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Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 journal article

Third generation impedimetric sensor employing direct electron transfer type glucose dehydrogenase

BIOSENSORS & BIOELECTRONICS, 129, 189–197.

By: Y. Ito*, J. Okuda-Shimazaki  n, W. Tsugawa *, N. Loew n, I. Shitanda *, C. Lin*, J. La Belle *, K. Sode n 

co-author countries: Japan 🇯🇵
author keywords: Faradaic electrochemical impedance spectroscopy; Impedimetric biosensor; Direct electron transfer; FAD dependent glucose dehydrogenase complex; Charge transfer resistance; Imaginary impedance monitoring
MeSH headings : Bacteria / enzymology; Biosensing Techniques / methods; Electric Impedance; Electrodes; Electron Transport; Flavin-Adenine Dinucleotide / chemistry; Glucose / analysis; Glucose 1-Dehydrogenase / chemistry; Gold / chemistry
topics (OpenAlex): Electrochemical sensors and biosensors; Advanced biosensing and bioanalysis techniques; Electrochemical Analysis and Applications
TL;DR: The 3rd-generation faradaic enzyme EIS sensor would provide alternative platform for future impedimetric immunosensing system, which does not use redox probe, according to its potential application as the future immunosensor platform. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 11, 2019

2010 journal article

Expression of IL-4/IL-13 receptors in differentiating human airway epithelial cells

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 299(5), L681–L693.

By: S. White *, L. Martin n, R. Stern*, B. Laxman* & B. Marroquin*

author keywords: interleukin-4; interleukin-13; eotaxin-3; migration
MeSH headings : Animals; Cell Differentiation / physiology; Cell Movement; Cells, Cultured; Chemokine CCL26; Chemokines, CC / genetics; Chemokines, CC / metabolism; Epithelial Cells / cytology; Epithelial Cells / physiology; Humans; Protein Subunits / genetics; Protein Subunits / metabolism; Receptors, Interleukin-13 / genetics; Receptors, Interleukin-13 / metabolism; Receptors, Interleukin-4 / genetics; Receptors, Interleukin-4 / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / physiology; Stress, Mechanical
topics (OpenAlex): Asthma and respiratory diseases; IL-33, ST2, and ILC Pathways; Immune Cell Function and Interaction
TL;DR: Substantial differences in IL-4/IL-13 receptor subunit expression and responsiveness toIL-4 based on the extent of airway epithelial cell differentiation are demonstrated and it is suggested that these differences may have functional consequences in airway inflammation. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2010 journal article

Susceptibility of Inflamed Alveolar and Airway Epithelial Cells to Injury Induced by Diesel Exhaust Particles of Varying Organic Carbon Content

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(8), 565–580.

By: N. Manzo n, R. Slade*, J. Richards*, J. McGee*, L. Martin n & J. Dye *

MeSH headings : Actins / metabolism; Air Pollutants / chemistry; Air Pollutants / toxicity; Animals; Carbon / toxicity; Cells, Cultured; Glutathione / metabolism; Heme Oxygenase-1 / metabolism; L-Lactate Dehydrogenase / metabolism; Mice; Particulate Matter / chemistry; Particulate Matter / toxicity; Pulmonary Alveoli / drug effects; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Vehicle Emissions / toxicity
topics (OpenAlex): Air Quality and Health Impacts; Energy and Environment Impacts; Air Quality Monitoring and Forecasting
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Source: Web Of Science
Added: August 6, 2018

2009 journal article

Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 297(1), L164–L173.

By: S. White *, L. Martin*, M. Abe, B. Marroquin, R. Stern & X. Fu*

author keywords: epithelium; interleukin-4; STAT6; IRS-1; IRS-2
MeSH headings : Air; Cell Differentiation / drug effects; Cell Line; Cell Movement / drug effects; DNA, Complementary / genetics; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Genes, Dominant; Humans; Insulin Receptor Substrate Proteins / metabolism; Interleukin-4 / pharmacology; Lung / cytology; Lung / pathology; Phosphorylation / drug effects; RNA, Small Interfering / metabolism; STAT6 Transcription Factor / metabolism
topics (OpenAlex): Neonatal Respiratory Health Research; Immune Response and Inflammation; IL-33, ST2, and ILC Pathways
TL;DR: It is demonstrated that IL-4 can accelerate migration of differentiated AEC after injury, and this reparative response does not require STAT6 activation, but rather requires IRS-1 and/or IRS-2. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17

Respiratory Research, 8.

By: B. Booth, T. Sandifer, E. Martin & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2007 patent

Method and compositions for altering mucus secretion

Washington, DC: U.S. Patent and Trademark Office.

By: Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Analysis of institutionally specific retention research: A comparison between survey and institutional database methods

RESEARCH IN HIGHER EDUCATION, 48(4), 435–451.

By: A. Caison n

co-author countries: Canada 🇨🇦
author keywords: retention; methodology; survey research; information theory; model selection
topics (OpenAlex): Higher Education Research Studies; Evaluation of Teaching Practices
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4. Quality Education (Web of Science)
10. Reduced Inequalities (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro

Respiratory Research, 7, 35.

By: B. Chorley, A. Crews, Y. Li, K. Adler, M. Minnicozzi & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Methods for regulating inflammatory mediators and peptides useful therein

Washington, DC: U.S. Patent and Trademark Office.

By: S. Takashi, I. Parikh, K. Adler, L. Martin & L. Y.

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Pulmonary lesions in cats with diabetes mellitus

JOURNAL OF VETERINARY INTERNAL MEDICINE, 20(1), 47–51.

By: A. Mexas n, R. Hess *, E. Hawkins n  & L. Martin n

author keywords: complications of diabetes mellitus; feline; lung histopathology
topics (OpenAlex): Diabetes and associated disorders; Fibroblast Growth Factor Research; Advanced Glycation End Products research
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 patent

Culture system for mouse tracheal epithelial cells

Washington, DC: U.S. Patent and Trademark Office.

By: L. Martin, K. Adler, M. Macchione, N. Akley & S. McKane

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

ErbB2 activity is required for airway epithelial repair following neutrophil elastase exposure

FASEB Journal, 19(7).

By: B. Fischer, J. Cuellar, A. Byrd, A. Rice, J. Bonner, L. Martin, J. Voynow

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism

AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651–661.

By: J. Park n, F. He n, L. Martin n, Y. Li n, B. Chorley n & K. Adler n

MeSH headings : Bronchi / cytology; Bronchi / drug effects; Bronchi / metabolism; Cell Differentiation; Cells, Cultured; Enzyme Activation / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Isoenzymes / metabolism; Leukocyte Elastase / pharmacology; Mucins / metabolism; Protein Kinase C / metabolism; Protein Kinase C / physiology; Protein Kinase C-delta; Protein Kinase Inhibitors / pharmacology
topics (OpenAlex): Neonatal Respiratory Health Research; Cystic Fibrosis Research Advances; Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
TL;DR: The results suggest HNE stimulation of mucin release by human airway epithelial cells involves intracellular activation of PKC, specifically the delta isoform. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 journal article

Modeling the airway epithelium in allergic asthma: Interleukin-13-induced effects in differentiated murine tracheal epithelial cells

In Vitro Cellular & Developmental Biology. Animal, 41(7), 217–224.

By: S. Lankford, M. Macchione, A. Crews, S. McKane, N. Akley & L. Martin

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Viability of glycerol-preserved and cryopreserved anuran skin

In Vitro Cellular & Developmental Biology. Animal, 41(09-Aug), 258–263.

By: S. Willens, M. Stoskopf, L. Martin & G. Lewbart 

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma

NATURE MEDICINE, 10(2), 193–196.

By: M. Singer*, L. Martin n, B. Vargaftig*, J. Park n, A. Gruber, Y. Li n, K. Adler n

co-author countries: Brazil 🇧🇷 France 🇫🇷
MeSH headings : Animals; Asthma / metabolism; Bronchi / cytology; Bronchi / metabolism; Bronchi / pathology; Bronchial Provocation Tests; Cytoplasmic Granules / metabolism; Cytoplasmic Granules / ultrastructure; Disease Models, Animal; Humans; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mucins / metabolism; Mucus / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Ovalbumin / administration & dosage; Ovalbumin / immunology; Peptide Fragments / administration & dosage; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Peptides / administration & dosage; Peptides / chemistry; Peptides / pharmacology; Proteins / chemistry; Proteins / genetics; Proteins / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / metabolism
topics (OpenAlex): Neonatal Respiratory Health Research; Cystic Fibrosis Research Advances; Asthma and respiratory diseases
TL;DR: It is shown that the intratracheal instillation of this peptide blocks mucus hypersecretion in a mouse model of asthma, and a pivotal role for MARCKS protein, specifically its N-terminal region, in modulating this secretory process in mammalian airways is supported. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 patent

Blocking peptide for inflammatory cell secretion

Washington, DC: U.S. Patent and Trademark Office.

By: L. Martin, K. Adler & Y. Li

Source: NC State University Libraries
Added: August 6, 2018

2004 review

Eisenbower's atoms for peace

[Review of ]. Historian, 66(3), 577–578.

By: C. Pruden

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 171(4), 305–314.

By: H. Deshmukh  n, L. Case n, S. Wesselkamper n, M. Borchers  n, L. Martin n, H. Shertzer n, J. Nadel n, G. Leikauf  n

author keywords: bronchitis; emphysema; human bronchial epithelial cells; mucin
MeSH headings : Acrolein / pharmacology; Blotting, Western; Cells, Cultured; ErbB Receptors / drug effects; ErbB Receptors / metabolism; Glutathione / metabolism; Humans; Metalloproteases / metabolism; Mitogen-Activated Protein Kinases / metabolism; Mucin 5AC; Mucins / drug effects; Mucins / genetics; Mucins / metabolism; Oxidative Stress / physiology; Polymerase Chain Reaction / methods; RNA, Messenger / biosynthesis; RNA, Messenger / drug effects; Up-Regulation / drug effects
topics (OpenAlex): Protease and Inhibitor Mechanisms; Peptidase Inhibition and Analysis; Antifungal resistance and susceptibility
TL;DR: Together, data suggest that acrolein induces MUC5AC expression via an initial ligand-dependent activation of EGFR mediated by ADAM17 and MMP9 and TIMP3 transcription, and that a prolonged effect of acrole in NCI-H292 cells may be mediated by altering MMP 9 and TIMp3 transcription. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 article

A myristoylated peptide directed against the N-terminal region of MARCKS protein inhibits mucin secretion in ovalbumin sensitized/challenged mice in vivo.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A17.

By: B. Vargaftig, M. Singer, L. Martin, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Differential effects of albuterol isomers on normal human bronchial epithelial cells in vitro.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A205.

By: B. Chorley, L. Martin, A. Crews, Y. Li & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Effects of TNF alpha on expression of ICAM-1 in human airway epithelial cells in vitro: Oxidant-mediated pathways and transcription factors

FREE RADICAL BIOLOGY AND MEDICINE, 35(9), 1158–1167.

By: T. Krunkosky n, L. Martin n, B. Fischer  n, J. Voynow * & K. Adler n

author keywords: intercellular adhesion molecule 1; normal human bronchial epithelial cells; nuclear factor kappa beta; CAAT/enhancer binding protein; free radicals
MeSH headings : Antioxidants / pharmacology; Antioxidants / toxicity; Bronchi / cytology; CCAAT-Enhancer-Binding Proteins / metabolism; Cell Line; Consensus Sequence / genetics; Cysteine Endopeptidases / metabolism; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Gene Expression Regulation / drug effects; Humans; Intercellular Adhesion Molecule-1 / genetics; Leupeptins / pharmacology; Multienzyme Complexes / antagonists & inhibitors; Multienzyme Complexes / metabolism; NF-kappa B / metabolism; Oxidants / metabolism; Promoter Regions, Genetic / genetics; Proteasome Endopeptidase Complex; Pyrrolidines / pharmacology; Pyrrolidines / toxicity; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reactive Oxygen Species / metabolism; Response Elements / genetics; Signal Transduction / drug effects; Thiocarbamates / pharmacology; Thiocarbamates / toxicity; Thiourea / analogs & derivatives; Thiourea / pharmacology; Thiourea / toxicity; Transcription Factors / metabolism; Tumor Necrosis Factor-alpha / pharmacology
topics (OpenAlex): Immune Response and Inflammation; Inflammatory mediators and NSAID effects
TL;DR: Results suggest that although TNFα enhances binding of C/EBP and NFκB complexes in NHBE cells, C-EBP binding seems to involve an oxidant-dependent mechanism, whereas activation of NFκBs complexes utilizes the ubiquitin-proteasome pathway, a mechanism that seems to be unaltered by the presence of antioxidants. (via Semantic Scholar)
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14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2003 article

Human neutrophil elastase provokes release of MUC5B mucin from normal bronchial epithelial cells in vitro via a PKC-dependent mechanism.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A203.

By: J. Park, F. He, Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

PI3K signaling is required for prostaglandin-induced mucosal recovery in ischemia-injured porcine ileum

American Journal of Physiology-Gastrointestinal and Liver Physiology, 284(1), G46–G56.

By: D. Little*, R. Dean, K. Young*, S. McKane n, L. Martin n, S. Jones* , A. Blikslager* 

author keywords: phosphatidylinositol 3-kinase; tight junction; occludin; zonula occludens-1
MeSH headings : 16,16-Dimethylprostaglandin E2 / pharmacology; Animals; Anti-Ulcer Agents / pharmacology; Electric Impedance; Epoprostenol / analogs & derivatives; Epoprostenol / pharmacology; Female; Humans; Ileum / metabolism; Intestinal Mucosa / enzymology; Intestinal Mucosa / ultrastructure; Ischemia / metabolism; Male; Membrane Proteins / metabolism; Microscopy, Electron; Occludin; Osmotic Pressure; Phosphatidylinositol 3-Kinases / metabolism; Phosphoproteins / metabolism; Platelet Aggregation Inhibitors / pharmacology; Recovery of Function / physiology; Signal Transduction / drug effects; Signal Transduction / physiology; Swine; Tight Junctions / enzymology; Urea / pharmacology; Zonula Occludens-1 Protein
topics (OpenAlex): Barrier Structure and Function Studies; Drug Transport and Resistance Mechanisms; Connexins and lens biology
TL;DR: These experiments suggest that PGs stimulate recovery of paracellular resistance via a mechanism involving transepithelial osmotic gradients and PI3K-dependent restoration of tight junction protein distribution. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2003 article

Proliferation of the airway epithelium in asthma - Are inflammatory cells required?

Booth, B. W., Newcomb, D. C., McKane, S. A., Crews, A. L., Adler, K. B., Bonner, J. C., & Martin, L. D. (2003, March). CHEST, Vol. 123, pp. 384S–385S.

By: B. Booth  n, D. Newcomb  n, S. McKane n, A. Crews n, K. Adler n, J. Bonner *, L. Martin n

MeSH headings : Asthma / pathology; Asthma / physiopathology; Cell Physiological Phenomena; Humans; In Vitro Techniques; Inflammation / pathology; Inflammation / physiopathology; Respiratory Mucosa / pathology; Respiratory Mucosa / physiopathology
topics (OpenAlex): Asthma and respiratory diseases; Cancer-related gene regulation
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Source: Web Of Science
Added: August 6, 2018

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