Works (25)

Updated: July 5th, 2023 15:44

2021 review

Surface distribution of pyrethroids following topical application to veterinary species: Implications for lateral transport

[Review of ]. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 44(1), 1–10.

By: W. Baeumer & R. Baynes n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: lateral transport; pyrethroids
MeSH headings : Administration, Topical; Animals; Animals, Domestic; Ectoparasitic Infestations / drug therapy; Ectoparasitic Infestations / veterinary; Insecticides / administration & dosage; Insecticides / therapeutic use; Pyrethrins / administration & dosage; Pyrethrins / therapeutic use
Source: Web Of Science
Added: September 28, 2020

2021 journal article

TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch

BIOMOLECULES, 11(8).

By: J. Wilzopolski n, M. Kietzmann*, S. Mishra n, H. Stark*, W. Baeumer & K. Rossbach*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: histamine; histamine H1 receptor; histamine H4 receptor; itch; signal transduction; TRPV1; TRPA1; dorsal root ganglion neurons (DRG); Ca2+-imaging
MeSH headings : Acetanilides / pharmacology; Animals; Calcium / metabolism; Capsaicin / analogs & derivatives; Capsaicin / pharmacology; Female; Ganglia, Spinal / drug effects; Ganglia, Spinal / metabolism; Gene Expression; Histamine / administration & dosage; Male; Methylhistamines / administration & dosage; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Molecular Imaging; Primary Cell Culture; Pruritus / chemically induced; Pruritus / drug therapy; Pruritus / genetics; Pruritus / metabolism; Purines / pharmacology; Ruthenium Red / pharmacology; Sensory Receptor Cells / drug effects; Sensory Receptor Cells / metabolism; Signal Transduction; TRPA1 Cation Channel / antagonists & inhibitors; TRPA1 Cation Channel / genetics; TRPA1 Cation Channel / metabolism; TRPV Cation Channels / antagonists & inhibitors; TRPV Cation Channels / genetics; TRPV Cation Channels / metabolism
Source: Web Of Science
Added: September 7, 2021

2020 journal article

Draft Genome Sequence of Staphylococcus pseudintermedius Strain 13-13613, Isolated from a Case of Canine Pyoderma

MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(7).

By: I. Eichhorn*, A. Luebke-Becker, A. Lapschies*, M. Jacob n, W. Baeumer & M. Fulde*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
Source: Web Of Science
Added: March 10, 2020

2020 journal article

Efficacy study of a topical treatment with a plant extract with antibiofilm activities using an in vivo model of canine superficial pyoderma

VETERINARY DERMATOLOGY, 31(2), 86–89.

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Administration, Topical; Animals; Anti-Bacterial Agents / administration & dosage; Biofilms / drug effects; Cross-Over Studies; Disease Models, Animal; Dog Diseases / drug therapy; Dogs; Female; Male; Microbial Sensitivity Tests; Plant Extracts / administration & dosage; Proof of Concept Study; Pyoderma / drug therapy; Pyoderma / veterinary; Skin / microbiology; Skin / pathology; Staphylococcus / drug effects
Source: Web Of Science
Added: December 2, 2019

2020 journal article

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

CELL REPORTS, 31(1).

By: S. Mishra n, J. Wheeler n, S. Pitake n, H. Ding*, C. Jiang*, T. Fukuyama n, J. Paps n, P. Ralph n ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸

Contributors: S. Mishra n, J. Wheeler n, S. Pitake n, H. Ding*, C. Jiang*, T. Fukuyama n, J. Paps n, P. Ralph n ...

MeSH headings : Animals; Cell Adhesion Molecules / metabolism; Cell Adhesion Molecules / physiology; Dermatitis, Atopic / etiology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Dogs; Female; Hypersensitivity / physiopathology; Integrin alpha5 / metabolism; Integrin beta3 / metabolism; Integrins / metabolism; Keratinocytes / metabolism; Male; Mice; Primates; Pruritus / metabolism; Pruritus / pathology; Sensory Receptor Cells / metabolism; Skin / metabolism
Sources: Web Of Science, ORCID
Added: April 27, 2020

2019 journal article

Diphenhydramine pharmacokinetics after oral and intravenous administration of diphenhydramine and oral administration of dimenhydrinate to healthy dogs, and pharmacodynamic effect on histamine-induced wheal formation: a pilot study

VETERINARY DERMATOLOGY, 30(2), 91-+.

By: S. Ehling n, W. Baeumer & M. Papich n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Administration, Intravenous; Administration, Oral; Animals; Cross-Over Studies; Dimenhydrinate / administration & dosage; Dimenhydrinate / blood; Dimenhydrinate / pharmacokinetics; Diphenhydramine / administration & dosage; Diphenhydramine / blood; Diphenhydramine / pharmacokinetics; Dogs; Female; Half-Life; Histamine / adverse effects; Histamine Antagonists / pharmacokinetics; Male; Pilot Projects; Theophylline / blood; Urticaria / chemically induced; Urticaria / drug therapy
Sources: Web Of Science, ORCID
Added: April 2, 2019

2018 journal article

Comparison of topical tofacitinib and 0.1% hypochlorous acid in a murine atopic dermatitis model

BMC PHARMACOLOGY & TOXICOLOGY, 19.

By: T. Fukuyama n, S. Ehling n, J. Wilzopolski n & W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Atopic dermatitis; Dorsal root ganglia; Hypochlorous acid; Tofacitinib; IgE; IL-4; IL-13; NC/Nga mice; Sensory neurons
MeSH headings : Administration, Topical; Animals; Cells, Cultured; Cytokines / immunology; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Disease Models, Animal; Female; Ganglia, Spinal / cytology; Hypochlorous Acid / therapeutic use; Immunoglobulin E / blood; Mice; Neurons / drug effects; Neurons / immunology; Piperidines / therapeutic use; Protein Kinase Inhibitors / therapeutic use; Pyrimidines / therapeutic use; Pyrroles / therapeutic use; Skin / drug effects; Skin / immunology
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Hypochlorous acid is antipruritic and anti-inflammatory in a mouse model of atopic dermatitis

CLINICAL AND EXPERIMENTAL ALLERGY, 48(1), 78–88.

By: T. Fukuyama n, B. Martel n, K. Linder n, S. Ehling n, J. Ganchingco n & W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: atopic dermatitis; dorsal root ganglia; hypochlorous acid; IgE; IL-13; IL-4; NC; Nga mice; sensory neurons
MeSH headings : Animals; Anti-Inflammatory Agents / pharmacology; Antigens, Dermatophagoides / toxicity; Antipruritics / pharmacology; Cytokines / immunology; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / pathology; Disease Models, Animal; Female; Hypochlorous Acid / pharmacology; Inflammation / chemically induced; Inflammation / drug therapy; Inflammation / immunology; Inflammation / pathology; Mice; Mice, Inbred BALB C
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Impact of synthetic canine cerumen on in vitro penetration of auricular skin of dogs by florfenicol, terbinafine, and betamethasone acetate

AMERICAN JOURNAL OF VETERINARY RESEARCH, 79(3), 333–341.

By: S. Ehling, R. Baynes* & W. Baeumer

MeSH headings : Administration, Cutaneous; Animals; Betamethasone / pharmacokinetics; Cerumen / chemistry; Chromatography, High Pressure Liquid / veterinary; Dogs / metabolism; Female; Gels; Male; Naphthalenes / pharmacokinetics; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Terbinafine; Thiamphenicol / analogs & derivatives; Thiamphenicol / pharmacokinetics
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Janus kinase inhibitors differ in their affinity to the TRPV1 receptor - implications for their use in itch and pain

Journal of Veterinary Pharmacology and Therapeutics, 41, 160–160.

By: L. Sanabria-Ojeda, T. Fukuyama, D. Fourches & W. Baumer

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Neuromedin B: Characterization of a novel peripheral pruritogen

Journal of Veterinary Pharmacology and Therapeutics, 41, 48–48.

By: S. Ehling, M. Ko, T. Fukuyama, T. Olivry & W. Baumer

Source: NC State University Libraries
Added: August 6, 2018

2017 personal communication

Janus kinase inhibitors display broad anti-itch properties: A possible link through the TRPV1 receptor

Fukuyama, T., Ganchingco, J. R., Mishra, S. K., Olivry, T., Rzagalinski, I., Volmer, D. A., & Baeumer, W. (2017, July).

By: T. Fukuyama n, J. Ganchingco n, S. Mishra n, T. Olivry n, I. Rzagalinski*, D. Volmer*, W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸

Contributors: T. Fukuyama n, J. Ganchingco n, S. Mishra n, T. Olivry n, I. Rzagalinski*, D. Volmer*, W. Bäumer n

MeSH headings : Animals; Antipruritics / chemistry; Antipruritics / pharmacology; Dopaminergic Neurons / drug effects; Dopaminergic Neurons / metabolism; Female; Humans; Janus Kinase Inhibitors / chemistry; Janus Kinase Inhibitors / pharmacology; Mice; Models, Molecular; Molecular Conformation; Molecular Imaging / methods; Protein Binding; Sensory Receptor Cells / drug effects; Sensory Receptor Cells / metabolism; Structure-Activity Relationship; TRPV Cation Channels / antagonists & inhibitors; TRPV Cation Channels / chemistry; TRPV Cation Channels / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Nocifensive Behaviors in Mice with Radiation-Induced Oral Mucositis

RADIATION RESEARCH, 187(3), 397–403.

By: M. Nolan*, C. Long, K. Marcus*, S. Sarmadi, D. Roback*, T. Fukuyama*, W. Baeumer*, B. Lascelles

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Behavior, Animal / radiation effects; Mice; Neurons / pathology; Neurons / radiation effects; Nociception / radiation effects; Radiation Injuries, Experimental / pathology; Radiation Injuries, Experimental / physiopathology; Stomatitis / pathology; Stomatitis / physiopathology; Trigeminal Ganglion / pathology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Allergic inflammation is augmented via histamine H4 receptor activation: The role of natural killer cells in vitro and in vivo

JOURNAL OF DERMATOLOGICAL SCIENCE, 83(2), 106–115.

By: S. Ehling n, K. Rossbach*, S. Dunston n, H. Stark* & W. Baumer n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Natural killer cells; Histamine H4 receptor; CCL17/TARC; Dermal dendritic cells; Allergic contact dermatitis
MeSH headings : Animals; Chemokine CCL17 / metabolism; Chemotaxis / drug effects; Coculture Techniques; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Atopic / immunology; Dermatitis, Atopic / metabolism; Disease Models, Animal; Female; Histamine / metabolism; Humans; Indoles / pharmacology; Killer Cells, Natural / drug effects; Killer Cells, Natural / metabolism; Mice; Mice, Inbred BALB C; Mice, Knockout; Ovalbumin; Piperazines / pharmacology; Pyrimidines / pharmacology; Receptors, G-Protein-Coupled / agonists; Receptors, G-Protein-Coupled / antagonists & inhibitors; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Receptors, Histamine / genetics; Receptors, Histamine / metabolism; Receptors, Histamine H4; Skin / cytology; Skin / drug effects; Skin / metabolism; Toluene 2,4-Diisocyanate / toxicity
Source: Web Of Science
Added: August 6, 2018

2016 article

Development of an Allergen-induced Atopic Itch Model in Dogs: A Preliminary Report

ACTA DERMATO-VENEREOLOGICA, Vol. 96, pp. 400–401.

By: J. Paps*, W. Baeumer & T. Olivry*

Contributors: J. Paps*, W. Bäumer & T. Olivry*

MeSH headings : Animals; Anti-Allergic Agents / pharmacology; Antigens, Dermatophagoides; Behavior, Animal; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / immunology; Dermatitis, Atopic / psychology; Disease Models, Animal; Dogs; Glucocorticoids / pharmacology; Motor Activity; Prednisolone / pharmacology; Pruritus / drug therapy; Pruritus / immunology; Pruritus / psychology; Reproducibility of Results; Time Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis

ALLERGY, 71(2), 189–197.

By: K. Rossbach*, K. Schaper*, C. Kloth*, R. Gutzmer*, T. Werfel*, M. Kietzmann*, W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Allergic inflammation; atopic dermatitis; histamine H4 receptor; OVA
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cytokines / biosynthesis; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / etiology; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Disease Models, Animal; Epidermis / immunology; Epidermis / metabolism; Epidermis / pathology; Female; Immunoglobulin E / immunology; Lymph Nodes / immunology; Lymph Nodes / metabolism; Mice; Mice, Knockout; Ovalbumin / adverse effects; Piperidines / pharmacology; Pyridines / pharmacology; Receptors, G-Protein-Coupled / antagonists & inhibitors; Receptors, G-Protein-Coupled / deficiency; Receptors, G-Protein-Coupled / genetics; Receptors, Histamine / deficiency; Receptors, Histamine / genetics; Receptors, Histamine H4; Skin / immunology; Skin / metabolism; Skin / pathology
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Topically applied manganese-porphyrins BMX-001 and BMX-010 display a significant anti-inflammatory response in a mouse model of allergic dermatitis

ARCHIVES OF DERMATOLOGICAL RESEARCH, 308(10), 711–721.

By: K. Stover n, T. Fukuyama n, A. Young n, M. Daniele n, R. Oberley*, J. Crapo*, W. Baeumer

co-author countries: United States of America 🇺🇸
author keywords: Superoxide dismutase mimics; BMX-010; BMX-001; Allergic dermatitis; Mice
MeSH headings : Administration, Cutaneous; Administration, Oral; Animals; Cell Line; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Dermatitis, Allergic Contact / drug therapy; Disease Models, Animal; Ear; Female; Humans; Infant, Newborn; Inflammation / drug therapy; Inflammation / metabolism; Interleukin-1beta / metabolism; Interleukin-4 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Metalloporphyrins / administration & dosage; Metalloporphyrins / therapeutic use; Mice; Mice, Inbred BALB C; Pruritus / drug therapy; Skin / drug effects; Skin / metabolism; Skin Cream; Superoxide Dismutase / metabolism; Toluene 2,4-Diisocyanate / toxicity; p-Methoxy-N-methylphenethylamine / toxicity
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Aggression behaviour induced by oral administration of the Janus-kinase inhibitor tofacitinib, but not oclacitinib, under stressful conditions

European Journal of Pharmacology, 764, 278–282.

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Administration, Oral; Aggression / drug effects; Animals; Anti-Allergic Agents / adverse effects; Anti-Allergic Agents / pharmacokinetics; Anti-Allergic Agents / therapeutic use; Anti-Inflammatory Agents / adverse effects; Anti-Inflammatory Agents / pharmacokinetics; Anti-Inflammatory Agents / therapeutic use; Behavior, Animal / drug effects; Brain / metabolism; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / drug therapy; Dermatitis, Atopic / metabolism; Disease Models, Animal; Female; Janus Kinases / antagonists & inhibitors; Janus Kinases / metabolism; Male; Mice, Inbred BALB C; Piperidines / adverse effects; Piperidines / pharmacokinetics; Piperidines / therapeutic use; Protein Kinase Inhibitors / adverse effects; Protein Kinase Inhibitors / pharmacokinetics; Protein Kinase Inhibitors / therapeutic use; Pruritus / chemically induced; Pruritus / drug therapy; Pruritus / metabolism; Pyrimidines / adverse effects; Pyrimidines / pharmacokinetics; Pyrimidines / therapeutic use; Pyrroles / adverse effects; Pyrroles / pharmacokinetics; Pyrroles / therapeutic use; Stress, Psychological; Sulfonamides / pharmacokinetics; Sulfonamides / therapeutic use; Toluene 2,4-Diisocyanate
Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Effects of azathioprine, 6-mercaptopurine, and 6-thioguanine on canine primary hepatocytes

AMERICAN JOURNAL OF VETERINARY RESEARCH, 76(7), 649–655.

By: K. LaDuke, S. Ehling*, J. Cullen* & W. Baeumer

MeSH headings : Animals; Azathioprine / administration & dosage; Azathioprine / pharmacology; Cell Line; Cell Survival / drug effects; Dogs; Dose-Response Relationship, Drug; Hepatocytes / drug effects; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / pharmacology; Mercaptopurine / administration & dosage; Mercaptopurine / pharmacology; Thioguanine / administration & dosage; Thioguanine / pharmacology
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Topically Administered Janus-Kinase Inhibitors Tofacitinib and Oclacitinib Display Impressive Antipruritic and Anti-Inflammatory Responses in a Model of Allergic Dermatitis

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 354(3), 394–405.

By: T. Fukuyama n, S. Ehling n, E. Cook n & W. Baeumer

co-author countries: United States of America 🇺🇸
MeSH headings : Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents / administration & dosage; Antipruritics / administration & dosage; Cytokines / metabolism; Dermatitis, Allergic Contact / drug therapy; Dermatitis, Allergic Contact / metabolism; Disease Models, Animal; Female; Inflammation / drug therapy; Inflammation / metabolism; Janus Kinases / antagonists & inhibitors; Lymph Nodes / drug effects; Lymph Nodes / metabolism; Mice; Mice, Inbred BALB C; Piperidines / administration & dosage; Pruritus / drug therapy; Pruritus / metabolism; Pyrimidines / administration & dosage; Pyrroles / administration & dosage; Skin / drug effects; Skin / metabolism; Sulfonamides / administration & dosage
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Vaccination of calves with yeast- and bacterial-expressed paramyosin from the bovine lungworm Dictyocaulus viviparus

PARASITE IMMUNOLOGY, 37(12), 614–623.

By: D. Joekel*, P. Hinse*, M. Raulf*, S. Schicht*, W. Baeumer, D. Werling*, E. Kremmer*, C. Strube*

co-author countries: Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: bovine lungworm; Dictyocaulus viviparus; immunization; nematode; paramyosin; vaccine
MeSH headings : Animals; Antibodies, Helminth / immunology; Antigens, Helminth / genetics; Antigens, Helminth / immunology; Cattle; Cattle Diseases / prevention & control; Dictyocaulus / immunology; Dictyocaulus Infections / prevention & control; Escherichia coli / genetics; Escherichia coli / metabolism; Female; Helminth Proteins / genetics; Helminth Proteins / immunology; Immunoglobulin G / immunology; Larva; Leukocytes, Mononuclear / immunology; Male; Recombinant Proteins; Tropomyosin / genetics; Tropomyosin / immunology; Vaccination / veterinary; Vaccines / immunology; Yeasts / genetics; Yeasts / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

PCR detects bands consistent with the expression of receptors associated with pruritus in canine dorsal root ganglia

VETERINARY DERMATOLOGY, 25(1), 9-+.

By: K. Rossbach* & W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Animals; Dog Diseases / etiology; Dogs; Ganglia, Spinal / metabolism; Gene Expression Regulation / physiology; Pruritus / genetics; Pruritus / metabolism; Pruritus / veterinary; RNA / genetics; RNA / metabolism; Receptor, Endothelin A / genetics; Receptor, Endothelin A / metabolism; Receptors, Histamine / genetics; Receptors, Histamine / metabolism; Receptors, Interleukin / genetics; Receptors, Interleukin / metabolism; Receptors, Neurokinin-1 / genetics; Receptors, Neurokinin-1 / metabolism; Receptors, Opioid / genetics; Receptors, Opioid / metabolism; Reverse Transcriptase Polymerase Chain Reaction / veterinary; TRPV Cation Channels / genetics; TRPV Cation Channels / metabolism; Toll-Like Receptor 7 / genetics; Toll-Like Receptor 7 / metabolism
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Sphingosine-1-phosphate differently regulates the cytokine production of IL-12, IL-23 and IL-27 in activated murine bone marrow derived dendritic cells

MOLECULAR IMMUNOLOGY, 59(1), 10–18.

By: K. Schaper*, M. Kietzmann* & W. Baeumer

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Sphingosine-1-phosphate; Dendritic cells; IL-12; IL-23; IL-27; MAPK
MeSH headings : Androstadienes / pharmacology; Animals; Bone Marrow Cells / cytology; Bone Marrow Cells / drug effects; Bone Marrow Cells / metabolism; Cells, Cultured; Dendritic Cells / cytology; Dendritic Cells / drug effects; Dendritic Cells / metabolism; Enzyme Inhibitors / pharmacology; Gene Expression / drug effects; Immunoblotting; Interleukin-12 / biosynthesis; Interleukin-23 / biosynthesis; Interleukin-27 / biosynthesis; Lipopolysaccharides / pharmacology; Lysophospholipids / pharmacology; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases / antagonists & inhibitors; Mitogen-Activated Protein Kinases / metabolism; Oxadiazoles / pharmacology; Phosphatidylinositol 3-Kinases / metabolism; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation / drug effects; Pyrazoles / pharmacology; Pyridines / pharmacology; Receptors, Lysosphingolipid / agonists; Receptors, Lysosphingolipid / antagonists & inhibitors; Receptors, Lysosphingolipid / genetics; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / drug effects; Sphingosine / analogs & derivatives; Sphingosine / pharmacology; Thiophenes / pharmacology; Wortmannin; p38 Mitogen-Activated Protein Kinases / antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases / metabolism
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Pharmacokinetics and thrombolytic effects of the recombinant tissue-type plasminogen activator in horses

BMC VETERINARY RESEARCH, 9.

By: W. Baeumer, G. Herrling* & K. Feige*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Alteplase; Recombinant tissue plasminogen activator; Thrombus; Clot formation; Hypercoagulopathy
MeSH headings : Animals; Area Under Curve; Female; Fibrinogen / analysis; Fibrinolytic Agents / administration & dosage; Fibrinolytic Agents / pharmacokinetics; Fibrinolytic Agents / therapeutic use; Half-Life; Horses / metabolism; Infusions, Intravenous / veterinary; Male; Partial Thromboplastin Time / veterinary; Prothrombin Time / veterinary; Thrombin Time / veterinary; Thrombosis / drug therapy; Thrombosis / veterinary; Tissue Plasminogen Activator / administration & dosage; Tissue Plasminogen Activator / pharmacokinetics; Tissue Plasminogen Activator / therapeutic use
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Sphingosine-1-phosphate exhibits anti-proliferative and anti-inflammatory effects in mouse models of psoriasis

JOURNAL OF DERMATOLOGICAL SCIENCE, 71(1), 29–36.

By: K. Schaper, J. Dickhaut, L. Japtok, M. Kietzmann, R. Mischke, B. Kleuser, W. Baeumer

author keywords: Imiquimod; Psoriasis; SCID mice; Sphingosine-1-phosphate
MeSH headings : Administration, Cutaneous; Aminoquinolines; Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / pharmacology; Betamethasone / analogs & derivatives; Betamethasone / pharmacology; Calcitriol / analogs & derivatives; Calcitriol / pharmacology; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Dermatologic Agents / administration & dosage; Dermatologic Agents / pharmacology; Disease Models, Animal; Female; Fingolimod Hydrochloride; Humans; Imiquimod; Keratinocytes / drug effects; Keratinocytes / metabolism; Keratinocytes / pathology; Local Lymph Node Assay; Lysophospholipids / administration & dosage; Lysophospholipids / pharmacology; Mice; Mice, Inbred BALB C; Mice, SCID; Propylene Glycols / administration & dosage; Propylene Glycols / pharmacology; Psoriasis / chemically induced; Psoriasis / drug therapy; Psoriasis / metabolism; Psoriasis / pathology; Receptors, Lysosphingolipid / drug effects; Receptors, Lysosphingolipid / metabolism; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Transplantation; Sphingosine / administration & dosage; Sphingosine / analogs & derivatives; Sphingosine / pharmacology; Sphingosine-1-Phosphate Receptors; Time Factors
Source: Web Of Science
Added: August 6, 2018

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