Works Published in 2011

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Displaying works 1 - 20 of 38 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

Design and evaluation of buccoadhesive bi-layer tablet of atenolol

International Journal of Research in Pharmaceutical Sciences, 2(2), 100–103. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955369086&partnerID=MN8TOARS

By: K. Panneer, S. Ramkanth, R. Thirumurugan, K. Kumar & S. Raji

Contributors: K. Panneer, S. Ramkanth, R. Thirumurugan, K. Kumar & S. Raji

Source: ORCID
Added: July 16, 2022

2011 conference paper

Effects of pistachios on emerging CVD risk factors in moderately hypercholesterolemic individuals

The FASEB Journal, 25(S1), 971.21.

By: S. Holligan, S. Gebauer*, S. West*, C. Kay* & P. Kris-Etherton

Event: Federation of American Societies for Experimental Biology 2011 Meeting at Washington, DC

Sources: NC State University Libraries, ORCID
Added: March 19, 2021

2011 journal article

Preventive effects of protopanaxadiol and protopanaxatriol ginsenosides on liver inflammation and apoptosis in hyperlipidemic apoE KO mice

Genes & Nutrition, 7(2), 319–329.

By: S. Jang*, Y. Lim*, G. Valacchi*, S. Sorn*, H. Park*, N. Park*, M. Lee*

author keywords: Ginsenosides; Apoptosis; Apo E KO mice; LPO; NF kappa B; MAPK; Caspase; Cleaved PARP; Bcl-2; Hyperlipidemia
TL;DR: Different combinational treatment of PD and PT extracts might ameliorate the liver inflammation and apoptosis in hyperlipidemic apo E KO mice, which is atherosclerotic animal model. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021

2011 journal article

Increased levels of 4HNE-protein plasma adducts in Rett syndrome

Clinical Biochemistry, 44(5-6), 368–371.

author keywords: Rett syndrome; MeCP2; CDKL5; FOXG1; Oxidative stress; 4-Hydroxynonenal
MeSH headings : Adolescent; Adult; Aldehydes / blood; Blotting, Western; Child; Child, Preschool; Disease Progression; Forkhead Transcription Factors / genetics; Humans; Mutation; Nerve Tissue Proteins / genetics; Rett Syndrome / blood; Rett Syndrome / pathology; Young Adult
TL;DR: Under the OS point of view FOXG1-related RTT appears to be distinct from the MeCP2/CDKL5, suggesting a distinct mechanism involved in its pathogenesis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 11, 2020

2011 journal article

F4-neuroprostanes mediate neurological severity in Rett syndrome

Clinica Chimica Acta, 412(15-16), 1399–1406.

By: C. Signorini*, C. De Felice*, S. Leoncini*, A. Giardini*, M. D'Esposito*, S. Filosa*, F. Della Ragione*, M. Rossi* ...

author keywords: Rett syndrome; MeCP2; CDKL5; Neuroprostanes; Autism spectrum disorders; omega-3 polyunsaturated fatty acids
MeSH headings : Adult; Biomarkers / blood; Case-Control Studies; Child; Child, Preschool; Cohort Studies; Disease Progression; Female; Humans; Isoprostanes / blood; Methyl-CpG-Binding Protein 2 / genetics; Mutation; Neurologic Examination; Rett Syndrome / blood; Rett Syndrome / diagnosis; Young Adult
TL;DR: Quantification of plasma F₄-NeuroPs provides a novel RTT marker, related to neurological symptoms severity, mutation type and clinical presentation, and response to ω-3 PUFAs supplementation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 11, 2020

2011 journal article

Cigarette smoke exposure causes changes in Scavenger Receptor B1 level and distribution in lung cells

The International Journal of Biochemistry & Cell Biology, 43(7), 1065–1070.

By: G. Valacchi*, P. Davis*, E. Khan*, R. Lanir*, E. Maioli, A. Pecorelli*, C. Cross*, T. Goldkorn*

author keywords: Cigarette smoke; Scavenger Receptor B1; Lung; Vitamin E; Ubiquitination
MeSH headings : Animals; Biological Transport / drug effects; Cell Line, Tumor; Cell Membrane / metabolism; Humans; Immunohistochemistry; Lung / cytology; Lung Neoplasms / etiology; Mice; Microscopy, Confocal; RNA, Messenger / genetics; RNA, Messenger / metabolism; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / metabolism; Smoking / adverse effects; Time Factors; Tocopherols / metabolism; Ubiquitination / drug effects
TL;DR: Exposure to cigarette smoke induced changes in both sub-cellular redistribution and ubiquitination of Scavenger Receptor B1 together with in vivo data provides evidence that cigarette smoke exposure may alter lung's ability to control its tocopherol levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 11, 2020

2011 journal article

The metabolism and analysis of isoflavones and other dietary polyphenols in foods and biological systems

Food & Function, 2(5), 235.

By: S. Barnes*, J. Prasain*, T. D'Alessandro*, A. Arabshahi*, N. Botting*, M. Lila n, G. Jackson*, E. Janle*, C. Weaver*

MeSH headings : Animals; Biological Availability; Food; Genistein / analysis; Genistein / metabolism; Glucuronides / analysis; Glucuronides / metabolism; Glycosides / analysis; Glycosides / metabolism; Humans; Intestinal Mucosa / metabolism; Isoflavones / analysis; Isoflavones / metabolism; Liver / metabolism; Mass Spectrometry; Polyphenols / analysis; Polyphenols / metabolism
TL;DR: Critical questions about the absorption and tissue uptake of complex polyphenols such as the proanthocyanins can be answered by labeling thesepolyphenols with (14)C-sucrose in plant cell culture and then purifying them for use in animal experiments, routinely carried out with great sensitivity, specificity and quantification by LC-tandem mass spectrometry. (via Semantic Scholar)
Source: Crossref
Added: September 9, 2020

2011 journal article

Deliquescence Behavior and Chemical Stability of Vitamin C Forms (Ascorbic Acid, Sodium Ascorbate, and Calcium Ascorbate) and Blends

International Journal of Food Properties, 14(6), 1330–1348.

author keywords: Vitamin C; Deliquescence; Solubility; Stability
Source: Crossref
Added: August 28, 2020

2011 journal article

Beverage vs. Solid Fruits and Vegetables: Effects on Energy Intake and Body Weight

Obesity, 20(9), 1844–1850.

MeSH headings : Adolescent; Adult; Analysis of Variance; Beverages; Eating; Energy Intake; Energy Metabolism; Female; Fruit; Humans; Indiana / epidemiology; Male; Nutritive Value; Obesity / epidemiology; Obesity / metabolism; Surveys and Questionnaires; Thinness / epidemiology; Thinness / metabolism; Vegetables; Weight Gain; Young Adult
TL;DR: Energy consumed as beverages may be especially problematic for weight gain and advice to increase fruit and vegetable consumption should emphasize total energy intake because the additional energy contributed may promote weight gain, especially among overweight and obese individuals. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

Survey of Polyphenol Constituents in Grapes and Grape-Derived Products

Journal of Agricultural and Food Chemistry, 59(19), 10586–10593.

By: Y. Xu*, J. Simon*, C. Welch, J. Wightman*, M. Ferruzzi*, L. Ho*, G. Passinetti, Q. Wu*

author keywords: grape; LC-MS; polyphenols; anthocyanins; flavonoids; proanthocyanidin; phenolic acid
MeSH headings : Anthocyanins / analysis; Beverages / analysis; Chromatography, High Pressure Liquid; Flavonoids / analysis; Fruit / chemistry; Hydroxybenzoates / analysis; Mass Spectrometry; Polyphenols / analysis; Seeds / chemistry; Vitis / chemistry; Wine / analysis
TL;DR: A rapid and comprehensive qualitative method has been developed to characterize the different classes of polyphenols, such as anthocyanins, flavonols, phenolic acids, and flavanols/proanthocyanidins in grape products. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

Modification of Curcumin with Polyethylene Glycol Enhances the Delivery of Curcumin in Preadipocytes and Its Antiadipogenic Property

Journal of Agricultural and Food Chemistry, 59(3), 1012–1019.

author keywords: Curcumin; polyethylene glycol; solubility; bioavailability; 3T3-L1; adipogenesis
MeSH headings : 3T3-L1 Cells; Adipocytes / metabolism; Adipogenesis / drug effects; Animals; Curcumin / chemistry; Curcumin / metabolism; Curcumin / pharmacology; Mice; Polyethylene Glycols / chemistry; Polyethylene Glycols / metabolism; Solubility; Water
TL;DR: Pgylation-improved water solubility and cellular retention ofCCM may be uniquely useful for improving the delivery of CCM in preadipocytes and its antiadipogenic ability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Crossref
Added: August 28, 2020

2011 journal article

Carotenoid bioaccessibility from whole grain and decorticated yellow endosperm sorghum porridge

Journal of Cereal Science, 54(3), 450–459.

author keywords: Sorghum; Carotenoids; In vitro digestion; Bioaccessibility
TL;DR: The effects of agronomic manipulation on sorghum carotenoid contents at selected stages of kernel development and maturation are explored and bioaccessibility from matured yellow-endosperm Sorghum varieties (P88 and P1222) is assessed, by comparing porridge made from sorghums whole and decorticated milled grains. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

Neuroprotective and metabolic effects of resveratrol: Therapeutic implications for Huntington's disease and other neurodegenerative disorders

Experimental Neurology, 232(1), 1–6.

MeSH headings : Animals; Disease Models, Animal; Huntington Disease / drug therapy; Huntington Disease / metabolism; Stilbenes / pharmacology; Stilbenes / therapeutic use
TL;DR: A recent study examined the therapeutic potential of a micronised proprietary resveratrol formulation, SRT501 in the N171-82Q transgenic mouse model of Huntington's disease, finding that SRT 501 treatment did not lead to significant improvement in weight loss, motor performance, survival and striatal atrophy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Crossref
Added: August 28, 2020

2011 journal article

Mango modulates body fat and plasma glucose and lipids in mice fed a high-fat diet

British Journal of Nutrition, 106(10), 1495–1505.

By: E. Lucas*, W. Li*, S. Peterson*, A. Brown*, S. Kuvibidila*, P. Perkins-Veazie n, S. Clarke*, B. Smith*

author keywords: Mango; Glucose; Diabetes; Cholesterol; High-fat diet
MeSH headings : Adiponectin / blood; Adiposity; Animals; Blood Glucose / metabolism; Body Composition; Body Weight; Dietary Fats / administration & dosage; Gene Expression Profiling; Glucose Tolerance Test; Insulin / blood; Insulin Resistance; Leptin / blood; Lipids / blood; Male; Mangifera; Mice; Mice, Inbred C57BL; Organ Size; Real-Time Polymerase Chain Reaction
TL;DR: It is demonstrated that incorporation of freeze-dried mango in the diet of mice improved glucose tolerance and lipid profile and reduced adiposity associated with a high-fat (HF) diet. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2011 journal article

A gram scale synthesis of a multi-13C-labelled anthocyanin, [6,8,10,3′,5′-13C5]cyanidin-3-glucoside, for use in oral tracer studies in humans

Chemical Communications, 47(38), 10596.

By: Q. Zhang*, N. Botting* & C. Kay*

MeSH headings : Administration, Oral; Anthocyanins / chemical synthesis; Anthocyanins / chemistry; Anthocyanins / pharmacokinetics; Carbon Isotopes / chemistry; Glucosides / chemical synthesis; Glucosides / chemistry; Glucosides / pharmacokinetics; Humans; Isotope Labeling; Stereoisomerism
TL;DR: The major dietary anthocyanin, cyanidin-3-glucoside, was prepared from three units of diethyl [2-( 13)C]malonate and one unit of [1,3-(13)C(2)]acetone, such that five isotope locations were distributed throughout the molecule to provide a penta-C(5)-labelled anthocianin for human stable-isotope tracer studies. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: March 8, 2020

2011 chapter

Phytochemicals

In Nutrition and Metabolism (pp. 339–352).

Sources: Crossref, ORCID
Added: January 5, 2020

2011 journal article

Anthocyanins Remain Stable during Commercial Blackcurrant Juice Processing

Journal of Food Science, 76(6), S408–S414.

By: G. Woodward*, D. McCarthy*, D. Pham-Thanh* & C. Kay*

author keywords: anthocyanin; flavonoids; food processing; juice
MeSH headings : Anthocyanins / analysis; Anthocyanins / chemistry; Antioxidants / chemistry; Beverages / analysis; Chromatography, High Pressure Liquid; Filtration; Food Additives / chemistry; Food Additives / metabolism; Food Handling; Fruit / chemistry; Gallic Acid / analysis; Hot Temperature; Hydrolysis; Hydroxybenzoates / analysis; Models, Chemical; Pasteurization; Pectins / analysis; Pectins / metabolism; Phenols / analysis; Polygalacturonase / metabolism; Ribes / chemistry; Sulfites / chemistry; United Kingdom
TL;DR: Assessment of the recovery and formation of anthocyanins and their free phenolic acid degradation products during the commercial processing of blackcurrant juice concentrate provides crucial data directly applicable to commercial juice processing, such as improving Anthocyanin yield and practical considerations for anthocianin stability and degradation. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 5, 2020

2011 journal article

A potential mechanism of action of dietary anthocyanins: modulation of endothelial superoxide production by phenolic acid metabolites

Proceedings of the Nutrition Society, 70(OCE4).

By: G. Woodward*, A. Cassidy* & C. Kay*

TL;DR: Evidence is presented that anthocyanins and their metabolites attenuate Ang II-induced endothelial superoxide production and that the cellular activity of anthocianins was enhanced following degradation and metabolism to phenolic acid metabolites. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020

2011 journal article

Reply to C Drossard et al

The American Journal of Clinical Nutrition, 93(4), 866–867.

Sources: Web Of Science, NC State University Libraries
Added: January 5, 2020

2011 journal article

Effects of sugar-sweetened and sugar-free cocoa on endothelial function in overweight adults

International Journal of Cardiology, 149(1), 83–88.

author keywords: Cocoa; Endothelial function; Cardiac risk
MeSH headings : Adult; Biomarkers / metabolism; Brachial Artery / drug effects; Brachial Artery / physiology; Cacao; Cardiovascular Diseases / diet therapy; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / prevention & control; Cholesterol / blood; Cross-Over Studies; Dietary Sucrose / administration & dosage; Endothelium, Vascular / drug effects; Endothelium, Vascular / physiology; Female; Humans; Male; Middle Aged; Overweight / diet therapy; Overweight / epidemiology; Placebos; Risk Factors; Vasodilation / drug effects; Vasodilation / physiology
TL;DR: Daily cocoa ingestion improves EF independently of other biomarkers of cardiac risk, and does not cause weight gain, and sugar-free preparations may further augment endothelial function. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 13, 2019

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