Works Published in 2009
Displaying works 1 - 20 of 24 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 journal article
Soy protein isoflavones, serum lipids and markers of oxidation and inflammation
Journal of Nutrition, 139, 1–7.
Source: NC State University Libraries
Added: March 26, 2021
2009 journal article
Herbicide Treatments Alter Carotenoid Profiles for14C Tracer Production from Tomato (Solanum lycopersicum cv. VFNT cherry) Cell Cultures
Journal of Agricultural and Food Chemistry, 57(11), 4614–4619.
author keywords: Solanum lycopersicum; bleaching herbicide; radiolabeling; metabolic tracer; cell culture; lycopene; phytoene; phytofluene
MeSH headings : Carbon Radioisotopes / metabolism; Carotenoids / metabolism; Cells, Cultured; Herbicides / pharmacology; Solanum lycopersicum / drug effects; Solanum lycopersicum / metabolism
TL;DR:
Improved culture conditions efficiently provided sufficient (14)C-carotenoids for future cell culture and animal metabolic tracking studies and led to a small increase in labeling efficiency.
(via Semantic Scholar)
europepmc.org (repository)
Sources: Crossref, NC State University Libraries
Added: January 24, 2021
2009 journal article
In vivo metabolic tracking of 14C-radiolabelled isoflavones in kudzu (Pueraria lobata) and red clover (Trifolium pratense) extracts
British Journal of Nutrition, 102(10), 1523–1530.
author keywords: Kudzu; Red clover; Radiolabelling; Pharmacokinetics
MeSH headings : Animals; Carbon / chemistry; Carbon Radioisotopes; Cells, Cultured; Extracellular Fluid / chemistry; Isoflavones / blood; Isoflavones / chemistry; Isoflavones / metabolism; Male; Plant Roots / cytology; Pueraria / chemistry; Rats; Rats, Sprague-Dawley; Time Factors; Trifolium / chemistry
TL;DR:
Serum pharmacokinetics suggest that extracts from kudzu may undergo enterohepatic circulation, and both extracts were rapidly absorbed, distributed in various tissues, and largely eliminated in the urine and faeces.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 24, 2021
2009 journal article
Influences of Harvest Date and Location on the Levels of β-Carotene, Ascorbic Acid, Total Phenols, the in Vitro Antioxidant Capacity, and Phenolic Profiles of Five Commercial Varieties of Mango (Mangifera indicaL.)
Journal of Agricultural and Food Chemistry, 57(22), 10825–10830.
author keywords: Mangiferin; ellagic acid; gallotannins; tropical fruit; polyphenol; vitamin C; Mangifera indica L.; antioxidant; HPLC-MS
MeSH headings : Antioxidants / analysis; Ascorbic Acid / analysis; Ellagic Acid / analysis; Fruit / chemistry; Fruit / growth & development; Hydrolyzable Tannins / analysis; Mangifera / chemistry; Mangifera / growth & development; Phenols / analysis; Species Specificity; Time Factors; Xanthones / analysis; beta Carotene / analysis
TL;DR:
Large fruit-to-fruit variations in the concentrations of these compounds occurred within sets of mangoes of the same cultivar with the same harvest location and date, and similar trends were observed in the DPPH radical scavenging activities among the five varieties.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Crossref
Added: November 14, 2020
2009 journal article
Nitroxide radical TEMPO reduces ozone-induced chemokine IL-8 production in lung epithelial cells
Toxicology in Vitro, 23(3), 365–370.
author keywords: Ozone; IL-8; TEMPO; Lung
MeSH headings : Cell Line, Tumor; Cell Survival / drug effects; Cyclic N-Oxides / pharmacology; Free Radical Scavengers / pharmacology; Free Radicals; Gene Expression / drug effects; Humans; Interleukin-8 / biosynthesis; Interleukin-8 / genetics; Lung Neoplasms / drug therapy; Lung Neoplasms / metabolism; Lung Neoplasms / pathology; Oxidants, Photochemical / toxicity; Ozone / toxicity; RNA, Messenger / metabolism; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism; Respiratory Mucosa / pathology
TL;DR:
Evidence that TEMPO reacts with O(3) and/or its cytotoxic products and may provide protections against O(2,2,6,6-tetramethylpiperidine-N-oxyl)-induced biotoxicities is provided.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 11, 2020
2009 journal article
Endothelin receptor A expression in human inflammatory cells
Regulatory Peptides, 158(1-3), 1–5.
author keywords: Endothelin; Neutrophils; Macrophages; Inflammation
MeSH headings : Base Sequence; Blotting, Western; Cell Line, Tumor; DNA Primers; Endothelin-1 / metabolism; Humans; Immunohistochemistry; Macrophages / metabolism; Neutrophils / metabolism; Receptor, Endothelin A / metabolism; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
Considering that the overproduction of ET-1 following endothelial dysfunction and inflammation, contributes to pathophysiological processes such as vascular hypertrophy, cell proliferation and fibrosis, the results suggest that PMNs and MØs can also play a key role in vascular dysfunctions via the possible formation of an autocrine loop betweenET-1 and ET(A).
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 11, 2020
2009 journal article
In vitro and in vivo evaluation of the prebiotic activity of water-soluble blueberry extracts
World Journal of Microbiology and Biotechnology, 25(7), 1243–1249.
author keywords: Blueberry extract; Prebiotic activity; Lactobacilli; Bifidobacteria
TL;DR:
The results demonstrated for the first time that addition of BBE from both cultivars to broth media containing pure cultures of Lactobacilli and Bifidobacteriumbreve resulted in a significant increase in the population size of these strains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020
2009 journal article
In vitro production of radiolabeled red clover (Trifolium pratense) isoflavones
Plant Cell, Tissue and Organ Culture (PCTOC), 98(2), 147–156.
author keywords: Red clover; Isoflavones; Metabolic tracers; Plant cell culture; Copper chloride; Radiolabeling; Trifolium pratense
TL;DR:
Varying levels and timing of copper chloride elicitor did not significantly affect isoflavone accumulation, and approximately 38% of the 14C-sucrose dose accumulated in the cells.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020
2009 journal article
Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases
Pharmaceutical Biology, 47(8), 768–773.
author keywords: Botanicals; isoflavones; catechins; bone resorption; cognitive function; cancer
TL;DR:
The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020
2009 journal article
Influence of Chocolate Matrix Composition on Cocoa Flavan-3-ol Bioaccessibility In Vitro and Bioavailability in Humans
Journal of Agricultural and Food Chemistry, 57(20), 9418–9426.
author keywords: Theobroma cacao; food matrix; chocolate; catechin; epicatechin; bioavailability; in vitro digestion; Caco-2 cells
MeSH headings : Beverages / analysis; Biological Availability; Cacao / chemistry; Caco-2 Cells; Candy / analysis; Cross-Over Studies; Female; Flavonoids / administration & dosage; Flavonoids / blood; Flavonoids / pharmacokinetics; Humans; Male; Milk Proteins / analysis; Plant Extracts / administration & dosage; Plant Extracts / blood; Plant Extracts / pharmacokinetics; Young Adult
TL;DR:
The data suggest that bioavailability of cocoa flavan-3-ols is likely similar from typical commercial cocoa based foods and beverages, but that the physical form and sucrose content may influence T(MAX) and C(MAX).
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2009 journal article
C1 Régulation des taux cérébraux de peptide Aß par l’AMP kinase
Revue Neurologique, 165(10), 19.
Source: Crossref
Added: August 28, 2020
2009 journal article
Impact of phytochemical-rich foods on bioaccessibility of mercury from fish
Food Chemistry, 112(1), 46–50.
author keywords: mercury; bioaccessibility; phytochemical; in vitro digestion
Source: Crossref
Added: August 28, 2020
2009 journal article
Acute Fish Oil and Soy Isoflavone Supplementation Increase Postprandial Serum (n-3) Polyunsaturated Fatty Acids and Isoflavones but Do Not Affect Triacylglycerols or Biomarkers of Oxidative Stress in Overweight and Obese Hypertriglyceridemic Men
The Journal of Nutrition, 139(6), 1128–1134.
MeSH headings : Biomarkers; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Fatty Acids, Omega-3 / blood; Fish Oils / administration & dosage; Fish Oils / pharmacology; Humans; Hypertriglyceridemia / blood; Isoflavones / blood; Isoflavones / pharmacology; Male; Middle Aged; Overweight / blood; Oxidative Stress / physiology; Postprandial Period; Soybeans; Triglycerides / blood
TL;DR:
The current study adds to a limited literature on the acute effects of FO and ISO interventions on postprandial biomarkers of CVD risk by determining the effects of acutely supplementing a high-fat, high-fructose meal with fish oil and is oflavone placebo (FO) and fish oil placebo and soy isoflavones (ISO).
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 5, 2020
2009 journal article
Anthocyanin Stability and Recovery: Implications for the Analysis of Clinical and Experimental Samples
Journal of Agricultural and Food Chemistry, 57(12), 5271–5278.
author keywords: Degradation; anthocyanin; phenolic acids; flavonoid; stability
MeSH headings : Anthocyanins / chemistry; Anthocyanins / metabolism; Humans; Models, Biological
TL;DR:
Data indicate that significant portions of ingested anthocyanins are likely to degrade to phenolic acids and aldehyde in vivo, and these compounds should be the target of future bioavailability and bioactivity studies to establish the true occurrence and impact of anthcyanins on human health.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 13, 2019
2009 journal article
The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products
Molecular Nutrition & Food Research, 53(S1), S92–S101.
author keywords: Anthocyanin; Degradation; Flavonoid; Metabolite; Phenolic
MeSH headings : Anthocyanins / administration & dosage; Anthocyanins / chemistry; Anthocyanins / metabolism; Biological Availability; Caco-2 Cells; Culture Media; Diet; Drug Stability; Glucosides / chemistry; Glucosides / metabolism; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics
TL;DR:
Data suggest a significant proportion of intestinal metabolites of anthocyanins are likely to be conjugates of their degradation products, including phenolic acid and aldehyde products of degradation, along with their respective metabolites.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 13, 2019
2009 journal article
Cardiovascular disease risk biomarkers and liver and kidney function are not altered in postmenopausal women after ingesting an elderberry extract rich in anthocyanins for 12 weeks
The Journal of Nutrition, 139(12), 2266–2271.
Source: ORCID
Added: November 13, 2019
2009 journal article
Hypoglycemic activity of a novel anthocyanin-rich formulation from lowbush blueberry, Vaccinium angustifolium Aiton
Phytomedicine, 16(5), 406–415.
Contributors: M. Grace* , D. Ribnicky*, P. Kuhn *, A. Poulev*, S. Logendra*, G. Yousef *, I. Raskin *, M. Lila*
author keywords: Blueberry; Vaccinium angustifolium; Anthocyanins; Malvidin; Diabetes; Hyperglycemia; Hypoglycemia; Labrasol
MeSH headings : Animals; Anthocyanins / analysis; Anthocyanins / pharmacology; Blood Glucose / drug effects; Blueberry Plants; Drug Delivery Systems; Drug Therapy, Combination; Glucosides / analysis; Glucosides / pharmacology; Glycerides; Hypoglycemic Agents / chemistry; Hypoglycemic Agents / pharmacology; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Organic Chemicals / administration & dosage; Organic Chemicals / pharmacology; Phenols / pharmacology; Plant Extracts / chemistry; Plant Extracts / pharmacology
TL;DR:
It is demonstrated that anthocyanins from blueberry have the potency to alleviate symptoms of hyperglycemia in diabetic C57b1/6J mice and their bio-enhancing effect, most likely due to increasing the bioavailability of the administered preparations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: November 12, 2019
2009 journal article
Phytochemical characterization of an adaptogenic preparation from Rhodiola heterodonta
Natural Product Communications, 4(8), 1053–1058. http://www.scopus.com/inward/record.url?eid=2-s2.0-73949106585&partnerID=MN8TOARS
Contributors: M. Grace , G. Yousef, A. Kurmukov, I. Raskin & M. Lila
Source: ORCID
Added: November 12, 2019
2009 journal article
Characteristic flavonoids from Acacia burkittii and A. acuminata heartwoods and their differential cytotoxicity to normal and leukemia cells
Natural Product Communications, 4(1), 69–76. http://www.scopus.com/inward/record.url?eid=2-s2.0-66849101227&partnerID=MN8TOARS
Contributors: M. Grace , G. Wilson, F. Kandil, E. Dimitriadis & R. Coates
Source: ORCID
Added: November 12, 2019
2009 journal article
Oral administration of triptolide ameliorates the clinical signs of experimental autoimmune encephalomyelitis (EAE) by induction of HSP70 and stabilization of NF-κB/IκBα transcriptional complex
Journal of Neuroimmunology, 217(1-2), 28–37.
author keywords: EAE; Hsp70; Inflammation; NF-kappa B; Oral; Triptolide
MeSH headings : Administration, Oral; Analysis of Variance; Animals; Cell Line, Transformed; Cytokines / metabolism; Cytoplasm / drug effects; Cytoplasm / metabolism; Disease Models, Animal; Diterpenes / administration & dosage; Diterpenes / pharmacology; Encephalomyelitis, Autoimmune, Experimental / chemically induced; Encephalomyelitis, Autoimmune, Experimental / metabolism; Encephalomyelitis, Autoimmune, Experimental / pathology; Encephalomyelitis, Autoimmune, Experimental / prevention & control; Epoxy Compounds / administration & dosage; Epoxy Compounds / pharmacology; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; I-kappa B Proteins / metabolism; Immunoprecipitation; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / pharmacology; Lymph Nodes / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice; Myelin Proteolipid Protein; NF-KappaB Inhibitor alpha; NF-kappa B / metabolism; Peptide Fragments; Phenanthrenes / administration & dosage; Phenanthrenes / pharmacology; Phosphorylation / drug effects; Phytotherapy / methods; RNA, Messenger / metabolism; Signal Transduction / drug effects; Time Factors; Tripterygium / chemistry; Up-Regulation / drug effects
TL;DR:
Triptolide delayed disease onset, reduced clinical symptoms, decreased the relapse rate, and suppressed inflammation and demyelination in CNS tissue of EAE mice when compared to vehicle-treated animals, indicating that daily oral administration of triptolide exhibits not only a preventive but also a therapeutic effect on EAE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: November 11, 2019
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