases / metabolism; Escherichia coli Proteins / chemistry; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Models, Molecular; Substrate Specificity
TL;DR: The current knowledge of how damage recognition is achieved in bacterial nucleotide excision repair through the concerted action of the UvrA, UvrB, and UvrC proteins is reviewed. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 23, 2021

2005 journal article

Structural insights into the first incision reaction during nucleotide excision repair

The EMBO Journal, 24(5), 885–894.

By: J. Truglio, B. Rhau, D. Croteau, L. Wang, M. Skorvaga, E. Karakas, M. DellaVecchia, H. Wang, B. Van Houten, C. Kisker

Source: ORCID
Added: September 23, 2021

2005 journal article

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Nature, 438(7069), 803–819.

By: K. Lindblad-Toh, C. Wade, T. Mikkelsen, E. Karlsson, D. Jaffe, M. Kamal, M. Clamp, J. Chang ...

MeSH headings : Animals; Conserved Sequence / genetics; Dog Diseases / genetics; Dogs / classification; Dogs / genetics; Evolution, Molecular; Female; Genome / genetics; Genomics; Haplotypes / genetics; Humans; Hybridization, Genetic; Male; Mice; Mutagenesis / genetics; Polymorphism, Single Nucleotide / genetics; Rats; Short Interspersed Nucleotide Elements / genetics; Synteny / genetics
TL;DR: A high-quality draft genome sequence of the domestic dog is reported, together with a dense map of single nucleotide polymorphisms (SNPs) across breeds, to shed light on the structure and evolution of genomes and genes. (via Semantic Scholar)
Source: Crossref
Added: September 18, 2021

2005 journal article

Copepod grazing impact on the trophic structure of the microbial assemblage of the San Pedro Channel, California

Journal of Plankton Research, 27(10), 959–971.

TL;DR: The copepod-protozoan trophic link appears to be a key factor structuring the planktonic microbial assemblage in the San Pedro Channel. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: August 4, 2021

2005 chapter

Design and use of a highly responsive and rigidly controllable hypoxia exposure system

In G. K. Ostrander (Ed.), Techniques in Aquatic Toxicology (Vol. 2).

By: D. Lehmann, J. Levine* & J. Law

Ed(s): G. Ostrander

Sources: Crossref, NC State University Libraries
Added: April 26, 2021

2005 journal article

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease.

Neurobiology of Aging, 8.

By: T. Williams*, B. Lynn*, W. Markesbery* & M. Lovell*

author keywords: early Alzheimer's disease; Mild Cognitive Impairment; lipid peroxidation; oxidative stress; Alzheimer's disease
MeSH headings : Acrolein / metabolism; Aged, 80 and over; Aldehydes / metabolism; Alzheimer Disease / metabolism; Biomarkers / metabolism; Brain / metabolism; Cognition Disorders / metabolism; Female; Humans; Lipid Peroxidation; Male; Tissue Distribution
TL;DR: The results suggest that lipid peroxidation occurs early in the pathogenesis of AD, and levels of HNE in HPG and SMTG and a significant increase in acrolein in all three brain regions studied. (via Semantic Scholar)
Source: ORCID
Added: April 8, 2021

2005 journal article

Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry.

Analytical Chemistry, 5(10), 3383–3389.

Contributors: T. Williams*, M. Lovell* & B. Lynn*

MeSH headings : Acrolein / analysis; Acrolein / metabolism; Aldehydes / analysis; Aldehydes / metabolism; Alzheimer Disease / etiology; Alzheimer Disease / pathology; Biomarkers / analysis; Biomarkers / metabolism; Chromatography, Liquid / methods; Humans; Lipid Peroxidation; Tandem Mass Spectrometry / methods; Tissue Distribution
TL;DR: The LC-MS/MS methodology developed here will be used in subsequent studies to determine aldehyde concentrations for comparing age-matched controls to AD tissues from human subjects. (via Semantic Scholar)
Source: ORCID
Added: April 8, 2021

2005 journal article

Reproducibility of Retention Time using a Splitless nanoLC Coupled to an ESI-FTICR Mass Spectrometer

Journal of Biomolecular Techniques, 16, 4, 414–422.

By: D. Muddiman, C. Mason & K. Johnson

Source: NC State University Libraries
Added: March 17, 2021

2005 journal article

Rapid estrogenic regulation of extracellular signal-regulated kinase 1/2 signaling in cerebellar granule cells involves a G protein- and protein kinase A-dependent mechanism and intracellular activation of protein phosphatase 2A

Endocrinology, 146(12), 5397–5406.

By: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

Contributors: S. Belcher*, H. Le*, L. Spurling* & J. Wong*

MeSH headings : Animals; Cells, Cultured; Cerebellum / cytology; Cerebellum / metabolism; Cyclic AMP-Dependent Protein Kinases / physiology; Enzyme Activation / physiology; Estradiol / pharmacology; Estrogens / physiology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; GTP-Binding Proteins / physiology; Intracellular Membranes / enzymology; Male; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3 / metabolism; Neurons / metabolism; Pertussis Toxin / pharmacology; Phosphoprotein Phosphatases / metabolism; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects; Signal Transduction / physiology; Time Factors
TL;DR: The presented evidence indicates that the rapid effects of estrogens on ERK signaling in cerebellar granule cells are induced through a novel G protein-coupled receptor mechanism that requires PKA and Src-kinase activity to link E(2) to the ERK/MAPK signaling module. (via Semantic Scholar)
Source: ORCID
Added: March 5, 2021

2005 journal article

Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: Potent nongenomic agonist and endocrine disrupting activity of the xenoestrogen bisphenol A

Endocrinology, 146(12), 5388–5396.

By: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

Contributors: A. Zsarnovszky*, H. Le*, H. Wang* & S. Belcher*

MeSH headings : Aging / metabolism; Animals; Animals, Newborn; Benzhydryl Compounds; Cerebellar Cortex / enzymology; Dose-Response Relationship, Drug; Drug Combinations; Endocrine System / drug effects; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / pharmacology; Extracellular Signal-Regulated MAP Kinases / metabolism; Female; Immunohistochemistry; Male; Phenols / administration & dosage; Phenols / pharmacology; Rats; Rats, Sprague-Dawley; Signal Transduction / drug effects
TL;DR: It is shown that ERK1/2 signaling in the cerebellum of neonatal and mature rats was rapidly responsive to E(2) and during development to the environmental estrogen bisphenol A (BPA) and the ability of BPA to act as a highly potent E( 2) mimetic and to also disrupt the rapid actions of E(3) at very low concentrations during cerebellar development highlights the potential low-dose impact of xenoestrogens on the developing (via Semantic Scholar)
Source: ORCID
Added: March 5, 2021

2005 journal article

Nucleic Acid Analysis by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry at the Beginning of the Twenty-First Century

Current Pharmaceutical Design, 11(20), 2593–2613.

By: J. Frahm & D. Muddiman*

author keywords: FT-ICR; Fourier transform ion cyclotron resonance; mass spectrometry; DNA; RNA; PNA
MeSH headings : Nucleic Acids / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Electrospray Ionization / trends; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / trends; Spectroscopy, Fourier Transform Infrared / methods; Spectroscopy, Fourier Transform Infrared / trends; Spectrum Analysis / methods; Spectrum Analysis / trends; Technology, Pharmaceutical / instrumentation; Technology, Pharmaceutical / methods; Technology, Pharmaceutical / trends
TL;DR: A diverse range of studies including fundamental studies of nucleic acid properties, improvements in sample clean up and preparation, better methods to obtain higher mass measurement accuracy, analysis of noncovalent complexes, tandem mass spectrometry, and characterization of peptide nucleic acids are presented. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021

2005 journal article

Primary Trabecular Meshwork Cells Incubated in Human Aqueous Humor Differ from Cells Incubated in Serum Supplements

Investigative Opthalmology & Visual Science, 46(8), 2848.

By: M. Fautsch, K. Howell, A. Vrabel, M. Charlesworth*, D. Muddiman* & D. Johnson

MeSH headings : Adult; Aged; Aged, 80 and over; Aqueous Humor / physiology; Ascorbic Acid / metabolism; Ascorbic Acid / pharmacology; Blotting, Western; Cell Culture Techniques; Cell Proliferation; Culture Media; Cytoskeletal Proteins / metabolism; Dexamethasone / pharmacology; Electrophoresis, Gel, Two-Dimensional; Eye Proteins / metabolism; Female; Glycoproteins / metabolism; Humans; Infant; Male; Middle Aged; Serum; Tissue Inhibitor of Metalloproteinase-1 / metabolism; Trabecular Meshwork / cytology; Trabecular Meshwork / drug effects; Trabecular Meshwork / metabolism
TL;DR: Addition of human aqueous humor rather than FBS to trabecular monolayer cell cultures triggers significant changes in cellular and molecular characteristics. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021

2005 journal article

Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants

Journal of Exposure Science & Environmental Epidemiology, 16(1), 39–48.

By: J. Hoppin*, R. Ulmer*, A. Calafat*, D. Barr*, S. Baker*, H. Meltzer*, K. Rønningen*

author keywords: sample storage and shipment; cohort studies; analytical chemistry; urine
MeSH headings : Environmental Exposure; Environmental Pollutants / urine; Humans; Mass Spectrometry; Reproducibility of Results; Specimen Handling; Temperature; Time Factors; Urinalysis / methods
TL;DR: In general, most analytes were stable under all conditions with changes in mean concentration over time, temperature, and preservative being generally less than 20%, with the exception of the OP metabolites in the presence of boric acid. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021

2005 journal article

Quantitative Protein Expression Analysis Of CLL B Cells from Mutated and Unmutated IgVHSubgroups Using Acid-Cleavable Isotope-Coded Affinity Tag Reagents

Journal of Proteome Research, 4(4), 1310–1317.

By: D. Barnidge*, D. Jelinek*, D. Muddiman* & N. Kay*

author keywords: CLL; B cell; quantitative comparison; clCAT; UM-CLL; M-CLL; linear ion trap mass spectrometer
MeSH headings : B-Lymphocytes / chemistry; B-Lymphocytes / immunology; Cell Fractionation; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains / genetics; Immunoglobulin Heavy Chains / immunology; Immunoglobulin Variable Region / genetics; Immunoglobulin Variable Region / immunology; Isotope Labeling / methods; Leukemia, Lymphocytic, Chronic, B-Cell / immunology; Mass Spectrometry / methods; Mutation; Proteome / analysis
TL;DR: Stable isotope labeling and mass spectrometry can complement 2D gel electrophoresis and gene microarray technologies for identifying putative and perhaps unique prognostic markers in CLL. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 18, 2021

2005 journal article

752. Equine Infectious Anemia Virus Pseudotyped with the Vesicular Stomatitis Virus G-Protein, Preferentially Targets Neural Precursors in the Adult Mouse Brain

Molecular Therapy, 11(Supplement 1), S292.

By: T. Ghashghaei, M. Patel, J. Olsen & E. Anton

TL;DR: The preferential targeting of GFAP+ astrocytes in the SVZ by the EIAV lentivirus is potentially useful for the molecular manipulation of these stem cells. (via Semantic Scholar)
Source: Crossref
Added: December 29, 2020

2005 journal article

Expert's opinion on potential role of epithelial cells in pathogenesis of organ dysfunction

Journal of Organ Dysfunction, 1(1), 24–25.

By: K. Adler n

Source: Crossref
Added: December 29, 2020

2005 chapter

Biochemistry and Molecular Biology of Pheromone Production

In Comprehensive Molecular Insect Science (Vol. 3, pp. 705–751).

By: G. Blomquist*, R. Jurenka*, C. Schal n & C. Tittiger*

UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: November 20, 2020

2005 journal article

Analysis of the RELN gene as a genetic risk factor for autism

Molecular Psychiatry, 10(6), 563–571.

By: D. Skaar*, Y. Shao*, J. Haines*, J. Stenger*, J. Jaworski*, E. Martin*, G. DeLong*, J. Moore* ...

author keywords: autism; candidate gene; chromosome 7q; RELN; association
MeSH headings : 5' Untranslated Regions / genetics; Autistic Disorder / genetics; Cell Adhesion Molecules, Neuronal / genetics; Chromosomes, Human, Pair 7 / genetics; Extracellular Matrix Proteins / genetics; Female; Genetic Predisposition to Disease / genetics; Genotype; Humans; Infant; Linkage Disequilibrium; Male; Nerve Tissue Proteins / genetics; Pedigree; Polymorphism, Single Nucleotide / genetics; Reelin Protein; Serine Endopeptidases / genetics; White People / genetics
TL;DR: Combined analyses show the potential of RELN as an important contributor to genetic risk in autism and test for association of single-locus markers and multilocus haplotypes with autism. (via Semantic Scholar)
Source: Crossref
Added: November 2, 2020

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