Works Published in 2010
Displaying works 21 - 40 of 99 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Mortality in the Agricultural Health Study, 1993-2007
American Journal of Epidemiology, 173(1), 71–83.
author keywords: agriculture; healthy worker effect; mortality; neoplasms; pesticides; wounds and injuries
MeSH headings : Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / mortality; Cause of Death / trends; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Pesticides / adverse effects; Retrospective Studies; Survival Rate / trends
TL;DR:
Using data from the Agricultural Health Study, a cohort of 89,656 pesticide applicators and their spouses in North Carolina and Iowa, standardized mortality ratios (SMRs) were computed comparing deaths from time of the enrollment through 2007 to state-specific rates.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020
2010 journal article
Gestational exposure to bisphenol A and cross-fostering affect behaviors in juvenile mice
Hormones and Behavior, 58(5), 754–761.
author keywords: Endocrine disruptive compounds; Estrogens; Epigenetic; Environment; Methylation; Sex differences; Bisphenol A
MeSH headings : Air Pollutants / toxicity; Animal Husbandry; Animals; Animals, Newborn; Anxiety / chemically induced; Behavior, Animal / drug effects; Behavior, Animal / physiology; Benzhydryl Compounds; Exploratory Behavior / drug effects; Exploratory Behavior / physiology; Female; Male; Maternal Deprivation; Maternal Exposure / adverse effects; Maze Learning / drug effects; Maze Learning / physiology; Mice; Mice, Inbred C57BL; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / physiopathology; Prenatal Exposure Delayed Effects / psychology
TL;DR:
The results show that prenatal BPA exposure affects social behavior and anxiety in the EPM, and some facet(s) of the infant-maternal interaction may modify these effects.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Of mice and rats: Key species variations in the sexual differentiation of brain and behavior
Frontiers in Neuroendocrinology, 31(3), 341–358.
author keywords: Hypothalamus; Calbindin D28k; Progestin receptor; Estrogen receptor; Nitric oxide; Sexual dimorphism
MeSH headings : Animals; Behavior, Animal / physiology; Brain / growth & development; Brain / physiology; Humans; Mice; Models, Animal; Rats; Sex Differentiation / physiology; Sexual Behavior, Animal / physiology; Species Specificity
TL;DR:
Neural and behavioral sexual dimorphisms in rats and mice are reviewed, which highlight species differences and experimental gaps in the literature, that are needed for direct species comparisons.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Critical periods of susceptibility to short-term energy challenge during pregnancy: Impact on fertility and offspring development
Physiology & Behavior, 99(1), 100–108.
author keywords: Reproduction; Pregnancy; Fertility; Gestation; Delayed implantation; Energy balance; Food restriction; Sexual behavior; Development
MeSH headings : Analysis of Variance; Animals; Body Weight; Disease Susceptibility; Eating / physiology; Fasting / physiology; Female; Fertility / physiology; Fetal Development / physiology; Litter Size; Male; Nutritional Status; Pregnancy / physiology; Pregnancy Outcome; Pregnancy, Animal; Sexual Behavior, Animal; Shrews; Time Factors
TL;DR:
There are critical periods of pregnancy, particularly after implantation, when short-term, mild energetic challenges have significant impacts on fertility and offspring postnatal development, and delayed implantation may have evolved, in part, as a buffering mechanism to prevent pregnancy failure during impaired energy balance in early gestation.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Maternally-inherited Grb10 reduces placental size and efficiency
Developmental Biology, 337(1), 1–8.
author keywords: Adapter protein; Cell signalling; Epigenetics; Genomic imprinting; Growth factor receptor-bound protein; Growth regulation; IGF; Insulin-like growth factor; Mouse; Placenta
MeSH headings : Alleles; Animals; Endothelium / metabolism; Female; GRB10 Adaptor Protein / analysis; GRB10 Adaptor Protein / genetics; GRB10 Adaptor Protein / physiology; Genomic Imprinting; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Placenta / pathology; Placenta / physiology; Pregnancy
TL;DR:
It is shown that following disruption of the maternal allele in mice, the labyrinthine volume was increased in a manner consistent with a cell-autonomous function of Grb10 and the enlarged placenta was more efficient in supporting foetal growth, becoming the first example of a gene that acts to limit placental size and efficiency.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2010 journal article
Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus
Proceedings of the National Academy of Sciences, 107(10), 4693–4698.
author keywords: epithelial growth factor receptor; host pathogen; microarray; Streptococcus pyogenes; transcriptome
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Clathrin-Coated Vesicles / metabolism; Cytokines / metabolism; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Gene Expression Profiling; Host-Pathogen Interactions; Hyaluronic Acid / metabolism; Macaca fascicularis / genetics; Macaca fascicularis / metabolism; Macaca fascicularis / microbiology; Neutrophils / metabolism; Neutrophils / microbiology; Neutrophils / pathology; Oligonucleotide Array Sequence Analysis; Pharyngitis / genetics; Pharyngitis / microbiology; Pharynx / metabolism; Pharynx / microbiology; Pharynx / pathology; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pyogenes / genetics; Streptococcus pyogenes / metabolism; Streptococcus pyogenes / physiology
TL;DR:
These results are unique in providing a comprehensive understanding of the host–pathogen interactome during mucosal infection by a bacterial pathogen.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans
Clinical Pharmacology & Therapeutics, 88(1), 45–51.
MeSH headings : Acetaminophen / adverse effects; Acetaminophen / metabolism; Acetaminophen / pharmacology; Adolescent; Adult; Alanine Transaminase / blood; Analgesics, Non-Narcotic / adverse effects; Analgesics, Non-Narcotic / metabolism; Analgesics, Non-Narcotic / pharmacology; Biotransformation; Chemical and Drug Induced Liver Injury / diagnosis; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / urine; Cohort Studies; Data Interpretation, Statistical; Female; Humans; Least-Squares Analysis; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Young Adult
TL;DR:
It is demonstrated that the pattern of endogenous metabolites in urine could predict susceptibility to acetaminophen‐induced liver injury in rats, and this “early‐intervention pharmaco‐metabonomics” approach should now be tested in clinical trials of other potentially hepatotoxic drugs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2010 journal article
An approximate Bayesian approach for quantitative trait loci estimation
Computational Statistics & Data Analysis, 54(2), 565–574.
TL;DR:
This paper presents a Bayesian linkage model that offers directly interpretable posterior densities or Bayes factors for linkage, and employs the Laplace approximation for integration over nuisance parameters in backcross (BC) and F2 intercross designs.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2010 journal article
Heterotaxin: A novel TGF-beta signaling inhibitor identified in a multi-phenotype profiling screen in Xenopus embryos
Developmental Biology, 344(1), 526.
TL;DR:
A small molecule screen for left-right asymmetry phenotypes in Xenopus embryos is performed and a novel pyridine analog, heterotaxin, is discovered, which disrupts both cardiovascular and digestive organ laterality and inhibits TGF-β-dependent left- right asymmetric gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2010 journal article
Rhinitis Associated with Pesticide Use Among Private Pesticide Applicators in the Agricultural Health Study
Journal of Toxicology and Environmental Health, Part A, 73(20), 1382–1393.
Contributors: R. Slager*, S. Simpson *, T. Levan*, J. Poole *, D. Sandler * & J. Hoppin*
MeSH headings : Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Animals; Captan; Cohort Studies; Diazinon; Female; Humans; Iowa / epidemiology; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure / adverse effects; Odds Ratio; Pesticides / adverse effects; Pesticides / classification; Petroleum; Rhinitis / chemically induced; Rhinitis / epidemiology; Risk Factors; Surveys and Questionnaires; Time Factors; Young Adult
TL;DR:
Specific pesticides may contribute to rhinitis in farmers; agricultural activities did not explain these findings.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Thyroid Disease Among Women in the Agricultural Health Study
American Journal of Epidemiology, 171(4), 455–464.
Contributors: W. Goldner, D. Sandler, F. Yu, J. Hoppin* , F. Kamel & T. Levan
author keywords: agriculture; environmental exposure; hyperthyroidism; hypothyroidism; pesticides; thyroid gland
MeSH headings : Agriculture; Cross-Sectional Studies; Environmental Exposure; Female; Fumigation / adverse effects; Fungicides, Industrial / toxicity; Herbicides / toxicity; Humans; Iowa / epidemiology; Logistic Models; North Carolina / epidemiology; Pesticides / toxicity; Prevalence; Prospective Studies; Spouses; Thyroid Diseases / chemically induced; Thyroid Diseases / epidemiology
TL;DR:
Data support a role of organochlorines, in addition to fungicides, in the etiology of thyroid disease among female spouses enrolled in the Agricultural Health Study.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Within-person variability in urinary phthalate metabolite concentrations: Measurements from specimens after long-term frozen storage
Journal of Exposure Science and Environmental Epidemiology, 20(2), 169–175.
Contributors: D. Baird*, T. Saldana*, P. Nepomnaschy*, J. Hoppin* , M. Longnecker*, C. Weinberg *, A. Wilcox *
author keywords: biomarker; phthalate; reproducibility; menstrual cycle; temporal variability
MeSH headings : Cryopreservation; Female; Freezing; Humans; Menstrual Cycle; Phthalic Acids / urine; Reference Standards; Reproducibility of Results
TL;DR:
Results suggest that the measurement of phthalate metabolites after long-term sample storage yield generally similar distributions and temporal reliability as those reported for recently collected specimens, and support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence ofphthalate exposures on later outcomes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2010 journal article
Urinary biomarker, dermal, and air measurement results for 2,4-D and chlorpyrifos farm applicators in the Agricultural Health Study
Journal of Exposure Science and Environmental Epidemiology, 20(2), 119–134.
Contributors: K. Thomas *, M. Dosemeci*, J. Hoppin* , L. Sheldon*, C. Croghan*, S. Gordon*, M. Jones *, S. Reynolds*
author keywords: 2,4-D; chlorpyrifos; exposure measurement; farm applicator; occupational exposure; Agricultural Health Study
MeSH headings : 2,4-Dichlorophenoxyacetic Acid / analysis; 2,4-Dichlorophenoxyacetic Acid / urine; Biomarkers / urine; Chlorpyrifos / analysis; Chlorpyrifos / urine; Humans; Skin / chemistry
Source: ORCID
Added: September 13, 2019
2010 journal article
Occupational exposure to terbufos and the incidence of cancer in the Agricultural Health Study
Cancer Causes & Control, 21(6), 871–877.
Contributors: M. Bonner *, B. Williams *, J. Rusiecki *, A. Blair*, L. Beane Freeman*, J. Hoppin* , M. Dosemeci*, J. Lubin*, D. Sandler *, M. Alavanja*
author keywords: Cancer incidence; Terbufos; Organophosphate insecticides
MeSH headings : Agriculture; Carcinogens; Data Collection; Humans; Incidence; Insecticides; Iowa / epidemiology; Leukemia / complications; Leukemia / epidemiology; Lymphoma, Non-Hodgkin / complications; Lymphoma, Non-Hodgkin / epidemiology; Male; Neoplasms / complications; Neoplasms / epidemiology; Nervous System Neoplasms / complications; Nervous System Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Organophosphorus Compounds; Organothiophosphorus Compounds; Patients; Pesticides; Surveys and Questionnaires
TL;DR:
C cautious interpretation of these results is warranted by the lack of existing experimental and epidemiologic evidence to support carcinogenic effects of terbufos, but suggestive associations between occupational ter bufos use and several cancer sites are found.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use and Myocardial Infarction Incidence Among Farm Women in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 52(7), 693–697.
Contributors: S. Dayton*, D. Sandler *, A. Blair*, M. Alavanja*, L. Beane Freeman* & J. Hoppin*
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Female; Humans; Incidence; Iowa / epidemiology; Middle Aged; Myocardial Infarction / chemically induced; Myocardial Infarction / epidemiology; North Carolina / epidemiology; Occupational Exposure; Pesticides / adverse effects; Prospective Studies; Risk Factors; Women's Health; Young Adult
TL;DR:
Pesticides may contribute to MI risk among farm women and six of 27 individual pesticides evaluated were significantly associated with nonfatal MI, including chlorpyrifos, coumaphos, carbofuran, metalaxyl, pendimethalin, and trifluralin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Pesticide Use Modifies the Association Between Genetic Variants on Chromosome 8q24 and Prostate Cancer
Cancer Research, 70(22), 9224–9233.
Contributors: S. Koutros *, L. Beane Freeman*, S. Berndt *, G. Andreotti *, J. Lubin*, D. Sandler *, J. Hoppin* , K. Yu *
MeSH headings : Adult; Aged; Chromosomes, Human, Pair 8 / genetics; Coumaphos / poisoning; Fonofos / poisoning; Genome-Wide Association Study; Humans; Incidence; Iowa / epidemiology; Logistic Models; Male; Middle Aged; North Carolina / epidemiology; Occupational Diseases / chemically induced; Occupational Diseases / epidemiology; Occupational Diseases / genetics; Odds Ratio; Organothiophosphorus Compounds / poisoning; Permethrin / poisoning; Pesticides / poisoning; Phorate / poisoning; Polymorphism, Single Nucleotide; Prospective Studies; Prostatic Neoplasms / chemically induced; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / genetics; Risk Assessment; Risk Factors
TL;DR:
A significant interaction among variants on chromosome 8q24, pesticide use, and risk of prostate cancer was observed, and Insecticides, particularly organophosphates, were the strongest modifiers of risk, although the biological mechanism is unclear.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Coumaphos Exposure and Incident Cancer among Male Participants in the Agricultural Health Study (AHS)
Environmental Health Perspectives, 118(1), 92–96.
Contributors: C. Christensen*, E. Platz *, G. Andreotti *, A. Blair*, J. Hoppin* , S. Koutros *, C. Lynch *, D. Sandler *, M. Alavanja*
author keywords: agriculture; cancer; coumaphos; insecticide; livestock; neoplasms; occupational exposure; organophosphate; pesticide; prostate
MeSH headings : Adult; Aged; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / etiology; Animal Husbandry; Cohort Studies; Coumaphos / administration & dosage; Coumaphos / toxicity; Genetic Predisposition to Disease; Humans; Insecticides / administration & dosage; Insecticides / toxicity; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure; Occupational Health; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Prostatic Neoplasms / genetics; Risk Assessment; Surveys and Questionnaires; Young Adult
TL;DR:
Cumulative exposure to coumaphos was not associated with cancer risk overall or with any major cancer site including prostate, and there was evidence of an association between cou maphos and prostate cancer, possibly due to genetic susceptibility; however, other explanations are plausible.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Maternal Pesticide Use and Birth Weight in the Agricultural Health Study
Journal of Agromedicine, 15(2), 127–136.
Contributors: S. Sathyanarayana*, O. Basso *, C. Karr *, P. Lozano *, M. Alavanja*, D. Sandler *, J. Hoppin*
author keywords: Agricultural exposures; birth weight; carbaryl; pesticides; reproductive epidemiology
MeSH headings : Adolescent; Adult; Agriculture; Carbaryl / adverse effects; Female; Health Surveys; Humans; Infant, Low Birth Weight; Infant, Newborn; Insecticides / adverse effects; Iowa; Male; Maternal Exposure / adverse effects; Middle Aged; Mothers; North Carolina; Occupational Exposure / adverse effects; Occupational Health; Pregnancy; Pregnancy Trimester, First / metabolism; Young Adult
TL;DR:
Overall, the authors observed no associations between birth weight and pesticide-related activities during early pregnancy and have no data on temporal specificity of individual pesticide exposures prior to or during pregnancy and therefore cannot draw conclusions related to these exposure windows.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2010 journal article
Effects of self-reported health conditions and pesticide exposures on probability Of Follow-Up in a prospective cohort study
American Journal of Industrial Medicine, 53(5), 486–496.
Contributors: M. Montgomery *, F. Kamel*, J. Hoppin* , L. Freeman*, M. Alavanja* & D. Sandler *
author keywords: selection bias; follow-up studies; prospective studies; cohort studies; pesticides; agriculture
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agriculture; Confidence Intervals; Female; Humans; Iowa / epidemiology; Logistic Models; Male; Middle Aged; Multivariate Analysis; North Carolina / epidemiology; Occupational Diseases / epidemiology; Occupational Diseases / etiology; Occupational Exposure / adverse effects; Odds Ratio; Patient Acceptance of Health Care; Pesticides / toxicity; Probability; Prospective Studies; Risk Assessment; Risk Factors; Selection Bias; Surveys and Questionnaires; Time Factors; United States / epidemiology; Young Adult
TL;DR:
Differences between non-participants and participants in the follow-up interview were generally small, and significant evidence of selection bias was found, however, the extent of bias may depend on the specific exposure and outcome under study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
Source: ORCID
Added: September 13, 2019
2010 journal article
Identification of Iowa Live Births in the Agricultural Health Study
Archives of Environmental & Occupational Health, 65(3), 154–162.
Contributors: P. Romitti *, S. Watanabe-Galloway *, W. Budelier*, C. Lynch *, S. Puzhankara*, D. Wong-Gibbons*, J. Hoppin* , M. Alavanja*
author keywords: children; occupational exposures; pesticides; pregnancy; prospective cohort
MeSH headings : Agricultural Workers' Diseases / epidemiology; Agriculture / statistics & numerical data; Birth Certificates; Family Characteristics; Female; Health Surveys; Humans; Iowa / epidemiology; Live Birth / epidemiology; Male; Occupational Exposure / adverse effects; Occupational Exposure / statistics & numerical data; Parity; Pregnancy
TL;DR:
A probabilistic and deterministic approach was used to link available demographic data from 31,707 households and information on live births from 13,599 households with 1,014,916 Iowa birth certificates, producing an expanded cohort of live-born children among Iowa participants.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
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