Works Published in 2015
Displaying works 1 - 20 of 69 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 conference paper
Next generation transcriptome sequencing to elucidate molecular mechanism of Self-incompatibility in tea
Plant Physiology Congress. Poster presented at the Plant Physiology Congress, JNU, New Delhi.
Event: Plant Physiology Congress at JNU, New Delhi on December 11-14, 2015
Source: NC State University Libraries
Added: August 24, 2023
2015 conference paper
NGS Based Transcriptome Sequencing of Multiple Diverse Genotypes: An Efficient Approach to Develop Functionally Relevant Marker Resource in Tea
International Plant Physiology Congress. Presented at the International Plant Physiology Congress, JNU, New Delhi.
Event: International Plant Physiology Congress at JNU, New Delhi on December 11-14, 2015
Source: NC State University Libraries
Added: August 24, 2023
2015 conference paper
Exploiting Next generation sequencing for creation of genomic resources in Tea
5th International Conference on Next Generation Genomics & Integrated Breeding for Crop improvement. Presented at the 5th International Conference on Next Generation Genomics & Integrated Breeding for Crop improvement, ICRISAT, Patancheru, India.
Event: 5th International Conference on Next Generation Genomics & Integrated Breeding for Crop improvement at ICRISAT, Patancheru, India on February 18-20, 2015
Source: NC State University Libraries
Added: August 24, 2023
2015 journal article
Corrigendum to “Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders” [Biochem. Biophys. Res. Commun. 417 (1) (6 January 2012) 457–461]
Biochemical and Biophysical Research Communications, 460(2), 489.
Source: Crossref
Added: August 16, 2021
2015 conference paper
Sulfurophane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo
International Journal of Experimental Pathology, 96(2), A24.
Event: Joint meeting of British Societies for Matrix Biology and Developmental Biology at University of East Anglia (Norwich) on September 1-3, 2014
Source: NC State University Libraries
Added: March 12, 2021
2015 journal article
Carbohydrate and Phytochemical Digestibility in Pasta
Food Engineering Reviews, 8(1), 76–89.
author keywords: Pasta products; Raw materials; Processing technologies; Carbohydrates digestibility; Phytochemicals; Glycemic index
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: January 21, 2021
2015 journal article
The bioactivity of flavonoids is likely the result of cumulative low exposure to a variety of structurally similar phenolic metabolites
The FASEB Journal, 29(Supplement 1), 118.4.
TL;DR:
The evidence suggests that bioactivity of flavonoids in vivo results from low exposure to a variety of structurally similar metabolites modifying inflammation and cellular adhesion pathways.
(via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: November 6, 2020
2015 journal article
The Air Quality Health Index and Emergency Department Visits for Urticaria in Windsor, Canada
Journal of Toxicology and Environmental Health, Part A, 78(8), 524–533.
MeSH headings : Adolescent; Adult; Age Factors; Aged; Air Pollutants / analysis; Air Pollutants / toxicity; Air Pollution / adverse effects; Child; Emergency Service, Hospital; Environmental Exposure / adverse effects; Environmental Illness / chemically induced; Environmental Illness / epidemiology; Environmental Illness / therapy; Environmental Monitoring; Female; Hospitals, Urban; Humans; Infant; Male; Models, Biological; Nitrogen Dioxide / analysis; Nitrogen Dioxide / toxicity; Ontario / epidemiology; Oxidants, Photochemical / analysis; Oxidants, Photochemical / toxicity; Ozone / analysis; Ozone / toxicity; Particulate Matter / analysis; Particulate Matter / toxicity; Risk; Sex Characteristics; Urban Health; Urticaria / chemically induced; Urticaria / epidemiology; Urticaria / therapy
TL;DR:
Findings demonstrated associations between ambient air pollution and urticarial confirming that air pollution affects skin conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Correction: Wound healing properties of hyaluronan derivatives bearing ferulate residues
Journal of Materials Chemistry B, 3(36), 7307–7307.
TL;DR:
Correction for 'Wound healing properties of hyaluronan derivatives bearing ferulate residues' by Giuseppe Valacchi et al., J. Mater Chem.
(via Semantic Scholar)
pubs.rsc.org (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Wound healing properties of hyaluronan derivatives bearing ferulate residues
Journal of Materials Chemistry B, 3(35), 7037–7045.
TL;DR:
The data presented herein suggest HAFA-17 as a possible future drug for the therapeutic treatment of acute and chronic wounds as well as in vitro and in vivo in preclinical models.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Protective Effect of Palmitoylethanolamide in a Rat Model of Cystitis
Journal of Urology, 193(4), 1401–1408.
author keywords: urinary bladder; cystitis; interstitial; palmidrol; cyclophosphamide; receptors; cannabinoid
MeSH headings : Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Cyclophosphamide; Cystitis / chemically induced; Cystitis / prevention & control; Disease Models, Animal; Ethanolamines / therapeutic use; Female; Palmitic Acids / therapeutic use; Rats; Rats, Wistar
TL;DR:
There is strong evidence for a protective role of PEA as well as an alteration in bladder levels of P EA and of some of its targets in cyclophosphamide induced cystitis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
The effects of three different classes of anti-inflammatory agents on in vitro human osteoarthritic chondrocytes exposed to IL-1β
Osteoarthritis and Cartilage, 23, A159–A160.
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β
International Immunopharmacology, 28(1), 794–801.
author keywords: Chondrocyte; Osteoarthritis; Nitric oxide-selective cyclooxigenase-2 inhibitors; Cyclooxigenase inhibitor nitric oxide donors; Naproxen; VA694
MeSH headings : Aged; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cell Culture Techniques; Cell Survival / drug effects; Cells, Cultured; Chondrocytes / drug effects; Chondrocytes / immunology; Cyclooxygenase 2 / genetics; Dinoprostone / analysis; Dinoprostone / metabolism; Dose-Response Relationship, Drug; Gene Expression / drug effects; Humans; Interleukin-1beta / pharmacology; Matrix Metalloproteinases / genetics; Middle Aged; Molecular Structure; NF-kappa B / immunology; Naproxen / analogs & derivatives; Naproxen / chemistry; Naproxen / pharmacology; Nitrates / chemistry; Nitrates / pharmacology; Osteoarthritis, Hip / immunology; Pyrroles / chemistry; Pyrroles / pharmacology
TL;DR:
VA694, Naproxcinod and Naproxen, at both concentrations analyzed, significantly counteracted the negative effects induced by IL-1β, and suggest that these drugs exert anti-inflammatory and chondroprotective effects on OA chondROcytes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin
Cancer Letters, 360(1), 17–27.
author keywords: Rottlerin; AMPK; mTOR; Raptor; Autophagy
MeSH headings : AMP-Activated Protein Kinases / metabolism; Acetophenones / pharmacology; Adenocarcinoma / enzymology; Adenocarcinoma / genetics; Adenocarcinoma / pathology; Antineoplastic Agents / pharmacology; Autophagy / drug effects; Benzopyrans / pharmacology; Breast Neoplasms / enzymology; Breast Neoplasms / genetics; Breast Neoplasms / pathology; Female; Humans; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes / antagonists & inhibitors; Multiprotein Complexes / metabolism; Phosphorylation; Protein Kinase C-delta / metabolism; Protein Kinase Inhibitors / pharmacology; RNA Interference; Signal Transduction / drug effects; TOR Serine-Threonine Kinases / antagonists & inhibitors; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Time Factors; Transfection
TL;DR:
It is demonstrated that the Rottlerin-triggered autophagy is mediated by inhibition of mTORC1 activity through a novel AMPK and m TORC1 phosphorylation-independent mechanism, likely mediated by the direct interaction between Rottlersin and mTOR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage
Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(10), 2066–2074.
author keywords: Oxidative stress; NADPH oxidase; Glutathione peroxidase; Superoxide dismutase thioredoxin-reductases; 4HNE
TL;DR:
The findings suggest that the systemic OS levels in RTT can be a consequence of both: increased endogenous oxidants as well as altered mitochondrial biogenesis with a decreased activity of defensive enzymes that leads to posttranslational oxidant protein modification and a proteasome activity impairment.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy
Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(3), 507–519.
author keywords: 4-Hydroxy-2-nonenal; Matrix metalloproteinase; NADPH oxidase; Aquaporin-4; Drug-resistant epilepsy
MeSH headings : Adolescent; Adult; Aldehydes / metabolism; Aquaporin 4 / metabolism; Astrocytes / metabolism; Astrocytes / pathology; Child, Preschool; Drug Resistance; Enzyme Activation; Epilepsy / mortality; Epilepsy / pathology; Female; Hippocampus / metabolism; Hippocampus / pathology; Humans; Lipid Peroxidation; Male; Membrane Glycoproteins / metabolism; NADPH Oxidase 2; NADPH Oxidases / metabolism; Neurodegenerative Diseases / metabolism; Neurodegenerative Diseases / pathology; Neurons / metabolism; Neurons / pathology; Superoxides / metabolism; Water-Electrolyte Balance
TL;DR:
It is suggested that seizure induces oxidative damage as well as neuronal loss, thereby promoting neuronal hyperexcitability, also affecting water and ion balance by AQP4 modulation, and thus generating a vicious cycle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
New functionally-enhanced soy proteins as food ingredients with anti-viral activity
VirusDisease, 26(3), 123–132.
TL;DR:
Anti-viral properties of both cranberry juice-en enriched and cranberry pomace polyphenol-enriched soy protein isolate (CB-SPI and CBP- SPI) were tested against influenza viruses in vitro and in ovo and suggest CB-SPi and CBPs may have preventative and therapeutic potential against viral infections that cause diseases of the respiratory and gastro-intestinal tract.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 4, 2020
2015 journal article
Novel application of brain-targeting polyphenol compounds in sleep deprivation-induced cognitive dysfunction
Neurochemistry International, 89, 191–197.
author keywords: Sleep deprivation; Polyphenols; Cognitive dysfunction; Resilience; Memory consolidation
TL;DR:
It is found that BDPP significantly improves sleep deprivation-induced contextual memory deficits, possibly through the activation of CREB and mTOR signaling pathways, and the feasibility of using select brain-targeting polyphenol compounds derived from BDPp as potential therapeutic agents in promoting resilience against sleep deprivation -induced cognitive dysfunction is suggested.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2015 journal article
Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization
Molecular Nutrition & Food Research, 59(6), 1025–1040.
author keywords: -Amyloid; Bioavailability; Grape seed polyphenol extract; Phenolic metabolites; Proanthocyanidins
MeSH headings : Alzheimer Disease / drug therapy; Amyloid beta-Peptides / antagonists & inhibitors; Amyloid beta-Peptides / metabolism; Animals; Anthocyanins / administration & dosage; Anthocyanins / blood; Anthocyanins / pharmacokinetics; Biological Availability; Brain / metabolism; Fermentation; Gastrointestinal Microbiome; Grape Seed Extract / administration & dosage; Grape Seed Extract / blood; Grape Seed Extract / pharmacokinetics; Hydroxybenzoates / blood; Hydroxybenzoates / metabolism; Intestines / drug effects; Intestines / microbiology; Male; Peptide Fragments / antagonists & inhibitors; Peptide Fragments / metabolism; Phenols / metabolism; Polyphenols / administration & dosage; Polyphenols / blood; Polyphenols / pharmacokinetics; Propionates / metabolism; Rats; Rats, Sprague-Dawley
TL;DR:
Important contribution of the intestinal microbiota to the protective activities of GSPE (as well as other polyphenol preparations) in AD is suggested.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2015 journal article
Physicochemical, bioactive and functional evaluation of the exotic fruits Opuntia ficus-indica AND Pilosocereus pachycladus Ritter from the Brazilian caatinga
Journal of Food Science and Technology.
author keywords: Caatinga; Cactaceae fruits; Phenolics; Betalains
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: March 6, 2020
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