Works Published in 2004
Displaying works 1 - 20 of 102 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2004 book
Cephalosporins in veterinary medicine
Parsippany-Troy Hills, NJ: Pfizer Animal Health.
Source: NC State University Libraries
Added: February 5, 2022
2004 journal article
Development of fetuses from in vitro produced and cloned bovine embryos
Journal of Animal Science, 82(Supplement 13), E53–E62.
MeSH headings : Animals; Cattle / embryology; Cattle / genetics; Cattle / growth & development; Cloning, Organism / adverse effects; Cloning, Organism / veterinary; Embryo Culture Techniques / veterinary; Embryo Transfer / adverse effects; Embryo Transfer / veterinary; Embryonic Development / genetics; Embryonic Development / physiology; Female; Fertilization in Vitro / adverse effects; Fertilization in Vitro / veterinary; Fetal Development / genetics; Fetal Development / physiology; Gene Expression Regulation, Developmental / physiology; Male; Pregnancy
TL;DR:
The effects of in vitro production and cloning on bovine embryo and fetal development are examined, including abnormalities in the development of fetuses, placentas, and offspring following transfer of cloned embryos.
(via Semantic Scholar)
Source: NC State University Libraries
Added: October 29, 2021
2004 journal article
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium
Laboratory Investigation, 84(5), 562–572.
author keywords: canine; endothelial cells; angiosarcoma; angiogenesis; CD117; NFAT; nicotine
MeSH headings : Animals; Antigens, CD / metabolism; Cell Adhesion; Cell Division; Cell Line, Tumor; Cell Movement; DNA, Neoplasm / analysis; DNA, Neoplasm / genetics; Dog Diseases / pathology; Dog Diseases / physiopathology; Dogs; Endothelium, Vascular / pathology; Hemangiosarcoma / blood supply; Hemangiosarcoma / pathology; Hemangiosarcoma / physiopathology; Hemangiosarcoma / veterinary; Humans; Models, Biological; Neovascularization, Pathologic; Ploidies; Vascular Endothelial Growth Factor A / metabolism
TL;DR:
It is shown that expression of CD117 (c-Kit) can distinguish primitive (malignant) from mature (benign) proliferative endothelial lesions, and eight independent cell lines derived from canine HSA explants are described.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: September 18, 2021
2004 journal article
Taking it Online – the Effects of Delivery Medium and Facilitator on Student Achievement in Problem-Based Learning
Journal of Interactive Online Learning, 3(2).
Source: NC State University Libraries
Added: April 24, 2021
2004 journal article
35 Analysis of epigenetic modifications and genomic imprinting in nuclear transfer derived Bos Gaurus x B. Taurus Concepti
Reproduction, Fertility and Development, 16(2), 140.
TL;DR:
The use of a bovine interspecies model for the assessment and characterization of epigenetic modifications and genomic imprinting in 40-day-old female nuclear transfer (NT)-derived fetuses and placentas and methylation analysis of the XIST Differentially Methylated Region indicates that cloning is associated with increased levels of methylation in selected genomic regions in the chorion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: April 4, 2021
2004 journal article
A high-resolution comparative map of canine Chromosome 5q14.3-q33 constructed utilizing the 1.5x canine genomesequence
Mammalian Genome, 15(7), 544–551.
MeSH headings : Animals; Chromosome Mapping; Chromosomes / ultrastructure; Chromosomes, Artificial, Bacterial; Crosses, Genetic; DNA / metabolism; DNA Primers / chemistry; Dogs; Gene Library; Genetic Linkage; Genetic Predisposition to Disease; Genome; Genome, Human; Genotype; Humans; Microsatellite Repeats; Models, Genetic; Polymorphism, Single Nucleotide; Species Specificity
TL;DR:
This current mapping effort on CFA5 expands the degree to which initial findings of linkage in canine families can be followed by successful positional cloning efforts and increases the value of the human genome sequence for defining candidate genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Crossref
Added: December 29, 2020
2004 journal article
Early activation of Wnt β-catenin system following a massive small bowel resection in mice
Journal of Surgical Research, 121(2), 309–310.
TL;DR:
Early changes in gene expression of the soluble intestinal Wnts and their downstream targets responsible for proliferation, migration, and differentiation towards secretory lineages in mature epithelium are determined.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
67ORGAN WEIGHT VARIATION IN CLONED PIGS
Reproduction, Fertility and Development, 16(2), 155.
TL;DR:
Both absolute and corrected weights indicated that there is a high degree of variation in some of the organs among a group of identical clones, indicating that some organs in cloned animals have a high level of weight variability.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
343NUCLEAR LOCALIZATION SIGNAL AND CELL SYNCHRONY ENHANCES GENE TARGETING EFFICIENCY IN FETAL BOVINE FIBROBLASTS
Reproduction, Fertility and Development, 16(2), 291.
TL;DR:
Evidence is presented that the use of a nuclear localization signal (nls) and S-phase cell cycle synchronization by thymidine block enhances targeting efficiency at the hypoxanthine phosphoribosyl transferase locus in primary fetal bovine fibroblasts.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Dose-dependent transitions in mechanisms of toxicity: case studies
Toxicology and Applied Pharmacology, 201(3), 226–294.
author keywords: dose-dependent transitions; mechanisms of toxicity; dose response; acetaminophen; butadiene; ethylene glycol; formaldehyde; manganese; methylene chloride; peroxisome proliferator-activated receptor; progesterone/hydroxyflutamide; propylene oxide; vinyl acetate; vinyl chloride; vinylidene chloride; zinc
MeSH headings : Acetaminophen / administration & dosage; Acetaminophen / pharmacokinetics; Acetaminophen / toxicity; Analgesics, Non-Narcotic / administration & dosage; Analgesics, Non-Narcotic / pharmacokinetics; Analgesics, Non-Narcotic / toxicity; Androgen Antagonists / administration & dosage; Androgen Antagonists / pharmacokinetics; Androgen Antagonists / toxicity; Animals; Butadienes / administration & dosage; Butadienes / pharmacokinetics; Butadienes / toxicity; Dichloroethylenes / administration & dosage; Dichloroethylenes / pharmacokinetics; Dichloroethylenes / toxicity; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions / chemically induced; Drug-Related Side Effects and Adverse Reactions / metabolism; Epoxy Compounds / administration & dosage; Epoxy Compounds / pharmacokinetics; Epoxy Compounds / toxicity; Ethylene Glycol / administration & dosage; Ethylene Glycol / pharmacokinetics; Ethylene Glycol / toxicity; Flutamide / administration & dosage; Flutamide / analogs & derivatives; Flutamide / pharmacokinetics; Flutamide / toxicity; Formaldehyde / administration & dosage; Formaldehyde / pharmacokinetics; Formaldehyde / toxicity; Humans; Manganese / administration & dosage; Manganese / pharmacokinetics; Manganese Poisoning / metabolism; Methylene Chloride / administration & dosage; Methylene Chloride / pharmacokinetics; Methylene Chloride / toxicity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptors / physiology; Progesterone / administration & dosage; Progesterone / pharmacokinetics; Progesterone / toxicity; Vinyl Compounds / administration & dosage; Vinyl Compounds / pharmacokinetics; Vinyl Compounds / toxicity; Zinc / administration & dosage; Zinc / pharmacokinetics; Zinc / toxicity
TL;DR:
A group of academic, government, and industry scientists, formed under the leadership of the ILSI Health and Environmental Sciences Institute (HESI), developed a series of case studies to illustrate the existence of dose-dependent transitions in mechanisms of toxicity.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Dose-dependent transitions in mechanisms of toxicity
Toxicology and Applied Pharmacology, 201(3), 203–225.
author keywords: dose-dependent transitions; mechanisms of toxicity; dose-response
MeSH headings : Animals; DNA Adducts / drug effects; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Humans; Inactivation, Metabolic; Research Design; Risk Assessment
TL;DR:
This paper addresses the issues discussed at both workshops, and presents the consensus conclusions drawn by expert participants on the impact of dose-dependent transitions on the risk assessment process.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Respiratory tract toxicity of inhaled hydrogen sulfide in Fischer-344 rats, Sprague–Dawley rats, and B6C3F1 mice following subchronic (90-day) exposure
Toxicology and Applied Pharmacology, 198(1), 29–39.
author keywords: rat; mouse; inhalation; hydrogen sulfide; nose; lung; toxicity; pathology
MeSH headings : Administration, Inhalation; Air Pollutants / toxicity; Animals; Body Weight / drug effects; Bronchi / drug effects; Bronchi / pathology; Dose-Response Relationship, Drug; Eating / drug effects; Epithelial Cells / drug effects; Epithelial Cells / pathology; Female; Hydrogen Sulfide / administration & dosage; Hydrogen Sulfide / toxicity; Male; Mice; Mice, Inbred Strains; No-Observed-Adverse-Effect Level; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Respiratory System / drug effects; Respiratory System / pathology; Rhinitis / chemically induced; Rhinitis / pathology; Species Specificity; Toxicity Tests, Chronic; Turbinates / drug effects; Turbinates / pathology
TL;DR:
The results confirm that the rodent nose, and less so the lung, are highly sensitive to H2S-induced toxicity, with 10 ppm representing the NOAEL for ONL following subchronic inhalation.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Nasal Toxicity of Manganese Sulfate and Manganese Phosphate in Young Male Rats Following Subchronic (13-Week) Inhalation Exposure
Inhalation Toxicology, 16(6-7), 481–488.
MeSH headings : Air Pollutants / toxicity; Animals; Cerebellum / metabolism; Corpus Striatum / metabolism; Dose-Response Relationship, Drug; Drug Administration Schedule; Glial Fibrillary Acidic Protein / metabolism; Inhalation Exposure; Male; Manganese Compounds / administration & dosage; Manganese Compounds / pharmacokinetics; Nasal Mucosa / drug effects; Nasal Mucosa / metabolism; Nasal Mucosa / pathology; Olfactory Bulb / metabolism; Organometallic Compounds / administration & dosage; Organometallic Compounds / pharmacokinetics; Organometallic Compounds / toxicity; Rats; Rats, Inbred Strains; Sulfates / administration & dosage; Sulfates / pharmacokinetics; Sulfates / toxicity
TL;DR:
It is confirmed that high-doseManganese inhalation can result in nasal toxicity (irritation) and increased delivery of manganese to the brain; however, it is not confirmed that mangane inhalation would result in altered brain GFAP concentrations.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2004 journal article
Old age and gender influence the pharmacokinetics of inhaled manganese sulfate and manganese phosphate in rats
Toxicology and Applied Pharmacology, 197(2), 113–124.
Source: Crossref
Added: February 24, 2020
2004 journal article
Old age and gender influence the pharmacokinetics of inhaled manganese sulfate and manganese phosphate in rats
Toxicology and Applied Pharmacology, 197(2), 113–124.
author keywords: age; gender; manganese
MeSH headings : Administration, Inhalation; Aging / metabolism; Animals; Body Weight / drug effects; Female; Male; Manganese / metabolism; Manganese Compounds / administration & dosage; Manganese Compounds / pharmacokinetics; Neostriatum / drug effects; Neostriatum / metabolism; Organ Size / drug effects; Organometallic Compounds / administration & dosage; Organometallic Compounds / pharmacokinetics; Organometallic Compounds / toxicity; Radioisotopes; Rats; Sex Characteristics; Sulfates / administration & dosage; Sulfates / pharmacokinetics; Sulfates / toxicity; Tissue Distribution
TL;DR:
Gender and age did not affect manganese delivery to the striatum, a known target site for neurotoxicity in humans, but did influenceManganese concentrations in other tissues, and end-of-exposure olfactory bulb, lung, and blood manganes concentrations were higher in young male rats than in female or aged male rats and may reflect a portal-of theentry effect.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2004 journal article
Manganese exposure and induced oxidative stress in the rat brain
Science of The Total Environment, 334-335, 409–416.
author keywords: brain; manganese; neurotoxicity; glutathione; metallothionein; glutamine synthetase; MMT
MeSH headings : Animals; Antioxidants / pharmacology; Biomarkers; Brain / drug effects; Brain / pathology; Environmental Pollutants / adverse effects; Manganese / adverse effects; Oxidation-Reduction; Oxidative Stress; Rats
TL;DR:
The link between manganese neurotoxicity in the rat brain and common pathways to oxidative stress is examined, particularly in rat brain tissue.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2004 journal article
Health and environmental testing of manganese exhaust products from use of methylcyclopentadienyl manganese tricarbonyl in gasoline
Science of The Total Environment, 334-335, 397–408.
author keywords: methylcyclopentadienyl manganese tricarbonyl; MMT; manganese; pharmacokinetics
MeSH headings : Animals; Carcinogens, Environmental; Environmental Exposure; Gasoline; Humans; Manganese; Organometallic Compounds / adverse effects; Organometallic Compounds / analysis; Organometallic Compounds / pharmacokinetics; Public Health; Risk Assessment; Rodentia; Vehicle Emissions / analysis
TL;DR:
A great amount of toxicological research has been carried out during the past few years that provides data for use in developing a PBPK model in rodents, and these data add greatly to the existing body of knowledge regarding the relationship between Mn exposure and tissue disposition.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2004 journal article
Evaluation of the effects of premedication on gastroduodenoscopy in cats
Journal of the American Veterinary Medical Association, 225(4), 540–544.
MeSH headings : Analgesics / pharmacology; Anesthesia, General / methods; Anesthesia, General / veterinary; Anesthetics, Combined; Animals; Butorphanol / pharmacology; Cats / physiology; Cross-Over Studies; Duodenoscopy / methods; Duodenoscopy / veterinary; Female; Gastroscopy / methods; Gastroscopy / veterinary; Glycopyrrolate / pharmacology; Hydromorphone / pharmacology; Isoflurane; Ketamine; Medetomidine / pharmacology; Parasympatholytics / pharmacology; Preanesthetic Medication / methods; Preanesthetic Medication / veterinary; Random Allocation
TL;DR:
Hydromorphones, hydromorphone and glycopyrrolate, medetomidine, and butorphanol at the doses tested can be used satisfactorily to premedicate cats prior to general anesthesia for gastroduodenoscopy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Crossref
Added: July 27, 2019
2004 journal article
Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain
Nature Neuroscience, 7(12), 1319–1328.
MeSH headings : Animals; Animals, Newborn; Cell Movement / physiology; ErbB Receptors / biosynthesis; ErbB Receptors / genetics; ErbB Receptors / physiology; Mice; Mice, Knockout; Neurons / cytology; Neurons / enzymology; Prosencephalon / cytology; Prosencephalon / enzymology; Prosencephalon / growth & development; Receptor, ErbB-4
TL;DR:
It is suggested that ErbB4 activation helps to regulate the organization of neural chains that form the rostral migratory stream and influences the differentiation of olfactory interneuronal precursors.
(via Semantic Scholar)
Source: Crossref
Added: July 20, 2019
2004 chapter
Drug therapy for diseases of the central nervous system
In S. R. Platt & N. J. Olby (Eds.), BSAVA Manual of Canine and Feline Neurology (pp. 368–384). Quedgeley, Gloucester, England: British Small Animal Veterinary Association.
Ed(s): S. Platt & N. Olby
Source: NC State University Libraries
Added: June 8, 2019
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