Works Published in 2014

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Displaying works 141 - 160 of 200 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 journal article

Progression of Gene Expression Changes following a Mechanical Injury to Articular Cartilage as a Model of Early Stage Osteoarthritis

Arthritis, 2014, 1–9.

By: R. McCulloch n, M. Ashwell n, C. Maltecca n, A. O'Nan n & P. Mente n

TL;DR: Changes in differential gene expression suggest that the more physiologically relevant shear loading may initially be more damaging to the cartilage and induces more repair efforts after loading. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019

2014 journal article

Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

Cell Metabolism, 19(4), 682–693.

By: J. Qiu*, C. Zhang*, A. Borgquist*, C. Nestor*, A. Smith*, M. Bosch*, S. Ku*, E. Wagner*, O. Rønnekleiv*, M. Kelly*

MeSH headings : Agouti-Related Protein / metabolism; Animals; Eating / drug effects; Guinea Pigs; Insulin / pharmacology; KATP Channels / drug effects; Kisspeptins / metabolism; Mice; Models, Biological; Neurons / drug effects; Neurons / metabolism; Neuropeptide Y / metabolism; Patch-Clamp Techniques; Pro-Opiomelanocortin / metabolism; Proto-Oncogene Proteins c-fos / metabolism; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / physiology; Transient Receptor Potential Channels / metabolism; Zinc / pharmacology
TL;DR: The results show that purified insulin excites POMC neurons in the arcuate nucleus, which is a major mechanism by which insulin regulates energy homeostasis. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 24, 2019

2014 journal article

Research Resource: Gene Profiling of G Protein–Coupled Receptors in the Arcuate Nucleus of the Female

Molecular Endocrinology, 28(8), 1362–1380.

By: O. Rønnekleiv*, Y. Fang*, C. Zhang*, C. Nestor*, P. Mao* & M. Kelly*

MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / cytology; Arcuate Nucleus of Hypothalamus / metabolism; Cells, Cultured; Female; Gene Expression Profiling; Mice, Inbred C57BL; Neurons / metabolism; Pro-Opiomelanocortin / metabolism; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Transcriptome
TL;DR: The quantitative GPCR data emphasize the complexity of the hypothalamic arcuate nucleus and furthermore provide a valuable resource for future neuroendocrine/endocrine-related experiments. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 23, 2019

2014 journal article

Neurokinin-3 Receptor Activation in the Retrochiasmatic Area is Essential for the Full Pre-Ovulatory Luteinising Hormone Surge in Ewes

Journal of Neuroendocrinology, 26(11), 776–784.

By: K. Porter*, S. Hileman*, S. Hardy*, C. Nestor*, M. Lehman* & R. Goodman*

author keywords: neurokinins; GnRH; oestrogen; NK3R; LH surge
MeSH headings : Animals; Arcuate Nucleus of Hypothalamus / drug effects; Arcuate Nucleus of Hypothalamus / metabolism; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Luteinizing Hormone / blood; Neurons / drug effects; Neurons / metabolism; Ovulation / drug effects; Ovulation / metabolism; Peptide Fragments / pharmacology; Preoptic Area / drug effects; Preoptic Area / metabolism; Quinolines / pharmacology; Receptors, Neurokinin-3 / agonists; Receptors, Neurokinin-3 / antagonists & inhibitors; Receptors, Neurokinin-3 / metabolism; Sheep; Substance P / analogs & derivatives; Substance P / pharmacology
TL;DR: It is proposed that the actions of NKB in the RCh are an important component of the pre‐ovulatory LH surge in ewes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: November 23, 2019

2014 journal article

Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signaling

Hormone Molecular Biology and Clinical Investigation, 17(3).

By: C. Nestor*, M. Kelly & O. Rønnekleiv

author keywords: 17 beta-estradiol; kisspeptin; leptin; neuropeptide Y; pro-opiomelanocortin
MeSH headings : Animals; Energy Metabolism; Estradiol / metabolism; Estrogens / metabolism; Homeostasis; Humans; Kisspeptins / metabolism; Leptin / metabolism; Neurons / metabolism; Neuropeptide Y / metabolism; Phosphorylation; Pro-Opiomelanocortin / metabolism; Reproduction; STAT3 Transcription Factor / metabolism; Signal Transduction
TL;DR: Progress made in understanding the interactions between reproduction and energy homeostasis is reviewed by focusing on the advances made to understand the cellular signaling of E2 and leptin on three neural networks: kisspeptin, pro-opiomelanocortin (POMC) and neuropeptide Y (NPY). (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: November 23, 2019

2014 personal communication

Experience of breathing carbon dioxide Response

By: R. Meyer, W. Morrow, L. Stikeleather & D. Styles

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

The Effect of Feeding Two or Three Meals Per Day of Either Low or High Nonstructural Carbohydrate Concentrates on Postprandial Glucose and Insulin Concentrations in Horses

JOURNAL OF EQUINE VETERINARY SCIENCE, 34(11-12), 1251–1256.

By: S. Pratt-Phillips n, J. Kutzner-Mulligan n, R. Marvin n, H. Brown n, C. Sykes n & J. Federico n

author keywords: Equine; Nonstructural carbohydrate; Insulin
TL;DR: It is suggested that NSC content of a concentrate feed has an impact on baseline insulin and GIRs and on postprandial insulin concentrations, while the number (and therefore size) of MPD had fewer impacts on glucose metabolism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Protective Effect of Two Yeast Based Feed Additives on Pigs Chronically Exposed to Deoxynivalenol and Zearalenone

Toxins, 6(12), 3336–3353.

By: A. Weaver n, M. See n & S. Kim n

Contributors: A. Weaver n, M. See n & S. Kim n

author keywords: deoxynivalenol; feed additives; pigs; yeast; zearalenone
MeSH headings : Animal Feed / analysis; Animal Feed / microbiology; Animals; Food Contamination / analysis; Food Microbiology; Liver / drug effects; Oxidative Stress / drug effects; Saccharomyces cerevisiae / metabolism; Swine; Trichothecenes / administration & dosage; Trichothecenes / toxicity; Zearalenone / administration & dosage; Zearalenone / toxicity
TL;DR: Collectively, feeding diets contaminated with mycotoxins significantly reduced growth performance and impacted pig health, and the yeast additives had varied ability to reduce mycotoxin effects on pig growth and health, but may still play a beneficial role in reducing the overall impacts of aMycotoxin challenge on pigs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Genetic parameters for milk yield and persistency in Carora dairy cattle breed using random regression model

ITALIAN JOURNAL OF ANIMAL SCIENCE, 13(4).

author keywords: Random regression models; Persistency; Dairy cattle; Tropics; Carora breed
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Fecal microbial diversity and putative function in captive western lowland gorillas (Gorilla gorilla gorilla), common chimpanzees (Pan troglodytes), Hamadryas baboons (Papio hamadryas) and binturongs (Arctictis binturong)

INTEGRATIVE ZOOLOGY, 9(5), 557–569.

By: E. McKenney n, M. Ashwell n, J. Lambert* & V. Fellner n

author keywords: ecology; fermentation; gastrointestinal microbiota; microbial diversity
MeSH headings : Animals; Bacteria / classification; Bacteria / isolation & purification; Dietary Fiber; Feces / microbiology; Fermentation; Gorilla gorilla / microbiology; Pan troglodytes / microbiology; Papio hamadryas / microbiology; Phylogeny; Sequence Analysis, DNA; Species Specificity; Viverridae / microbiology
TL;DR: Eubacterial profiles were consistent with fermentation data and suggest an increase in diversity with dietary fiber in gorillas, common chimpanzees, Hamadryas baboons and binturongs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Blocking Ligand Occupancy of the alpha V beta 3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs

ENDOCRINOLOGY, 155(12), 4665–4675.

By: L. Maile*, W. Busby*, K. Gollahon*, W. Flowers n, N. Garbacik n, S. Garbacik n, K. Stewart n, T. Nichols* ...

MeSH headings : Animals; Antibodies, Monoclonal; Diabetic Nephropathies / etiology; Diabetic Nephropathies / metabolism; Diabetic Nephropathies / pathology; Glomerular Basement Membrane / pathology; Integrin alphaVbeta3 / antagonists & inhibitors; Integrin alphaVbeta3 / metabolism; Male; Mice, Inbred BALB C; Podocytes / pathology; Proteinuria / etiology; Swine
TL;DR: Administration of an antibody that inhibits activation of the β3-subunit of αVβ3 that is induced by hyperglycemia attenuates proteinuria and early histologic changes of diabetic nephropathy, suggesting that it may have utility in preventing the progression of this disease complication. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 article

Evaluation of carbon dioxide administration for on-site mass depopulation of swine in response to animal health emergencies

Meyer, R. E., Morrow, W. E. M., Stikeleather, L. F., Baird, C. L., Rice, J. M., Byrne, H., … Styles, D. K. (2014, April 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 244, pp. 924–933.

By: R. Meyer n, W. Morrow n, L. Stikeleather n, C. Baird n, J. Rice n, H. Byrne n, B. Halbert n, D. Styles n

MeSH headings : Animal Welfare; Animals; Carbon Dioxide; Emergencies / veterinary; Euthanasia, Animal / methods; Swine; Swine Diseases / prevention & control; Time Factors
TL;DR: Mass depopulation refers to methods by which large numbers of animals must be destroyed quickly and efficiently with as much consideration given to the welfare of the animals as practicable, but where the circumstances and tasks facing those performing depopu-lation are understood to be extenuating. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Amino acid fortified diets for weanling pigs replacing fish meal and whey protein concentrate: Effects on growth, immune status, and gut health

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY, 5(1).

By: Y. Zhao n, A. Weaver n, V. Fellner n, R. Payne & S. Kim n

Contributors: Y. Zhao n, A. Weaver n, V. Fellner n, R. Payne & S. Kim n

author keywords: Amino acid; Fish meal; Growth performance; Pig; Whey protein concentrate
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

The effect of breed and sex on sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine pharmacokinetic parameters in swine

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 37(6), 531–541.

Contributors: J. Howard n, R. Baynes n, J. Brooks n, J. Yeatts n, B. Bellis n, M. Ashwell n, P. Routh n, . A.T. O'Nan n, C. Maltecca n

MeSH headings : Animals; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Anti-Inflammatory Agents, Non-Steroidal / blood; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Antinematodal Agents / blood; Antinematodal Agents / pharmacokinetics; Benzimidazoles / blood; Ciprofloxacin / blood; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Enrofloxacin; Female; Fenbendazole / blood; Fenbendazole / pharmacokinetics; Fluoroquinolones / blood; Fluoroquinolones / pharmacokinetics; Male; Sex Factors; Species Specificity; Sulfamethazine / analogs & derivatives; Sulfamethazine / blood; Sulfamethazine / pharmacokinetics; Swine / metabolism
TL;DR: Whether drug clearance differs across genetic backgrounds and sex for sulfamethazine, enrofloxacin, fenbendazole and flunixin meglumine is determined to determine the degree of additive genetic variation utilizing a larger population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Serum Leptin as an Indicator of Fat Levels in White-tailed Deer (Odocoileus virginianus) in the Southeastern USA

JOURNAL OF WILDLIFE DISEASES, 50(4), 887–890.

author keywords: Body fat; fat index; leptin; Odocoileus virginianus; white-tailed deer
MeSH headings : Adipose Tissue / physiology; Animals; Deer / blood; Deer / physiology; Female; Leptin / blood; Pregnancy; Southeastern United States
TL;DR: Serum leptin concentrations were similar between seasons but were lower in lactating and gestating females, indicating that leptin may have limited value for estimating fat reserves in white-tailed deer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Effects of phytase supplementation on reproductive performance, apparent total tract digestibility of Ca and P and bone characteristics in gestating and lactating sows

Revista Colombiana De Ciencias Pecuarias, 27(3), 178–193.

By: Y. Dal Jang, M. Lindemann, E. Heugten, R. Jones, B. Kim, C. Maxwell, J. Radcliffe

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Effects of Chitosan on Intestinal Inflammation in Weaned Pigs Challenged by Enterotoxigenic Escherichia coli

PLoS ONE, 9(8), e104192.

By: D. Xiao*, Y. Wang, G. Liu*, J. He*, W. Qiu*, X. Hu*, Z. Feng, M. Ran* ...

Contributors: D. Xiao*, Y. Wang, G. Liu*, J. He*, W. Qiu*, X. Hu*, Z. Feng, M. Ran* ...

Ed(s): D. Chakravortty

MeSH headings : Animals; Chitosan / administration & dosage; Diarrhea / drug therapy; Diarrhea / veterinary; Enterotoxigenic Escherichia coli / drug effects; Enterotoxigenic Escherichia coli / pathogenicity; Gene Expression / drug effects; Immunity, Cellular / drug effects; Inflammation / drug therapy; Inflammation / microbiology; Inflammation / veterinary; Intestines / drug effects; Intestines / microbiology; Intestines / pathology; Leukocyte L1 Antigen Complex; Swine; Toll-Like Receptor 4 / biosynthesis; Tumor Necrosis Factor-alpha / biosynthesis; Weaning
TL;DR: Results indicate that supplementation with COS at 300 mg/kg was effective for alleviating intestinal inflammation and enhancing the cell-mediated immune response and as feed additives, chitosan and chlortetracycline may influence different mechanisms for alleviated inflammation in piglets. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Effect of gonadotropin releasing factor suppression with an immunological on growth performance, estrus activity, carcass characteristics, and meat quality of market gilts

JOURNAL OF ANIMAL SCIENCE, 92(10), 4719–4724.

By: B. Bohrer*, W. Flowers n, J. Kyle*, S. Johnson*, V. King*, J. Spruill*, D. Thompson*, A. Schroeder*, D. Boler*

author keywords: estrus suppression; gilt; gonadotropin releasing factor; Improvest
MeSH headings : Animals; Body Composition / drug effects; Body Weight / physiology; Estrus; Female; Gonadotropin-Releasing Hormone / pharmacology; Meat / standards; Sexual Maturation / drug effects; Swine / physiology
TL;DR: Data suggest market gilts treated with an anti-GnRF analog had suppressed estrus and episodical changes in ADFI, while they had improved feed efficiency, increased ADG, and increased back fat depth when compared with gilts without anAnti-GNRF analog treatment. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Dietary Calcium Deficiency and Excess Both Impact Bone Development and Mesenchymal Stem Cell Lineage Priming in Neonatal Piglets

JOURNAL OF NUTRITION, 144(12), 1935–1942.

By: Y. Li n & C. Stahl n

author keywords: calcium; swine; mesenchymal stem cells; neonate; differentiation potential
MeSH headings : Adipocytes / drug effects; Animals; Animals, Newborn; Bone Development / drug effects; Calcium / deficiency; Calcium, Dietary / administration & dosage; Calcium, Dietary / blood; Cell Differentiation / drug effects; Cell Lineage / drug effects; Creatinine / urine; Diet; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins / genetics; Fatty Acid-Binding Proteins / metabolism; Female; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Osteocalcin / genetics; Osteocalcin / metabolism; Osteogenesis / drug effects; PPAR gamma / genetics; PPAR gamma / metabolism; Parathyroid Hormone / blood; RNA, Messenger / genetics; RNA, Messenger / metabolism; Swine
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Abdominal lipomatosis with secondary self-strangulation of masses in an adult rhesus macaque (Macaca mulatta)

Comparative Medicine, 64(5), 404–408.

By: H. Chum, C. Long, G. McKeon, A. Chang, R. Luong & M. Albertelli

Source: NC State University Libraries
Added: August 6, 2018

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