Works (38)

2020 review

Diversification of host bile acids by members of the gut microbiota

[Review of ]. GUT MICROBES, 11(2), 158–171.

By: J. Winston & C. Theriot

Source: Web Of Science
Added: March 30, 2020

2020 journal article

Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(12), 6792–6800.

By: J. Tam, S. Icho, E. Utama, K. Orrell, R. Gomez-Biagi, C. Theriot, H. Kroh, S. Rutherford, D. Lacy, R. Melnyk

Source: Web Of Science
Added: April 14, 2020

2020 article

Role of Microbiota-Derived Bile Acids in Enteric Infections

CELL, Vol. 181, pp. 1452–1454.

By: C. Theriot & W. Petri

Source: Web Of Science
Added: July 20, 2020

2020 journal article

Salicylanilide Analog Minimizes Relapse of Clostridioides difficile Infection in Mice

JOURNAL OF MEDICINAL CHEMISTRY, 63(13), 6898–6908.

By: S. Blake, R. Thanissery, A. Rivera, M. Hixon, M. Lin, C. Theriot, K. Janda

Source: Web Of Science
Added: August 10, 2020

2020 journal article

Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids

INFECTION AND IMMUNITY, 88(6).

By: J. Winston, A. Rivera, J. Cai, R. Thanissery, S. Montgomery, A. Patterson, C. Theriot

Source: Web Of Science
Added: June 15, 2020

2019 journal article

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

PLOS PATHOGENS, 15(3).

By: M. Foley, S. O'Flaherty, R. Barrangou & C. Theriot

Source: Web Of Science
Added: April 15, 2019

2019 journal article

Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers

PLOS ONE, 14(10).

By: D. Foster, M. Jacob, K. Farmer, B. Callahan, C. Theriot, S. Kathariou, N. Cernicchiaro, T. Prange, M. Papich

Source: Web Of Science
Added: June 1, 2020

2019 article

Human fecal metabolomic profiling could inform Clostridioides difficile infection diagnosis and treatment

JOURNAL OF CLINICAL INVESTIGATION, Vol. 129, pp. 3539–3541.

By: C. Theriot & J. Fletcher

Source: Web Of Science
Added: September 30, 2019

2018 journal article

A small molecule-screening pipeline to evaluate the therapeutic potential of 2-aminoimidazole molecules against clostridium difficile

Frontiers in Microbiology, 9.

By: R. Thanissery, D. Zeng, R. Doyle & C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Beyond structure: Defining the function of the gut using omic approaches for rational design of personalized therapeutics

Msystems, 3(2).

By: C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers

FRONTIERS IN MICROBIOLOGY, 9.

By: K. Ferguson, M. Jacob, C. Theriot, B. Callahan, T. Prange, M. Papich, D. Foster

Source: NC State University Libraries
Added: October 16, 2018

2018 journal article

MICROBIOME Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells

Science, 360(6391), 876-.

By: C. Ma, M. Han, B. Heinrich, Q. Fu, Q. Zhang, M. Sandhu, D. Agdashian, M. Terabe ...

Source: NC State University Libraries
Added: August 6, 2018

2018 conference paper

Restoration of short chain fatty acid and bile acid metabolism following fecal microbiota transplantation in patients with recurrent Clostridium difficile infection

ANAEROBE, 53, 64–73.

By: A. Seekatz, C. Theriot, K. Rao, Y. Chang, A. Freeman, J. Kao, V. Young

Source: NC State University Libraries
Added: November 26, 2018

2018 journal article

Shifts in the gut metabolome and Clostridium difficile transcriptome throughout colonization and infection in a mouse model

Msphere, 3(2).

By: J. Fletcher, S. Erwin, C. Lanzas & C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

The lactobacillus bile salt hydrolase repertoire reveals niche-specific adaptation

Msphere, 3(3).

By: S. O'Flaherty, A. Crawley, C. Theriot & R. Barrangou

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Inhibition of spore germination, growth, and toxin activity of clinically relevant C-difficile strains by gut microbiota derived secondary bile acids

Anaerobe, 45, 86–100.

By: R. Thanissery, J. Winston & C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Introduction to the special issue highlighting Anaerobe 2016

Anaerobe, 45, 1–2.

By: L. Cox, C. Theriot & R. Fichorova

Source: NC State University Libraries
Added: August 6, 2018

2017 chapter

Mathematical Modeling of the Effects of Nutrient Competition and Bile Acid Metabolism by the Gut Microbiota on Colonization Resistance Against Clostridium difficile

In Association for Women in Mathematics Series (pp. 137–161).

By: A. Fleming-Davies, S. Jabbari, S. Robertson, T. Asih, C. Lanzas, S. Lenhart, C. Theriot

Source: Crossref
Added: February 21, 2020

2016 journal article

Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine

MSphere, 1(1).

By: C. Theriot, A. Bowman & V. Young

Ed(s): C. Ellermeier

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Cefoperazone-treated mouse model of clinically-relevant Clostridium difficile strain R20291

Jove-Journal of Visualized Experiments, (118).

By: J. Winston, R. Thanissery, S. Montgomery & C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract

Anaerobe, 41, 44–50.

By: J. Winston & C. Theriot

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation

MSystems, 1(1).

By: C. Noecker, A. Eng, S. Srinivasan, C. Theriot, V. Young, J. Jansson, D. Fredricks, E. Borenstein

Ed(s): L. Sanchez

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease

Infection and Immunity, 83(10), 3838–3846.

By: A. Seekatz, C. Theriot, C. Molloy, K. Wozniak, I. Bergin & V. Young

Ed(s): B. McCormick

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Interactions Between the Gastrointestinal Microbiome and Clostridium difficile

Annual Review of Microbiology, 69(1), 445–461.

By: C. Theriot & V. Young

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice

Immunology, 144(4), 587–597.

By: A. Sadighi Akha, A. McDermott, C. Theriot, P. Carlson, C. Frank, R. McDonald, N. Falkowski, I. Bergin, V. Young, G. Huffnagle

Source: Crossref
Added: September 13, 2019

2014 journal article

Alteration of the Murine Gastrointestinal Microbiota by Tigecycline Leads to Increased Susceptibility to Clostridium difficile Infection

Antimicrobial Agents and Chemotherapy, 58(5), 2767–2774.

By: C. Bassis, C. Theriot & V. Young

Source: Crossref
Added: July 28, 2019

2014 chapter

Antibiotic-Associated Diarrhea

In Encyclopedia of Metagenomics (pp. 1–7).

By: C. Theriot & V. Young

Source: Crossref
Added: July 27, 2019

2014 journal article

Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Nature Communications, 5(1).

By: C. Theriot, M. Koenigsknecht, P. Carlson, G. Hatton, A. Nelson, B. Li, G. Huffnagle, J. Z. Li, V. Young

Source: Crossref
Added: July 28, 2019

2014 journal article

Clostridium difficile-induced colitis in mice is independent of leukotrienes

Anaerobe, 30, 90–98.

By: B. Trindade, C. Theriot, J. Leslie, P. Carlson, I. Bergin, M. Peters-Golden, V. Young, D. Aronoff

Source: Crossref
Added: July 28, 2019

2014 journal article

Dynamics and Establishment of Clostridium difficile Infection in the Murine Gastrointestinal Tract

Infection and Immunity, 83(3), 934–941.

By: M. Koenigsknecht, C. Theriot, I. Bergin, C. Schumacher, P. Schloss & V. Young

Ed(s): B. McCormick

Source: Crossref
Added: July 28, 2019

2014 journal article

Effects of Tigecycline and Vancomycin Administration on Established Clostridium difficile Infection

Antimicrobial Agents and Chemotherapy, 59(3), 1596–1604.

By: C. Theriot, C. Schumacher, C. Bassis, A. Seekatz & V. Young

Source: Crossref
Added: July 27, 2019

2013 journal article

Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response

Immunology, 140(1), 111–122.

By: A. Sadighi Akha, C. Theriot, J. Erb-Downward, A. McDermott, N. Falkowski, H. Tyra, D. Rutkowski, V. Young, G. Huffnagle

Source: Crossref
Added: September 13, 2019

2013 journal article

Microbial and metabolic interactions between the gastrointestinal tract and Clostridium difficile infection

Gut Microbes, 5(1), 86–95.

By: C. Theriot & V. Young

Source: Crossref
Added: September 13, 2019

2013 journal article

The Complete Campylobacter jejuni Transcriptome during Colonization of a Natural Host Determined by RNAseq

PLoS ONE, 8(8), e73586.

By: M. Taveirne, C. Theriot, J. Livny & V. DiRita

Ed(s): D. Rasko

Source: Crossref
Added: July 28, 2019

2010 journal article

Hydrolysis of organophosphorus compounds by microbial enzymes

Applied Microbiology and Biotechnology, 89(1), 35–43.

By: C. Theriot & A. Grunden

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Improving the catalytic activity of hyperthermophilic Pyrococcus prolidases for detoxification of organophosphorus nerve agents over a broad range of temperatures

Applied Microbiology and Biotechnology, 87(5), 1715–1726.

By: C. Theriot, X. Du, S. Tove & A. Grunden

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Characterization of two proline dipeptidases (prolidases) from the hyperthermophilic archaeon Pyrococcus horikoshii

Applied Microbiology and Biotechnology, 86(1), 177–188.

By: C. Theriot, S. Tove & A. Grunden

Sources: NC State University Libraries, Crossref
Added: August 6, 2018

2009 review

biotechnological applications of recombinant microbial prolidases

[Review of ]. Advances in applied microbiology, vol 68, 68, 99-.

By: C. Theriot, S. Tove & A. Grunden

Source: NC State University Libraries
Added: August 6, 2018