Works Published in 2014
Displaying works 161 - 180 of 215 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
Short communication: An in vitro assessment of the antibacterial activity of plant-derived oils
JOURNAL OF DAIRY SCIENCE, 97(9), 5587–5591.
author keywords: mastitis; plant-derived oils; alternative to antibiotics; organic
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Cattle; Female; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / microbiology; Mastitis, Bovine / drug therapy; Mastitis, Bovine / microbiology; Milk / microbiology; Oils, Volatile / pharmacology; Plant Oils / pharmacology; Staphylococcus / drug effects; Staphylococcus aureus / drug effects; Streptococcus / drug effects; Thymus Plant / chemistry
TL;DR:
Only thyme essential oil had consistent antibacterial activity against the 3 mastitis-causing organisms tested in vitro, and further evaluation of physiological effects of thyme oil in various preparations on mammary tissue is recommended to determine potential suitability for mastitis therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice
BIOCHEMICAL PHARMACOLOGY, 89(3), 399–412.
author keywords: Obesity; High-fat diet; Pregnane X receptor; Nuclear receptors; Type 2 diabetes; Females
MeSH headings : Adipose Tissue, White; Animals; Blood Glucose; Cytochrome P-450 CYP3A / genetics; Cytochrome P-450 CYP3A / metabolism; Dietary Fats / adverse effects; Female; Gene Expression Regulation; Glucose Intolerance; Humans; Ion Channels / genetics; Ion Channels / metabolism; Liver; Male; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mice; Mice, Transgenic; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Obesity / drug therapy; Obesity / etiology; Pregnane X Receptor; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Uncoupling Protein 1
TL;DR:
The studies indicate that the hPXR gene promotes obesity and metabolic syndrome by dysregulating lipid and glucose homeostasis while inhibiting UCP1 expression and indicates that the human PXR suppresses the protective role of estrogen in metabolic disorders.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Pro-tumorigenic Effects of Transforming Growth Factor Beta 1 in Canine Osteosarcoma
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(3), 894–904.
author keywords: Bone resorption; Malignant osteolysis; Pleiotropic cytokine; Tumorigenesis
MeSH headings : Animals; Blotting, Western; Bone Neoplasms / physiopathology; Bone Neoplasms / veterinary; Cell Line, Tumor; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Osteosarcoma / physiopathology; Osteosarcoma / veterinary; Pyrazoles / pharmacology; Pyrroles / pharmacology; Signal Transduction / drug effects; Transforming Growth Factor beta1 / biosynthesis; Transforming Growth Factor beta1 / metabolism; Transforming Growth Factor beta1 / physiology; Transforming Growth Factor beta2 / biosynthesis; Transforming Growth Factor beta2 / physiology; Vascular Endothelial Growth Factor A / physiology
TL;DR:
Canine OS cells possess TGF β1 signaling machinery, potentially allowing for the establishment of an autocrine and paracrine pro‐tumorigenic signaling loop, and TGFβ1 inhibitors might impede localized OS progression in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Pharmacokinetics and safety of firocoxib after oral administration of repeated consecutive doses to neonatal foals
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(3), 243–251.
MeSH headings : 4-Butyrolactone / administration & dosage; 4-Butyrolactone / adverse effects; 4-Butyrolactone / analogs & derivatives; 4-Butyrolactone / blood; 4-Butyrolactone / pharmacokinetics; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Drug Administration Schedule; Horses / blood; Horses / metabolism; Sulfones / administration & dosage; Sulfones / adverse effects; Sulfones / blood; Sulfones / pharmacokinetics
TL;DR:
It is demonstrated that firocoxib is absorbed in neonatal foals with no demonstrable adverse effects after repeated doses of 0.1 mg/kg.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Pathology of Articular Cartilage and Synovial Membrane From Elbow Joints With and Without Degenerative Joint Disease in Domestic Cats
VETERINARY PATHOLOGY, 51(5), 968–978.
author keywords: degenerative joint disease; elbow joint; feline; histopathology; medial compartment joint disease; synovial osteochondromatosis
MeSH headings : Animals; Bone and Bones / pathology; Cartilage, Articular / anatomy & histology; Cartilage, Articular / pathology; Cat Diseases / pathology; Cats; Female; Forelimb / anatomy & histology; Forelimb / pathology; Joint Diseases / pathology; Joint Diseases / veterinary; Joints / anatomy & histology; Joints / pathology; Male; Severity of Illness Index; Synovial Membrane / anatomy & histology; Synovial Membrane / pathology
TL;DR:
Lesions observed in these animals are most consistent with synovial osteochondromatosis secondary to degenerative joint disease, but a fragmented medial coronoid process or osteochondritis dissecans does not appear to play a role.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Notes on the Fish Parasite Nitzschia (Monogenoidea: Capsalidae) in North America
NORTHEASTERN NATURALIST, 21(3), N18–N27.
TL;DR:
The taxonomic history of Nitzschia sturionis parasitizing North American Acipenser spp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Marinade with thyme and orange oils reduces Salmonella Enteritidis and Campylobacter coli on inoculated broiler breast fillets and whole wings
POULTRY SCIENCE, 93(5), 1258–1262.
author keywords: thyme oil; orange oil; Salmonella; Campylobacter; marination
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Campylobacter coli / drug effects; Campylobacter coli / growth & development; Campylobacter coli / isolation & purification; Chickens / microbiology; Food Contamination / prevention & control; Food Handling / methods; Meat / microbiology; Pectoralis Muscles / microbiology; Pectoralis Muscles / physiology; Plant Oils / pharmacology; Salmonella enteritidis / drug effects; Salmonella enteritidis / growth & development; Salmonella enteritidis / isolation & purification; Thymus Plant / chemistry; Wings, Animal / microbiology; Wings, Animal / physiology
TL;DR:
Marination with a salt phosphate formulation containing 0.5% TOC successfully reduced Salmonella and Campylobacter numbers on poultry products and reduced cross-contamination between inoculated and uninoculated parts during marination.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Investigating the optimal size of anticancer nanomedicine
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(43), 15344–15349.
author keywords: nanomedicine; size effect; silica nanoparticle; mathematical model; drug delivery
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / therapeutic use; Humans; MCF-7 Cells; Mice, Nude; Nanoconjugates; Nanomedicine; Neoplasm Metastasis; Neoplasms / drug therapy; Particle Size; Silicon Dioxide / chemistry; Tissue Distribution; Xenograft Model Antitumor Assays
TL;DR:
Among the three NCs investigated, the 50-nm NC shows the highest tumor tissue retention integrated over time, which is the collective outcome of deep tumor tissue penetration and efficient cancer cell internalization as well as slow tumor clearance, and thus, the highest efficacy against both primary and metastatic tumors in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Use of altrenogest at weaning in primiparous sows
Journal of Swine Health and Production, 22(3), 134–137.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Septic funiculitis caused by Streptococcus equi subspecies equi infection with associated immune- mediated haemolytic anaemia
EQUINE VETERINARY EDUCATION, 26(5), 227–233.
author keywords: horse; castration; septic funiculitis; immune-mediated haemolytic anaemia; azathioprine
TL;DR:
A 2-year-old Quarter Horse gelding presented for anaemia, icterus, depression and intermittent colic 2 weeks after routine castration and a blood transfusion was required to facilitate general anaesthesia for surgical excision of the septic funiculitis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Endangered amphibians infected with the chytrid fungus Batrachochytrium dendrobatidis in austral temperate wetlands from Argentina
Herpetological Journal, 24(2), 129–133.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Effect of 2 herbal intramammary products on milk quantity and quality compared with conventional and no dry cow therapy
JOURNAL OF DAIRY SCIENCE, 97(6), 3509–3522.
author keywords: dry cow therapy; organic mastitis treatment; alternative to antibiotics
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / veterinary; Bismuth / therapeutic use; Cattle; Diet / veterinary; Dihydrostreptomycin Sulfate / therapeutic use; Drugs, Chinese Herbal / administration & dosage; Female; Food Contamination / prevention & control; Food Microbiology; Food, Organic / microbiology; Lactation; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / microbiology; Mastitis, Bovine / drug therapy; Mastitis, Bovine / microbiology; Milk / microbiology; Penicillins / therapeutic use
TL;DR:
The efficacy of the herbal products was similar to that of conventional therapy, and the herbal Products had no apparent adverse effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Canine hereditary ataxia in Old English Sheepdogs and Gordon Setters is associated with a defect in the autophagy gene encoding RAB24
PLoS Genetics, 10(2).
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Biliary Proliferative Lesions in the Sprague-Dawley Rat: Adverse/Non-adverse
TOXICOLOGIC PATHOLOGY, 42(5), 844–854.
author keywords: rat; biliary; oval cell; adverse; proliferative; bile duct; hyperplasia
MeSH headings : Animals; Bile Duct Neoplasms / pathology; Bile Ducts / cytology; Bile Ducts / metabolism; Bile Ducts / pathology; Biomarkers / metabolism; Cell Proliferation; Female; Hyperplasia / pathology; Male; Rats; Rats, Sprague-Dawley
TL;DR:
Available evidence supports the interpretation that minimal “typical” appearing bile duct hyperplasia limited to the portal triads may be considered non-adverse in the rat and is of little to no concern to humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Silver Nanoparticle Behavior, Uptake, and Toxicity in Caenorhabditis elegans: Effects of Natural Organic Matter
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 48(6), 3486–3495.
MeSH headings : Animals; Benzopyrans / chemistry; Benzopyrans / pharmacology; Caenorhabditis elegans / drug effects; Caenorhabditis elegans / metabolism; Humic Substances; Metal Nanoparticles / toxicity; Rivers; Silver / pharmacokinetics; Silver / toxicity
TL;DR:
Measurement of total tissue silver content indicated that PLFA reduced total organismal uptake of ionic silver, but not of citrate-coated Ag NPs (CIT-Ag NPs), and co-exposure to PLFA resulted in the formation of NOM-Ag NP composites and rescued AgNO3- and CIT- Ag NP-induced cellular damage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Role of Pregnane X Receptor in Obesity and Glucose Homeostasis in Male Mice
JOURNAL OF BIOLOGICAL CHEMISTRY, 289(6), 3244–3261.
author keywords: Diabetes; Metabolic Syndrome; Nuclear Receptors; Obesity; Peroxisome Proliferator-activated Receptor (PPAR)
MeSH headings : Adipose Tissue / metabolism; Adipose Tissue / pathology; Animals; Carnitine O-Palmitoyltransferase / genetics; Carnitine O-Palmitoyltransferase / metabolism; Diabetes Mellitus, Type 2 / genetics; Diabetes Mellitus, Type 2 / metabolism; Diabetes Mellitus, Type 2 / pathology; Female; Glucokinase / genetics; Glucokinase / metabolism; Glucose / genetics; Glucose / metabolism; Hepatomegaly / genetics; Hepatomegaly / metabolism; Hepatomegaly / pathology; Humans; Hyperinsulinism / genetics; Hyperinsulinism / metabolism; Hyperinsulinism / pathology; Liver / metabolism; Liver / pathology; Male; Mice; Mice, Knockout; Obesity / genetics; Obesity / metabolism; Obesity / pathology; PPAR alpha / genetics; PPAR alpha / metabolism; Pregnane X Receptor; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Species Specificity
TL;DR:
Although the mouse PXR promotes HFD-induced obesity, the hPXR mouse carries a genetic predisposition for type 2 diabetes and thus provides a model for exploring the role of human PxR in the metabolic syndrome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Prevalence of Brachyspira hyodysenteriae in sows and suckling piglets
Journal of Swine Health and Production, 22(2), 71–77.
Source: NC State University Libraries
Added: August 6, 2018
2014 journal article
Malignant hypertension and retinopathy in a western lowland gorilla (Gorilla gorilla gorilla)
JOURNAL OF MEDICAL PRIMATOLOGY, 43(4), 276–279.
author keywords: arteriosclerosis; hypertensive encephalopathy; necrotizing arteriolitis; retinal detachment
MeSH headings : Animals; Animals, Zoo; Eye / pathology; Female; Gorilla gorilla; Hypertension, Malignant / pathology; Hypertension, Malignant / veterinary; Hypertensive Retinopathy / pathology; Hypertensive Retinopathy / veterinary
TL;DR:
A 34‐year‐old western lowland gorilla presented with peracute blindness and died at the age of 34 after suffering from multiple organ failure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Innate PI3K p110 delta Regulates Th1/Th17 Development and Microbiota-Dependent Colitis
JOURNAL OF IMMUNOLOGY, 192(8), 3958–3968.
MeSH headings : Animals; Antigen-Presenting Cells / immunology; Antigen-Presenting Cells / metabolism; Class Ia Phosphatidylinositol 3-Kinase / genetics; Class Ia Phosphatidylinositol 3-Kinase / metabolism; Colitis / genetics; Colitis / immunology; Colitis / metabolism; Colitis / microbiology; Colitis / pathology; Cytokines / biosynthesis; Disease Models, Animal; Gene Expression Regulation; Immunity, Innate / genetics; Interleukin-10 / biosynthesis; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Intestinal Mucosa / pathology; Macrophages / immunology; Macrophages / metabolism; Male; Mice; Mice, Knockout; Microbiota; TOR Serine-Threonine Kinases / metabolism; Th1 Cells / immunology; Th1 Cells / metabolism; Th17 Cells / immunology; Th17 Cells / metabolism
TL;DR:
The PI3K subunit p110δ controls homeostatic APC–T cell interactions by altering the balance between IL-10 and IL-12/23 and may underlie the pathogenesis of human inflammatory bowel disease and lead to new therapeutic strategies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Histopathological features of equine superficial, nonhealing, corneal ulcers
VETERINARY OPHTHALMOLOGY, 17, 46–52.
author keywords: corneal; equine; indolent; nonhealing; superficial; ulcer
MeSH headings : Animals; Cornea / pathology; Corneal Stroma / pathology; Corneal Ulcer / pathology; Corneal Ulcer / veterinary; Epithelium, Corneal / pathology; Female; Horse Diseases / pathology; Horses; Male; Retrospective Studies
TL;DR:
The most consistent histopathological characteristics of equine chronic, nonhealing, superficial, corneal ulcers include epithelial nonadherence, epithelial dysmaturity and mild to moderate stromal inflammation; however, one set of histopathology characteristics does not definitively define this syndrome in horses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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