Works Published in 2009

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Displaying works 301 - 320 of 632 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Lactational Transfer of Manganese in Rats: Predicting Manganese Tissue Concentration in the Dam and Pups from Inhalation Exposure with a Pharmacokinetic Model

TOXICOLOGICAL SCIENCES, 112(1), 23–43.

By: M. Yoon*, A. Nong*, H. Clewell*, M. Taylor, D. Dorman n & M. Andersen*

author keywords: manganese; inhalation exposure; postnatal period; enhanced biliary excretion; homeostasis during lactation; PBPK
MeSH headings : Animals; Animals, Newborn; Female; Inhalation Exposure; Lactation; Manganese / administration & dosage; Manganese / pharmacokinetics; Milk / chemistry; Models, Biological; Pregnancy; Rats; Tissue Distribution
TL;DR: The successful description of Mn kinetics across these life stages suggests that the present model can help describe the relationship between dose of exposure and target tissue Mn concentrations across different developmental stages and its potential risks and assess whether infants and children should be regarded as susceptible populations for Mn inhalation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Lack of Impact of Den Interference on Neonatal Red Wolves

SOUTHEASTERN NATURALIST, 8(4), 631–638.

By: K. Beck*, C. Lucash* & M. Stoskopf*

TL;DR: No biologically important difference in the proportion of pups surviving was observed between subsequent visits, nor in comparison to historical data from dens where pups were not handled but rather documented based on autumn trapping surveys. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct

AUTOIMMUNITY, 42(8), 678–691.

By: E. Young*, P. Hess n, L. Arnold*, R. Tisch* & J. Frelinger*

author keywords: Autoimmunity; FoxP3; IGRP; IL-4; naive T-cell
MeSH headings : Age Factors; Animals; B-Lymphocytes / cytology; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes / cytology; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; Cell Count; Diabetes Mellitus, Type 1 / immunology; Female; Forkhead Transcription Factors / metabolism; Glucose-6-Phosphatase / immunology; Interleukin-4 / metabolism; Islets of Langerhans / cytology; Islets of Langerhans / immunology; Lymph Nodes / cytology; Lymph Nodes / immunology; Lymphocyte Subsets / cytology; Lymphocyte Subsets / immunology; Male; Mice; Mice, Inbred NOD; Pancreas / cytology; Pancreas / immunology; Pancreatitis / immunology; Proteins / immunology; Sex Characteristics; Spleen / cytology; Spleen / immunology; T-Lymphocyte Subsets / cytology; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism; T-Lymphocytes, Regulatory / cytology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; Th2 Cells / cytology; Th2 Cells / immunology; Th2 Cells / metabolism
TL;DR: The underlying immunological processes in both male and female NOD mice are similar while the rates differ and the presence of naïve T cell in the islets may contribute to epitope spreading. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 article

Immunogenicity of Lactobacillus gasseri-FliC as an oral mucosal vaccine adjuvant for HIV

RETROVIROLOGY, Vol. 6.

By: S. Gunderson n, S. Nordone n, A. LaVoy n, L. Zhang n, T. Klaenhammer n & G. Dean n

TL;DR: The immunogenicity of a novel Lactobacillus gasseri mucosal vaccine vector for use in oral delivery of HIV antigens is investigated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Free energy calculation of modified base-pair formation in explicit solvent: A predictive model

RNA, 15(12), 2278–2287.

By: F. Vendeix n, A. Munoz n & P. Agris n

author keywords: modified nucleosides; base pairs in water; wobble recognition; refined molecular dynamics simulation
MeSH headings : Base Pairing; Models, Genetic; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; RNA / chemistry; Thermodynamics
TL;DR: MDS is predictive of the effects of modifications, H(2)O molecule intervention in the formation of base-pair geometry, and energies that are important for native RNA structure and function. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Expression of cyclooxygenase-1 and -2 in the left dorsal colon after different durations of ischemia and reperfusion in horses

American Journal of Veterinary Research, 70(12), 1536–1544.

By: A. Morton n, A. Grosche n, A. Rötting n, S. Matyjaszek n, A. Blikslager n & D. Freeman n

Contributors: A. Morton n, A. Grosche n, A. Rötting n, S. Matyjaszek n, A. Blikslager n & D. Freeman n

MeSH headings : Animals; Colitis, Ischemic / veterinary; Colon / blood supply; Colon / metabolism; Colon / pathology; Cyclooxygenase 1 / genetics; Cyclooxygenase 1 / metabolism; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Gene Expression Regulation, Enzymologic; Horse Diseases / metabolism; Horse Diseases / pathology; Horses; Reperfusion Injury / metabolism; Reperfusion Injury / veterinary; Time Factors
TL;DR: It is suggested that upregulation of COX-2 in surface epithelium and crypt cells following ischemic injury in equine colon may represent an early step in the repair process. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Evaluating Placental Transfer and Tissue Concentrations of Manganese in the Pregnant Rat and Fetuses after Inhalation Exposures with a PBPK Model

TOXICOLOGICAL SCIENCES, 112(1), 44–58.

By: M. Yoon*, A. Nong*, H. Clewell*, M. Taylor, D. Dorman n & M. Andersen*

author keywords: manganese; inhalation exposure; gestation; placental transfer; homeostasis during gestation; PBPK
MeSH headings : Animals; Female; Fetus / metabolism; Homeostasis; Inhalation Exposure; Manganese / administration & dosage; Manganese / pharmacokinetics; Maternal-Fetal Exchange; Placenta / metabolism; Pregnancy; Rats; Rats, Wistar; Tissue Distribution
TL;DR: A PBPK model, based on a published description of manganese (Mn) kinetics in adult rats, has been developed to describe Mn uptake and tissue distribution in the pregnant dam and fetus during dietary and inhalation exposures, and incorporated key physiological processes controlling Mn pharmacokinetics during pregnancy and fetal development. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 review

Canine immunoglobulin E

[Review of ]. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 132(1), 7–12.

author keywords: Canine; Immunoglobulin E; Disease; Diagnosis; Comparative
MeSH headings : Animals; B-Lymphocytes / immunology; B-Lymphocytes / metabolism; Dendritic Cells / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / therapy; Dogs; Humans; Hypersensitivity / blood; Hypersensitivity / immunology; Hypersensitivity / therapy; Hypersensitivity / veterinary; Immunoglobulin E / biosynthesis; Immunoglobulin E / blood; Immunoglobulin E / genetics; Immunoglobulin E / immunology; Immunotherapy
TL;DR: It is clear that research on IgE in spontaneously allergic dogs offers many opportunities to explore novel immunotherapeutic approaches to the control of allergic disease that will benefit both dogs and humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Animal models of autism spectrum disorders: Information for neurotoxicologists

Halladay, A. K., Amaral, D., Aschner, M., Bolivar, V. J., Bowman, A., DiCicco-Bloom, E., … Threadgill, D. W. (2009, September). NEUROTOXICOLOGY, Vol. 30, pp. 811–821.

By: A. Halladay, D. Amaral, M. Aschner, V. Bolivar, A. Bowman, E. DiCicco-Bloom, S. Hyman, F. Keller ...

author keywords: Animal models; Autism; Neurotoxicology; Symposium
MeSH headings : Animals; Child; Child Development Disorders, Pervasive / chemically induced; Child Development Disorders, Pervasive / genetics; Child Development Disorders, Pervasive / physiopathology; Child, Preschool; Disease Models, Animal; Drosophila melanogaster; Environment; Genetic Predisposition to Disease; Humans; Mice; Neurotoxicity Syndromes / complications; Toxicology
TL;DR: The aim of the symposium was to provide researchers with up-to-date information on both the genetics of autism and how they are used in differing in vivo and in vitro animal models as well as to provide a background on the environmental exposures being tested on several animal models. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 patent

Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Self-assembled photosynthesis-inspired light harvesting material and solar cells containing the same

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

SURGICAL REPAIR OF SEVERE FLIPPER LACERATIONS IN A LOGGERHEAD, CARETTA CARETTA, AND A KEMP'S RIDLEY, LEPIDOCHELYS KEMPII, SEA TURTLE

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 40(4), 744–751.

By: M. Church n, M. Grafinger, C. Harms*, G. Lewbart*, L. Christian* & J. Beasley

author keywords: Caretta caretta; Kemp's ridley; Lepidochelys kempii; loggerhead; sea turtle
MeSH headings : Animals; Extremities / pathology; Extremities / surgery; Hindlimb / pathology; Hindlimb / surgery; Lacerations / pathology; Lacerations / surgery; Lacerations / veterinary; Turtles / surgery
TL;DR: Limb function was improved and complete amputations were avoided in both turtles and a rotational flap was used to cover exposed tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 patent

Route to formyl-porphyrins

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Nanotube structures having a surfactant bilayer inner wall coating

By: A. Smirnov

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Methods and intermediates for the synthesis of porphyrins

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Levels of house dust mite-specific serum immunoglobulin E (IgE) in different cat populations using a monoclonal based anti-IgE enzyme-linked immunosorbent assay

VETERINARY DERMATOLOGY, 20(5-6), 562–568.

By: J. Bexley, J. Hogg, B. Hammerberg n & R. Halliwell*

MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antigens, Dermatophagoides / immunology; Cat Diseases / immunology; Cats; Dermatitis, Atopic / immunology; Dermatitis, Atopic / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Immunoglobulin E / blood; Male; Pyroglyphidae / immunology
TL;DR: The results suggest that DF in its native form may be a significant allergen in cats with allergic dermatitis, however, the clinical relevance of these reactions remains to be proven. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2009 patent

High density memory device

By: D. Bocian, W. Kuhr, J. Lindsey, P. Clausen & D. Gryko

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Equine immune-mediated keratopathies

Veterinary Ophthalmology, 12, 10–16.

By: A. Matthews* & B. Gilger n

author keywords: cornea; equine; immune-mediated; keratitis; nonulcerative
MeSH headings : Animals; Horse Diseases / immunology; Horse Diseases / pathology; Horses; Keratitis / immunology; Keratitis / pathology; Keratitis / veterinary
TL;DR: The clinical differences in horses with this disease are compared and the current theories on pathogenesis and treatment of equine IMMK are reviewed. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Environmental and Physiological Controls of Blue Crab Avoidance Behavior During Exposure to Hypoxia

BIOLOGICAL BULLETIN, 217(2), 161–172.

By: G. Bell n, D. Eggleston n & E. Noga n

MeSH headings : Animals; Avoidance Learning; Behavior / drug effects; Brachyura / physiology; Hypoxia; Locomotion; Stress, Physiological
TL;DR: Blue crabs that had hemocyanin structures with a high affinity for O2 (hypoxia-tolerant) were less active under hypoxic conditions than conspecifics with hemOCyanins with a low O2 affinity, suggesting that physiological state influences behavioral responses to stressors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

GENES & DEVELOPMENT, 23(21), 2521–2536.

By: S. Munger, D. Aylor, H. Syed, P. Magwene, D. Threadgill* & B. Capel

author keywords: Sex determination; genetical genomics; systems genetics; eQTL; transcription networks; organogenesis
MeSH headings : Animals; Breeding; Cluster Analysis; Disorders of Sex Development; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic Variation; Gonads / metabolism; Male; Mice; Mice, Inbred C57BL; Quantitative Trait Loci / genetics; SOX9 Transcription Factor / metabolism; Sex Determination Processes; X Chromosome / genetics; Y Chromosome / genetics
TL;DR: The results reveal the complex transcription architecture underlying sex determination, and provide a mechanism by which individuals may be sensitized for sex reversal, and estimated the F2 coexpression network and predicted roles for genes of unknown function based on their connectivity and position within the network. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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