Center for Environmental and Health Effects of PFAS

Works Published in 2009

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Displaying works 81 - 91 of 91 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Coupling of a vented column with splitless nanoRPLC-ESI-MS for the improved separation and detection of brain natriuretic peptide-32 and its proteolytic peptides

Journal of Chromatography B, 877(10), 948–954.

By: G. Andrews n, C. Shuford n, J. Burnett*, A. Hawkridge n & D. Muddiman n

author keywords: Vented column; BNP-32; Splitless nanoLC; Tryptic digestion
MeSH headings : Amino Acid Sequence; Brain Chemistry; Chromatography, Liquid / methods; Molecular Sequence Data; Natriuretic Peptide, Brain / chemistry; Natriuretic Peptide, Brain / isolation & purification; Natriuretic Peptide, Brain / pharmacokinetics; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: It is demonstrated that the use of free cysteine as an alkylation quenching agent and a secondary digestion within the digestion scheme can provide targeted tryptic peptides with increased abundances, which will serve to further augment the detection of BNP-32 by LC-MS. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Use of Life-Cycle Analysis To Support Solid Waste Management Planning for Delaware

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 43(5), 1264–1270.

By: P. Kaplan n, S. Ranjithan n & M. Barlaz n

MeSH headings : Conservation of Natural Resources / economics; Cost-Benefit Analysis; Delaware; Environmental Pollutants; Greenhouse Effect; Models, Chemical; Planning Techniques; Refuse Disposal / economics; Refuse Disposal / methods; Uncertainty; Waste Management / economics; Waste Management / methods
TL;DR: The results show that implementing a landfill diversion strategy for only a portion of the population is most cost-effective for meeting a county-specific landfill diversion target, and implementation of waste-to-energy offers the mostcost-effective opportunity for GHG emissions reductions. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Intact and Top-Down Characterization of Biomolecules and Direct Analysis Using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization Coupled to FT-ICR, Mass Spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(4), 667–673.

MeSH headings : Amino Acid Sequence; Animals; Carbohydrates / chemistry; Cattle; Chickens; Egg Yolk / chemistry; Horses; Lipids / chemistry; Milk / chemistry; Molecular Sequence Data; Mucins / chemistry; Mucins / metabolism; Myoglobin / chemistry; Polysaccharides / chemistry; Polysaccharides / metabolism; Proteins / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectroscopy, Fourier Transform Infrared / methods
TL;DR: Three of the four classes of biological macromolecules have been ionized and detected using MALDESI with minimal sample preparation and Sequencing of O-linked glycans, cleaved from mucin using reductive β-elimination chemistry, is also demonstrated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Generation of Multiply Charged Peptides and Proteins by Radio Frequency Acoustic Desorption and Ionization for Mass Spectrometric Detection

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(4), 597–600.

By: R. Dixon n, J. Sampson n & D. Muddiman n

MeSH headings : Electrodes; Equipment Design; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Natriuretic Peptide, Brain / chemistry; Peptides / chemistry; Proteins / chemistry; Quartz / chemistry; Ubiquitin / chemistry
TL;DR: The design and implementation of a radio frequency acoustic desorption ionization (RADIO) source has been demonstrated and intact and dissociated species observed during MS and MS/MS experiments, respectively are confirmed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Absolute Quantification of C-Reactive Protein in Human Plasma Derived from Patients with Epithelial Ovarian Cancer Utilizing Protein Cleavage Isotope Dilution Mass Spectrometry

JOURNAL OF PROTEOME RESEARCH, 8(2), 1085–1090.

By: D. Williams n & D. Muddiman n

author keywords: absolute quantification; C-reactive protein; ovarian cancer; single reaction monitoring
MeSH headings : Amino Acid Sequence; C-Reactive Protein / chemistry; C-Reactive Protein / metabolism; Chromatography, Liquid / methods; Female; Humans; Isotope Labeling / methods; Mass Spectrometry / methods; Molecular Sequence Data; Ovarian Neoplasms / blood; Ovarian Neoplasms / chemistry; Peptides / chemistry; Peptides / genetics; Peptides / metabolism; Reproducibility of Results
TL;DR: Interestingly, the PC-IDMS method provided concentration values that were approximately 10x the concentration reported by the ELISA method, which demonstrated that the method of detection is an important consideration when determining reference ranges of a particular analyte. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Mercury(II) Bioaccumulation and Antioxidant Physiology in Four Aquatic Insects

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 43(3), 934–940.

By: L. Xie n, J. Flippin n, N. Deighton n, D. Funk n, D. Dickey n & D. Buchwalter n

MeSH headings : Animals; Antioxidants / metabolism; Insecta / metabolism; Mercury / metabolism; Species Specificity; Subcellular Fractions / metabolism; Water Pollutants, Chemical / metabolism
TL;DR: Surprisingly, little Hg (<10%) was found in the heat-stable cytosolic protein subcellular compartment in each of the four species, suggesting that Hg was not well detoxified. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Development of a nanoLC LTQ Orbitrap Mass Spectrometric Method for Profiling Glycans Derived from Plasma from Healthy, Benign Tumor Control, and Epithelial Ovarian Cancer Patients

ANALYTICAL CHEMISTRY, 81(3), 1130–1136.

By: M. Bereman n, T. Williams n & D. Muddiman n

MeSH headings : Biomarkers, Tumor / blood; Biomarkers, Tumor / chemistry; Carcinoma / diagnosis; Chromatography, Liquid / methods; Female; Genital Neoplasms, Female / chemistry; Genital Neoplasms, Female / diagnosis; Glycoproteins / blood; Glycoproteins / chemistry; Humans; Hydrophobic and Hydrophilic Interactions; Lectins / blood; Lectins / chemistry; Male; Ovarian Neoplasms / diagnosis; Polysaccharides / blood; Polysaccharides / chemistry; ROC Curve; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: A split-less nano-flow liquid chromatography mass spectrometric analysis of glycans chemically cleaved from glycoproteins in plasma shows similar column efficiencies and excellent retention time reproducibility without an internal standard to correct for retention time shift. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Aquatic animal models of human disease: Selected papers and recommendations from the 4th Conference

Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 149(2), 121–128.

By: D. Hinton*, R. Hardman*, S. Kullman n, J. Law n, M. Schmale*, R. Walter*, R. Winn*, J. Yoder n

MeSH headings : Animals; Disease Models, Animal; Fishes; Humans; Mollusca
TL;DR: Of increasing importance are contributions of aquatic invertebrates and fishes to the detection of toxic responses from: metal mining and smelting impacts, polycyclic aromatichydrocarbons and persistent organic pollutants and their adverse effects in harbors and coastal estuaries, including the verification of remediation processes. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Form, function and phylogenetics of NITRs in bony fish

Developmental & Comparative Immunology, 33(2), 135–144.

By: J. Yoder n

author keywords: Teleost; Innate immunity; Natural killer receptors; ITIM; ITSM; DAP12; CD8; KIR
MeSH headings : Animals; DNA, Complementary / genetics; Fishes / genetics; Fishes / immunology; Humans; Immunoglobulins / immunology; Ligands; Phylogeny; Receptors, Immunologic / chemistry; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology
TL;DR: An analysis of all published NITRs demonstrates the conserved nature of multiple residues within the NITR Ig domains permitting the identification of NITr ESTs from salmon, cod, halibut, lake whitefish and stickleback species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

A genetic algorithm-based procedure for 3D source identification at the Borden emplacement site

JOURNAL OF HYDROINFORMATICS, 11(1), 51–64.

By: X. Jin n, G. Mahinthakumar n, E. Zechman* & R. Ranjithan n

author keywords: environmental forensics; evolutionary computation; groundwater source identification; inverse problems
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Light-activation of gene function in mammalian cells via ribozymes

Chem. Commun., (5), 568–570.

By: D. Young n, R. Garner n, J. Yoder n & A. Deiters n

MeSH headings : Cell Line; Gene Expression / radiation effects; Humans; RNA, Catalytic / chemistry; RNA, Catalytic / metabolism; RNA, Messenger / metabolism; Toyocamycin / chemistry; Toyocamycin / radiation effects; Ultraviolet Rays
TL;DR: A ribozyme based gene control element enabled the spatio-temporal regulation of gene function in mammalian cell culture with light. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

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