Center for Human Health and the Environment

Works Published in 2008

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Displaying works 201 - 213 of 213 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2008 journal article

TAK1 is a central mediator of NOD2 signaling in epidermal cells

JOURNAL OF BIOLOGICAL CHEMISTRY, 283(1), 137–144.

MeSH headings : Acetylmuramyl-Alanyl-Isoglutamine / pharmacology; Animals; Cell Line; Cell Line, Tumor; Cells, Cultured; Chemokines, CXC / genetics; Chemokines, CXC / metabolism; Electrophoretic Mobility Shift Assay; Humans; Immunity, Innate / drug effects; Immunoblotting; Immunoprecipitation; JNK Mitogen-Activated Protein Kinases / genetics; JNK Mitogen-Activated Protein Kinases / metabolism; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; MAP Kinase Kinase Kinases / genetics; MAP Kinase Kinase Kinases / metabolism; Mice; Mice, Mutant Strains; Models, Biological; NF-kappa B / genetics; NF-kappa B / metabolism; Nod2 Signaling Adaptor Protein / genetics; Nod2 Signaling Adaptor Protein / metabolism; Receptor-Interacting Protein Serine-Threonine Kinase 2 / genetics; Receptor-Interacting Protein Serine-Threonine Kinase 2 / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / drug effects; Transfection; Tumor Necrosis Factor-alpha / genetics; Tumor Necrosis Factor-alpha / metabolism; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR: It is shown that transforming growth factor β-activated kinase 1 (TAK1) is an essential intermediate of NOD2 signaling and its ablation may impair the skin barrier function leading to inflammation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Sex Differences in Serotonergic But Not γ-Aminobutyric Acidergic (GABA) Projections to the Rat Ventromedial Nucleus of the Hypothalamus

Endocrinology, 149(1), 397–408.

By: H. Patisaul n, A. Fortino* & E. Polston*

MeSH headings : Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus / metabolism; Dorsomedial Hypothalamic Nucleus / metabolism; Estradiol / pharmacology; Female; Genistein / pharmacology; Glutamate Decarboxylase / metabolism; Male; Neurons, Afferent / drug effects; Neurons, Afferent / metabolism; Neurons, Afferent / physiology; Posture / physiology; Rats; Rats, Sprague-Dawley; Serotonin / metabolism; Sex Characteristics; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / drug effects; Ventromedial Hypothalamic Nucleus / metabolism; Ventromedial Hypothalamic Nucleus / physiology; gamma-Aminobutyric Acid / metabolism
TL;DR: The findings suggest that the development of serotonergic inputs to the male VMNvl is orchestrated by neonatal estradiol exposure, and the hormone-dependent organization of these 5-HT projection patterns may be an important developmental mechanism accounting for sex-specific behaviors in adulthood. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

New contact sex pheromone components of the german cockroach, Blattella germanica, predicted from the proposed biosynthetic pathway

JOURNAL OF CHEMICAL ECOLOGY, 34(2), 229–237.

By: D. Eliyahu n, S. Nojima n, K. Mori & C. Schal n

Contributors: D. Eliyahu n, S. Nojima n, K. Mori & C. Schal n

author keywords: 27-Oxo-3; 11-dimethylheptacosan-2-one; 27-Hydroxy-3; 11-dimethylheptacosan-2-one; sex pheromone; Blattella germanica; german cockroach; methyl ketone; alcohol; aldehyde
MeSH headings : Alcohols / analysis; Alcohols / metabolism; Alcohols / pharmacology; Aldehydes / analysis; Aldehydes / metabolism; Aldehydes / pharmacology; Animals; Blattellidae / physiology; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Ketones / analysis; Ketones / metabolism; Ketones / pharmacology; Male; Sex Attractants / analysis; Sex Attractants / metabolism; Sex Attractants / pharmacology; Sexual Behavior, Animal / drug effects
TL;DR: It is shown that the epicuticle of the German cockroach does indeed contain these two compounds, 3,11-dimethylheptacosan-2-one and 27-oxo-3, 11-dimethyltestosterone-1-one, and that the contact sex pheromone of the female Germany cockroach, thus may consist of at least six biosynthetically related components. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

Identification and characterization of cuticular hydrocarbons from a rapid species radiation of hawaiian swordtailed crickets (Gryllidae : Trigonidiinae : Laupala)

JOURNAL OF CHEMICAL ECOLOGY, 34(2), 198–204.

By: S. Mullen*, J. Millar*, C. Schal n & K. Shaw*

Contributors: S. Mullen*, J. Millar*, C. Schal n & K. Shaw*

author keywords: chemical communication; speciation; mate recognition; pheromones; Laupala
MeSH headings : Animals; Biological Evolution; Female; Gas Chromatography-Mass Spectrometry; Gryllidae / metabolism; Hawaii; Hydrocarbons / analysis; Lipids / chemistry; Male
TL;DR: Big Island Laupala possessed a reduced number of alkenes as well as a reduction in the diversity of methyl-branch positions relative to species sampled from Maui (ancestral), thus supporting the hypothesis of a founder-induced loss of chemical diversity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 46(2), 139–146.

By: J. Gookin n, D. Foster n, M. Coccaro n & S. Stauffer n

author keywords: barrier function; enteral nutrition; epithelial defense; nitric oxide
MeSH headings : Alanine / administration & dosage; Analysis of Variance; Animals; Animals, Newborn; Arginine / administration & dosage; Atrophy; Chlorides / metabolism; Cryptosporidiosis / parasitology; Cryptosporidiosis / physiopathology; Cryptosporidiosis / therapy; Cryptosporidium parvum / growth & development; Cyclooxygenase Inhibitors / pharmacology; Diarrhea / parasitology; Diarrhea / physiopathology; Diarrhea / therapy; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Ileum / parasitology; Ileum / pathology; Ileum / physiology; Indomethacin / pharmacology; Intestinal Mucosa / parasitology; Intestinal Mucosa / pathology; Nitric Oxide / biosynthesis; Oocysts / growth & development; Parasite Egg Count; Prostaglandins / biosynthesis; Random Allocation; Severity of Illness Index; Swine
TL;DR: These studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C parvum–infected neonatal ileum. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Factors influencing landscape pattern of the seagrass Halophila decipiens in an oceanic setting

ESTUARINE COASTAL AND SHELF SCIENCE, 76(1), 163–174.

By: M. Fonseca*, W. Kenworth*, E. Griffith n, M. Hall*, M. Finkbeiner* & S. Bell*

author keywords: seagrass; scale; Halophila; disturbance; landscape; clonal; USA; Florida; eastern Gulf of Mexico; West Florida Shelf
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2008 personal communication

Human Proteinpedia enables sharing of human protein data

By: S. Mathivanan, M. Ahmed, N. Ahn, H. Alexandre, R. Amanchy, P. Andrews, J. Bader, B. Balgley ...

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Evolutionarily conserved cytogenetic changes in hematological malignancies of dogs and humans - man and his best friend share more than companionship

CHROMOSOME RESEARCH, 16(1), 145–154.

author keywords: chromosome; comparative; dog; evolution; leukemia; lymphoma
MeSH headings : Animals; Chromosome Aberrations; Conserved Sequence; Cytogenetics; Dogs; Evolution, Molecular; Hematologic Neoplasms / genetics; Humans; Male; Synteny / genetics; Translocation, Genetic
TL;DR: It is suggested that humans and dogs share an ancestrally retained pathogenetic basis for cancer and that cytogenetic evaluation of canine tumors may provide greater insight into the biology of tumorigenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 review

A review of chemical warfare agent simulants for the study of environmental behavior

[Review of ]. CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 38(2), 112–136.

By: S. Bartelt-Hunt*, D. Knappe n & M. Barlaz n

Contributors: S. Bartelt-Hunt*, D. Knappe n & M. Barlaz n

author keywords: microbial degradation; partition coefficient; simulant; toxicity; warfare agent
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

A new family of multiferrocene complexes with enhanced control of structure and stoichiometry via coordination-driven self-assembly and their electrochemistry

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(3), 839-+.

MeSH headings : Electrochemistry; Ferrous Compounds / chemistry; Metallocenes; Molecular Structure; Organometallic Compounds / chemical synthesis; Organometallic Compounds / chemistry
TL;DR: The design and synthesis of a new family of multiferrocene complexes with enhanced control of structure and stoichimetry via coordination-driven self-assembly is described, providing an enhanced understanding of the influence of structural factors on the electrochemistry of multifunctional electroactive supramolecular architectures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Synthesis, characterization, and application of lodoacetamide derivatives utilized for the ALiPHAT strategy

Journal of the American Chemical Society, 130(7), 2122-.

By: D. Williams, C. Meadows, I. Bori, A. Hawkridge, D. Comins & D. Muddiman

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2008 journal article

Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma

EUROPEAN RESPIRATORY JOURNAL, 31(1), 43–46.

By: M. Kraft, K. Adler*, J. Ingram, A. Crews*, T. Atkinson, C. Cairns, D. Krause, H. Chu

author keywords: asthma; epithelial cell; MUC5AC; Mycoplasma pneumoniae; toll-like receptor 2
MeSH headings : Adult; Asthma / immunology; Asthma / metabolism; Asthma / microbiology; Bronchoscopy / methods; Enzyme-Linked Immunosorbent Assay; Epithelial Cells / cytology; Epithelial Cells / microbiology; Female; Gene Expression Regulation; Humans; Male; Models, Biological; Mucin 5AC; Mucins / biosynthesis; Mucins / metabolism; Mycoplasma pneumoniae / metabolism; Mycoplasma pneumoniae / physiology; NF-kappa B / metabolism; Time Factors; Toll-Like Receptor 2 / metabolism
TL;DR: Mycoplasma pneumoniae exposure significantly increased MUC5AC mRNA and protein expression preferentially in airway epithelial cells isolated from asthmatic subjects, and the toll-like receptor 2 pathway may be involved in this process. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Cuticular hydrocarbons as maternal provisions in embryos and nymphs of the cockroach Blattella germanica

JOURNAL OF EXPERIMENTAL BIOLOGY, 211(4), 548–554.

By: Y. Fan n, D. Eliyahu n & C. Schal n

Contributors: Y. Fan n, D. Eliyahu n & C. Schal n

author keywords: cuticular hydrocarbons; maternal investment; waterproofing; communication; cockroach; Blattella germanica
MeSH headings : Animals; Cockroaches / embryology; Cockroaches / metabolism; Hydrocarbons / metabolism; Integumentary System / physiology; Nymph / metabolism
TL;DR: Results show, for the first time in any insect, that a mother provides a significant complement of her offspring's cuticular hydrocarbons. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
15. Life on Land (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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