Works Published in 2009
Displaying works 121 - 140 of 241 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Perturbation of Defense Pathways by Low-Dose Arsenic Exposure in Zebrafish Embryos
Environmental Health Perspectives, 117(6), 981–987.
Contributors: C. Mattingly* , T. Hampton, K. Brothers, N. Griffin & A. Planchart*
author keywords: arsenic; Comparative Toxicogenomics Database; embryonic development; gene regulatory networks; immunity; microarray; toxicogenomics; transcriptional profiling; zebrafish
MeSH headings : Animals; Arsenic / toxicity; Embryo, Nonmammalian; Gene Expression / drug effects; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Water Pollutants, Chemical / toxicity; Zebrafish / metabolism
TL;DR:
It is demonstrated that arsenic significantly down-regulates expression levels of multiple genes potentially critical for regulating the establishment of an immune response, and provides molecular evidence consistent with phenotypic observations reported in other model systems.
(via Semantic Scholar)
europepmc.org (repository)
Sources: Crossref, NC State University Libraries, ORCID
Added: August 10, 2019
2009 journal article
Chemical databases for environmental health and clinical research
Toxicology Letters, 186(1), 62–65.
author keywords: Chemical; Drug; Database; Toxicogenomics
MeSH headings : Animals; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Environmental Exposure; Environmental Health; Environmental Medicine; Environmental Pollutants / toxicity; Humans; Toxicogenetics
TL;DR:
These databases and their associated resources are incrementally strengthening the expanding field of toxicogenomics-based research by providing centralized sources of manually and computationally curated datasets and highly sophisticated tools for the meta-analysis of continually increasing environmental chemical, drug and small-molecule datasets.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2009 journal article
Genetic and environmental pathways to complex diseases
BMC Systems Biology, 3(1), 46.
MeSH headings : Databases, Genetic; Disease / genetics; Environment; Evolution, Molecular; Gene Expression Regulation; Genome-Wide Association Study; Genotype; Humans; Mental Disorders / etiology; Mental Disorders / genetics; Mental Disorders / metabolism; Mental Disorders / pathology; Metabolic Diseases / etiology; Metabolic Diseases / genetics; Metabolic Diseases / metabolism; Metabolic Diseases / pathology; Phenotype; Transcription, Genetic
TL;DR:
This analysis identifies natural and synthetic retinoids, antipsychotic medications, Omega 3 fatty acids, and pyrethroid pesticides as potential environmental modulators of metabolic syndrome phenotypes through PPAR and adipocytokine signaling and organophosphate pesticides as potential environmental modulators of neuropsychiatric phenotypes.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2009 journal article
Comparative Toxicogenomics Database: a knowledgebase and discovery tool for chemical-gene-disease networks
Nucleic Acids Research, 37(Database), D786–D792.
MeSH headings : Databases, Factual; Disease / etiology; Disease / genetics; Environmental Exposure; Genes; Genomics; Hazardous Substances / toxicity; Humans; Models, Biological; Proteins / drug effects; Proteins / genetics; Systems Integration; Toxicogenetics
TL;DR:
The Comparative Toxicogenomics Database is a curated database that promotes understanding about the effects of environmental chemicals on human health by integrating data to be integrated to construct chemical–gene–disease networks.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2009 journal article
GeneComps and ChemComps: a new CTD metric to identify genes and chemicals with shared toxicogenomic profiles
Bioinformation, 4(4), 173–174.
author keywords: gene; chemical; toxicogenomic; database; curation
TL;DR:
GeneComps and ChemComps are now provided for every curated gene and chemical in CTD and provide a novel way to view and classify genes and chemicals and will help advance testable hypotheses about environmental chemical-genedisease networks.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2009 journal article
Sp2 Is a Maternally Inherited Transcription Factor Required for Embryonic Development
Journal of Biological Chemistry, 285(6), 4153–4164.
MeSH headings : Amino Acid Sequence; Animals; COS Cells; Chlorocebus aethiops; Chromosome Mapping; Embryo, Mammalian / embryology; Embryo, Mammalian / metabolism; Female; Gene Expression Regulation, Developmental; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Humans; In Situ Hybridization; Male; Mice; Microscopy, Fluorescence; Molecular Sequence Data; Phylogeny; Promoter Regions, Genetic / genetics; RNA, Messenger, Stored / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sp2 Transcription Factor / classification; Sp2 Transcription Factor / genetics; Sp2 Transcription Factor / metabolism; Synteny; Transcription, Genetic; Zebrafish / embryology; Zebrafish / genetics; Zebrafish / growth & development; Zebrafish Proteins / genetics; Zebrafish Proteins / metabolism
TL;DR:
The role(s) played by Sp2 in early metazoan development is addressed by cloned and characterized Sp2 from zebrafish, and the intron/exon organization and amino acid sequence of Sp2 is closely conserved with its mammalian orthologues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 21, 2019
2009 journal article
Developmental and tissue-specific expression of NITRs
Immunogenetics, 62(2), 117–122.
author keywords: Innate immunity; Lymphocytes; Natural killer receptors
MeSH headings : Animals; Embryo, Nonmammalian / metabolism; Female; Gene Expression Regulation, Developmental; Organ Specificity; Ovary / metabolism; Receptors, Immunologic / genetics; Receptors, Immunologic / immunology; Zebrafish / embryology; Zebrafish / genetics; Zebrafish / immunology; Zebrafish / metabolism; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
The expression of multiple NITR genes in the zebrafish ovary and during embryogenesis is demonstrated and all 14 families of NITRs are shown to be expressed in the lymphocyte lineage, but not in the myeloid lineage, consistent with the hypothesis that N ITRs function as NKRs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: NC State University Libraries, Crossref
Added: May 17, 2019
2009 journal article
Thermosensitive Nanocables Prepared by Surface-Initiated Atom Transfer Radical Polymerization
Nanoscale Research Letters, 4(1), 84–89.
author keywords: Nanocables; Gold nanowires; Poly(N-isopropylacrylamide); Surface-initiated atom transfer radical polymerization Thermoresponsive
TL;DR:
Smart nanocables consisting of Au nanowire cores and poly(N-isopropylacrylamide) sheaths (denoted as Au/PNIPAAm) show immense potentials as building blocks for novel thermosensitive nanodevices in future.
(via Semantic Scholar)
Source: ORCID
Added: March 21, 2019
2009 journal article
Gyromagnetic Imaging: Dynamic Optical Contrast Using Gold Nanostars with Magnetic Cores
Journal of the American Chemical Society, 131(28), 9728–9734.
MeSH headings : Biological Transport; Gold / chemistry; Gold / metabolism; Humans; KB Cells; Luminescence; Magnetics; Metal Nanoparticles / chemistry; Motion; Optical Phenomena; Rotation; Time Factors; Tomography, Optical Coherence
TL;DR:
Gyromagnetic imaging of nanostars inside of tumor cells is demonstrated, using broadband excitation: while their time- domain signals are obscured by incoherent scattering, their Fourier-domain signals can be clearly resolved in less than a second.
(via Semantic Scholar)
Source: ORCID
Added: March 21, 2019
2009 journal article
Gold Nanorods as Contrast Agents for Biological Imaging: Optical Properties, Surface Conjugation and Photothermal Effects
Photochemistry and Photobiology, 85(1), 21–32.
Contributors: L. Tong *, Q. Wei* , A. Wei * & J. Cheng *
MeSH headings : Animals; Contrast Media / chemistry; Gold / chemistry; Humans; Molecular Probe Techniques; Nanotubes / chemistry; Photochemical Processes; Surface Properties
TL;DR:
The combination of plasmon‐resonant optical properties, intense local photothermal effects and robust surface chemistry render gold NRs as promising theragnostic agents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: March 21, 2019
2009 journal article
COLL 347-Polarization-sensitive NIR imaging modalities based on gold nanorods and nanostars
Abstracts of Papers of the American Chemical Society, 238. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000207861903202&KeyUID=WOS:000207861903202
Contributors: Q. Wei , H. Song, A. Leonov, K. Ritchie & A. Wei
Source: ORCID
Added: March 21, 2019
2009 journal article
The fungal-mineral interface: Challenges and considerations of micro-analytical developments
Fungal Biology Reviews, 23(4), 122–131.
Contributors: M. Smits*, A. Herrmann *, M. Duane*, O. Duckworth n , S. Bonneville*, L. Benning *, U. Lundström*
TL;DR:
Modern microscopy, spectroscopy, mass spectrometry, wet chemistry, and scattering techniques allow for the selective extraction of physical, chemical, and structural data at the micro- to nano-scale and offer exciting possibilities to study fungal–mineral interactions at the scale of individual hyphae.
(via Semantic Scholar)
Source: ORCID
Added: February 5, 2019
2009 journal article
A Volunteer-Led Effort Linking Research to Development Practice to Promote Safe Water and Hygiene in Slums in India
Proceedings of the Water Environment Federation, 1, 523–539.
Sources: NC State University Libraries, NC State University Libraries
Added: January 30, 2019
2009 journal article
Increased lung cancer risks are similar whether arsenic is ingested or inhaled
Journal of Exposure Science & Environmental Epidemiology, 19(4), 343–348.
MeSH headings : Administration, Oral; Arsenic / administration & dosage; Arsenic / toxicity; Carcinogens / administration & dosage; Carcinogens / toxicity; Case-Control Studies; Cohort Studies; Dose-Response Relationship, Drug; Humans; Inhalation Exposure; Lung Neoplasms / chemically induced; Risk Assessment
TL;DR:
It is concluded that lung cancer risks probably depend on absorbed dose, and not on whether inorganic arsenic is ingested or inhaled, which is similar for the two routes of exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: January 30, 2019
2009 journal article
The soul of a polarized democracy: Testing theoretical linkages between talk and attitude extremity during the 2004 presidential election
Communication Research, 36(3), 315–340.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Provisional Advisory Levels (PALs) for hydrogen sulfide (H2S)
INHALATION TOXICOLOGY, 21, 56–72.
author keywords: PALs; hydrogen sulfide; emergency planning; inhalation; drinking water
MeSH headings : Animals; Consultants; Environmental Exposure / adverse effects; Environmental Exposure / standards; Humans; Hydrogen Sulfide / adverse effects; Hydrogen Sulfide / chemistry; Hydrogen Sulfide / standards; Inhalation Exposure / standards; Occupational Exposure / adverse effects; Occupational Exposure / standards
TL;DR:
Application of Provisional Advisory Levels (PALs) protocols was performed for hydrogen sulfide (H2S) as experimental data permitted, and no reliable data were found on oral exposure, making it impractical to estimate PALs for drinking water.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 review
Provisional Advisory Levels (PALs) for acrylonitrile
[Review of ]. INHALATION TOXICOLOGY, 21, 17–55.
author keywords: PALs; acrylonitrile; emergency response; inhalation; drinking water
MeSH headings : Acrylonitrile / adverse effects; Acrylonitrile / chemistry; Acrylonitrile / standards; Animals; Consultants; Environmental Exposure / adverse effects; Environmental Exposure / standards; Humans; Inhalation Exposure / adverse effects; Inhalation Exposure / standards; Occupational Exposure / adverse effects; Occupational Exposure / standards
TL;DR:
This study characterize the key physical processes related to formation and growth of nanoparticles and two of the main protection techniques are ventilation and filtration, which are widely used in practical applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Morphogenesis of the Primitive Gut Tube Is Generated by Rho/ROCK/Myosin II-Mediated Endoderm Rearrangements
DEVELOPMENTAL DYNAMICS, 238(12), 3111–3125.
author keywords: gut; Xenopus; morphogenesis; endoderm, intercalation; elongation
MeSH headings : Animals; Animals, Genetically Modified; Body Patterning / genetics; Cell Polarity / genetics; Cell Shape / genetics; Embryo, Nonmammalian; Endoderm / cytology; Endoderm / embryology; Endoderm / metabolism; Gastrointestinal Diseases / congenital; Gastrointestinal Diseases / embryology; Gastrointestinal Tract / abnormalities; Gastrointestinal Tract / embryology; Gastrula / embryology; Gastrula / metabolism; Models, Biological; Morphogenesis / genetics; Nonmuscle Myosin Type IIB / genetics; Nonmuscle Myosin Type IIB / metabolism; Nonmuscle Myosin Type IIB / physiology; Signal Transduction / genetics; Xenopus / embryology; Xenopus / genetics; Xenopus / metabolism; rho-Associated Kinases / genetics; rho-Associated Kinases / metabolism; rho-Associated Kinases / physiology; rhoA GTP-Binding Protein / genetics; rhoA GTP-Binding Protein / metabolism; rhoA GTP-Binding Protein / physiology
TL;DR:
The results suggest that the cellular and molecular events driving tissue elongation in the PGT are mechanistically analogous to those that function during gastrulation, but occur within a novel cylindrical geometry to generate an epithelial‐lined tube.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
An Animated Model of Reticulorumen Motility
JOURNAL OF VETERINARY MEDICAL EDUCATION, 36(4), 444–450.
author keywords: animated model; eructation; reticulorumen motility; rumination; student preference
MeSH headings : Animals; Attitude of Health Personnel; Computer Simulation; Computer-Assisted Instruction / methods; Education, Veterinary / methods; Educational Measurement; Gastrointestinal Motility / physiology; Humans; Models, Biological; Reticulum / physiology; Rumen / physiology; Ruminants / anatomy & histology; Ruminants / physiology; Students / psychology
TL;DR:
An animated model of reticulorumen motility was developed and hypothesized that veterinary students would prefer use of the model over traditional instructional methods and would recommend the model to other veterinary students.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
RNA interference-mediated knock-down ofBla g 1in the German cockroach,Blattella germanicaL., implicates this allergen-encoding gene in digestion and nutrient absorption
Insect Molecular Biology, 18(6), 727–736.
Contributors: A. Suazo n, C. Gore & C. Schal n
author keywords: Blattella germanica; RNA interference; midgut protein; Bla g 1; allergen
MeSH headings : Allergens / genetics; Allergens / metabolism; Allergens / physiology; Animals; Antigens, Plant; Cockroaches / genetics; Cockroaches / growth & development; DNA Primers / genetics; Digestion / genetics; Digestion / physiology; Female; Intestinal Absorption / genetics; Juvenile Hormones / pharmacology; Oocytes / metabolism; RNA Interference; Reproduction / drug effects; Reproduction / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
Exogenous juvenile hormone treatments rescued reproduction in RNAi‐treated females, suggesting that Bla g 1 silencing lowered endogenous juvenile hormone, probably by reducing food intake and nutrient absorption.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
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