Works Published in 2018

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Displaying works 1 - 20 of 174 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2018 journal article

Prognostic significance of hypermethylation of death-associated protein kinase (DAPK) gene CpG island in dogs with high-grade B-cell lymphoma.

Veterinary and Comparative Oncology, 3.

MeSH headings : Animals; CpG Islands / genetics; DNA Methylation / genetics; Death-Associated Protein Kinases / genetics; Dog Diseases / diagnosis; Dog Diseases / genetics; Dog Diseases / mortality; Dogs; Female; Lymphoma, B-Cell / diagnosis; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / mortality; Lymphoma, B-Cell / veterinary; Male; Prognosis; Retrospective Studies; Survival Analysis
TL;DR: Overall, hypermethylation of the DAPK CpG island was a negative prognostic factor in canine high-grade B-cell lymphoma. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: May 23, 2023

2018 journal article

A New Era of Cardiac Cell Therapy: Opportunities and Challenges

Advanced Healthcare Materials, 8(2), 1801011.

MeSH headings : Animals; Biocompatible Materials / metabolism; Cell- and Tissue-Based Therapy / methods; Endocarditis / metabolism; Endocarditis / therapy; Heart Diseases / metabolism; Heart Diseases / therapy; Humans; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / physiology; Myocarditis / metabolism; Myocarditis / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Nanomedicine / methods; Paracrine Communication; Tissue Engineering / methods
TL;DR: The next generation of cell‐based MI therapies will identify and isolate cell products and derivatives, integrate them with biocompatible materials and technologies, and use them for the regeneration of damaged myocardial tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 23, 2023

2018 journal article

In situ cardiac regeneration by using neuropeptide substance P and IGF-1C peptide eluting heart patches

Regenerative Biomaterials, 5(5), 303–316.

TL;DR: Data suggest that SP and IGF-1C peptides may act synergistically for in situ tissue repair in cardiac patches developed to develop cardiac patches capable of simultaneously eluting substance P (SP) and insulin-like growth factor- 1C (IGF-1 C) peptide. (via Semantic Scholar)
Source: ORCID
Added: April 19, 2023

2018 journal article

Prostaglandin E<sub>2</sub> hydrogel improves cutaneous wound healing via M2 macrophages polarization

Theranostics, 8(19), 5348–5361.

By: S. Zhang*, Y. Liu*, X. Zhang*, D. Zhu*, X. Qi*, X. Cao*, Y. Fang*, Y. Che* ...

Contributors: S. Zhang*, Y. Liu*, X. Zhang*, D. Zhu*, X. Qi*, X. Cao*, Y. Fang*, Y. Che* ...

MeSH headings : Animals; Cells, Cultured; Chitosan / administration & dosage; Dinoprostone / administration & dosage; Disease Models, Animal; Drug Carriers / administration & dosage; Hydrogel, Polyethylene Glycol Dimethacrylate / administration & dosage; Immunologic Factors / administration & dosage; Inflammation / pathology; Luminescent Measurements; Macrophage Activation / drug effects; Macrophages, Peritoneal / drug effects; Macrophages, Peritoneal / immunology; Mice; Molecular Imaging; Neovascularization, Physiologic / drug effects; Treatment Outcome; Wound Healing / drug effects; Wounds and Injuries / therapy
TL;DR: Molecular imaging results showed that the prolonged release of PGE2 could ameliorate inflammation by promoting the M2 phenotypic transformation of macrophages and highlighted the potential of CS+PGE2 hydrogel as a novel therapeutic strategy for promoting tissue regeneration via M2 macrophage polarization. (via Semantic Scholar)
Source: ORCID
Added: April 19, 2023

2018 journal article

Expression and clinical significance of CXC-chemokine ligand 5 in renal cell carcinoma

Chinese Journal of Clinical Oncology, 45(16), 838–843.

Contributors: G. Feng*, H. Li*, D. Zhu*, Y. Zhang*, G. Song*, Z. Zhang*, M. Chen*, J. Du*, X. Yao

Source: ORCID
Added: April 19, 2023

2018 chapter

Canine Biliary Mucocele

In J. D. Bonagura & D. Twedt (Eds.), Current Veterinary Therapy XVI (16th ed.). W.B. Saunder’s Co. Philadelphia.

By: J. Gookin, G. Seiler, K. Mathews & J. Cullen

Ed(s): J. Bonagura & D. Twedt

Source: NC State University Libraries
Added: September 8, 2022

2018 chapter

Protozoal Gastrointestinal Disease

In J. D. Bonagura & D. Twedt (Eds.), Current Veterinary Therapy XVI (16th ed.). Philadelphia: W.B. Saunder’s Co.

By: J. Gookin & M. Lappin

Ed(s): J. Bonagura & D. Twedt

Source: NC State University Libraries
Added: September 8, 2022

2018 journal article

The evolution of a G1/S transcriptional network in yeasts

Current Genetics.

Contributors: A. Hendler*, E. Medina*, N. Buchler*, R. Bruin* & A. Aharoni*

author keywords: Cell cycle; Evolution; Gene expression; G1-to-S transition; MBF and SBF
MeSH headings : Biological Evolution; Evolution, Molecular; G1 Phase / genetics; Gene Expression Regulation, Fungal; Gene Regulatory Networks; S Phase / genetics; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism; Transcription Factors / genetics; Transcription Factors / metabolism; Transcription, Genetic; Yeasts / physiology
TL;DR: The co-evolution of G1/S transcriptional network is reviewed and the evolutionary dynamics and specificity of the MBF–MCB and SBF–SCB interactions in different fungal species are discussed. (via Semantic Scholar)
Source: ORCID
Added: February 16, 2022

2018 journal article

Peer learning as a tool to strengthen math skills in introductory chemistry laboratories

Chemistry Education Research and Practice, 19(1), 319–330.

UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: ORCID
Added: June 25, 2021

2018 journal article

Loss of ATM positively regulates Rac1 activity and cellular migration through oxidative stress.

Biochemical and Biophysical Research Communications.

Melissa Srougi

author keywords: ATM; Rac1; Reactive oxygen species; Migration
MeSH headings : Animals; Ataxia Telangiectasia Mutated Proteins / metabolism; Cell Movement; Enzyme Activation; HeLa Cells; Humans; Oxidative Stress; Rats; Reactive Oxygen Species / metabolism; rac1 GTP-Binding Protein / metabolism
TL;DR: It is shown that loss of ATM kinase activity elevates intracellular ROS, leading to Rac1 activation, which drives cytoskeletal rearrangements resulting in increased cellular spreading and motility. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: June 25, 2021

2018 journal article

Student-Designed High-Throughput Assays to Assess Effects of Growth Insults in Budding Yeast.

Journal of Microbiology & Biology Education.

Melissa Srougi

TL;DR: An open inquiry-based laboratory activity exploiting a small-scale high-throughput screening assay of the budding yeast S. cerevisiae is designed to promote active learning and introduce students to modern data collection and analysis techniques. (via Semantic Scholar)
Source: ORCID
Added: June 25, 2021

2018 chapter

Hormones Affecting Reproduction

In J. Riviere & M. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 674–690). New Jersey, USA: Wiley.

By: W. Baeumer, C. Bailey & J. Gadsby

Ed(s): J. Riviere & M. Papich

Source: NC State University Libraries
Added: October 23, 2020

2018 chapter

Antiprotozoal Drugs

In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1128–1165). Hoboken, NJ: Wiley Blackwell Publishing.

By: J. Davis & J. Gookin

Ed(s): J. Riviere & M. Papich

Source: NC State University Libraries
Added: October 21, 2020

2018 chapter

Trichomonosis

In F. Beugnet, L. Halos, & J. Guillot (Eds.), Textbook of Clinical Parasitology in Dogs and Cats. Zaragoza: Grupo Asís Biomedia.

By: J. Gookin

Ed(s): F. Beugnet, L. Halos & J. Guillot

Source: NC State University Libraries
Added: October 21, 2020

2018 journal article

Synergistically Enhancing the Therapeutic Effect of Radiation Therapy with Radiation Activatable and Reactive Oxygen Species-Releasing Nanostructures

ACS Nano, 12(5), 4946–4958.

By: K. Cheng*, M. Sano*, C. Jenkins*, G. Zhang*, D. Vernekohl*, W. Zhao*, C. Wei*, Y. Zhang* ...

author keywords: radiation/chemotherapy; radio sensitizer; reactive oxygen species; gold-titanium oxide nanoparticles; heterogeneous interface; triple-negative breast cancers
MeSH headings : Animals; Apoptosis; Biocompatible Materials / chemistry; Cell Line, Tumor; Cell Survival; Female; Gold / chemistry; Humans; Metal Nanoparticles / chemistry; Mice, Nude; Neoplasm Transplantation; Polyethylene Glycols / chemistry; Radiation-Sensitizing Agents / chemistry; Radiation-Sensitizing Agents / therapeutic use; Reactive Oxygen Species / metabolism; Tissue Distribution; Titanium / chemistry; Triple Negative Breast Neoplasms / metabolism; Triple Negative Breast Neoplasms / radiotherapy
TL;DR: Significant tumor growth suppression and overall improvement in survival rate in a TNBC tumor model have been successfully demonstrated under DAT uptake for a radio-sensitized radiation therapy. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2018 journal article

Optimization of a single insertion electrode array for the creation of clinically relevant ablations using high-frequency irreversible electroporation

Computers in Biology and Medicine, 95, 107–117.

By: M. Sano n, M. DeWitt*, S. Teeter n & L. Xing*

author keywords: Focal ablation; HFIRE; Cancer therapy; Non-thermal; Device modeling; Finite element model
MeSH headings : Animals; Cattle; Electrodes; Electroporation / methods; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Models, Theoretical
TL;DR: Numerical simulations develop numerical simulations that demonstrate the potential for clinically relevant ablations with H-FIRE delivered via a single insertion technique comprised of an expandable array and a distally placed grounding pad and indicate that in vivo investigation of asingle insertion array and grounding pad are warranted. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2018 journal article

Effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone preventing movement in female dogs

Veterinary Anaesthesia and Analgesia, 45(6), 885.e2.

By: K. Bennett*, R. Seddighi*, K. Moorhead*, K. Messenger n, S. Cox*, X. Sun*, K. Pasloske, T. Doherty*

Source: Crossref
Added: February 24, 2020

2018 journal article

A comprehensive genomic history of extinct and living elephants

Proceedings of the National Academy of Sciences, 115(11), E2566–E2574.

By: E. Palkopoulou*, M. Lipson*, S. Mallick*, S. Nielsen*, N. Rohland*, S. Baleka*, E. Karpinski*, A. Ivancevic* ...

author keywords: paleogenomics; elephantid evolution; mammoth; admixture; species divergence
MeSH headings : Animals; Elephants / classification; Elephants / genetics; Evolution, Molecular; Extinction, Biological; Fossils; Gene Flow; Genome; Genomics / history; History, Ancient; Mammoths / classification; Mammoths / genetics; Mastodons / classification; Mastodons / genetics; Phylogeny
TL;DR: It is shown that interspecies hybridization has been a recurrent feature of elephantid evolution, and the genetic makeup of the straight-tusked elephant, previously placed as a sister group to African forest elephants based on lower coverage data, in fact comprises three major components. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Crossref
Added: February 21, 2020

2018 journal article

Growth kinetics of endosymbiont Wolbachia in the common bed bug, Cimex lectularius

Scientific Reports, 8(1).

MeSH headings : Animals; Bedbugs / microbiology; DNA / genetics; Female; Kinetics; Larva / microbiology; Symbiosis; Wolbachia / growth & development
TL;DR: It is highlighted that wCle is dynamic during bed bug development, changing relative to life stage, intermolt stage, and blood-fed status, and the observed quantitative modulation of wCle during the bed bug life cycle and during periods of starvation may explain the disparities in wCle infections reported in field-collected C. lectularius. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Crossref
Added: February 21, 2020

2018 journal article

To scratch an itch: Establishing a mouse model to determine active brain areas involved in acute histaminergic itch

IBRO Reports, 5, 67–73.

By: S. Ehling n, A. Butler n, S. Thi n, H. Ghashghaei n & W. Bäumer n

author keywords: c-fos; Itch; Brain; Medial habenula; Histamine H4 receptor
TL;DR: The specific histamine H4 receptor agonist ST-1006 induces acute itch in mice and selective H4R activation in the skin increases neuronal activity in the medial habenula. (via Semantic Scholar)
Source: Crossref
Added: February 21, 2020

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