Works Published in 2019
Displaying works 21 - 40 of 227 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 article
How to make more from exposure data? An integrated machine learning pipeline to predict pathogen exposure
BioRxiv.
Contributors: N. Fountain-Jones *, G. Machado n , S. Carver *, C. Packer *, M. Recamonde-Mendoza * & M. Craft*
TL;DR:
This approach compares multiple machine learning algorithms in a unified environment to find the model with the best predictive performance and uses game theory to better interpret results, and applies this framework on two major pathogens that infect African lions: canine distemper virus and feline parvovirus.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
Source: ORCID
Added: November 27, 2021
2019 journal article
Health benefits of subcutaneous zinc edetate and diphenyl diselenide in calves during the weaning period
Anais Da Academia Brasileira De Ciencias, 91(1).
Contributors: D. Dos Santos *, J. Boito*, V. Klauck *, J. Dos Reis, R. Gebert*, P. Glombowsky*, A. Biazus*, N. Bottari*
author keywords: calves; zinc edetate; (PhSe)(2); animal health
MeSH headings : Age Factors; Animals; Antioxidants / analysis; Benzene Derivatives / administration & dosage; Body Weight; Cattle / physiology; Edetic Acid / administration & dosage; Immune System / drug effects; Injections, Subcutaneous / veterinary; Lipid Metabolism / drug effects; Malondialdehyde / blood; Muscles / metabolism; Organoselenium Compounds / administration & dosage; Proteins / metabolism; Reproducibility of Results; Selenium / administration & dosage; Time Factors; Weaning; Zinc / administration & dosage
TL;DR:
One of the principal findings was that (PhSe)2+Zn together had beneficial effects on protein metabolism, represented by increases total protein and globulin levels, compared with the control group.
(via Semantic Scholar)
Source: ORCID
Added: November 27, 2021
2019 conference paper
Prevalence and antimicrobial susceptibility of salmonella and e. coli in sheep and environment in North Carolina – an abattoir-based study
Atlaw, N. A. (2019, August 16). Presented at the Annual College of Veterinary Medicine (CVM) Research Forum, Raleigh, North Carolina, USA.
Event: Annual College of Veterinary Medicine (CVM) Research Forum at Raleigh, North Carolina, USA on August 16, 2019
Source: NC State University Libraries
Added: November 16, 2021
2019 conference paper
Prevalence and antimicrobial susceptibility of Salmonella and E. coli in sheep and environment in North Carolina
Proceedings for the 100th Annual Conference of Research Workers in Animal Diseases. Presented at the 100th Annual Conference of Research Workers in Animal Diseases, Chicago, Illinois.
Event: 100th Annual Conference of Research Workers in Animal Diseases at Chicago, Illinois on November 2-5, 2019
Source: NC State University Libraries
Added: November 16, 2021
2019 conference paper
Assessing delivery efficiency of nanoparticles to tumors in tumor-bearing mice using a physiologically based pharmacokinetic modeling and simulation approach
The Toxicologist, 168(1), 476–477,
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
Source: NC State University Libraries
Added: August 13, 2021
2019 conference paper
Integration of Food Animal Residue Avoidance Databank (FARAD) Empirical Methods for Drug Withdrawal Interval Determination with a Mechanistic Population-Based Interactive Physiologically Based Pharmacokinetic (iPBPK) Modeling Platform: Example for Flunixin Meglumine Administration
The Toxicologist, 168(1), 191.
Event: 58th Society of Toxicology annual meeting & ToxExpo at Baltimore, Maryland on March 10-14, 2019
Source: NC State University Libraries
Added: August 13, 2021
2019 journal article
An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows
Journal of Veterinary Pharmacology and Therapeutics, 42(4), 461–475.
author keywords: extralabel withdrawal interval; food safety; heavy sow; physiologically based pharmacokinetic (PBPK) model; procaine penicillin G (PPG); tissue residue
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Body Weight; Computer Simulation; Dose-Response Relationship, Drug; Drug Residues; Female; Models, Biological; Penicillin G / administration & dosage; Penicillin G / pharmacokinetics; Swine / blood; Swine / metabolism; Swine / urine
TL;DR:
The results showed that antemortem testing of urine provided potential correlation with tissue residue levels and provided a tool to predict proper withdrawal intervals after extralabel use of penicillin G in heavy sows, thereby helping safety assessment of sow-derived meat products.
(via Semantic Scholar)
Source: Crossref
Added: August 13, 2021
2019 journal article
Extralabel drug use in wildlife and game animals
Journal of the American Veterinary Medical Association, 255(5), 555–568.
MeSH headings : Animals; Animals, Wild; Off-Label Use / veterinary
TL;DR:
Wildlife or game animals will refer to free-ranging nondomesticated mammals, reptiles, and bird species as well as animals that are confined or farm raised and subsequently hunted for personal consumption or slaughtered for commercial purposes and thus are considered food-producing animals.
(via Semantic Scholar)
Source: Crossref
Added: August 13, 2021
2019 journal article
Novel Data Sharing Agreement to Accelerate Big Data Translational Research Projects in the One Health Sphere
Topics in Companion Animal Medicine, 37, 100367.
author keywords: data sharing; one health; public-private partnership; data analysis; legal issues; translational research; big data
MeSH headings : Animals; Big Data; Data Anonymization; Health Insurance Portability and Accountability Act; Humans; Information Dissemination / methods; One Health; Translational Research, Biomedical / organization & administration; United States
TL;DR:
The 1DATA Project examined and overcome some of the barriers to sharing data generated by researchers and clinicians working with for-profit companies, and the ways those obstacles can be surmounted via a novel form of Master Sharing Agreement are discussed.
(via Semantic Scholar)
Source: Crossref
Added: August 13, 2021
2019 journal article
Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats
Topics in Companion Animal Medicine, 37, 100366.
author keywords: similarity association; drug adverse events; artificial intelligence; pharmacovigilance machine learning algorithms; graphical LASSO; companion animals
MeSH headings : Algorithms; Animals; Artificial Intelligence; Cats; Dogs; Drug Combinations; Drug-Related Side Effects and Adverse Reactions / veterinary; Ivermectin / adverse effects; Ivermectin / analogs & derivatives; Machine Learning; Macrolides / adverse effects; Pharmacovigilance
TL;DR:
A comparative analysis of ADEs based on an artificial intelligence (AI) approach for the 5 robust similarity methods revealed high ADE associations for 2 drugs used in dogs and cats, and showed that the cosine method significantly outperformed all the other methods by correctly detecting and validating ADEs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 13, 2021
2019 report
Pharmaceutical quality strontium L-lactate
(Patent No. US10463636B2).
Source: NC State University Libraries
Added: July 27, 2021
2019 journal article
Oyster Mariculture in Puerto Rico- A Preliminary Evaluation of Methods and Feasibility
World Aquaculture, 50, 39–44.
Source: NC State University Libraries
Added: April 24, 2021
2019 book
Science Breakthroughs to Advance Food and Agricultural Research by 2030
In SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030 (pp. 1–228).
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: November 24, 2020
2019 journal article
Cancer‐testis antigens in canine histiocytic sarcoma and other malignancies
Veterinary and Comparative Oncology, 17(3), 317–328.
author keywords: cancer-testis antigens; dog; histiocytic sarcoma; mass spectrometry; MHC class I
MeSH headings : Animals; Antigens, Neoplasm / metabolism; Cell Line, Tumor; Chromatography, Liquid; Dog Diseases / metabolism; Dogs; Gene Expression Regulation, Neoplastic / physiology; HLA Antigens / metabolism; Histiocytic Sarcoma / genetics; Histiocytic Sarcoma / metabolism; Humans; Male; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tandem Mass Spectrometry; Testis / metabolism
TL;DR:
The results illustrate the feasibility of discovering canine CTAs by a reverse approach, proceeding from identification of MHC class I-presented peptides to a comparative RNA expression survey of tumours and normal tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 7, 2020
2019 journal article
Prevalence and risk factors for multi-drug resistant Escherichia coli among poultry workers in the Federal Capital Territory, Abuja, Nigeria
PLOS ONE, 14(11), e0225379.
Ed(s): G. Woźniakowski
MeSH headings : Adolescent; Adult; Animals; Cross-Sectional Studies; Escherichia coli / drug effects; Escherichia coli Infections / epidemiology; Escherichia coli Infections / microbiology; Female; Humans; Male; Nigeria / epidemiology; Poultry Diseases / epidemiology; Prevalence; Risk Factors; Surveys and Questionnaires; Young Adult
TL;DR:
Prevalence of resistant E. coli was highest among farm-workers and associated with older farms/markets, occupational exposure of over 10 years and poor hygienic measures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: June 8, 2020
2019 journal article
Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth
PLOS ONE, 14(10).
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Knee Joint / diagnostic imaging; Knee Joint / growth & development; Magnetic Resonance Imaging; Organ Specificity; Patellar Ligament / diagnostic imaging; Patellar Ligament / growth & development; Swine
TL;DR:
The findings suggest that musculoskeletal soft tissue morphometry can vary within tissues of similar structure and within a single joint during post-natal growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: June 8, 2020
2019 journal article
Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
PLOS ONE, 14(10).
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacokinetics; Cattle; Cattle Diseases / drug therapy; Cattle Diseases / microbiology; Cephalosporins / administration & dosage; Cephalosporins / chemistry; Cephalosporins / pharmacokinetics; Drug Resistance, Bacterial; Escherichia coli / classification; Escherichia coli / drug effects; Escherichia coli / genetics; Feces / microbiology; Microbial Sensitivity Tests; Microbiota; RNA, Ribosomal, 16S / genetics
TL;DR:
CCFA leads to prolonged, low intestinal drug concentrations, and is associated with decreased E. coli concentration, an increased MIC of ceftiofur in E. Escherichia coli at specific time points, and shifts in the fecal microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020
2019 article
Bacterial Diversity in Feces of Wild Bald Eagles, Turkey Vultures and Common Ravens from the Pacific Northwest Coast, U.S.A
Crespo, R., Dowd, S. E., Varland, D. E., Ford, S., & Hamer, T. E. (2019, January 3). BioRxiv, Vol. 1.
Contributors: R. Crespo* , S. Dowd*, D. Varland, S. Ford & T. Hamer
TL;DR:
This investigation revealed phylum-level differences in the microbiome of turkey vultures, compared with bald eagles and common ravens, which provides the first integrated look at the composition of the avian microbiota and serves as a foundation for future studies in this area.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: April 26, 2020
2019 journal article
Mast cell corticotropin-releasing factor subtype 2 suppresses mast cell degranulation and limits the severity of anaphylaxis and stress-induced intestinal permeability
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 143(5), 1865-+.
author keywords: Mast cell; corticotropin-releasing factor receptor; stress; anaphylaxis; allergy; intestinal permeability
MeSH headings : Anaphylaxis / immunology; Animals; Cell Degranulation; Cell Line; Disease Models, Animal; Female; Histamine Release / genetics; Humans; Immunoglobulin E / metabolism; Intestinal Mucosa / metabolism; Mast Cells / physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Receptors, Corticotropin-Releasing Hormone / genetics; Receptors, Corticotropin-Releasing Hormone / metabolism; Stress, Psychological / immunology; Tight Junctions / metabolism
TL;DR:
MC CRF2 is a negative global modulator of stimuli‐induced MC degranulation and limits the severity of IgE‐mediated anaphylaxis and stress‐related disease pathogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: April 20, 2020
2019 journal article
Use of Commercial Swine Live Attenuated Vaccine to Control an Erysipelothrix rhusiopathiae Outbreak in Commercial Cage-Free Layer Chickens
AVIAN DISEASES, 63(3), 520–524.
Contributors: R. Crespo* , M. Bland & T. Opriessnig *
author keywords: attenuated vaccine; chicken; drag swab; drinking water; environment; Erysipelothrix rhusiopathiae; vaccination
MeSH headings : Animals; Bacterial Vaccines / immunology; Chickens; Disease Outbreaks / prevention & control; Disease Outbreaks / veterinary; Erysipelothrix / immunology; Erysipelothrix Infections / prevention & control; Female; Poultry Diseases / prevention & control; Sus scrofa; Vaccination / veterinary; Vaccines, Attenuated / immunology
TL;DR:
This is the first report describing the use of an attenuated vaccine to control an E. rhusiopathiae outbreak in a chicken flock and Bacitracin administered via the water reduced mortality minimally and only for a short period of time.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 20, 2020
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