Works Published in 2018

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Displaying works 161 - 180 of 252 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Intestinal Metabolism and Bioaccumulation of Sucralose In Adipose Tissue In The Rat

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 81(18), 913–923.

By: V. Bornemann*, S. Werness, L. Buslinger n & S. Schiffman n

MeSH headings : Adipose Tissue / metabolism; Animals; Chromatography, High Pressure Liquid; Feces / chemistry; Female; Intestinal Mucosa / metabolism; Male; Rats; Rats, Sprague-Dawley; Sucrose / analogs & derivatives; Sucrose / metabolism; Sucrose / urine; Sweetening Agents / metabolism; Tandem Mass Spectrometry; Time Factors
TL;DR: New findings of metabolism of sucralose in the gastrointestinal tract (GIT) and its accumulation in adipose tissue were not part of the original regulatory decision process for this agent and indicate that it now may be time to revisit the safety and regulatory status of this organochlorine artificial sweetener. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: November 26, 2018

2018 journal article

Long-lived triplet excited state in a platinum(ii) perylene monoimide complex

DALTON TRANSACTIONS, 47(42), 15071–15081.

TL;DR: The synthesis and solution based photophysical properties of a new Pt(ii)-terpyridine complex coupled to a perylene monoimide (PMI) chromophoric unit through an acetylene linkage resulted in quantitative quenching of the highly fluorescent PMI chromophore by introducing metal character into the lowest energy singlet state, thereby leading to the formation of a long-lived PMI-ligand localized triplet excited state. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 26, 2018

2018 journal article

Carbon-Fiber Microbiosensor for Monitoring Rapid Lactate Fluctuations in Brain Tissue Using Fast-Scan Cyclic Voltammetry

Analytical Chemistry, 90(21), 12994–12999.

By: S. Smith n, S. Gosrani n, C. Lee n, G. McCarty n & L. Sombers n

MeSH headings : Animals; Biosensing Techniques / methods; Carbon Fiber / chemistry; Electrochemical Techniques / instrumentation; Electrochemical Techniques / methods; Enzymes, Immobilized / chemistry; Lactic Acid / analysis; Limit of Detection; Male; Microelectrodes; Mixed Function Oxygenases / chemistry; Neostriatum / metabolism; Rats, Sprague-Dawley; Sensitivity and Specificity
TL;DR: There is evidence that striatal lactate availability increases biphasically in response to electrical stimulation of the dopaminergic midbrain in the anesthetized rat, and this new tool for real-time detection of lactate dynamics promises to improve understanding of how lactateavailability underscores neuronal function and dysfunction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

Bathophenanthroline Disulfonate Ligand-Induced Self-Assembly of Ir(III) Complexes in Water: An Intriguing Class of Photoluminescent Soft Materials

ACS Omega, 3(10), 14027–14038.

By: M. McGoorty n, A. Singh n, T. Deaton n, B. Peterson n, C. Taliaferro n, Y. Yingling n, F. Castellano n

TL;DR: A combination of nanoscale particle characterization techniques, static and dynamic photoluminescence spectroscopic studies, along with atomistic molecular dynamics simulations of these soft materials suggests the formation of small, heterogeneous nanoaggregate structures, wherein the sulfonated diimine ancillary ligand serves as a pro-aggregating subunit in all instances. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

Quasi-Resonance Signal Amplification by Reversible Exchange

The Journal of Physical Chemistry Letters, 9(20), 6136–6142.

TL;DR: The 15N hyperpolarization levels attained with QUASR-SABRE on metronidazole-15N2-13C2 were more than 2-fold greater than those with SABRE-SHEATH (SABRE in shield enables alignment transfer to heteronuclei), demonstrating that QUASr-SA BRE can deliver significantly more efficient means of SABre hyperpolarsization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 19, 2018

2018 journal article

Machine Learning Reveals Protein Signatures in CSF and Plasma Fluids of Clinical Value for ALS

SCIENTIFIC REPORTS, 8.

By: M. Bereman n, J. Beri n, J. Enders n & T. Nash n

MeSH headings : Amyotrophic Lateral Sclerosis / blood; Amyotrophic Lateral Sclerosis / cerebrospinal fluid; Amyotrophic Lateral Sclerosis / metabolism; Humans; Machine Learning; Multivariate Analysis; Proteomics
TL;DR: The potential of a panel of targeted proteins for objective measurements of clinical value in ALS is demonstrated, and three proteins composed a prognostic model that explained 49% of the variation in the ALS-FRS scores. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: November 19, 2018

2018 journal article

2-Aminobenzimidazoles as antibiofilm agents against Salmonella enterica serovar Typhimurium

MEDCHEMCOMM, 9(9), 1547–1552.

By: W. Huggins n, T. Nguyen n, N. Hahn n, J. Baker n, L. Kuo*, D. Kaur*, R. Melander n, J. Gunn*, C. Melander

TL;DR: Modifications to the head, tail, and linker regions of the original hit compound elucidated new, more effective analogues that inhibit S. enterica serovar Typhimurium biofilm formation while being non-toxic to planktonic bacterial growth. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: November 12, 2018

2018 journal article

Synergy of Silane and Polyacrylate Treatments to Prepare Thermally Stable and Hydrophobic Cellulose Nanocrystals

CHEMISTRY LETTERS, 47(10), 1272–1275.

author keywords: Cellulose nanocrystals; Hydrophobicity; Thermal stability
Source: Web Of Science
Added: November 5, 2018

2018 journal article

Mechanistic Elucidation of Two Catalytically Versatile Iron(II)- and -Ketoglutarate-Dependent Enzymes: Cases Beyond Hydroxylation

COMMENTS ON INORGANIC CHEMISTRY, 38(4), 127–165.

Contributors: W. Chang n, P. Liu* & Y. Guo*

author keywords: alpha-ketoglutarate-dependentenzyme; Ferryl intermediate; Endoperoxidation; Epoxidation; Desaturation
TL;DR: The mechanisms of two newly discovered Fe/αKG enzymes are studied, revealing their strategies in controlling reactivity, namely the effect of redox/polar residues near the iron center, the electronic properties of the substrate, and the intrinsic reactivity of the ferryl intermediate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 29, 2018

2018 journal article

Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions

DRUG SAFETY, 41(11), 1059–1072.

By: M. La*, A. Sedykh, D. Fourches n, E. Muratov & A. Tropsha

MeSH headings : Data Mining / methods; Databases, Factual; Drug-Related Side Effects and Adverse Reactions / epidemiology; Humans; Prescription Drugs / adverse effects; Prescription Drugs / pharmacology; Proteins / drug effects
TL;DR: The presented workflow, based on free-access databases and an association-based inference scheme, provided novel C–E relationships that have been validated post hoc in case reports and may provide an effective computational method for the early detection of potential drug candidate ADEs that can be followed by targeted experimental investigations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 29, 2018

2018 journal article

Spin-Density Wave as a Superposition of Two Magnetic States of Opposite Chirality and Its Implications

INORGANIC CHEMISTRY, 57(16), 9782–9785.

By: E. Gordon n, S. Derakhshan*, C. Thompson* & M. Whangho

TL;DR: A magnetic solid with weak spin frustration tends to adopt a noncollinear magnetic structure such as a cycloidal structure below a certain temperature and a spin-density wave (SDW) slightly above this temperature, and whether a SDW is transversal or longitudinal is governed by the magnetic anisotropy of magnetic ions. (via Semantic Scholar)
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Cause for the Orbital Ordering of Cs2AgF4 and Its Effect on Thermoelectric Properties

INORGANIC CHEMISTRY, 57(19), 11895–11900.

TL;DR: The orbital-ordering opens a bandgap at the Fermi level and generates peaks in the density of states at the conduction band minimum (CBM) and valence band maximum (VBM), Consequently, orthorhombic Cs2AgF4 has strongly enhanced Seebeck coefficients as compared to tetragonal Cs 2 AgF4. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Diffusion of Nanocars on an Air-Glass Interface

JOURNAL OF PHYSICAL CHEMISTRY C, 122(33), 19025–19036.

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Energy Transfer Dynamics in Triplet–Triplet Annihilation Upconversion Using a Bichromophoric Heavy-Atom-Free Sensitizer

The Journal of Physical Chemistry A, 122(33), 6673–6682.

TL;DR: The ultralong excited state lifetime characteristic of the DBP triplet was shown to be crucial for enhancing the intermolecular TTET efficiency and the subsequent triplet-triplet annihilation photochemistry. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: October 19, 2018

2018 journal article

3-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones as novel antibacterial scaffolds against methicillin-resistant Staphylococcus aureus

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 28(16), 2732–2735.

author keywords: Natural products; Antibiotics; Heterocycles; Cyclization; Medicinal chemistry
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Dose-Response Relationship, Drug; Methicillin Resistance / drug effects; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Molecular Structure; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Staphylococcus epidermidis / drug effects; Structure-Activity Relationship
TL;DR: These molecules, previously underexplored as antibacterial agents, serve as a new scaffold for antimicrobial development. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2018

2018 journal article

Three-Dimensional Heterogeneous Structure Formation on a Supported Lipid Bilayer Disclosed by Single-Particle Tracking

LANGMUIR, 34(39), 11857–11865.

By: Y. Zhong n & G. Wang n

MeSH headings : Diffusion; Hydrogen-Ion Concentration; Lipid Bilayers / chemistry; Nanoparticles / chemistry; Phosphatidylethanolamines / chemistry; Phosphatidylserines / chemistry; Polystyrenes / chemistry; Surface Properties
TL;DR: This work suggests that the geometry of the 3D lipid structures can play a role in tuning the particle-lipid surface interactions, and sheds new light on the origin of lateral heterogeneity on the lipid membrane. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2018

2018 journal article

Effect of doping Ge into Y2O3:Ho,Yb on the green-to-red emission ratio and temperature sensing

DALTON TRANSACTIONS, 47(32), 11158–11165.

By: V. Kumar n, B. Zoellner n, P. Maggard n & G. Wang n

TL;DR: This study demonstrates a new mechanism to channel non-thermally coupled energy levels to achieve high temperature sensitivity and matched green and red emission intensities, as well as the high thermal sensitivity, in Y2O3:Ho,Yb,Ge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018

2018 journal article

Tuning the Redox Potentials and Ligand Field Strength of Fe(II) Polypyridines: The Dual pi-Donor and pi-Acceptor Character of Bipyridine

INORGANIC CHEMISTRY, 57(16), 9907–9917.

By: D. Ashley n & E. Jakubikova n

TL;DR: Overall, substituent modification is a useful strategy for fine-tuning the ligand field strength but not for significant reordering of the spin-state manifold, despite the large effect on metal-ligand electrostatic interactions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 19, 2018

2018 journal article

Amphiphile self-assembly dynamics at the solution-solid interface reveal asymmetry in head/tail desorption

CHEMICAL COMMUNICATIONS, 54(72), 10076–10079.

By: H. Castillo*, J. Espinosa-Duran*, J. Dobscha*, D. Ashley*, S. Debnath*, B. Hirsch*, S. Schrecke*, M. Baik* ...

TL;DR: Molecular dynamics simulations reveal asymmetry in desorption-adsorption steps and discover Desorption starting from alkyl chain detachment from the surface is favored due to dynamic occlusion by neighbouring chains. (via Semantic Scholar)
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Nonequivalent Spin Exchanges of the Hexagonal Spin Lattice Affecting the Low-Temperature Magnetic Properties of RInO3 (R = Gd, Tb, Dy): Importance of Spin-Orbit Coupling for Spin Exchanges between Rare-Earth Cations with Nonzero Orbital Moments

INORGANIC CHEMISTRY, 57(15), 9260–9265.

TL;DR: DFT calculations for RInO3 carried out to explore if their low-temperature magnetic properties are related to the two nonequivalent nearest-neighbor (NN) spin exchanges of their hexagonal spin lattices predict that the orbital moments of the Tb3+ and Dy3+ ions are smaller than their free-ion values by ∼2μB while the T b3+ spins have an in-plane magnetic anisotropy, in agreement with the experiments. (via Semantic Scholar)
Source: Web Of Science
Added: October 16, 2018

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