Works Published in 2016
Displaying works 21 - 40 of 117 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Erratum: Corrigendum: The spotted gar genome illuminates vertebrate evolution and facilitates human-teleost comparisons
Nature Genetics, 48(6), 700–700.
TL;DR:
The draft spotted gar genome sequence is made publicly available, the assembly LepOcu1 publicly available from NCBI since 13 January 2012 under accession code GCA000242695.
(via Semantic Scholar)
www.nature.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019
2016 journal article
Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish
The Journal of Experimental Medicine, 213(6), 979–992.
MeSH headings : Amino Acid Substitution; Animals; DNA-Binding Proteins / genetics; DNA-Binding Proteins / immunology; Hematopoiesis / genetics; Hematopoiesis / immunology; Hematopoietic Stem Cells / immunology; Hematopoietic Stem Cells / pathology; Killer Cells, Natural / immunology; Killer Cells, Natural / pathology; Mutation, Missense; Neoplastic Stem Cells / immunology; Neoplastic Stem Cells / pathology; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / immunology; Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology; T-Lymphocytes / immunology; T-Lymphocytes / pathology; Transcription, Genetic / genetics; Transcription, Genetic / immunology; Zebrafish / genetics; Zebrafish / immunology; Zebrafish Proteins / genetics; Zebrafish Proteins / immunology
TL;DR:
The first single-cell gene expression analysis in zebrafish blood is reported to distinguish major blood lineages, identify new cell types, and delineate heterogeneity in T cell leukemia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019
2016 journal article
Liver metal levels and expression of genes related to iron homeostasis in rhesus monkeys after inhalational manganese exposure
Data in Brief, 6, 989–997.
author keywords: Inhalation; Iron; Manganese; Monkey
TL;DR:
Liver manganese and iron levels were linearly correlated although only the intermediate mangansese exposure level (0.3 mg Mn/m3) led to a statistically significant increase in liver iron levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 21, 2019
2016 journal article
TransOmic analysis of forebrain sections in Sp2 conditional knockout embryonic mice using IR-MALDESI imaging of lipids and LC-MS/MS label-free proteomics
Analytical and Bioanalytical Chemistry, 408(13), 3453–3474.
author keywords: IR-MALDESI; Proteomics; Lipidomics; Mass spectrometry imaging; Embryonic brain
MeSH headings : Animals; Chromatography, Liquid / methods; Lipids / analysis; Mass Spectrometry / methods; Mice; Mice, Knockout; Prosencephalon / embryology; Prosencephalon / metabolism; Sp2 Transcription Factor / genetics; Spectrophotometry, Infrared / methods; Transcriptome
TL;DR:
An integrated approach for systematic analysis of the “lipidome” in tissue revealed many specific changes to fundamental cellular processes and biosynthetic pathways in the cerebral cortices of Sp2-cKO embryos.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 20, 2019
2016 journal article
Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism
Cell Host & Microbe, 19(2), 254–266.
MeSH headings : Animals; Disease Models, Animal; Ferrets; Gene Expression; Host-Pathogen Interactions; Humans; Influenza A Virus, H1N1 Subtype / physiology; Influenza, Human / epidemiology; Influenza, Human / genetics; Influenza, Human / metabolism; Influenza, Human / pathology; Lipid Metabolism; Lipids / chemistry; Lung / metabolism; Lung / pathology; Lung / virology; Metabolomics
TL;DR:
An extensive and systematic profiling of lipids, metabolites, and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses finds enrichment of distinct T cell subpopulations in the trachea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019
2016 journal article
FCGR2C Polymorphisms Associated with HIV-1 Vaccine Protection Are Linked to Altered Gene Expression of Fc-γ Receptors in Human B Cells
PLOS ONE, 11(3), e0152425.
Ed(s): J. Tang
MeSH headings : AIDS Vaccines / therapeutic use; Alleles; Alternative Splicing; B-Lymphocytes / cytology; B-Lymphocytes / metabolism; B-Lymphocytes / virology; Europe; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation; HIV Infections / genetics; HIV Infections / prevention & control; HIV-1; Homozygote; Humans; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Receptors, Fc; Receptors, IgG / biosynthesis; Receptors, IgG / genetics; Receptors, Immunologic / genetics; Receptors, Immunologic / metabolism; Sequence Analysis, RNA
TL;DR:
The results suggest that the expression of FcγR genes is influenced by these SNPs either directly or in linkage with other causal variants, and motivate further investigations into the potential for a causal association of expression and alternative splicing of FCGR2C and other FcβR genes with the HIV-1 vaccine protection in the RV144 trial and other similar studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019
2016 journal article
Correction: Comparison of Active Drug Concentrations in the Pulmonary Epithelial Lining Fluid and Interstitial Fluid of Calves Injected with Enrofloxacin, Florfenicol, Ceftiofur, or Tulathromycin
PLOS ONE, 11(7), e0159219.
TL;DR:
This research presents a novel probabilistic procedure that allows for direct measurement of the response of the immune system to earthquake-triggered landsliding.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: June 8, 2019
2016 journal article
Comparison of active drug concentrations in the pulmonary epithelial lining fluid and interstitial fluid of calves injected with enrofloxacin, florfenicol, ceftiofur, or tulathromycin
PLoS One, 11(2), e0149100.
Ed(s): J. Torrelles
MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Biological Availability; Cattle; Cephalosporins / blood; Cephalosporins / pharmacokinetics; Cross-Over Studies; Disaccharides / blood; Disaccharides / pharmacokinetics; Enrofloxacin; Epithelial Cells / metabolism; Extracellular Fluid / chemistry; Extracellular Fluid / metabolism; Fluoroquinolones / blood; Fluoroquinolones / pharmacokinetics; Heterocyclic Compounds / blood; Heterocyclic Compounds / pharmacokinetics; Lung / metabolism; Male; Mannheimia haemolytica / drug effects; Mannheimia haemolytica / growth & development; Microbial Sensitivity Tests; Respiratory Mucosa / metabolism; Thiamphenicol / analogs & derivatives; Thiamphenicol / blood; Thiamphenicol / pharmacokinetics; Veterinary Drugs / blood; Veterinary Drugs / pharmacokinetics
TL;DR:
The bronchial concentrations were higher than the plasma or interstitial concentrations, with over 900% penetration to the airways, and the tulathromycin concentrations achieved were lower than the MIC of susceptible bacteria at most time points.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 8, 2019
2016 journal article
How to (properly) determine the beyond-use date and stability of a compounded formulation for pets
Journal of Feline Medicine & Surgery, 18(4), 364–365.
Source: NC State University Libraries
Added: April 13, 2019
2016 chapter
Drug Formulary, Appendix IX
In L. P. Tilley & F. W. K. Smith (Eds.), Blackwells's Five Minute Veterinary Consult: Canine and Feline (6th ed., pp. 1445–1548). Wiley Blackwell.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: April 5, 2019
2016 journal article
Antimicrobial susceptibility testing for feline urinary tract isolates
Journal of Feline Medicine and Surgery, 18(2), 183–184.
TL;DR:
The Veterinary Antimicrobial Susceptibility Testing (VAST) subcommittee of the Clinical and Laboratory Standards Institute (CLSI) with regard to the paper by Lund et al,1 ‘Antimicrobial susceptibility in bacterial isolates from Norwegian cats with lower urinary tract disease’ is written.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: March 2, 2019
2016 journal article
POPULATION PHARMACOKINETICS OF ENROFLOXACIN AND ITS METABOLITE CIPROFLOXACIN IN THE GREEN SEA URCHIN (STRONGYLOCENTROTUS DROEBACHIENSIS) FOLLOWING INTRACOELOMIC AND IMMERSION ADMINISTRATION
Journal of Zoo and Wildlife Medicine, 47(1), 175–186.
author keywords: Ciprofloxacin; echinoderms; enrofloxacin; green sea urchin; pharmacokinetics; Strongylocentrotus droebachiensis
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Ciprofloxacin / administration & dosage; Ciprofloxacin / pharmacokinetics; Drug Administration Routes; Enrofloxacin; Fluoroquinolones / administration & dosage; Fluoroquinolones / pharmacokinetics; Strongylocentrotus / metabolism
TL;DR:
The concentrations of enrofloxacin achieved far exceeded minimum inhibitory concentrations reported for teleost pathogens, indicating minimal production of this metabolite in the green sea urchin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: March 2, 2019
2016 journal article
The identification of additional zebrafish DICP genes reveals haplotype variation and linkage to MHC class I genes.
http://europepmc.org/abstract/med/26801775
Source: ORCID
Added: February 13, 2019
2016 journal article
Angiopellosis as an Alternative Mechanism of Cell Extravasation
STEM CELLS, 35(1), 170–180.
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
TL;DR:
In injected cardiac and mesenchymal stem cells, the vascular wall undergoes an extensive remodeling to allow the cell to exit the lumen, while the injected cell remains distinctively passive in activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries, Crossref
Added: February 13, 2019
2016 journal article
Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish
Protein Science, 25(11), 2076–2088.
author keywords: phage display substrate library; substrate recognition; Danio rerio; apoptosis
MeSH headings : Allosteric Regulation; Animals; Caspase 3 / chemistry; Crystallography, X-Ray; Molecular Dynamics Simulation; Peptide Library; Substrate Specificity; Zebrafish
TL;DR:
The structure of zebrafish Casp3a is determined to 2.28Å resolution by X‐ray crystallography, and the results suggest that a limited number of amino acid substitutions near the active site result in plasticity of the S4 sub‐site by increasing flexibility of one active site loop and by affecting hydrogen‐bonding with substrate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 13, 2019
2016 journal article
Cell cycle Start is coupled to entry into the yeast metabolic cycle across diverse strains and growth rates.
Molecular Biology of the Cell, 27(1), 64–74,
MeSH headings : Biological Clocks / physiology; Cell Cycle / genetics; Cell Cycle / physiology; Cell Division / genetics; Cell Division / physiology; DNA Replication; Oxygen / metabolism; Oxygen Consumption / physiology; Partial Pressure; Saccharomycetales / cytology; Saccharomycetales / metabolism
TL;DR:
The interaction of two oscillators (cell division cycle and yeast metabolic cycle) with different frequencies is studied and Cell cycle Start is coupled with the initiation of high oxygen consumption and breakdown of storage carbohydrates across diverse strains and different growth rates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2016 journal article
Punctuated evolution and transitional hybrid network in an ancestral cell cycle of fungi
ELife, 5.
MeSH headings : Cell Cycle; Cell Cycle Proteins / genetics; Cell Cycle Proteins / metabolism; Evolution, Molecular; Fungi / cytology; Fungi / genetics; Fungi / physiology; Gene Transfer, Horizontal; Transcription Factors / genetics; Transcription Factors / metabolism
Source: ORCID
Added: February 11, 2019
2016 journal article
Spinal Cord Hamartomatous Myelodysplasia in 2 Horses With Clinical Neurologic Deficits
Veterinary Pathology, 53(4), 844–846.
author keywords: ataxia; hamartoma; horse; hydromyelia; muscle spasm; myelodysplasia; spinal cord
MeSH headings : Animals; Ataxia / pathology; Ataxia / veterinary; Hamartoma / diagnosis; Hamartoma / pathology; Hamartoma / veterinary; Hindlimb / pathology; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Neural Tube Defects / diagnosis; Neural Tube Defects / pathology; Neural Tube Defects / veterinary; Spasm / pathology; Spasm / veterinary; Spinal Cord / pathology
TL;DR:
Two horses euthanized for neurologic deficits were diagnosed with hamartomatous myelodysplasia of the spinal cord, which had focal disorganization of the white and gray matter of the cerebral spinal cord forming a mass interspersed with neurons, glial cells, and disoriented axon bundles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2016 journal article
Vibratory urticaria associated with a missense variant in ADGRE2
New England Journal of Medicine, 374(7), 656–663.
Contributors: S. Boyden*, A. Desai*, G. Cruse* , M. Young*, H. Bolan*, L. Scott *, A. Robin Eisch*, R. Daniel Long*
MeSH headings : Biopsy; Cell Degranulation / genetics; Female; Histamine / blood; Humans; Lebanon; Male; Mast Cells / physiology; Middle Aged; Mutation, Missense; Pedigree; Receptors, G-Protein-Coupled / genetics; Receptors, G-Protein-Coupled / metabolism; Skin / pathology; Urticaria / blood; Urticaria / etiology; Urticaria / genetics; Vibration / adverse effects
TL;DR:
It is shown that the previously unknown missense substitution in ADGRE2 probably destabilizes an autoinhibitory subunit interaction, sensitizing mast cells to IgE-independent vibration-induced degranulation, and cosegregating with vibratory urticaria in two large kindreds.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2016 journal article
Mast cells in airway diseases and interstitial lung disease
European Journal of Pharmacology, 778, 125–138.
Contributors: G. Cruse* & P. Bradding *
author keywords: Mast cell; Asthma; Airway diseases; Interstitial lung disease
MeSH headings : Animals; Cell Proliferation; Humans; Lung Diseases, Interstitial / immunology; Lung Diseases, Interstitial / microbiology; Mast Cells / microbiology; Mast Cells / pathology
TL;DR:
The role that mast cells play in airway diseases is discussed and how mast cell microlocalisation within specific lung compartments and their cellular interactions are likely to be critical for their effector function in disease are highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
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